PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  depression rapid heartbeat, feeling dizzy/swoony. No desire for food. my dream state and waking state seem to blend - I wake from dreams and not sure they happened or I dreamed them. Was on 150mg of effexor. Now on 50mg of Pristiq for 3 weeks. The sweating side effects on effexor are gone as are sexual side effects. I've had a few instances where I get a fast heartbeat and then feel fainty/light headed. I get hungry physcially but no food really appeals to me. I think that happened in the early days of Effexor too but it went away. Energy level seems same. Still taking ambien to fall asleep every night. F 40 3 months
6/3/2009
 3  Mild depression and edginess hot flashes, some difficulty sleeping,increase in appetitite after first two weeks I had taken Lexapro and celexa for a few months many years ago and experienced a weight gain so I stopped all medication. I started taking 50 mg of Pristiq and it seemed to take effect within a few days. It really took the edge off and put me on a more even keel. But that only lasted a few weeks I suppose I got used to the dose and the positive effects just dissipated and I started to gain weight -even though I work out 6 days a week. I really don't understand why these medications make you gain weight. At the end of the day the weight gain really adds to my low self esteem F 51 2 months
4/21/2009
 3  Depression nausea, jaw clenching, severe insomnia Was on Zoloft for 2 years. That was awfull. Pristiq seems to have worked already. however still cant sleep. Im willing to give it a bit of time. F 26 3 weeks
3/17/2009
 3  Depression and Anxiety I experienced headaches, anxiety and some depression I have been on pristig for over 3 months. I was on effexor XR on 112.5 mg for over 3 years for depression and anxiety. At the end of 2007 I was feeling great so my doc. and I decided to begin reducing the dosage. 2 months later I relapsed. Changed pdoc and was given Cymbalta, did not work, and now on Pristiq. I feel somehow better but still having some episodes of depression and anxiety. I was also prescribed lamictal to control the downs, which seems to work ok. I will report in a couple of months to see if there is any improvement. Effexor was an amazing drug for my condition. M 36 3 months
1/22/2009
 3  Severe depression A bit of anxiety In regard to sexual side effects, everyone has sex, knows what it is, and there's a whole lot more to life than whether you have good sex or not, such as being not depressed. I would hope that people have evolved to the point where living a productive and satisfying life means infinitely more than a good lay. Jesus christ. Grow up. F 48 4 days
1/21/2009
 3  Depression Yawning constantly. Always felt as if I had a very dry "lump" in my throat. I have a high-stress life parenting two very special needs children. Pristiq truly helped me feel more calm and not as "down" on extremely stressful days. But as a singer, I could not tolerate the dry, lump in the throat feeling. F 39 3 weeks
11/19/2008
 3  depression, binge eating excessive yawning but not sleepy, clinching jaw, slight teeth grinding but not noticeable. small bouts of energy on and off throughout the day took 2bc powders for headache on 2nd day and appetite returned. i guess the bc powders overturned the pristiq. but day 1 and 3 little to no appetite. not sure if i'm hungry or not. can not finish a complete meal. over half the meal still left over. once took welbutrin for depression, didn't work at all. mother passed away unexpectantly 7 months ago and having a hard time getting over. i read 8 chapters of psychology homework in 1 day, was never able to do this. unable to orgasm. F 30 4 days
11/3/2008
 3  depression reved up F 44 60 days
10/5/2008
 3  Depression Headache, drowsiness I was only able to take it for a day before it turned out my doctor was worried about the possibility of Pristiq causing my blood pressure to become too high. Treated me much better then Lexapro did, though! F 24 1 days
9/2/2008
 4  Depression/anxiety symptoms Really not much serious. The doctor did raise my high blood pressure medication because Pristiq raised it. Maybe some anxiety the first few weeks but then that stopped and I actually feel that Pristiq helps my anxiety long-term. I have chronic fatigue due to atypical depression. I am tired a lot, have somatic pain, and apathy. I've found that Pristiq is great for energy. Actually I discovered that because, if I miss a dose or two, I become very drowsy. I just can't get out of bed. Then I take the Pristiq and within 4 hours I feel brand-new! So I guess I'm kind of stuck taking this drug now LOL. I tried to use fluoxetine (Prozac) to ease myself off of the Pristiq, but the withdrawal and fatigue are just terrible. I'm going to stay taking the Pristiq. M 38 6 months
100 mg
7/21/2021
Email
 4  Menopausal depression A little jittery at first and my ears felt stuffy like I had a cold. I have tried quite a few antidepressants and these side effects are pretty mild. I was feeling low and having symptoms like PMS every day. Taking estrogen has not helped , I think because it's such a low dose . Pristiq is a good medication for depression that makes you feel slow, heavy and tired . It hasn't made me anxious. I have read some comments about withdrawals coming off this and other antidepressants. Your doctor can prescribe some medication to take for a short period of time to help with those symptoms. It really helped me getting off some migraine medication which had terrible withdrawals. One is Clonidine and the other is Hydroxyzine. I'm sure there are others , too. F 57 45 days
50 mg 1X day
3/13/2021
 4  Depression and anxiety Only side affect i have is constipation. Which is something i usually have no issue with. I do feel a great difference. Feeling better but hoping this constipation goes away with time. Anyone else have issue with this and what did you do to help? F 45 8 days
50mg 1X day
12/27/2020
Email
 4  GAD Panic Disorder Moderate loss of libido. Excessive sweating. Slight weight gain. Occasionally forgetfulness. SNRI that worked the best for me and still feels effective to some extent after 7 years. M 25 7 years
100 1X day
12/10/2020
 4  Clinical depression Constant heartburn Came off it for a few days and withdrawal symptoms were terrible F 74 10 years
100 MG 1X day
11/29/2020
Email
 4  Depression Has anyone had an affair on their husband after taking this drug? Oddly, I have 2 friends going through a breakup after MANY YEARS together and both women just switched to Pristique. This is not normal behavior for them. Wondering if this is happening to others??? F 53 1 years
50 MG 1X day
10/20/2020
Email
 4  PMDD Reduced sexual desire, yawning, tiredness. Pristiq has helped lift my chronic depression before and during menstruation. It has improved my relationship and I have not had suicidal thoughts since taking it. I don't experience overwhelming sadness and hopelessness anymore. I don't feel emotionally numb however, I think since the cloud has been lifted I am feeling love towards my family more. I have lost 4kgs as I am not binge eating also. F 28 30 days
50 MG
6/20/2020
 4  anxiety I've had no side effects, I tried going off one time after about 3 days I was feeling sad and weird then remembered Id quit my Pristiq. So went back on and feel good I've tried Wellbutrin, effexir, busipar, and others with no notice F 52 3 years
50
3/7/2020
 4  Major depressive disorder I was taking it for several years at 50 mg at first and then bumped up to a hundred milligrams. After my mom died I went up to 150 and then to 200. Once I got up to 200 I experienced significant brain fog and cognitive decline. I have weaned off and tried trintellix to which I had an allergic reaction with much itching and then viibryd which I could only take for two days. I may go back to pristiq if my psychiatrist suggests it. I did have weight gain. It has some sexual side effects but not horrible. I might ask if I could go back on pristiq and supplement it with something else. Pristiq was really amazing for me for many years. Worked well for me for many years in the 50 and 100 milligram dosages. F 48 4 years
200 mg
1/12/2020
Email
 4  depression disorder anxiety disorde No significant side effects. dry mouth I went from zoloft (because of side effects like insomnia and worst anxiety) to Pristiq F 37 3 months
50
8/10/2019
Email
 4  General anxiety disorder and adhd No significantly serious dude effects when compared to benefits, but for some reason I've developed some crazy amount of fatigue. Trying to stick to medication to see if it's something else first, as ok initially. Overall, the benefits have been remarkable and it was odd that despite expecting a long time to ramp up as advised I noticed difference with days, not weeks that was positive. M 51 3 months
50ng
5/24/2019

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