PLAVIX Reviews (CLOPIDOGREL BISULFATE)

Average Rating: 2.2 (619 Ratings)

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 ANTIPLATELET AGENTS

 Type: Rx Drug

  

PLAVIX  (CLOPIDOGREL BISULFATE):  Clopidogrel is used to prevent heart attacks and strokes in persons with heart disease (recent heart attack), recent stroke, or blood circulation disease (peripheral vascular disease). It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent). Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots. It is an antiplatelet drug. It helps keep blood flowing smoothly in your body.   (Sources: U.S. Centers for Medicare Services, FDA) FDA Approval Date: 2007-09-20

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PLAVIXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  2 MI's, 5 stents easy to bruise; bleed excessively with even a small cut; occasional confusion MI Nov,2003, 1 non-medicated stent - began taking Plavix; chest pain & 1 more medicated stent May,2004 - angioplasty & radiation on 1st stent to remove and prevent scar tissue; quit taking Plavix May, 2005 for 4 days for major tooth extractions - no adverse problem and resumed taking Plavix; quit taking Plavix Jun, 2006 for 7 days for removal of all lower teeth - major bleeding within 3 hours after returning home, MI, and arythmia - 1st stent block due to radiation denuding - installed 3 more medicated stents; resumed taking Plavix and do so currently M 58 4.2 years
12/30/2007
 5  stroke somewhat burning foot and swelling hand I should be carefull about other drugs and foods which interact with plavix and increase burning my left foot and swelling my left hand which is not at good condition due to the stroke. Any drug(like omega 3 ) or eccesive amount of any fruit or spicey food(pepper,...) which increase blood thinning. M 52 6 years
12/18/2007
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 4  Swelling, Extra Heart beats, other ankles & calves swelled up a alot,forgetfulness,sleeplessness,inattetivness, extra heartbeats and sensitivity to any stimulant (ie... tea, coffea) also was very sensitive to physical changes, feelings, tempetures had a major stroke in 02, plavix helped, sleeplessness, mental clarity issues and extra heartbeat and sensivity happened in 04, swelling in 06, very expensive without insurance, considering quitting, but scared of being off it F 37 5 years
12/17/2007
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 4  2 drug eluding stents not aware of any caused by Plavis After the angioplasty I was put on Zocor, 81 mg aspirin, 10 mg Altace, 50 mg Toprol, 75 mg Plavix and Diovan. My cardiologist said the requirement of Plavix for one year was "non-negotiable". I just had a nuclear stress test, EKG and they appear fine. I took myself off Zocor (and Crestor which was given as a replacement for Zocor)after a few months and excruciating pain, cut the Altace down to 5 mg, cut the Toprol in half and the 160/12.5 Diovan into thirds. My cardiologist said that after one year on Plavix there is not sufficient data as to elimination of it. The little data shows 3 or 4 out of 1000 have a bad but catastrophic effect, so it is up to me to decide. I am starting to take 1/2 of the Plavix. I can't attribute any problems to the Plavix, but definitely to the statins--I think they are very dangerous. F 75 15 months
12/17/2007
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 5  2 STENTS AFTER ANGIOPLASTY NONE PLAVIX HAS BEEN A GREAT HELP TO ME OVER THE LAST FOUR YEARS. F 59 4 years
12/14/2007
 3  Blood Clot Headaches, I sleep a full night but wake up tired. Minor depression, and I never feel like doing anything. In a constant state of BLAH. I had a huge blood clot and am now stuck taking this for another year. My doctor won't let me switch the meds, but I imagine it's for my own good. If you can avoid this drug, do so. If you cannot avoid it, well then know what can come along with it. M 24 1 years
12/5/2007
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 2  stint implanted in coronary artery After 2 weeks on Plavix I experienced an outbreak of hives. After 3 weeks painful, crippling inflammation in nearly all of my joints. I am writing this after a sleepless night. My left arm and left knee are so sore that I won't be able to work today. My hands are also inflamed. I went back to my cardiologists office when the hives surfaced. They prescribed a steroid. I thought the joint pain was caused by the steroid, but realize after reading comments from this site that it's the Plavix that is causing it. A few days ago I reduced the dosage by 50% but no benefit. Back to the doc's office today. M 51 3 weeks
11/15/2007
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 1  blood clots Chest pain, heart palpitations, shortness of breath, dizziness, nausea, fatigue Doctors all gave me the same pharmeceutical promoted hype about how wonderful this drug is and how I need to stay on it the rest of my life. I felt the plavix was the cause of all those problems and stopped the medication. All of the problems subsided. Instead, I now take Nattokinase with much success and NO side effects!! :) Grapeseed Extract also works (in dissolving blood clots)for many people. F 45 3 months
11/15/2007
 1  heart attack miserable life. Thanks to this site for providing info i m not the only one who is facing these side effects. I stopped this medicion after one year of MI. Never ever take this. Start reading and getting knowledge. Doctors feel us stupid when we complain about side effects. Now my belive is doctors and pharmacitucals are biggest scum on the earth. M 32 1 years
11/2/2007
 5  By-pass,stents,pacemaker life Nausea,insomnia, depression,lack of desire or involvement in much of life, lethargic, diahrrea, persistant coughing,aches and pains I don't think are "normal" aging signs, weak, lightheaded and after checking all other meds I am on, I do not think what I am experiencing is because of Plavix. It is the medication I have been on the longest and these symptoms have all been over the past year or so. I think the Lord has kept me alive, and the medications today are a real hard sell for me. Plavix, has not really been the problem I don't think. I am also taking Coreg 6.25MG(newest medicine I am on), Enalapril 5MG, Zocor 5MG, and have recently with the doc's help gotten off of the anti-depressant, and sleeping pill, which didn't help me at all. I believe the Statin drugs, and even the Coreg are more than likely the real problem. I believe also that I am alive because of the Lord and that there isn't a pill for everything under the sun theses days. We would probably do just as well allowing nature to take it's course, rather than being guinnea pigs for every pharmaceutical drug that hits the market.There has to be quality of life rather than quantity. F 76 8 days
10/14/2007
 1  Possible TIA After 10 days of use lips became very swollen (3X normal size), and had trouble swallowing, both hands also swelled up, called doctor who advised go ASAP to Hospital ER. It took 2 days for swelling to subside. M 63 10 days
10/14/2007
 5  Blood Thinner None M 5 years
10/12/2007
 3  Stent I had a stent put in my 70% blocked LAD. That was the day after Labor Day 2007. This week 10/07, I could not lift my Rt Arm past my Rt. shoulder without severe pain. It started in my Rt. thigh. Then moved to my ass. It went to my Lt Thumb. Then to my Rt. Shoulder again. Then, to my Rt. Shoulder AND Lt. Thumb. Then, both Thumbs and Rt. Arm, Shoulder, and Elbow. I hate this. Do I quit my Vytorin, Plavix, Lovaza, Toprol, Prevacid, and Asprin or the Allegra and Steroids (Prednesone) I am taking for hives. News flash...DON'T GET SICK!! My Cardiologist says finish the Plavix, no leeway there. I must be on it for the full first month----non-drug coated stent. But even though he said it would give me added benefits and protection if I took it for 3-6 months, now he is saying it's ok to stop, since something is going on. I feel like a Guinea Pig. Scott F. M 43 30 days
10/4/2007
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 2  6 stents In Jan/06 I rec'd 2 coated stents and started Plavix. 8 mos later I rec'd 4 more stents and was told that I had a completely blocked artery. I was put on an aggressive medication program: blockers, inhibitors and long term nitrate. With angina still worsening I took it upon myself to stop the Plavix. I was gradually able to slowly return to an increasing exercise program. 5 mos later I stopped the nitrate and after 3 more months I am now free of any angina that I can feel. I can exercize to the limit of my physical capacity. The hitch is that I now have to live with the constant fear of fatal thrombosis due to having coated stents in me without the use of the preventive medecine. It certainly appears that in my case at least, Plavix was causing worsening Angina. I would like to hear from anyone who is having similar experience. M 66 11 months
10/1/2007
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 2  heart stent Feel tired and have pains in my chest & back. I excercise and do not seem to have chest pain associated with that activity. Feel aches like a flu most of time and tired. I don't know if this drug is causing the problems or not. Doctor tells me its a non-harmful drug so keep on taking it. I take 75mg with 325 aspirin daily. Did get off of Lipitor though. I will see if that helps. M 3 months
9/26/2007
 5  Brain-Stem Stroke None seems to allow more easier bleeding if cut M 62 5 years
9/13/2007
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 1  blood clot to heart EXTREME FATIGUE AND HEADACHE.AFTER BEING ON IT FOR 2 MONTH FOUND MYSELF FALLING ASLEEP THROUGHOUT THE DAY WITH HEADACHES. ALSO VERY VIVID DREAMS.THANKS TO THIS SITE I FIQURED OUT WHICH MEDICINE WAS CAUSING THE PROBLEMS. AFTER BEING OFF ONLY 2 DAYS BACK TO NORMAL THANK GOODNESS. DOCTORS AND PHARMIST SHOULD TELL YOU OF THE SIDE EFFECTS.I'LL TAKE MY CHANCES WITH MY LOVENOX AND ASPRIN. I WOULD RATHER HAVE SOME QUALITY OFF LIFE BESIDES SLEEPING. F 33 2 months
8/29/2007
 1  1 medicated stent Trouble breathing, for first two weeks, continued chest pain, they did another angiogram, said heart is fine, although I had been eating nitro tabs like candy and that did clear up the pain temporarily. Then put on nexium for acid reflux, I wasn't having heartburn, duh! Then send to stomach doctor, he found h pyloric bacteria and gastris. Course I knew I had h pyloric, never took all those pills to cure something that wasn't bothering me. I think it was bothering them more. I was on Toprol xl for high blood pressure, they added plavix, 325mg apririn, advicor. Talk about sick. I felt horrible. So at a month, the cardiologist's assistant changes my blood pressure med to 25mg toprol xl, add altace 5mg, lower aspirin to 81mg, keep on plavix. I started having swelling and stinging in ny hands and feet, so the cardiologist adds fluid pill HCMZ on as needed basis. My feet started hurting, and going numb, primary doc says take HCMZ fluid pill daily. Two weeks later, feet and hands s I get blurry vision, so primary sends me too Eye Specialist, eye specialist is confused as to why I'm having blurry vision, other than I've got a cataract in my right eye and one forming in left eye. But he can't explain the shooting pain in my head that comes up from just behind my ear and runs along the side of my head until it reaches the temple and then darts into the back of my eye, causing terrible pain and causing blurry vision to get much worse and not go away. Eye specialist writes new eye glass precription, but says he's sorry he can't get my right eye to focus, what's the point of spending money on new prescription for eye glasses if I still can't see right. So I am now off all meds except Plavix, which the cardiologist assistant keeps telling me I cannot stop, I will have to be on that or aspirin for the rest of my life. My feet, legs and arms have red spots now that look like bug bites, but they aren't, they are under the skin. The swelling in my feet has subsided bu F 54 84 days
8/23/2007
 1  stents/valve replacement short of breath, exhausted, bleeding Took Plavix after heart surgery, had serious nose bleeds. Stopped taking it. Had stents put in 2years ago went back on Plavix 75 mg,baby aspirin. Had stomach pain, threw up serious amount of blood, took ambulance to hospital. Found I was anemic and had ulcer. Had no idea I had a problem, just stomach discomfort. Said bleeding caused by Plavix & Aspirin. Had 2 units of blood.I'm off both Plavix & Aspirin.It's been 2 weeks and feel like I have my life back. I have more energy, attitude better, not short of breath or exhausted, can't wait to exercise. Don't care if arteries clog up at least I'll go happy. F 67 2 years
8/19/2007
 3  Heart Attack - 2 Stents in RCA I have been experiencing quite a bit of unexplained bruising. Also, I have been experiencing very restless sleep along with very bizarre dreams (which is making me quite fatigued). I think I am also suffering from mild depression, but I am not sure if that is the Plavix, or the fact that I am 35 years old and just had my 2nd heart attack approximately 3 weeks ago. These are the medications I am currently taking: 75mg Plavix 1 x a day / 50mg Lopressor (Metoprolol) 1 x a day / 20mg Lipitor 1 x a day / 81mg aspirin 1 x a day. I was already taking the Lopressor (Metoprolol), Lipitor, and Aspirin, after my 1st heart attack. The only new medication added to my medicine regimen since my 2nd heart attack, is Plavix. I have been taking Plavix for approximately 3 weeks now, and according to my doctor, will be taking it for the foreseeable future. I can only rate my satisfaction with Plavix as a 3 at this point. I have not been taking it long enough to know if it is really helping, or if I am satisfied with it. The most problematic side effect for me has been the restless sleep and bizarre dreams. I am only getting maybe 4 hours of sleep a night. I AM SO TIRED! I wake up feeling very drained, and my body feels achy. The "drained" and "achy" feelings subside throughout the day, but I still remain very tired. My 1st he M 35 3 weeks
8/4/2007

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