PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Depression; pmdd Dizziness if not taken on time; few heart palpitations I have been on this for two years and have very few side effects. Works well for me. F 43
50 1X day
3/20/2011
 4  hot flashes and anxiety No side effects but maybe some irritation, dont know.Have been on it for a year and a half.Pleased with anxiety help. My hot flashes are cut in half in intesity and duration. F 52 1 days
1X day
3/12/2011
 4  Major Depression I got brain zaps if I did not take the meds every 24 hours. It's an excellent drug with the exception that its activity is of such a short duration that I would experience side effects if I took two doses 36 hours apart (morning one day, evening the next) as opposed to 24 hours. M 50 6 months
40 1X day
2/25/2011
 4  depression When I started Pristiq, I was also taking Budeprion (smoking cessation). Maybe not such a good idea to take both. Taking both may have caused an abnormal ekg. Since I started taking the pristiq, I felt so much better, i.e. happier, stopped crying, better outlook, etc. (I have had 2 normal ekgs since) I think I want to continue the Pristiq and discontinue the Budeprion. I started feeling better almost immediately after starting the Pristiq. F 55 5 days
50mg 1X day
10/17/2010
 4  Turning into a beeoch all of a sudd Night sweats Started on 50mg, and bumped to 100 after about 6 months to take the edge off. F 49
100 mg 1X day
10/7/2010
 4  Anxiety Headache if dose is not taken on time I was on 50 for about 1.5 months and then went up to 100. After reaching my sweet spot "100" I am finally starting to level off after about a week. Helps control anxiety and panic. No sex issues at all and overall feel good. If you are on 50 and it is not working try going to 100 before stopping. It did the trick for me. M 37 3 months
100 1X day
10/1/2010
 4  Bipolar 2 This medication has kept me from my depressed cycle, where I was suicidal. At 50 mg it did not have many side effects. I had gone completely off all meds and lost 45 lbs. but5 with the 50 mg. I stopped losing. Then when we went to 100 mgs., thinking it would help with my anxiety, I actually couldn't control my hunger and gained 20 lbs and my cholesterol, which is extremely low naturally, shot up to 269. I am going back to 50 mgs., but this has been the best med for me at this time . Wish they would find something that didn't make me gain weight and struggle with high cholesterol - I feel like Alice in Wonderland! After reading the many other comments, I would have to say that everyone seems to be different and you will not know if this is for you until you try it. There aren't many choices that are healthy for people in our situation and it's a game trying to figure out which one and how much is okay. I just keep praying for a complete healing. F 42 1 years
100 1X day
9/21/2010
 4  depression At the beginning (first couple of months)- night sweats, vivid dreams After having been on it for awhile: extreme hot flashes during the day with excessive sweating, vivid dreams, inability to lose weight, no sex drive, trouble recalling words I have been taking 50 mg of Pristiq for a year with 40 mg of Celexa for depression and 3mg of Lunesta (when needed) for sleep issues. This has been the best combination for me, but it took some time to find the right dosages. My psychiatrist told me that it would take about 6-8 weeks to feel the full benefit of Pristiq, and I am glad that I stuck with it. After one year of the proper dosages/combination my doctor said that it's ok for me to taper off of the medicines because I am doing so much better. F 28 1 years
50 mg 1X day
8/2/2010
 4  Panic Disorder, Anxiety Disorder Makes me a little sleepy Was on Lexapro for a week with major anxiety and panic. Stopped it cold turkey and went to Klonopin .5x 2 a day. The Klonopin helped my anxiety and stopped my panic attacks. Then my pdoc decided to try Pristiq. I have been on it for 2 weeks gradually building up my dose to 50. I have been cutting the 50's in half and quarters to get use to the medicine. I am now on 50mg per day and it is helping me with my anxiety and panic attacks. I have backed off the Klonopin to one .5mg per day. I actually can tell when it is time for my Pristiq as I start getting a little shaky. After I take the Pristiq, I usually feel very good in about an hour or so. I wake up happy and the bad thoughts are starting to disappear from my mind. Pretty good stuff. M 36 2 weeks
50 1X day
7/24/2010
 4  depression and anxiety Breakouts of sweat I was on 50 mg for nearly a year and recently my new doctor increased it to 100 mg because I wasn't feeling any better. I am also taking 300 mg of Wellbutrin once per day. I have felt much better after the increase. I can deal with the sweats. F 34 2 months
100 mg 1X day
7/21/2010
 4  Severe Depression Anorgasmia,Apathy,and Weight gain!!! Pristiq 50mg has been wonderful at relieving my suicidal ideation and depressive mood!!! I felt relief within a week of taking the Pristiq. I also started taking Pristiq with Wellbutrin XL 300mg. I already take Abilify 10mg and Klonopin .5mg at night. I thought this was going to be my answer until I have put on 20 lbs in the past 4 months with no changes in my lifestyle except the fact that I started taking the Pristiq and Wellbutrin!!! I plan to taper off the Pristiq very soon, like taking it every other day for a week and see how I do??? Wish me luck and pray for me :-) F 40 4 months
50mg 1X day
5/30/2010
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 4  depression/anxiety Nausea first 3 days, decreased libido After 3 years of Celexa and feeling like I was living in a dense fog, I switched to Pristiq. Such a huge improvement. The side effects are minimal (and worth it!), and I feel like I can't make it through the day again. The depression is very controlled. Still having quite a bit of anxiety, but I feel like it is less severe. Hoping that with time, that will improve as well. Overall, very pleased. F 26 3 weeks
50 mg 1X day
4/29/2010
 4  Depression No side effects Works very well for me. I still have emotion but not the deep depression i had. I have used Cymbalta, Lexapro and Zoloft all of those made me a zombie. F 54 1 years
100 MG 1X day
4/17/2010
 4  Anxiety and Depression Increased tiredness. I will sometimes have day naps that last up to two hours which i don't like. Aside from this, however, no other side effects. This drug has been the best I have tried. I've also taken Paxil and Cymbalta and both of those made me extremely tired and lethargic, so this is an improvement. Has lifted my depression and my anxiety is manageable. I feel good. F 24 4 months
100 1X day
4/12/2010
 4  depression not too sure of side effects. I take pristiq with wellbutrin. Before adding pristiq I was taking paxil. I would say pristiq has a better effect then paxil. I do not have a flat affect anymore. More energy, odd dreams,generally more engaged in life and kinder. F 59 1 months
1X day
3/17/2010
 4  anxiety loss of sex drive, took care of anxiety tho. Have tingles in legs and side of head sometimes. Is that brain flashes? feel sleepy often and when I give in, it's a 2 hrs. nap. Feel like a giant pulse goes thru me when I am standing still. F 54 4 months
100 mg 1X day
3/15/2010
 4  depression and anxiety insomnia, increased energy and alertness, weightloss the initial week was very difficult, extreme stmach cramping and dizziness however after that i felt very well balanced, panic attacks had decreased and there were minimal side effects other than loss of appetite and insomnia (but i was tired). coming off the medication proved the most difficult with vomiting, mood swings and all around irretability but i found if gradually weaned myself everything was ok. uncertain if i should go back on them andhence i'm here... F 22 4 months
50 1X day
3/12/2010
 4  depression/anxiety sexual side effects, inital loss of appetite This drug is similar to Effexor. I feel much better, more even-keeled, and can laugh. No more panic attacks. However, it flattens me out a bit and does not help with motivation. I may add an ADD med for that. Biggest concern is weight gain; and though I lost weight at first, it is too early to tell about that. F 44 21 days
50 mg 1X day
2/15/2010
 4  GAD a very slight headache on day one, plus some insomnia. Take Alprazolam for sleep so that helped. Day two on this med and I actually feel happier and more positive. My headache yesterday was very minor, not bad enough to be bothersome. I already take sleep meds so the insomnia wasn't that bad either. So far those are my only side effects. F 44 2 days
1/27/2010
 4  Depression, Anxiety The most notable side effect is lack of interest in sex and difficulty orgasming. I'm only 25, and I have a gorgeous girlfriend, so it can be frustrating, not to mention difficult to explain to her. I did run out once and experienced SEVERE WITHDRAWAL EFFECTS. Apparently, this is not uncommon, and just by googling "Pristiq withdrawal" you can find many sites where other people have wrote about their withdrawal experiences. This is one of the only drugs that has helped my severe depression. I am not where I want to be with it yet, but it is better than the results (or lackthereof) that I have received with other drugs. F 25 3 months
1/27/2010
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