PLAVIX Reviews (CLOPIDOGREL BISULFATE)

Average Rating: 2.2 (612 Ratings)

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 ANTIPLATELET AGENTS

 Type: Rx Drug

  

PLAVIX  (CLOPIDOGREL BISULFATE):  Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease). It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent). Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots. It is an antiplatelet drug. It helps keep blood flowing smoothly in your body.   FDA Approval Date: 2007-09-20 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PLAVIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  mild stroke on left side after two weeks on the drug, the right side of my body has this heavy bothersome tingling sensation. I am walking like I had another storke. The right leg buckles when walking, there is pressure on the right side of my chest; so much so I have to get up from bed or from sitting. My moods are affected, speech is affected, and I have no strength on the right side of my body. M 56 1 months
6/17/2007
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 1  HEART ATTACK- 1 STENT AFTER 40 DAYS SEVERE DEPRESSION, HEAD ACHES, BRUISING, VISION LOSS, NO ENERGY,& BLOATING I HAD HEART ATTACK ON MARCH 18 AND HAD 1 STENT.I WAS STARTED ON PLAVIX. I DID OK AT FIRST AND THEN AFTER TAKING 2 DIFFERENT ANTI-DEPRESSENTS PLUS ALL OF THE OTHER MEDICATIONS I HAVE TO TAKE I BEGAN TO LOSE GROUND QUICKLY. I THOUGHT IT WAS THE ANTI-DEPRESSENTS AND QUICK TAKING THEM. I DON'T LIKE TAKING MEDICINE ANYWAY. I HAVE ALWAYS BEEN A VITAL ACTIVE WOMAN AND SUDDENLY WANTED TO DIE. I WAS HAVING DENTAL WORK DONE THIS PAST WEEK AND HAD TO GO OFF OF THE PLAVIX FOR A WEEK BEFORE BECAUSE OF THE BLEEDING PROBLEM. I FELT BETTER THAT WEEK BUT DID NOT MAKE THE CONNECTION UNTIL THE DAY AFTER THE DENTAL WORK WHEN I TOOK THE PLAVIX AND FELL RIGHT BACK INTO THE PIT OF HELL AS I CALL IT. I HAVE NOT TAKEN A PLAVIX SINCE AND WILL NEVER TAKE ANOTHER ONE AS LONG AS I LIVE. F 56 90 days
6/16/2007
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 1  post stenting after 3 weeks, each of my joints took turns, several times a day in swelling and causing incredibly debilitatiing pain, shoulder, then hip, then ankle, then knee, then wrist, then hand, then back to the joints that had previously swelled. Cardiologist sent me for xrays of hand as he thought it was broken. All swelling stopped two days after I went off plavix. may be great drug but not right for me....have just stayed on baby asprin. M 60 28 days
6/11/2007
 3  5 Bypasses, 6 stents Muscle Spasms, tingling feeling in arms and legs, nuasea. Felt good for 2 months then problems started. Doctors will not say the side effects are plavix but cannot find anything else wrong. Had additional blockage 4 months after taking plavix and 2 stents were added to the first 4. All medicated. Some days I feel good but some days lousy. More bad days lately than good. I wish they would tell me my problems were side effects so I would not worry about heart problems when I am feeling lousy. I have been admitted to the hospital twice because of my problems, and both times was told the heart was good. M 58 7 months
6/7/2007
 3  85% blockage, angioplasty, 4 stents fluid retention which I never had before taking the plavix. Sleeplessness, nausea and reflux which I had under control until taking the plavix I will continue taking it as long as my cardiologist recommends however if the symptoms increase either in severity or number I would ask if there is anything else that could be taken. F 63 7 months
6/2/2007
 2  4med stents,1 non, icd, pacer bleeding, bruises, headaches, still have many chest pains, diziness, constantly tired. am taking 2 75mg plavix a day, still not doing its job, along with toprol xl, altace, lipitor, previcid. not sure why but taking two plavix a day now and it still isnt helping, still get many blood clots. M 36 2 years
5/10/2007
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 1  As part of a research study by Mayo Experienced severe lower abdominal pain with blood in stools.After stopping,it took about two weeks to get back to regular bowel movements(No Blood!) It is my considered opinion that FDA SHOULD BAN THIS DRUG! M 71 3 months
5/1/2007
 1  As part of a research study by Mayo Experienced severe lower abdominal pain with bood in stools.After stopping,it took about two weeks to get back to regular bowel movements(No Blood!) M 71 3 months
5/1/2007
 5  Heart Attack (med. stent in LAD) Bruise easily and bleeding heals more slowly. Initially had problems with stomach bleeding, which were resolved by taking Protonix (may have been caused by ASA rather than Plavix). Now I've stopped the Protonix and don't seem to have problems. Many other side effects (Cough, dizziness & fatigue, itching, etc...) are probably due to the other medications I'm taking, but who knows? Taking 75mg/day with 81mg ASA. Also taking Coreg, Lisinopril, Niaspan, Lipitor, and Metanx. Hopefully, I can stop the Plavix at the 1 year mark, but recent studies indicate this may not be prudent, so I'll wait and see what my cardiologist says. M 35 9 months
4/10/2007
 5  5X bypass, 3 months later 2 stents Due to the plethora of other medications which also cause similar side effects as Plavix might cause, I cannot really attribute my many side effects to Plavix directly. My side effects have included low blood pressure, dizzyness, disorientation, lethargy, anxiety, depression, etc. I assume that it helped me but I cannot attribute any of the listed symptoms directly to Plavix. I am also on 81 mg of asprin. My doctor had mentioned that if for some reason I had to stop the Plavix that I would then be put on 325 mg of asprin. M 63 13 months
3/31/2007
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 3  4 stents placed 10/06 back and chest aches, brusing and bleeding if I get cut. The texture of my skin has changed- skin looks like I am elderly. Nose bleeds. Normal Cardio depression. I cycled 40miles a day not sure I could do it anymore. I take 75mg and 325 aspirin daily, I was told I would be on Plavix the rest of my life. I had chest pain and they ran the second stress test, it was clean, the drugs are just doing there thing. But I am alive. M 47 6 days
3/31/2007
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 5  1 medicated Stent RCA other then expected longer clotting time for cuts, none at all Found 80% blockage in RCA with Cardiac Cath after "unremarkable" Thalium Stress Test. Now on 75 mg Plavix, 81 mg asprin, 40 mg Zocor, 40 mg Lisonpril, and 6 fish oil caps/day. At the time Blood was 156/LDL110/ HDL25, now its 115/LDL65/HDL35. I am 210lb 6'4", in otherwise excellent shape. Nervous about Cardiologist taking me off with all the recent news. Since it has no bad effects on me, I would prefer to stay on it forever. M 54 14 months
3/19/2007
 2  heart attack - 1 med stent -1 non Pain in my chest, pain in my left side, fatigue, tiredness, insomnea, lack of energy I had cab 3 years ago, had a heart attack in Dec. They put in one med. stent and One Non- med stent I'm on Diovan, Toprol, Plavix, 1/2 asprin. I have tried all the cholesteral meds and cannot tolorate them, I feel like a old man after my heart attack. I was on topral before so im not sure why i feel this way it could be one of the other drugs, I had a stress test in feb and they said i had good blood flow to my heart, so why does my chest still feel bad? also a pain under my arm down my left side ( these are the reason I stess tested in the first place) Any one with any help? M 44 3 months
3/9/2007
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 4  Have 2 medicated stents . Bruise easily, some seem spontaneous. Bleeding from minor cuts takes longer to stop. I have taken Plavix for 14 months since two med. stents put in left artery for 90% blockage. Side effects are annoying but cardio. tells me to continue, perhaps indefinitely, because med. stent could attract a clot and lead to coronory thrombosis....something you want to avoid! Med. stents have become controversial since I had them implanted in Jan. 2006. Long term studies are not yet available to determine if Plavix must be taken indefinitely to prevent clots. Meanwhile, better safe than sorry. I notice many of the side effects described here by others(arrythmia, dizzyness, difficulty concentrating, fatigue, sleep problems) may be due to post op anxiety. I suffered from these also. I was not able to tolerate statins......tried them all. The combination of the cardio telling me I should take them combined with my intolerance of them caused a great deal of anxiety, together of course, with post op. concerns that I had a life-threatening event. Anxiety can cause all these effects. Regular exercise, yoga, meditation and an occasional xanax helped me get thru the anxiety. I am also trying statin alternatives such as fish oil, Cholest-off, dietary fiber and drastic reduction in saturated fat intake to lower chol. and LDL. Good luck and I hope this help M 64 14 months
2/27/2007
 3  2 heart attacks and a TIA Frequent nosebleeds, particularly at night. Daily headaches that began about 3 months after adding Plavix to the otheer 5 medications I take regularly. M 69 6 months
2/26/2007
 3  PFO with atrial septal aneurysm bruising, ha, anxiety ,shortness of breath I am taking plavix combined with 85mg aspirin daily. I had my PFO closure 1 year ago. For some reason my tissue has not grown over the closure device in on small area...My echo bubble study is still positive. I am now told I could have to be on Plavix the rest of my life . I am so upset. Is ther anyone out there who this has happend to?? Please help if you can. F 41 11 months
2/16/2007
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 3  Medicated Stent Nose bleeds. Two major ones in the last the last five months. Many of the complications listed on this site I have not experienced but my nose bleeds, when I get them, are terrible. Just tonight I got one and almost had to go to the hospital. I called the VA and talked to a nurse. She told me to sit or stand up and pinch my nostrels shut for 15 minutes. She stayed on the phone with me and the bleeding stopped. People taking Plavix and asprin that are having problems with nose bleeds can try this. It worked for me. M 65 5 months
2/15/2007
 4  heart attack very easy bruising, although reducing aspirin to 81 mg from reg 325 mg helped a lot. takes longer to stop bleeding, and a menstrual period where I had 12 hrs of non-stop heavy, heavy bleeding. Could be pre-menopausal hormone changes, I suppose, but I imagine it is the Plavix and aspirin combo. will continue to take it for another 6 months, only because a few people have had clots. They don't understand the mechanisms, just prescribing expensive drugs because of a few bad results. Will stop around menstrual period next month to prevent recurrance. F 49 6 months
2/7/2007
 2  medicated stent and angioplasty chest pain, right knee,calf ankle and foot swollen and extremely sore. Right eye swollen shut and tingling sensation on the right side of face. Sleeping problems. M 51 2 months
2/7/2007
 4  DES Stent in RCA after MI The only side effects I've noticed is bruising. I seem to notice that it has diminished somewhat over time. With the controversy now over drug eluding stents it's very difficult to know what the right course of action is. As I expected my cardiologist just told me I'm on it indefinetly. I'm not thrilled about it, but it seems prudent to me, until longer term studies are complete on drug eluding stents, to stay on it. M 49 12 months
1/26/2007

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