PLAVIX Reviews (CLOPIDOGREL BISULFATE)

Average Rating: 2.2 (612 Ratings)

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 ANTIPLATELET AGENTS

 Type: Rx Drug

  

PLAVIX  (CLOPIDOGREL BISULFATE):  Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease). It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent). Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots. It is an antiplatelet drug. It helps keep blood flowing smoothly in your body.   FDA Approval Date: 2007-09-20 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PLAVIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Stents Any bleeding takes forever to stop. The rest of the symptoms might be due to other meds - or medical problems. but these are the ones which came shortly after taking Plavix. These started 2 months after started: Sudden total Deafness, tinnitus, increased dizziness, vertigo, stomach pains. Are they caused by Plavix or is it a coincidence? I don't have any choice but to continue taking plavix. I have had 6 arterial stents inserted (9 mo), have had cardiac bypass (15 years), heart attack (19 years). I believe that if I would stop taking Plavix and aspirin - my chances of stroke or heart attack would be very high. Message to self: "self - shut up and take your medicine". Message received!! The fact that I'm still alive definitely raises my satisfaction level... M 67 9 months
75 mg 1X day
12/14/2010
 1  TIA I had had 5 bipass surgery on my heart in '99, and experienced a TIA about 8 yrs later. Dr. put me on Plavix and I've been on it since ( at least 3 yrs.) I've had extreme problems with bleeding during and after cancer surgery on my face, even tho I was taken off the Plavix 2 wks before the surgery. It scared the dermatologist, more than once. Since I've been back on the Plavix I've noticed an increasing weakness in my legs and pain in my knees.( which one Dr. said was a mild case of arthritis) Recently, for a surgery on my face cancer, I was off the Plavix for over 2 wks. Since going back on it, my legs have been seriously weakened, having trouble putting one foot in front of the other and the pain in my hands is debilitating. It wakes me up in the night....which, by the way is another symptom...I can't sleep and the pain in my hands is worse lying down. Now, my hand is swelling and I've had shortness of breath several times. After reading these testimonies, I can no longer take t M 82 3 years
75mg 1X day
12/8/2010
Email
 1  post stent surgery Day #2, after cerebellar artery stent implant, terrible neck,shoulder pain that remained for three weeks. Severe joint pain in virtually every joint in my body at some point or another during the three months I was on this medication. The third month I began waking in the morning to find my right hand and wrist swollen substantially and extremely painful. My hand and finger joints are still quite painful to use. Serious shortness of breath after ascending one flight of stairs, flu like symptoms, very cold fingers and toes, total lack of energy, serious loss of physical strength, loss of libido, rectal bleeding, split fingers that just would not heal, mental confusion. Prior to taking this medication I could run up and down three or four flights of stairs several times with no shortness of breath. I thought I was coming down with the flu for two months but never got it. I've lost my sense of taste and appetite. Nausea and gastrointestinal upset constantly. Total exhaustion and at the sa Thanks to all of you for taking the time to report your experiences on this site. It helps immensely to know I'm not totally losing my mind at times. M 64 90 days
75 mg 1X day
12/2/2010
 1  post MI Horrible bruising, unable to stop bleeding from small cuts for hours, rectal bleeding almost daily, blood in my urine, cold hands and feet, fatigue accompanied by insomnia, memory problems, basically just feeling terrible. Today is one of the best days of my life, it is the day my doctor FINALLY agreed to let me go off the plavix and continue to take the 325 mg. aspirin I was taking with the plavix. CAREFULLY CONSIDER ALL YOU HAVE READ HERE BEFORE YOU LET A DOCTOR PUT YOU ON THIS AWFUL DRUG. The whole time I was on it I was sure it was just a matter of time before I had a life ending brain bleed--everything else was bleeding. I just kept asking the cardiologist to guarantee me that what was happening to my hemmorhoids wasn't happening in my brain as well. She repeatedly laughed off the suggestion. Am in the process of changing doctors. F 58 19 months
75 1X day
12/2/2010
 1  MI restent after 11 years tired disoriented, nose bleed, skin bruises about the face, mental confusion,listlessness I took plavix in 1999 for 30 days I was younger and had MI with damage and stent deployed rt ventricle,ambulated fine until plavix 75mg and lipitor 10mg along with metroprolol took their toll on my overall health. I ended up in emerg with the worst 20 hr nose bleed of my life. no one paid any attention to my fears and complaint. I only took plavix for 30 days. I then started lipitor 10mg / day 4 days later I was admitted with respitory failure-the inability to produce or synthecize oxygen no solution was offered other than watchful waiting-big help that was... I asked if the drug company would be notified of this incident I was told they would not because they did not care . I am just a normal person of slight build and I have learned so much about the empowerment of knowledge..example take control of your health, you are the one in charge of this entity bestowed unto you. I don't think I will be taking drugs that give life threatening side effects that only benefit stockholders.My case is my own and I am not telling people to not take drugs or heed advice from their medical provider-but you must learn what your body tells you, you are in effect your own mentor ::: .thank-you M 58 5 days
75mg 1X day
11/15/2010
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 1  Leg vein bypass surgery My mom had a leg vein bypass surgery in march 2010 and she was prescribed Plavix, but then almost immediately she started noticing these side effects - Light-headedness, ringing in the ears and making tinnitus worse, shaky, sweats and numb all over. I didn't realize how bad the side effects could be and the potential for heart problems until recently and especially finding this site and seeing how many of you have had the same issues. My mom had a few heart problems while she was in the hospital, so it's pretty upsetting to see how dangerous this drug can actually be. I'm really thankful to this site and all of you that have submitted your stories. Thanks to reading all of this, we talked her doctor into taking her off the Plavix and now she's taking 325MG Bayer, coated tablets. I'm curious about something though. She's still experiencing some of the side effects and she's been off Plavix for 4 days. Have any of you still had side effects after stopping? I highly recommend to get 2nd and 3rd opinions on if you really NEED the Plavix, or if you can take something safer such as simply good old fashioned aspirin. I know I'd much rather worry about a simple ulcer, which can be easily remedied, rather than worry about a heart attack, stroke or worse. F 80 8 months
75MG 1X day
11/14/2010
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 2  After 6 drug-coated stents Temporary lost of memory, lost train of thoughts when talking, resulting in speech impairment at times, very embarrassing and trying to stay away from social occassion. Constant neck and shoulder pain and tightness and sleepless most nights. Can not focus on things most time. Easily bruising and bleeding due to small cuts unlike before. Have difficulty in holding on to a good firm erection as the blood flow is improved somehow. It is affecting sex life. My cardiologist prescribed after stent inplant to take 75mg Plavix and 100 mg aspirin. I had 5 stent inplant 3 1/2 years ago and I actually requested and doctor agreed for me to stop Plavix after 6 months. There is always risk of excessive bleeding in accident or medical emergency. I had the 6th stent inplant 4 months ago (after 5 stents 3 years ago)and on the same dosage of Plavix and Aspirin again and going to stop after 6 months but continue with the 100mg aspirin. Don't forget to drink plenty (up to 8 liters)of fluid preferably drinking water everyday to flush out all the drug in our body system. M 59 6 months
75 mg 1X day
10/28/2010
 1   53
1X day
10/17/2010
 2  Rule out TIA I am not sure if any of my symptoms are due to Plavix. Singificant hair loss is my primary symptom(may be from an antifungal med?). When I called my neurologist yesterday she took me off Plavix and switched me to a full dose Aspirin. She feels that I did not have a TIA. I am being treated conservatively due to a terrible (cardiovascular) family history. The Neurologist was planning to switch me to Asprin soon anyway. I also feel very anxious (like I am really over reacting internally to everything) and have a terrible pain in my neck that is not related to an injury that has caused me to wear a neck brace and have massage therapy so that I can continue functioning. The pain in my neck gets worse the more anxious I become. I am a busy highly functional professional used to multitasking but it is no longer working. I will let you know if these symptoms get better off the Plavix. Yes, hair loss can be due to stress- but what comes first the chicken or the egg? F 52 5 months
75MG 1X day
10/12/2010
 1  stents to heart I was prescribed this drug in Nov. 2009 after a TIA. Had bad side effects with a "hurt" behind the left eye, high anxiety, some shortness of breath, and an almost headache constantly on the front left side of the head. Took myself off and started taking full aspirin up to 2-3 times a day...later agreed to by my Neurologist based upon some later studies...all improved but also found out had a arterial clogging going on to the heart so had bypass surgery 3 months and but lost a couple of grafts and just had two stents also placed five days ago. The cardiologist ordered Plavix. Like a dope I started taking it the next day and have had the same worsening symptoms so will no longer take another dose of this drug. I think it is criminal that the medical pill pushing establishments doesn't followup in any meaningful way that I have ever been able to tell about side effects. While I am sure that Plavix can be successfully taken by many just can other drugs be taken by some patients and not others. But I firmly believe that this can be a very dangerous drug as well and should be monitored by prescribing doctors from the first day that it is prescribed until it is clear the patient is one that will be successful with this medication. But then that would require a doctor actually following up with a patient like they use to do when I was a kid. I am sure anyone else my age might actually remember that. Today the almighty dollar rules medicine...it's all about the numbers. It is my (your)life, better educate yourself best you can (at least these days we at least have a chance for some information). Good luck to the 1, 2, and 3s on this drug! I think you will need it. M 64 4 days
75mg 1X day
9/19/2010
 1  TIA (no after effects) Had a large spot of blood in the corner of my eye(about the size of a dime--one of the possible serious side effects) which doc. insisted I "must have rubbed by eye." It disappeared after a few days. Now have extreme pain in shoulder and hand. Very lethargic; just want to sleep. The consulting neurologist told me to just take a big aspirin a day. However, PCP had already prescribed Plavix. I'm desperate to get off this stuff, but haven't found a doc. who is willing to discuss. Anybody have any experience with weaning themselves from this drug? F 74 31 days
75 mg. 1X day
9/14/2010
Email
 2  Stoke Vivid nightmares, which I remember after I wake up, insomnia and anxiety attacks during the night. F 67 15 months
75 mg 1X day
9/13/2010
 1  stroke bruising, bleeding, confusion Please research 3-6-9 with DHA oils! anyone taking this with plavix should not be. Any fish oil will thin your blood more and cause more bleeding.. Anyone with concerns about Plavix should take a baby aspirin 81mg and fish oils for a healthier you! M 59
75 1X day
9/12/2010
 2  Steen placed after heartattack After seven months of Plavix every other day I developed sever "hives" following completion of chemotherapy. No reaction during chemo. But daily hives after chemo completed. Quit Plavix and went to 81mg aspirin. M 66 7 months
75 mg 1X O
9/10/2010
 1  medicated stent 3 weeks after starting Plavix I experienced a painful UTI that eventually cleared on its own. 3 weeks after that the finger joints of my right hand became swollen, extremely painful and totally inoperable. That also cleared on its own after 2 weeks. 3 weeks after that I woke up with a horrid boil on the lower right edge of my palm. That cleared in a week. A week later I woke up with my throat swollen shut and I could not swallow. That throat condition cleared on its own in 4 days. On the 5th day my temperature started to climb into the 102-103 degree range and the killer headaches set in. In a couple of days I was battling temperature swings up into 104-105+ degree range. I was hurting big time. My right knee started to swell up and the knee joint became hyper sensitive to any load and just locked up. I was a cripple. The knee eventually had to be drained. By this time I had been to my GP several times. My GP tested the heck out of me over several visits, prescribed several HD antibiot If you happen to be among the 7% or so of the populace that is somehow sensitive to Plavix you are pretty well screwed. If you are in the 7%, figure out a way to get off of the Plavix before it kills you. All of the Plavix allergic symptoms tend to drive all of your normally pretty good medical diagnosticians nuts. Virtually all of the Plavix allergic symptoms tend to look like other diseases, but the big clue is that there are typically no normal testable organic disease causes in evidence. All of my standard analytical disease tests keep coming back negative. In the end what you have to do is to convince your medical diagnostician to take a leap of faith with you and assume that the compendium of all of your weird medical symptoms have been caused by a Plavix allergic reaction. It is only then that you can get "fixed". The Prednisone treatment at the end of a 3 week ordeal of sickness with some serious near death overtones was pretty much magic stuff. M 65 90 days
75 mg 1X day
9/2/2010
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 1  TIA Began experiencing sharp pain in right forearm several days after starting Plavix after a TIA in 1/05 - pain then spread down to my wrist and hand/fingers and was so painful that I could not turn a doorknob, pick up a bowl by its' edge, etc. - I asked my internist about this at the one-week follow-up after my TIA and he said it had nothing to do with the Plavix (although he had no explanation for this pain) and to continue taking it! After another week, the pain had also moved all the way up to my shoulder so I called my internist who sent me to an orthopedist - after a brief exam, the orthopedist, even though acknowledging that the symptoms were NOT typical of carpal tunnel, gave me a steroid injection in my wrist! Fortunately, I went to see my psychiatrist the following week and he could see that I was not well - when I told him about what was going on, he consulted his PDR which indicated that one of the rarer side-effects was nerve pain in the extremities. So, I stopped the Plav I was so disappointed with my internist's dismissive response and tunnel vision - he never even asked about my arm when I saw him a month later. Residual effects lasted for about 8 months (puffy palms, side of my hand as well as the pinky and ring fingers were numb, and the bony area above the wrist was painful). Needless to say, I changed internists and the first thing I told my new internist was to note on my chart that I am allergic to Plavix! And the orthopedist had the nerve to send me a postcard to return for a follow-up - sorry but I already paid for an exam and useless injection and won't ever go back to a doctor who admits they are giving you treatment not indicated by the symptoms. F 61 3 weeks
1X day
8/17/2010
 2  blockage, and 2 stents hair is shedding terribly,going bald at 62 years old. Hip joint achs F 62 900 days
1X day
8/16/2010
 1  stent My husband started taking this medication after a stent was put in. He is a diaylsis patient. He has become so confused he doesn't know where he is most of the time. Short term memory is really bad. He also has severe bruising. I would definitely not recommend this for any patient on diaylsis. Will look into another medication instead. We are very disgusted with the lack of caring with most physicians. All they know how to do is prescribe medications. They don't want to hear anything about side effects. You are on your own. F 62 2 weeks
75 mg 1X day
8/8/2010
Email
 1  Stent Dizziness, lack of interest, generally feeling pretty bad. Bleed way too easily and way too much for my line of work. Only another month and I can get off this wretched med. I'll be so glad. M 30 11 months
75mg 1X day
8/4/2010
 3  stent The only thing that I can know for sure is the SHORTNESS OF BREATH or DIFFICULTY IN BREATHING. And some days seems worse than others. Seems like I have to take a deep breath once in a while. Very aggravating. I do have ANXIETY from time to time. Also not sure if related, but on occasions I have momentarily tenge pains in my head (5 second headaches) I know that may sound weird but it is true in my case. I BELIEVE THIS DRUG MAY BE GOOD FOR SOME BUT DO NOT BELIEVE IT IS GOOD FOR EVERYONE AND DON'T THINK IT SHOULD BE INSISTED IF YOU ARE EXPERIENCING BAD SIDE EFFECTS. IN SOME CASES THE SIDE EFFECTS MAY OUT-WAY THE IMPORTANCE OF THE DRUG. DO THEY WANT US TO DIE SO WE WILL BE OUT OF THE WAY? M 55 14 months
75 1X day
7/31/2010
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