METHOTREXATE SODIUM Reviews (METHOTREXATE SODIUM)Average Rating: 3.3 (383 Ratings)Filter ResultsCompare METHOTREXATE SODIUM with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on METHOTREXATE SODIUM: Reviews Summary | FDA Adverse Event Summary
| RATING | REASON | SIDE EFFECTS FOR METHOTREXATE SO | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 3 | RA | severe stomach pain, nausea, fatigue, night sweats/chills, bruising, weakness, very tired, anorexia. | my 11y/o son started this drug 2 months ago and his quality of life has diminshed significantly. He is so sick most of the week and won't eat. Has lost 7 pounds in 6 weeks. Once he feels better, it is time for another injection. He has had improvement of the edema and pain in the joints. | M | 11 | 60 days .5mg IM 1X W | 8/19/2011 | 3 | Ankylosing Spondylitis | Very tired, very weak, mental fog, loss of memory, night sweats. Hot flashes and acne. (went thru menopause 20 yrs.ago!) Panic attacks. Very irritable sometimes. | Seems too early to judge drug yet. Adjusting schedule to cope with tiredness; groceries, chores, friends, etc. Am taking less Vicodin,etc; however still lot's of pain in back, hips, knees, hands... | F | 60 | 5 weeks 25 MG 1X W | 8/17/2011 | 4 | Psoriasis / Psoriatic arthritis | Tiredness and occasional nausea on days of treatment. Occasional diarrhea. | It is the second time I take MTX. The first time, at higher doses, I had to stop due to liver damage. My doctor won't put me on any other DMARDS as I have had chemotherapy too recently. I now take MTX 3 x 2.5mg per week (Friday morning, Friday night and Saturday morning). I feel very tired on Friday afternoon/evening and Saturday most of the day, but feel much better on Sunday and the rest of the week. The PA is almost completely gone (I can exercise, and went back to bicycling and hiking), and the swollen joints do not come back unless I exagerate with the exercise. The psoriasis is down to a minimun, but won't go away completely. All in all, I am satisfied with the drug, as I can walk an have a normal life. I just need to plan for quiet Fridays and Saturdays! | M | 48 | 4 months 2.5mg 3X W | 8/12/2011 | 3 | RA | Fatigue/lethargy, mouth ulcers, lack of concentration, loss of appetite, bloating, sweats, awake in the night every night. | take every saturday and folic acid 5mg on sunday. by sunday night the swollen mouth is there without fail - boy it hurts. didn't realise what i was suffering because of these meds. i just want to sit and cry some days for no reason, so agree with the PMT comments. on the plus side, i can walk again, i can sit here and type. on the downside, constant frown with weariness, lack of concentration now starting to badly effect work. | F | 45 | 5 months 20mg 1X W | 8/2/2011 | 3 | Inflammatory plaque-type Morphea | Nothing yet so I hope it stays this way | My doctor said that it takes time before you can see any results BUT some of my morphea patches look a lot lighter! So I hope it will only get better from now on | F | 22 | 2 weeks 7,5 MG 1X W | 6/14/2011 | 3 | RA | Took MTX for a couple of years for Rheumatoid Arthritis without any noticeable effects, then stopped for about six months after I was also diagnosed with Crohn's and had emergency surgery. Since resuming MTX, I feel very tired and "foggy" most of the time and have increasingly bad short-term memory loss (I also take Remicade, Prednisone (5 mg/day) and Plaquenil, so it could be due to a combo of these drugs). | This drug has helped a great deal with joint pain, especially in combination with Remicade, but the tiredness and fuzzy-brained feeling is bad enough that it would be impossible for me to have a full-time job. | F | 32 | 3 years 15 1X W | 4/26/2011 | 3 | psoriasis, psoriatic arthritis | dizzy, nauseaus, migraine | took methotrexate a few months ago for 5 weeks and eyes became dry and very inflamed. Got worse with each week and could not put in contact lenses. Doctors said it was not from drug but I stopped it and symtoms went away instantly. Now on it again for two week and withing hours of taking it last night I have a horrible headache and had a migraine aura last night. | F | 57 | 2 weeks 15mg 1X W | 4/21/2011 | 4 | first 4 weeks: extreme fatigue, dizziness, nausia, stomach pain next 2-3 days after Fri night dose week 5 : fatigue, diziness, stomach pain only next day after Fri night dose Menstral cycle disruption: for the first time in many years, my cycle was completely disrupted. The menstral fluid extremely low. Lingering spotting. Frequent virginal discharge. Loss of sex drive: before starting the medication, I had rather high sex drive and noticed that I have none now. | I take 15mg/week of MTX, 1mg/day Folic acid everyday, as prescribed. Feel I have somewhat more hair falling but I have a lot of hair to the extent I reduce the amount in hairsalon, so it does not concern me. (I am a Japanse female living in US) I was diagnosed with RA several month ago and was on SSZ but switching to MTX. I still have low/high (depends on the day) pain in my joints but my stiffness feels much lower. Hoping it will improve... I don't like this menstral cycle disturbance and extremely low menstral flow... I am scared if I am going to have an early menoposal / ovarian failure. But, still better than potetial disabled joints. By the way, I read that the menstral cycle disruption is a VERY COMMON KNOWN side affects -- from a Japanese rheomatologist conference's presentation. They said that doctors should inform this prior to a RX so that the patient would not get shocked. However, the doctors in US seem not to talk about this. Have not gotten my first post-MTX blood test yes (next week) so I cannot tell how my liver doing with this or over many years. Although I will have to give this medicine a chance for a while (it has been only 5 weeks) to see stronger effect on my joints (they still hurt but not severe), I already started to feel my fatigue level decreasing. Not sure of course if this is due to MTX. | F | 45 | 5 weeks 15 mg 1X W | 4/17/2011 | 4 | Multicentric Reticulohistiocytosis | Nausea the 2nd and 3rd day after taking it, also very tired on the 2nd and 3rd day. Fingertips and toes very cold. Weight loss. | I also have ulcerative colitis. Since I have been on the methotrexate, I have noticed an improvement with the U.C. I also have not had any cardiac or pulmonary issues (first time since 2009) So I definately think it is working. I did have a kidney stone a few weeks ago, but my GP did not think it had anything to do with the Methotrexate. | F | 40 | 2 months 12.5 mg 1X W | 4/5/2011 | 2 | RA | My main side effect while taking the oral methotrexate is bloating. The bloating is horrible and seems to be getting worse. Because of my sensitivities to meds, I was started out on 2.5MG once a week for 4 weeks then went up to two pills once a week. I'm on week 8 and will be begging for the injection. My bloating is so bad that I cry and the bloating is visible. I look like I'm pregnant it is that bad. | The longer I am on the med, the worse it gets. I take it Saturday evening. As the week goes on, it lessens but then Saturday comes and I have to start all over again. I was started out on the lowest possible dose because of sensitivities. I am not even at a 'normal' dose so I will be begging for the injections. It is hard to tell if it is doing anything for the RA because of the pain from bloating. | F | 33 | 8 weeks 2.5MG 2X W | 3/31/2011 | 2 | Severe fatigue, vertigo, fuzzy thinking, depression, generally not feeling well. | I was on methotrexate for the a year with no improvement in bone deterioration of wrists. Dr upped it from 4tablets to 6. Then I had liver problems. We then tried Embrell, Humira, Simponi, Simponi with Methotrexate. All with no improvement. Now I am back to only Methotrexate. Doctor upped it to 5 a week and I began having Diarhea, Vertigo and worsening fatigue. I am considering not taking it this week and calling the doctor. | F | 71 | 4 months 10 MG 1X W | 3/18/2011 | 3 | sarcoidosis | Tired, gasy, bloated....only the day of & a couple days after | F | 38 | 1 days 2.5 4X day | 3/17/2011 | 4 | RA | M | 44 | 20 years 10mg 1X W | 3/4/2011 | 3 | Rheumatoid Arthritis | Nausea off and on, hair loss but, that is better with the folic acid, dizziness. | I initially took injectable and that gave me more nausea and more hair loss and I didn't notice any decrease in symptoms. Now I take oral in combination with Remicade. Not sure if it really helps but, I am told it works in conjunction with the Remicade. | F | 38 | 2 years 12.5 mg 1X W | 3/2/2011 | 2 | Crohn's | extreme fatigue, lowered immune system/increase in cold or flu symptoms after I take it (sore throat, congestion, etc.), dry eyes, headache | It's amazing to read all of the comments because I've been feeling sicker lately and I thought it was from the Miralax I've been taking but maybe it's actually the methotrexate... or a combo of both? Maybe taking the Miralax decreases the amount of water available in my body (since it pulls it to the colon) which makes me feel the methotrexate side effects more. I'm not sure, but either way, I've been feeling pretty awful these past couple months. Maybe my body is finally reacting to the methotrexate? Or, maybe this is all just part of the Crohn's. Idk. Has anyone else had an increase in side effects/noticed a change over time or when taken with other meds? | F | 29 | 6 years 10 mg 1X W | 2/24/2011 | 1 | RA | liver poison ('toxicity') and related rashes, elevated blood pressure; Note: If you send me a question leave me your e-mail address or I cannot respond | I wished after my hospital trip that I had known what a powerful anti-oxidant coffee is and can cleanse the liver. However I have now discovered some natural cures can work better that any drug, which the body tries to reject as poison; such as honey and vinegar and vitamen B 100 complex (with niacinamide) which can be researched on the internet, such as Dr Saul's site doctoryourself.com or his book Fire Your Doctor, excellent advice. Everything is curable, 'just say no to drugs' (Nancy Reagan). | M | 55 | 30 days 2.5 6X day | 2/3/2011 Patient History | 4 | Psoriatic Arthritis | I have not experienced any noticable side effects as of yet | I have noticed that after the 4th dose, my symptoms of the disease began to subside slowly. | F | 49 | 7 weeks 12.5 1X W | 1/21/2011 | 4 | Skin and joints | Initially on the tablets, last 6 months via injection. I found taking the dose right before bedtime helps tremendously with side effects. Have recently got the dry mouth (always in the night) and find the folic acid helps with the tiredness. | Having dealt with this condition for 26 years its the best thing I have ever tried that works. | F | 37 | 3 years 20mg 1X day | 1/20/2011 | 4 | Psoriasis, PA | Mouth sores are not fun. I find that acitic foods help trigger them on top of MTX. I have had some consistent high liver reading, my Rhumy keeps track of that monthly. A few minor, minor PA flares, nothing like not being able to walk, or tie shoes like before. Some difficulty with memory, time and sensory perception, find it difficult to summon the right words sometimes, a problem I never used to have. Makes my Sundays (day after I take the 3 2-pill doeses) a bit slow and tired. | My Psoriasis doesn't get really red since on MTX, but it has spread. My PA is almost completely in remission, but for minor neck/back pains, elbow pains now and then. Since on MTX, I have been able to cut way back on NSAIDs I was taking (diclofenanc=bad for heart, kindneys). Doc wants me to go on Enbrel due to liver issues with MTX, but I am hesitant, due to some of the Enbrel / biologics side effects. Overall, MTX literally saved my life at a time when I was in deep dispair. I wish it worked a bit better on the skin, but for PA its been great. | M | 38 | 1.5 years 15mg 1X W | 12/28/2010 | 2 | RA | Nausea,fever,severe joint pain, dry cough/heavy chest,depression. This all happens exactly 5 days after dose. | For 4 weeks I have was taking MTX orally. Due to side effects I was given injectables. I take my 20 mg. dose on Sunday nights. I have slight nausea and fatigue Monday and Tuesday. Wednesday and Thursday are GREAT, no joint pain, nausea and fatigue much better. However, every Friday for last 5 weeks I get a low grade fever 99.9-100.7(norm for me is 97.1-97.8) I feel terrible: super sore joints, heavy chest,dry cough,fever, nausea. By Monday morning I only have the slight nausea and moderate fatigue. Then my week starts all over again. I called the Dr. today but they are closed on Fridays. I called the Pharmacist and they said this is not typical and to go to a urgent care. does anyone have any ideas?? I really wish these Dr.'s would pay more attention to people on these dangerous medications!! | M | 34 | 5 weeks 20mg 1X W | 12/10/2010 |