METHOTREXATE SODIUM Reviews (METHOTREXATE SODIUM)Average Rating: 3.3 (383 Ratings)Filter ResultsCompare METHOTREXATE SODIUM with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on METHOTREXATE SODIUM: Reviews Summary | FDA Adverse Event Summary
| RATING | REASON | SIDE EFFECTS FOR METHOTREXATE SO | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 4 | Psoriasis and Psoriatic Arthritis | Extreme (well pretty bad anyway) nausea and extreme fatigue about 1-2 days after treatment day. I take 20 mg/week orally. I get bad nausea for about 4-5 days and extreme fatigue about 1-2 days after the treatment day. | I don't really like this medication. It does seem reasonably effective at helping my p and pa. It is very reasonably priced, but I worry about effects on my liver. The side effects such as nausea and fatigue are definitely adversely affecting my lifestyle and general outlook on life. I guess individuals need to weigh up the advantage versus the disadvantage for this (and every) medication. | M | 44 | 10 weeks | 9/9/2009 | 2 | Atypical RA | I felt extreme sleepiness which was helped by a triple espresso. Also felt drunk...stumbling and goofy. A little nausea that I remedied with pickled ginger. Feel like I want to sleep for a week. | This is my 2nd week of 12.5 mg. I know it can take 4 -6 weeks before any improvement is noted. Also on prednisone 5 mg/day. Had been on 40 mg which helped alot. 5 mg is not working so I hope I see an improvement with the MTX. | F | 52 | 2 weeks | 9/8/2009 | 1 | ra | hair loss, extreme fatigue after stopping, threw up everyday and liver toxicity. | F | 45 | 249 days | 8/14/2009 | 3 | PA and Psoriasis | Fatigue for first few days after taking it, loss of appetite | Taking 15 mg with folic acid. Has helped Psorasis greatly, verdict is out on PA. Have had several flare ups since on it - but dr said it could take 3-6 months for it to be effective. Plaquenil gave me a terrible Psorasis outbreak and this is the next step in trying to stablize my symptoms. | F | 45 | 2 months | 8/3/2009 | 3 | lung infiltrates lower WBC count | memory (short-term) recall; very tired, nausea, severe headaches; "spacey" type feeling; I believe hearing is starting to get affected | Started w/ 5 mg. have been increased to 20 mg. once per week; take 1 mg. folic acid daily; dislike drug but will wait to see if there is any benefit with reducing my lung inflammation and WBC count; was on azothioprine previously with similar side-effects experienced; MTX not as severe but definite memory (short-term) recall; extremely tired; severe headache (constant); nausea; symptoms reduce gradually then it is time to take next round | F | 45 | 7 months | 7/28/2009 | 3 | rheumatoid arthritis | fatigue, fatigue, fatigue! I feel a good bit of nausea for a day or two after I inject 1ml mtx once weekly, which is, as I am noticing, a rather low dose. I also feel more depressed than ever but not sure if the mtx is the cause or the general Dx of having RA and being unable to accept my limitations. | I also take plaquenil and folic acid daily as well as Enbrel once a week. So far I haven't had a reduction in symptoms, although I FEEL better but that might be because it's summertime. Another thing I noticed- swelling, pain, and immobility in my joints seemed so much better while I was at our beach house! I joked with my rheumatologist that I want a Rx to move there permanently. ANyone else noticed that? | F | 54 | 2 years | 7/22/2009 | 5 | rheumatoid arthritis | fatigue and bit of mental fog. One knee hurts if I 'overdo it', shedding hair worse than the cat!! Grows back though. | Got RA and went from hero to zero in 3 weeks. Landed in hospital and got 2.5 grams of prednisone intravenously and more directly into my knees. Got it under control, home in 5 days, off crutches in 3 weeks. Take 20mg of MTX per week since March 09, plus folic acid and colcalciferol. Starting to wean off 20mg of steroids. Blood work is coming back fine. RA symptoms largely gone. Will be interesting to see if the MTX can hold the fort once the steroids are off the menu. Take fish oil too. | F | 52 | 5 months | 7/12/2009 | 4 | Psoriatic Arthritis | none | Had no notable side effects but also had zero effect on my arthritis (up to max dose of 20mg/Week). My regular blood tests have always been fine. I am now on MTX + Humira (which works very well) and am lead to believe that the MTX decreases the chances of my developing resistance to Humira and improves its effectiveness but I have no way of confirming this. | M | 2.5 years | 7/11/2009 | 4 | psoriatic arthritis and psoriasis | memory loss, concentration difficulties; hair loss including lower lashes; continual sinus and ear infections due to lowered immune system; fatigue | I have been on this medication, up to 15mg 1Xweek, for 15 years. When I have gone off, I find my hands and feet hurt and feel hot continuously as well as a severe outbreak of psoriasis. It keeps these symptoms in check. I am also taking arava (for the past 8-9 years) which seems to improve the effectiveness. However, I am not happy with the memory loss or hair loss either for that matter! | F | 48 | 15 years | 7/7/2009 | 2 | Psoriatic Arhritis | Made me feel exhausted. Needed excessive amounts of sleep. I also suffer from dysthymic depression and the drug seemed to make this worse. In terms of PA, it worked ok but only 80% remission. | Didn't really improve my psoriasis at all. | M | 36 | 3 months | 7/4/2009 | 3 | JESSNERS INFILTRATE/URTICARIA | I feel utterly depressed and feel I need anger management,totally out of character for me and only started to be like this when my methotrexate got upped to 20mg about 6 months ago. I take 20mg on a Sunday evening and feel sick and tired as soon as I wake up on Monday morning. I get panic attacks/palpations regular and have chest pains and cannot breath, headaches and diarrea. I have been to casualty 6 times with breathing problems and needed to go onto oxygen and have ecg's and at 17 years old it is no fun. On arriving at casualty they sit on google to see what Jessners infiltrate is and the specialist will not help me or advice me whatsoever. I need help | It has helped my jessners which is blisters and lumps on the upper part of body and face. I have noticed that anxiety makes the lumps worse even on methotrexate. I just wish i could find someone with jessners for support. Can't hold a job down and cannot get disability allowance but poorly every day of the week. | F | 17 | 8 months | 6/22/2009 | 4 | Psoriac Arthritus | Nausea, Diziness (lack of balance), Tiredness | 7.5mg, side effects kicked in after about 5 weeks. Has helped the PA but feel rubbish for a couple of days after taking. The loss of balance is very disconcerting. Also on Folic Acid 3 days after. Only on it 3 months so far so will wait and see... | M | 45 | 3 months | 6/17/2009 | 3 | psoriatic arthritis | nauseau, temporary retardedness, osteoporosis | had to take this for PA, and it did put me in remission, at a price. I HATE this drug. Initially took it in pill form w/ several glasses of water-got so sick that to this day (this was over 10 yrs ago) I cannot drink water w/out feeling sick. Switched to shots that made it better. Took this for five years, it did put me in remission and am still in remission 5 years later but then found out after breaking shoulder I had osteoporosis at age 35. Eventually found out osteoporosis can be caused by mtx. yay. However, if you are prescribed this drug you probably need it. What're you gonna do? Just need to carefully weigh the advantage/disadvantage. I would suggest to try to limit the amount of time taking it if possible | F | 40 | 5 days | 6/14/2009 | 3 | Seronegative Inflammatory Arthritis | Fatigue, headaches, mouth sores, regular sore throat, heartburn, indigestion, slight hair loss, poor concentration, dry eyes, leg cramps, weight gain, loose stools. | Methotrexate has helped to a degree and brought my sed rate down, however it has not controlled my condition. In general each and every day I feel exhausted. I have pain daily with regular flare-ups. I tried Sulphasalazine previous to MTX and that did not agree with me at all. My Consultant has mentioned anti TNF therapy, and I have concerns regarding this, however of late I am wondering if it would be worth trying as I feel I cannot carry on the way I am. | F | 43 | 19 months | 5/25/2009 | 5 | Psotiatic Arthritis | When I was taking the pills, like one user, I became so sick, vivid dreams (at about 25 mg). My doctor switched me to subcutaneous shot injections that I give myself once a week and I am fine now. Methotrexate has given me my life back. I sometimes wake up with a headache but everything is minimal now | F | 12 years | 5/23/2009 | 2 | RA, fibromyalgia | I've been taking 25mg once a week. The day after taking it I would be so nauseous and tired I can't get out of bed. I stay extremely nauseous for the duration of the week. When the nausea finally subsides a bit, I have to take the drug again. If I climb just one flight of stairs, walk or stand for a long time, I become dizzy and my heart starts to race. I'm a student and I can't afford to feel so tired and weak all the time. I can't do the same activities my friends do, because I get too tired. I developed an underactive thyroid problem and I get stomach ulcers. I stopped taking it about a month ago, without telling my rheumatologist, and I'm not as tired anymore and there's no more nausea (thankfully). The pain has been worse though, especially in my hands, shoulders and hips. I've also gotten more headaches. But I almost prefer the extra pain to the fatigue and nausea. I want to discuss other treatment with my rheumatologist, but she brushes off my complaints and increases my dosage | The drug didn't seem to make much of a difference. I still got really bad flare ups while taking the drug (one especially painful one in my right ancle which rendered me unable to walk properly for about 3 weeks). | F | 22 | 2 years | 5/19/2009 | 5 | RA | The drug was amazing when I first started taking it and increased up to 20mg (x10 tablets), however after 3 years of taking I started to feel sick they day I took the drug and the day after. My dose has gradually decreased and I am now on 5mg, I still get the sickness and hate taking the drug and dread the day I have to take it. Although I cant complain I suppose as I have responded much better than some people might have. | Taking folic acid everyday except the day you take the methotrexate and also anti-sickness tablets may help | F | 26 | 3 years | 5/14/2009 | 4 | R A | I feel tired, and my memory is poor. Im not sure whether to put it down to the drug though. I am sure i am now experiencing bloating on the face ... | I stopped the drug completly last september to try for a third baby but within six months of being off the drug i was totally crippled by the RA and decided to give up on the baby idea and go back on methotraxate. It does work for me . | F | 30 | 10 years | 5/14/2009 | 3 | Psoriasis | Extreme fatigue, nausea, body pain, mouth sores, light nose bleeds, dizziness... | I am taking 8 pills (20mg/week). I have found the fatigue is horrible. I take my pills on a Friday because the two days following are worse for me. I can sleep all day on Saturday and recover Sunday. The 20mg prevents the psoriasis from getting worse (I have it pretty bad on my legs and am polka-dotted on my arms). For me, I would rather have a couple of cruddy days a week than deal with the itching, cracking, bleeding and general horrification that comes with psoriasis. To ebb the nausea, I have found slim-fast shakes work best. Plus, you get some nutrition. I go to a mostly vegetarian diet on the day I take MTX and the next day. Fruit and veggies keep me from throwing up. Meats and greasy foods seem to taste odd on those days and severely upset my stomach. Hopefully, some of this helps y'all | F | 27 | 6 months | 5/1/2009 | 4 | Undiagnosed Inflammatory Tumors | Can not say, because I am still on Prednisone and was on Warfarin, so my side effects could have been caused by them, too - stomach pain, blood blisters, fatigue, etc. My tumors went into remission with the prednisone, but I am weaning off that now and have been on 15mg oral MTX since January 2009. | Please be careful of taking aspirin, tylenol, advil, or prednisone with MTX. All of these can cause SERIOUS problems when taken with MTX. | F | 56 | 4 months | 4/28/2009 |