METHOTREXATE SODIUM Reviews (METHOTREXATE SODIUM)Average Rating: 3.3 (383 Ratings)Filter ResultsCompare METHOTREXATE SODIUM with similar:
Type: Rx Drug
|
Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on METHOTREXATE SODIUM: Reviews Summary | FDA Adverse Event Summary
| RATING | REASON | SIDE EFFECTS FOR METHOTREXATE SO | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 3 | RA | extrme tiredness, nausea lasting 4-5 days. felt ok on 10mgs but no pain relief so increased to 15mg weekly & huge increase in side effects. Experiencing vaginal thrush ??related Anyone else with this problem | F | 31 | 11 days | 2/13/2007 | 3 | Crohns | Sickness | F | 23 | 40 days | 1/30/2007 | 3 | Crohn's | Flu like symptoms, very tired for 3 or 4 days after sub-q injection, acne at times, slightloss of hair, slight loss of appetite, increase in irritability(road rage? while in a staff mtg scolded the owner of the company for whom I work). | Other drugs seemed to work for several months and then back to flare ups. I'm experiencing slight flare up now so the jury is still out. Also, my DR said I'll have to have a liver biopsy after two years of Meth injections. If Meth fails, Remicade is next(have you seen Remicade cost per year(apprx. $40,000!?). | M | 58 | 3 months | 1/30/2007 | 3 | RA | Virtually no side effects - slight fatique on day of dose. | Started taking Methotrexate 4 weeks ago (20 mg wkly for 1st 2 wks now at 25 mg wkly + folic acid + 400 mg Celebrex + prednisone 10 mg). Not noticing a big change yet although my symptoms have stabilized instead of getting worse. | F | 41 | 4 weeks | 1/30/2007 | 4 | RA | It took me a few months to build up to my 15mg dose as I suffered from nausea, tiredness, dizzyness and generally feeling unwell, but now that I am there I get very few symptoms, I also take 10mg of folic acid 3 days later, if I forget to take this a headache usually reminds me! | Although I am constantly tired, I lead a relatively normal life, which compared to my RA is brilliant. From November until the end of January I usually feel pretty crap, but as soon as spring arrives, I feel a lot better. Roll on Summer! | F | 36 | 18 months | 1/21/2007 | 3 | RA | Some hair lost but could be related to stress. Acne went away. Slight sore throat. | My RA has not displayed the tradition symptoms only 3 joints inflamed at a time in an asymmetrical pattern, right ankle, both or either knee(s) (right wrist sometimes and left middle finger). All blood levels become normal after taking the medication for 3 months(RA factor, ESR, (ANA has never been a problem)) . I still have pain, for the first 1/2 hour after waking and the occassional flare. With 600 mg of Advil daily, prescribed by my doctor, I can function walk, climb stairs, swim, dance. | F | 31 | 8 months | 12/20/2006 | 5 | Psoriasis and psoriatic arthritis. | Some nausea and strange relationship with food, which reminded me of pregnancy sickness (suddenly take revulsions to things like tea). Have quite flu like symptoms on the day after taking it. Usually go to bed on the Friday night, early - I take 15mg on Thursday night. Sickness starts Friday lunch time. Get odd bouts during the week but it's better than coping with my skin the way it was and the pain I was in. | My psoriasis disappeared like snow off a ditch at first. Was virtually clear in about six weeks. No improvement in my joints at first. Then my skin broke out again and the dose was put up. Skin improved but still have some patches but this time I had a few months of being almost totally pain free. Pains have returned a little, actually quite a lot at times but I'm not taking anywhere near the amount of pain killing medication I used to. There doesn't seem to be any rhyme nor reason to how it works. I read one patient say we are all hysterical as he/she has no side effects. Pure luck. I was also violently sick when I was pregnant - not all women are. Different people react in different ways. I have been having palpitations, which I have never had before. My Dermatologist says it's not a side effect he knows of. Anyone else experience this? Also I have very dry eyes - something else my Dermatologist has not heard of, though my optician has. These are all new things to cope | F | 50 | 1 years | 12/6/2006 | 2 | R.A | Bleeding gums, sore teeth, bloating for two days after dose, depression, headaches | Taking 17.5 mg orally, dose upped after three months from 12.5. Been on it 6 months and still major trouble with very inflamed ankle and flitting pains in other joints. Also on pregnosone 5mg but told to up in flares which have done. This may contribute to the symptoms as I have been on the two drugs together since diagnosis. My initial problem area was ankle and shoulder and latter better but may be because of cortisone injection. I would be interested in hearing from anyone whom this drug does not help and possible theories/common reasons. | F | 59 | 6 months | 12/3/2006 | 5 | rhuematoid arthritis | F | 42 | 16 months | 11/30/2006 | 3 | rheumatoid arthritis | dizzy spells,restless leg syndrome especially at night,recently had two blackouts however it's hard to define is it methotrexate or illness. Foggy memory also | started on six, took time to kick in but when it did it gave me a lot of relief from the RA. Over the years had the dose upped, now on 10 a week also take 7.5 mg prednisolone, folic acid and ibuprofen as needed | M | 46 | 10 days | 11/30/2006 | 3 | rheumatoid/ late stills disease | nausea lasting up to 3 days after taking methotrexate, vomiting same night as taking. fatigue and not feeling as if Im all there - difficult to explain, mouth ulcers, bleeding gums skin sensitivity to sun light, lack of concentration, thining of hair and headaches. | Methotrexate has been fantastic at controlling my flair ups as I never thought I would get to this stage! BUT after being on 22.5mgs for 5 years the possibility of being on methotrexate forever is daunting! I'm fed up of feeling tired, not being able to concentrate and not being all there in social situations. Starting to feel depressed by this and weighing up the pros and cons on finishing treatment. | F | 20 | 5 years | 11/15/2006 | 1 | I have systemic lupus erythematosus | hairloss, pneumonia, 57 infections while on methotrexate,liver damage.Extreme exhaustion all the time. | Took 10mg of MTX for 3 and a half years, lately told to stop immediately by rheumatoligist as my liver was having very serious problems due to MTX, let alone the rest of me, I felt so ill for the duration of being on this horrible chemotherapy drug.. | 37 | 4 years | 11/6/2006 | 1 | I have systemic lupus erythematosus | hairloss, pneumonia, 57 infections while on methotrexate,liver damage.Extreme exhaustion all the time. | Took 10mg of MTX for 3 and a half years, lately told to stop immediately by rheumatoligist as my liver was having very serious problems due to MTX, let alone the rest of me, I felt so ill for the duration of being on this horrible chemotherapy drug.. | 37 | 4 years | 11/6/2006 | 5 | psororiatic arthritus | none the arthritus started diminishing in the first week after 20 years of pain ,short term memory loss is there but as i am in my seventies this goes with the territory.after 20 years of severe pain i think M is great and i am only into my third week | it started working for me within three weeks, only time will tell what the long term situatin will be, the specialist reckons three months time i should be ok | M | 74 | 21 days | 10/9/2006 | 5 | Rheumatoid Arthritis | Mouth ulcers, bleeding gums for one or two days after taking dose, loss of concentration and memory,debilitating night sweats,bowel upsets, often severe depression. | I take 15mg once per week, together with ciclosporin 50mg caps x 2 per day, 5mg Folic acid x 2 per week. I was diagnosed in 2002 and tried other drugs which did not work.Methotrexate was initially prescribed at 10mg, and was later increased to 15mg with the addition of the ciclosporin. This worked very well and I had little pain and no inflammation. But I got scared and came off the methotrexate.Within weeks the symptoms of RA were so bad that I was in constant pain, my knees, wrists, elbows and even my jaw became inflamed.The day before my daughter's wedding I had to have steroid injections into my knee and hip to enable me to walk at her wedding.I went back onto the methotrexate asap and have had few problems since.Methotrexate is a frightening drug but RA is a devestating disease. Taking methotrexate means that in many ways I am not the person I was but I can function reasonably well.Without methotrexate the RA would mean that not only would my life be blighted, but the lives of al | F | 55 | 3 years | 10/2/2006 | 3 | Lupus | from the first dosage i got a headahe that has never went away, (its just a dull ach) and for the first month i couldnt sleep at all, from sleeping all the time to not sleeping at all, hair loss, and mood swings, and really hungry it feels like i took an incress of prednisone, but im still on the same doasage. | all and all thou its good the side effects are not so bad | F | 21 | 3 months | 9/28/2006 | 3 | Rheumatoid Arthritis | Extreme fatigue, sleepiness, brain fog. Also slight dry mouth and lips. Oh, and dysphasia... hubby said I "sounded drunk" yesterday a few hours after dosing. but, I'm only 1-1/2 days status post 3rd dose, and dose was started low and increased to full 15 mg only this week, so I'm hoping fatigue will subside by tomorrow or so. | Morning stiffness and over-all stiffness and pain do seem better so far. Not crazy about the fatigue, but I think it's better than the pain and stiffness. | F | 46 | 22 days | 9/22/2006 | 3 | Sarcoidosis | diagnosed with sarc. jan '06. symptomatic diagnosis with elevated ACE, clear chest x-ray. started on prednisone and switched over to methotrexate after a few months. i don't notice a huge change in the way i'm feeling taking methotrexate vs. prednisone; both severely reduced my symptoms (edema in legs, overall achiness, muscle weakness, tight curling/cramping of hands, joint pain), however i still don't feel "normal" (i.e. pre-sarcoid symptoms). Hard to say if current state is due to mtx. side-effects, or just original symptoms peeking through. I'm working on alternatives that will allow me to come off prescription drugs entirely... i'm looking for a solution, not a cover-up of symptoms... | M | 23 | 5 months | 8/13/2006 | 5 | Crohn's Disease | hair loss, extreme loss of energy, complete loss of appetite (no interest in food what-so-ever, even foods I normally find appealing), some nausea, general flu-type feeling | 10/mg injection taken weekly, usually given in stomach. In general, despite my loss of energy and complete loss of appetite, it has helped control my disease pretty well so far. | F | 21 | 2 months | 7/15/2006 | 5 | RA | I feel competely fatigue most of the time. This may be due to the RA. I usually feel worse day after taking it. I normally take 15mg a week. I also take 5mg of Predisone daily,200mg celebrex daily,Inbrel injection once a week, & folic acid. My mouth gets dry, may have a sore once in a while. I generally have not feeling well feeling, you know what I mean. I play golf at least 4 times a week. Without Methotrexate I couldn't do this. As I write this I have had to stop the drug, because of some lung problems. Pulmonary Fibrosis. I will be off methotrexate for 2 months & then repete test on my lungs. | Methrotrexate has done wonders for me. I was able to hold down my full time job. I still had RA flare ups, but they usually would just last a day. I did have to get off drug once because of liver test came back bad. That cleared up next test. | M | 66 | 13 years | 7/12/2006 |