METHOTREXATE SODIUM Reviews (METHOTREXATE SODIUM)Average Rating: 3.3 (383 Ratings)Filter ResultsCompare METHOTREXATE SODIUM with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on METHOTREXATE SODIUM: Reviews Summary | FDA Adverse Event Summary
| RATING | REASON | SIDE EFFECTS FOR METHOTREXATE SO | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 5 | Psoriatic arthritis | For the past 2 years limited to catching anything that goes around when i have pushed myself too hard, but in the last month I have had 2 outbreaks of unexplained rashes, and have now caught Bell's palsy virus - I am wondering if this is related to the methotrexate??? | F | 46 | 2 years | 7/9/2007 | 4 | Crohns Disease | When I first started the drug, the next day I felt absolutley dreadful, so depressed and no energy it was that bad if it had of continued I would have had to discontinue the drug, but luckily it subsided as the treatment went on.Really bad itching triggered by bathing. Exhaustion. Hair thinning. Visual Migraines.Loss of Appetite. Diarrhoea. | I do think the drug helped toward the treatment of Crohns disease when I took it alongside Infliximab, but I did end up back in hospital needing surgery and in quite a mess inside when I took it as a lone treatment. | F | 30 | 2 years | 6/27/2007 | 3 | Sojren's Sydrome secondary | Not sure if these symptoms are side effects of methotrexate. nausia,hot flushes of face,ocassional tight chest pain when breathing in and headaches.None of this ocurred before taking the drug. I also take 200mg plaquenil, 5mg prednisone daily and Folic Acid every second day. | Wanting to address fatigue. Started taking a handful of chinese wolfberries.Read some information on the berries. They improve immune system. Wondering if this may be detrimental. | F | 39 | 6 months | 6/22/2007 | 5 | Lupus | Some lower gi upset after taking it the first 2 weeks but that has subsided-thankfully! I am now up to 20 mg once a week - I have been on it almost eight weeks now. I believe I am experiencing some hair thinning as well. | The last month has been so amazingly bearable. I am finally able to get up stairs w/out pulling myself up the railing and am able to walk w/out limping and w/ only an occ. twinge of pain. Joint pain has been substantially alleviated. I feel very hopeful at this point about having a life like I had before all this muck began... | F | 36 | 8 weeks | 6/13/2007 | 5 | Dermamyositis | memory loss, very tired for the first few days | This drug has been a miracle cure and a life saver. I went from not being able to walk, sit up, and barely comb my hair, in addition to my throat muscles barely working, to almost full recovery.I started with 20mg per week but had a great deal of hair loss. I cut down to 17.5 and hair grew back. Started at 60mg per week of prednisone but now am down to 5mg.I tried cutting out prednisone but symptoms reappeared. | F | 52 | 1 days | 6/11/2007 | 1 | Ankylosing spondylitis | Felt very tired, and nauseated on 10mg/week. Developed horrific mouth sores, myelosuppression, neutropenia, and liver enzymes went way up, which led to me getting a liver biopsy. Blood counts came back to normal after 3 weeks. | Drug had absolutely no effect on my symptoms. Switched Rheumy, which put me on Enbrel, which despite minor effects, has allowed me to go back to my studies. Methotrexate is seldom effective for AS, and the risks far outweigh the benefits. | M | 22 | 2 months | 6/9/2007 | 5 | RA | None that I can tell. | It's done wonders for me! I've been taking 12.5 mg weekly along with 1,000 mg of sulfazine daily. I also take fish oil & folic acid daily. When first diagnosed in May of '06 I was on prednisone along with the other drugs. I weaned myself off the prednisone this winter & feel fine, except for minimal stiffness in hands & sometimes achy hips. Get quarterly blood tests to check for kidney & liver damage. So far so good. | F | 47 | 12 months | 5/17/2007 | 4 | RA | Brain fog, itchy eyes, weight gain - bloating difficult to deal with, extreme fatigue for two days after dose, mouth ulcers, IBS. | Methotrexate works well for my RA but I cant go any higher than 12.5mg without feeling miserable. | F | 52 | 12 months | 5/16/2007 | 1 | psoriatic arthritis + psoriasis | I hated MTX & hope never to take it again. For 6 mos, took MTX on each of 3 consecutive days per wk + Folic Acid on the other 4 days. Started with 7.5mg each day, gradually raised to 2-2-1 schedule [i.e., Day 1: 15mg (or 2 tabs)--Day 2: 15mg(2 tabs)--Day 3: 7.5mg(1 tab)], followed by gradual tapering off from MTX. Felt as if everything was leached out of me: energy, concentration, memory, my conscious being. Nausea, bone-deep lethargy, so out-of-it, I couldn't say whether pain & psoriatic symptoms reduced or not. | HMO req'd 3 mos. demonstrated failure on conventional therapy before granting me access to Enbrel. So I had to take MTX. Resultant bad liver bloods & side effects I describe here qualified me for Enbrel, but not before nearly losing my job and 1/2 year to MTX. No side effects from Enbrel, & it has abated the P & PA. | F | 56 | 6 months | 5/14/2007 | 3 | SLE (Lupus) | Nausea, dizzy/light-headed, weak, tired | Only started my first dose Wed. night of 7.5mg but felt very strange ever since. I take folic acid everyday. I just hope these side effects are normal and the drug will help my lupus. Feel free to contact me with advice etc. | F | 49 | 4 days | 5/12/2007 | 3 | Rheumatoid Arthritis | Tiredness, feeling of slowdown in the brain. I had 6 weeks at 7.5 miligrams and felt it somewhat, then tried 10 mg -- the first week I went into a fog. The doctor said go back to 7.5 for 2 weeks then try the 10 again. So I've been on 10 for 2 more weeks and feel like I've been "stunned" the first two days, less the third. | I may not be able to continue at 10 mg, but not sure of the alternatives to not taking it. Appreciate suggestions -- anyone else have these reactions? | F | 67 | 11 weeks | 4/27/2007 | 3 | RA | Am on 7.5mg once a week with folic acid two days before dose. Started to work after third dose, initially with relief next day after dose, now most of the week following dose nearly symptom free, but feeling extreme fatigue, occasional nausia,(reminds me of preganacy!) and generally off my food. The most serious side effect has been the slow onset of a feeling of hopelessness and depression. Have been on methotrexate now for 6 weeks and am going to talk to my doctor about these feelings. My RA symptoms are hugely improved, but the depression is overwhelming. | F | 51 | 6 weeks | 4/26/2007 | 5 | Psioritic Arthritis | To start with nausia and I still get fatigue and flu like symptoms 24 hours after dose. My hair thinned slightly but also went curly and blond (origionally poker straight and mousey) so not all side effects are bad. | F | 40 | 10 years | 4/6/2007 | 3 | Psoriatic Arthritis | Fatigue at first and now no real side effects (15mg once a week). I still take 75 mg of Voltaren each day for pain. I also take 1000 mg of Tylenol each night. | M | 52 | 8 months | 4/4/2007 | 3 | SLE/SOJRENS SYNDROME | I TAKE 20MG EVERY TUES BEFORE BED AND SOMTIMES IT DOES MAKE ME FEEL SICK BUT MOSTLY IF I WERE NOT ON THIS I WOULD NOW BE OUT OF WORK.SO I AM GLAD I HAVE THIS AT LEAST | IT HAS HELPED ME A LOT | F | 47 | 3 years | 3/21/2007 | 2 | Rhuematoid Arthritis | Extreme fatigue (although I found I don't get anywhere near as fatigued if I take the dose in Trexall rather than generic methotrexate), slight nausea. | I was taking Enbrel, which worked really well for a while but then stopped working, so my doctor added methotrexate. After switching from generic to Trexall, the side effects weren't as bad, but I still was in a flare up. Switched from Enbrel to Humira, still on Trexall, to see if that would work. It didn't, so I stopped Humira and just started Rituxan. I'm waiting to see if that works. Anyone out there have experience with Rituxan combined with methotrexate? | F | 50 | 2 years | 3/19/2007 | 4 | RA | Weight gain, hair damage/loss, short term memory loss, and EXTREME fatigue. Fatigue is part of RA but nothing like I've experienced on this med. I am exhausted 24/7. | The methotrexate eleviated most of the pain associated with the RA but I don't think my side effects are worth it so I'm going to seek out another avenue to deal with the RA. | F | 50 | 7 months | 3/17/2007 | 5 | Palmoplanter psoriasis | Fatigue for few days after each dose. Loss of sex drive. Some hair loss (patches) | This has been a wonder drug for me as every previous attempt to control the condition has failed. Almost complete remission of psoriasis and therefore the side effects are worthwhile. Had a recent bout of flu that lasted a month - was this extended period a side effect? My doctor thought it may be but can't be sure. | M | 48 | 1 years | 3/8/2007 | 2 | psoriatic arthritis | Started on 10mg and increased to 20mg over 2 months. Have always taken Folic Acid 800mg every day for other reasons. I take it every Wednesday night and have not noticed any notable side effects | No change in condition. Now on Remicade with the MTX and after 2 infusions of RM have only noticed a slight reduction in my baseline pain, I still have stabbing pain in all my joints | M | 48 | 5 months | 2/21/2007 | 5 | rheumatoid arthritis | tiredness,nausea and skin is itchy | i thought i would be in a wheel chair for life after wakenig up one morning and could not move or stand any one to touch or pull on me. it was a miracle drug for me. | F | 71 | 8 months | 2/15/2007 |