PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Doc says depression I say anger I went to the doc about anger issues but she told me I had depression and prescribed me pristiq. At the beginning I did notice that it surpressed my anger but when I forgot to take my tablet for three days the anger I had surpressed came back 10 fold, today out of the blue I snapped and started screaming at my partner for no reason at all I kicked holes in my bedroom door, called him every name under the sun, punched him in the chest three times and even picked up a fan and almost smashed him in the face with it before I weirdly snapped back out of it and fell into an anxiety attack almost instantaneously laying on the floor crying and breathing shallow quick breaths, my doctor did not tell me that pristiq could make me have sudden violent outbursts. I have never hit my partner before today or even destroyed anything. I am ashamed of what I've done and I hope it never happens again. F 24 3 weeks
4/19/2014
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 1  Major Depression and Anxiety I took the minimum dose and had a severe reaction to it. It was like an amphetamine in my system. Severe anxiety, insomnia, feeling burning and hot, arms tingling, a feeling of needing to shake the arms, restlessness, agitation, etc. It was really horrible. My GP told me to stop taking it immediately after this reaction. F 39
1X day
4/8/2014
 1  Depression severe At first I began to feel better, then after about 15-20 days I became glittery. I would experience loud noises going off in my head, then a jerking sensation would occurred if I got upset. About a month into the drug I began to have seizures which is a side effect, my doctor waited another three weeks to take me off pristiq, and try something else. I have been off the drug for two years and am still suffering from seizures. F 29 2 months
75 mg
3/15/2014
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 1  depression Worked for awhile, then I noticed depression sneaking back. Went from 100 mg to 50 mg. After that, I started Wellbutrrin along with the 50 mg. Went off the Pristiq. Pristiq worked for the 2 years. Went from 100 down to 50 mg., adding wellbutrin. Then went off Pristiq. This has been a rough few weeks. I have read many comments on the side effects of those going off this drug. I was relieved to hear that I was not alone. Dizzeneness, light headed, tearful. If I moved my head to quickly, the side effects were worse. Taking a migrane otc one time a day. This seems to help me. Starting week three. I am determined to get off this crap. Pristiq is much more powerful than it is portrayed. So to those of you struggling, keep in touch with your doctor, and fight through. I believe that it will be better for me to get this out of my system. F 57 3 days
50 mg 1X day
9/14/2013
 1  A lot of bad stuff happening Didn't do anything but make me sick and loose my mojo. Now being off them I still am not feeling any sexual mojo what so ever. Pristiq has ruined my sexy life with my wife. What once was 3 to 5 times a week has become 1 to 3 times a month. Your tablet is a joke and I am very pissed off about it. It should be pulled from the shelves. You put your trust in a product and cost me a fortune to be on it and its ruined something else in my life. M 30 6 months
50mg
8/21/2013
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 1  Anxiety/Depression Weight gain, grogginess, photophobia, intense tremors, diarrhea, nightmares and disturbed sleep cycle After beginning this medication I have been through nothing but hell. I have had NO positive effects even after waiting months and increasing the dosage. If you value your well-being please DO NOT take this medication! I know of NOBODY who has had positive results. Not only that, now I am stuck on it as I attempt to wean off of it. You can't break the tablets and the smallest dose is 50MG. The withdrawal symptoms are HELL and as I'm dealing with benzo withdrawal I can't quit the stuff, it's been horrible. F 25 6 months
100MG 1X day
8/13/2013
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 1  Major Depressive Disorder Severe heart palpitations/shortness of breath causing coughing; hot flashes; tiredness; severe irriability Never got a chance to see if Pristiq helped depression, since the side effects were serious enough to cause discontinuing the drug. F 56 13 days
50 1X day
7/9/2013
 1  Severe depression/anxiety OMG! I am SO tired! I stumbled across this site; I'm SO relieved to know why I've been sleeping 16 hours(and still barely able to move). I've missed work, doctors appt's, life for6 days . I'm stopping this sh**. In my experience the only anti depressant that ever worked was adderol or Wellbutrin. But you get used to those. All psychiatric drugs are crap and will fuck up your body. I'd rather be depressed than in a drunk like stupor. Do yourself a favor: happiness does not come in a pill. I've tried various stuff fir20 years. Finally learned lesson. Hey, at least it wasn't a " mood stabilizer,". But that's another story. Stay AWAY from mood drugs. Oh yeah, my headaches SO much horrible. F 39 6 days
50 mg
7/2/2013
 1  Depression Eye pressure seen ophthalmologist severe muscle tetany had to quit drug will never try new one again F 56 2 months
50mg
4/17/2013
 1  Depression Huge huge weight gain, fogginess, exhaustion, horrendous dreams you name it I had it. All it did was contribute to my depression and feelings of lack of self worth. I would not recommend this drug to my worst enemy. It is a shocker in every sense of the word. I ended up going off it "cold turkey". I just was not functioning when I absolutely had to. I have fibromyalgia so when the pain of that gets really high my serotonin levels plummet and depression sets in again so both my natural predisposition to depression and the fibromyalgia feed off each other so I need to be on anti-depressants permanently. Nothing much was working for me when I was home caring for my bed ridden dying father who I just absolutely adored. My Dr. changed my medication. He also managed to kill my father so I should not have expected he would do me any favours either. Pristiq nearly killed me as well. Just don't take it. There is plenty of other stuff out there which doesn't have the horrendous side effects of this piece of crap. F 60 1 years
1X day
4/2/2013
 1  no From a family members point of view it is like having a drunk person around you . Have to make sure they don't get up and try even walking, no sex drive, can't remember shit. M 40 6 months
1X day
2/4/2013
 1  Bipolar, depression, rapid cycling Severe and acute florid MANIC episode on this med. I do not recommend at all for Bipolar l. Be VERY wary of the noradrenergic effects! Florid dreams. Have now stopped and substituted an SSRI without the the noradrenergic effect. Make sure you are under specialist med supervision during any *changeover*! Do not take ANY alcohol with this med. From my own experience, I feel this med should be contraindicated for Bipolar_1 patients. I experienced a brief but heightened frightening manic episode on this med. Other meds i am on included: Seroquel 350mg/day, Lamictal 200mg/day, Diazepam prn.... I feel it is the noradrenergic effect that led to the acute manic episode. My later switch to an SSRI without that NA effect,namely citalopram-GA. (Celexa) helped me so much more,, as well as having a beneficial effect on my GAD. My warning is that desvenlafaxine and Bipolar 1 do not seem to agree. At least >> that's my personal experience. M 54 20 days
25 1X day
12/17/2012
 1  MDD Fever. Left shoulder n joint PAIN and left neck PAIN. From shoulder to neck. Got off meds. 1 month stiffness or Bursitis has remained. No previous or other problems. F 47 2 days
50mg
11/10/2012
 1  Depression, Bipolar 1, GAD/Panic D short-term MEMORY LAPSES/gaps/blanks (SEVERE!!) which aggravates anxiety/depression/panic attacks++. Night sweats!, reduced libido(++), intention tremor (e.g.. difficulty writing addresses on letters), depression =only mildly improved; anorexia++, florid dreams/nightmares++, early morning awakening, slight weight-gain despite anorexia. Anorexia: severe! Anergia: severe. Mood *snaps*/fluctuations: rapid cycling and mixed states. On averages, and based on my own experience, i do not recommend Pristiq for people with Bipolar 1 (depressive phase). I'm planning to taper off (am on only 50 mg every 2nd day)..It may work for some but, so far, not for me. Did not really have a noticeable pos effect on anxiety. Depression has been marginally improved.But would/will it last? I doubt it M 54 30 days
50 MG 1X day
11/6/2012
 1  Severe Depression Severe exhaustion, loss of moods (i was like a zombie), loss of memory. Took this my freshman year of college. Looking back, I have hardly any recollection of my freshman year. Bits and pieces come back to me, but it is nothing compared to the memory of my sophomore-senior years. I ended up going off it after a year. The medication was too much for me. I am on citalophram now and am doing much better! F 21 1 years
50 MG 1X day
10/8/2012
 1  Depression/Mild Anxiety first couple of weeks seemed ok, experienced some memory loss but attributed that to the Valium I had started at the same time. Now the Valium is a thing of the past, and so is my memory. I cannot remember anything! literally impossible to book an appointment and show up on time, my keys are lost, my wallet is regularly lost, remote always lost, 3 pairs of sunglasses and 3 hats lost. Some of these items show up for a day or two, then are lost again. My sex drive is zero, I have had strange episodes which have been quite hallucinatory, my vision is often shaky and now I have started getting 'zaps' also. I'm confused and feeble minded, from a normally high functioning person. I have had strange violent thoughts when waking, that I quickly forget, that make me wonder what's going on in my head while I'm sleeping. My doctor never warned me about the dependence issues associated with this drug and I'm not happy. I'm scared to come off it and not sure about how to do it. I keep booking appointments at the doctor, but missing them because my memory is so screwed. I can't cook food for my family properly any longer as I cannot properly multi-task. I even forget to pick up the kids from school! I don't know what to do with myself unless I drink strong coffee or something, anything to pull me out of this haze. This is a very dangerous substance, and I would advise extreme caution for any new users. AVOID!!! M 34 45 days
50mg 1X day
9/6/2012
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 1  Depression Dizziness, vertigo, trouble concentrating, excessive bleeding during cycle, bruising, joint pain, Worked great for about 8 months with just excessive menstrual bleeding but tolerable. Trying to go off this medication is horrible. I am on the fifth day not taking it and have had the worst dizziness/vertigo ever experienced. Driving and working feels unsafe as i feel like i am completly drunk entire day with insatiable appetite for only sweets. I had to stop taking this medication because it caused thrombocytopenia(excessive bleeding) i was coughing up blood and bleeding in excess when i got a small scrape. Be careful with this medication. F 31 14 months
100 1X day
8/11/2012
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 1  Depression I have been on Prestiq for approximately 2 years. In the beginning, the drug was doing its job and I was feeling less depressed. However as time went on, the drug would make me think weird thoughts (usually about death) and I would have blackouts. Now I've been off them for 2 weeks and feeling better in the mind- however I'm experiencing cramping, wind, constipation. If anyone has had a similar experience please send me an email.. I'd like to hear about anyone else's experience coming off them :) x F 29 2 years
50mg
8/8/2012
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 1  Depression, anxiety extreme sweating, nausea, insomnia, cloudy vision, swollen eyes, shakiness, dry eyes, extreme eye blinking I don't recommennd this to anyone unless there is no other drug on the market you haven't tried M 33 7 days
50mg 1X day
8/2/2012
 1  depression lethargy,severe nausea,sweats,insomnia,foggy head,stomach pains. Far worse than depression. F 28 3 days
50
7/18/2012

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