PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  depression/going thru a divorce I think it is keeping up at night, so I've started taking it in the mornings as opposed to at night. I feel wonderful. Haven't experienced any side effects. I'm feeling much more like myself than I have in a long time. I can say I like it. It's too early to tell of weight gain or loss. F 40 9 days
50 mg 1X day
3/26/2010
 5  depression no side effects during the course of treatment getting off of it..... WOW!! before i was taking effexor, and i had to seperate the capsules and if i took more than two beads out per week, i felt horrible. i finally after 5 months of getting off of that, started pristique. it is the same, but not as severe, but much harder to cut the dosage due to it being in tablet form. this may sound crazy, but to alieviate the brain buzz, just take psudophedrine. it cuts out the dizzy, fuzzy brain zapps!! dont know why it works, but it does!!! i just get the 12 or 24 hour dose so i dont have to take it every 4 hours.......try it!! F 44 2 years
50 mg 1X day
3/4/2010
Email
 5  major depression and anxiety loss of apetite and nausea now gone, continuing dizziness, lightheadedness, morning fogginess, difficulty focussing. constant and sometimes bad muscle/joint pain (like Ross River fever) tired and I sleep a lot . sometimes I have trouble walking -feel like a very very old crippled puppet. and Ihave dreams that are amazing (sometimes scary amazing but mostly just amazing) I have tried Prothiaden, Aurorix, Effexor(made me feel dreadful and I stopped cold turkey after 5 days), Cipramil and Lexapro etc. They (except perhaps Aurorix which was pretty good) just made me numb and eventually they all seemed to stop working. Exercise is the only thing that always helps a bit. Pristiq side effects are not particularly nice but I am (for the first time maybeever) happy. I can see thatt he sky is blue now and flowers are beautiful - I don't expect this to last but oh how easy life is now. I don't have to 'fake' being OK anymore. I am now,most of the time genuinely interested in some things. And I (yes it feels weird) really do laugh . (not the pretend one). It is a fragile thing but at least I know how easy (and wonderful) life is for those people without a black dog. (He's still there lurking in the distance- and I know he'll be back one day- he's a very persistent mongrel. But today is OK and I want to be here tomorrow and that is just wonderful. F 55 10 months
100mg 1X day
3/3/2010
 5  Depression, Anxiety, Severe Fatigue Pristiq is great but I have had side effects. The first week or two of taking pristiq were a bit difficult, nausea, dizziness, tired, runs, blurry vision (but keep in mind I was swapping anti-depressents therefore some of this would have been withdrawals as well). After 6 moths the side affects have come and gone and also changed. First few months was lack of appetite , then heaps of energy which later levelled out but I do find it hard to sleep at night. mild increased appetite, hair loss, decreased sexual drive, mild overheating, mild headaches and mild ringing in the airs. My bowels also don't move as often. Good side affect is that it has cleared up my acne which seem to be a result of stress and hormones or hormones causing stress that caused acne.... So in other words I believe the Pristiq has levelled out my hormones. I was taking luvox for a number of years and swapped to Pristiq. I wish I had done that sooner... I obviously have a fair few side affects but the side effects I have listed are fairly mild. For instance yes I find it hard to sleep of a night but I feel fine in the morning so its ok... Yes I get headaches but nothing a nurofen won't fix. I was very interested to read about the hair loss and ringing in the airs as this has just started for me even though i have been taking the drug for 6 months now.... I find that the side affects come and go such as the headaches and appetite changes. In saying all I recommend Pristiq. Pristiq has done what I need it to do and that is, feel normal again. I don't have the major symptoms, that I had as a result of depression. I don't have severe fatigue anymore, I don't have severe nausea and throwing up. I don't dwell as much, don't cry and actually enjoy life and don't have to force myself to do things. My anxiety is much better and moods are much better as well as my overall confidence in myself to cope. I was very hesitate to change from Luvox to Pristiq but I am so glad I did as Luvox was just ok where as Pristiq has really made a huge improvement to my life. I will see the doctor about my hair loss and ringing in the ears even though the ringing is mild. I also want to mention that it has cleared up my acne so much that I barely have any at all. Thats a bonus side affect for me! Pristiq is worth a try. F 30 6 months
100 1X day
2/24/2010
 5  Depression Yawning, Delayed Ejaculation, Loss of Libido Working great and effects kicked in from day 1. I'm still amazed just how much it has changed me, going from moderate/severe depression into a place where I feel inner calm. I can't thank the drug manufacturer enough. While I do have side effects I can live with them as long as it continues to make me feel happy. It's just such a big relief not to feel crap all the time. M 27 2 weeks
100 1X day
2/16/2010
 5  Depression None F 22 7 months
50mg 1X day
2/9/2010
 5  DEPRESSION, ANXIETY The first 2 weeks I noticed sexual side effects, but only a few hours after I took it. Less hungry, more thirsty. Nausea was a problem for about 2 weeks, gone now. The best thing about this medication is that all the side effects have either disappeared or leveled off for me. My anxiety is greatly curbed and depression is much less severe too. I'm able to concentrate on things better and I have more energy. My family has noticed that my temper rarely flares like it used to. Overall the results are great. F 47 3 months
11/23/2009
 5  depression/anxiety/mood swings First 3 days, i experienced , euphoria, sleepless nights, palpitations, upset stomach, blurred vision, after that, everything gradually went away, and besides some muscle soreness every now and then, this drug has pretty much turned things around for me in a very good way! M 42 14 days
11/4/2009
 5  severe depression and anxiety none Have been on Pristiq for one year now. First 50 mg, now 100 mg. Best antidepressant ever been on - have been Rx'd most of the common ones over 20 years. On Pristiq I do not get to the bottom of my depression and don't cry all the time. Feel like problems are still present, but am able to deal with them better now. Example: suffer from lonliness but am better able to cope with being with myself alone and more interest in other things. don't dwell on it so much anymore. Love Pristiq!!! F 64 12 months
10/29/2009
 5  Anxiety/a little depression Jaw tightening, sweating, decreased appetite, weight loss, slight headache,yawning. This has been a life saver for me! I've been on Celexa and Zoloft before, and Pristiq has the least side effects for me. I have actually lost weight and have way more energy! I barely ever have to take a Xanax for anxiety anymore! If it makes you tired, the trick is to take it 7 hours before you want to go to sleep. I take it at 3pm- it's perfect, good luck! F 29 3 months
10/16/2009
 5  Chronic Major Depression Decreased Libido I'm taking Pristiq 50mg, Wellbutrin XL 300mg, & Abilify 15mg. This combination is helping me to feel like normal again. Pristiq is as good or better than Effexor XR with fewer side effects. If you're just starting, give it a chance. It's worth it. M 49 1 years
10/10/2009
 5  Depression No side effects other than immediate relief. My physician initially prescribed Celexa which provided limited relief. After a "meltdown", he then prescribed Efflexor which was like a prescription to a "black hole". I now believe that hell exists on earth because this is what happened to me while taking Efflexor. After just 1 day of taking Pristiq, I actually began to feel like a human again. I've been taking Pristiq for 3 weeks now and it is truly amazing - I had forgotten what it was like to feel anything close to normal. Thank you Pristiq, for saving me. F 54 3 weeks
9/30/2009
 5  Depression, anxiety, FM, PMDD In the first 2 weeks, major night sweats, diarrhea, emotional lability, headache I am now beginning my fourth week on Pristiq 100 mg after switching from Cymbalta 120mg, which I had been on for 4 months. I was nearly out of my mind with anxiety and depression with Cymbalta, and also felt like I had a bad flu for four months with it....not good!! I can honestly say that I feel almost comletely restored to my former vibrant self with Pristiq. It's just amazing how some medications work wonders for some and do nothing for others. Cymbalta was my "drug from hell" and Pristiq is "from heaven". The depth of my gratitude that this drug is avaialble to those who know the excruciating suffering of these terrible illnesses... thank you Pristiq. I will report back if there are any changes! For those of you who haven't found the right med yet, keep trying, and try to persevere through the side effects for at least a month before you give up. My headaches, diarrhea, mood swings ALL GONE. No sexual side effects at all, in fact, my libido is great! I still sweat a lot but I figure that's nothing to put up with in exchange for peace and good quality of life. M 42 1 months
9/27/2009
 5  Depression/Nerve pain/Mood Lability None I have taken almost every antidepressant over the last twenty five years as I suffer from reaccurring bouts of moderate to severe depression. This drug has given me the fewest side effects. I am surprised by the lack of sexual side effects that seem to be the norm for these drugs and am very pleased about that! I did notice quite a big "bump" into a much more happy upswing!! If you are bipolar and not on a mood stabilizer, be careful, as always, if taking an antidepressant,you do not get manic when taking this. I think it is an awesome medication for me. As the summer turns to fall it is a trigger for me to have a downswing, so I am really hoping the Pristiq can help me hang on to the non depressed months I have so enjoyed and keep them going :). Remember you can't tell whether a drug works in a day or two-sometimes when I read these reviews I wonder what is up w/ that? Thanks so much to everyone who shares their thoughts to help others. F 45 6 months
9/17/2009
 5  Depression, anxiety, PTSD, DID, BPD Energy levels affected some. Pristiq has been a huge blesing to me. I've been on most every drug including Effexor. Zoloft was probably the drug that has worked best for me until Pristiq. I have had essentialy zero side effects on Pristiq compared with other drugs. The only possible side effect I am noticing now is a lack of energy. The first two weeks I had an increase in energy. But the past two it has seemed to drop some. I wish I could try taking slightly less than 50 mg. to see if that would help with my energy level but the pills are not supposed to be altered in any way because they are time-released. As far as mood it has helped a great deal. I also feel more balanced and my anger and frustration have significantly lessened. Many of the other drugs have caused weight gain or an increase in appetite and cravings. Pristiq has not done so, in fact I seem to be able to eat pretty much just out of true hunger and not out of emotional needs which is nice. I am very thankful for Pristiq and at least for me there has been a significant difference between Pristiq and Effexor. But one thing I am very aware of - everyone is different. What works for one person can be awful for another. You really have to find what works best for you and that is a process of trial and error. But I would say Pristiq is definitely worth a try. F 50 5 weeks
9/4/2009
 5  Bipolar Depression, GAD Headache, mild nausea, and mild sexual side effects-All in the first week. Since that first week they have passed and the only side effect I have is complete relief of Depression. It has been a miracle for me. Tried everything in the book to combat my severe lows of Bipolar II. Finally my psych gave me some samples for this stuff. I was doubtful as I had tried Effexor previously to no avail. After 6 days on Pristiq I woke up feeling like a had some years ago. I am glad to say I am now in remission. M 19 15 days
8/13/2009
 5  depression Severe diarrhea that won't stop and loss of appetite. First day took it in the evening and couldn't sleep all night. I need to take it in the morning. I have no headaches. It's really too bad that I'm probably going to have to stop taking it because the diarrhea won't stop. This is the first drug that has made me feel normal, content with my life. I love how I feel but I can't stay out of the bathroom. Even Immodium doesn't work. F 57 4 weeks
8/12/2009
 5  depression, anxiety Have been on 5 anti-depressants and none have ever worked as well as Pristiq. I feel like I think I'm supposed to feel. have experienced major sweating & headaches, but benefit outweighs that. Have to take every day @ same time, cannot miss a dose. If I miss a dose I get dizzy & nauseous & irritable. F 31 8 days
8/5/2009
 5  Anxiety Without food: Headache and nautious With food- none I started on Pristiq after being off and on anti-depressants for my depression and anxiety. I was depressed only due to post-partum, but the anxiety was constant. I always had a tight feeling in my throat and could not make it stop. All day long... Pristiq is the only drug I have found to stop the tightness, but with very little side effects. The nausia is the worst... Have noticed some hair loss (when I brush)and night sweats. Other than that, I feel better than I have in several years. Feel like I'm ME again.... I recommend this.. but really, it's all on how your own personal body accepts the med. You would have to try it to see if it would help... I wouldnt go on all the comments much.. everyone is different. F 31 4 months
7/24/2009
 5  Depression Headache, fatigue, loss of appetite. The side effects were really bad the first two weeks and then completely gone. I feel 100% better. Energy has returned and headaches are gone. F 43 10 weeks
7/20/2009

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