PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Satisfaction lowest to highest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  depression Reduced libido When I am on this drug, I feel great, and occasionally I even skip a day, but if I skip more than a day, I spiral down almost immediately. This drug has worked wonders for me. I consider it much better than Paxil, which really zonked me out. M 69 6 years
50 1X day
2/22/2017
 4  Major Depressive Disorder First few days felt drowsy, dry mouth. immediate lessening of anxiety and improvement in mood and ability to control emotions. My body has a history of gradually requiring more dosage over years. Was on Effexor, Ciprimil before they didn't work anymore. I enjoy a good quality of life thanks to Pristiq. F 46 6 years
400 1X day
2/13/2017
 4  Server depression/anxiety Low libido, forgetfulness. Brain zaps, light headed and headaches, nausea, if I miss a dose. I started with 50mgs the Doctor put the dosage up once the symptoms eased to 100mgs. Each year on the effectiveness would wear off so up another 50mgs till I was on 200mgs. Spent the last year on 150mgs starting to wean off. Last month on 100mgs with feeling agitated, mood swings headaches & the last few days I have spent crying from emotional meltdowns. Didn't make it to work today. Had to talk to anyone about what I am trying to do when it makes me burst into tears. Not to mention keeping my depression secret from people outside a small amount of close family and friends. Wondering how I can get this done with out having to explain it to my daughter's (10 & 8) F 46 6 years
200mg
2/6/2017
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 4  Depression I have noticed no side effects, UNLESS a recent shakiness I developed is connected to the Pristiq. I am better on Pristiq than I was on Zoloft, but I'm still suffering from some depression. F 53 1 years
50 mg 1X day
9/5/2016
Email
 4  Depression When on 50mg, lots of nausea and dizziness. Irritability. On 100mg I have night sweats and don't sleep well, sweating has become much more common during the day. Nausea if I don't have it with a full proper meal. Some loss of appetite (not necessarily a bad thing). Decreased sex drive; happy to have sex and enjoy it but not interested in instigating. This pill has worked really well for me, my brother takes it as well and has also had success. Obviously, not for everyone but has worked well for me. Most symptoms are manageable. F 31 10 months
100mg
3/9/2016
 4  Chronic depression Only side effects for me were constipation and difficulty sleeping. Changed diet and added Trazadone for sleep I have had chronic depression for years ( 25 at least ). Started on Prozac, went to Lexapro, then others that I can't remember their names. I was put on Pristiq when it first came out. I started with 100MG then down to 50 MG. BEST drug for me. I am now 67 and have weaned myself off the drug completely. Now that was a real challenge! F 67
50 MG 1X day
6/20/2015
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 4  Depression, Anxiety Weight loss I have tried many antidepressants over 28 years, and Pristiq is among the most effective for me. No matter what I take, however, I still experience some depression and anxiety; it is likely that no medication will completely eliminate my symptoms. Pristiq does allow me to function relatively normally, and I am grateful for that. I do supplement Pristiq with Seroquel (quetiapine) 25 mg for sleep. Otherwise I would have extreme difficulty falling asleep. I have experienced very low libido over many years, and Pristiq does not seem to have affected this one way or the other. F 72 2 years
100 mg 1X day
6/4/2015
 4  depression anxiety bad thoughts Nausea, headache, nervous I have tried many antidepressants over the past couple years & had allergic reactions to all of them. Most putting me into the hosputal. With pristiq I have been able to concentrate & have more energy to be motivated to get up & do my normal routine. I was so nervous because I was so exhausted with the side effects that I didn't want to try a new medication again. But once I got over the fear, I feel much better so far. Not euphoric but, able to go about my day without so much worry & anxiety. Medicine doesn't cure everything but, I have learned many coping mechanisma to help as well. I hope my insight has helped. I have ocd tendencies & now I am not trying to be so perfect besides a few things since I am a mother. Before I was unable to have enough energy to keep up with my 2 year old. Now I can & hope that I can get back to normal, if there is such a thing. Just don't give up. F 28 6 days
2/3/2015
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 4  depression/anxiety While taking medication: itchy skin, constipation, jaw clenching, slightly foggy brain sometimes, and no sex drive. When I miss a dose: whenever I miss 1 day, I get a bad headache, nausea, crying for no reason and dizziness. When I had to miss 2 days due to prescription problems, I had all of that except my dizziness and vertigo were extremely bad! I didn't feel safe driving and every time I moved I was so dizzy I felt like I might fall over. Overall when I take my medicine I feel great! It has definitely helped with my depression and anxiety. However, when I don't take it, I feel like crap! I am honestly scared for when I do decide to stop using this medicine because I know that the withdrawal will be the worst. I am looking at others' responses to see different ways that people got off of pristiq to see ways to help with the withdrawal side effects. Definitely do not go cold turkey! F 22 2 months
50 mg
1/30/2015
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 4  Depression anxiety The pill has helped with my depression if I miss one dose within 24 hours I'm so dizzy headed and lightheaded I can't function I have a headache. And my depression is just awful crying for no reason. I have absolutely no sex drive. After saying all that I was so depressed I was on the verge of suicide it's help with that. F 39 10 months
50mg
1/9/2015
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 4  depression vivid dreams and loss of appetite F 39 2 weeks
50mg
4/24/2014
 4  Feeling down and flat The first few days were like I was on crack or something couldn't sleep, hardly ate and felt sick but after a week I feel perky, laughing more and now something I never would have guessed i'd become a morning person (not everyday but big improvement). But most of all instead of taking moods out on my partner iv become the one who addresses problems more calmly. Woot woot! F 23 2 months
50mg
4/2/2014
 4  Depression, Stress butterflies in tummy, reduced appetite The drug seems to be working really good.. My wife has said that I am more in control of stressful situations and my mood has become less prone to extremes. I have noticed that I am not reaching for an extra piece of pizza and I am getting these 'extreme butterflies' in my tummy, as if I am about to do a speech in front of a large crowd or about to reach the top of a roller-coaster.. sometimes it can feel a bit much, but I imagine it will calm down. I am on this stuff for 6 months and week two people are noticing improvements, so Im happy :) M 32 10 days
50mg 1X day
3/7/2014
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 4  Anxiety Brain fog every day about noon, lasts for 1-2 hours. Forgetfullness. Was having major anxiety including panic attacks. The pristiq worker wonders for the anxiety. Side effects are a concern but controlling my anxiety is more important. Plan on staying on the drug for 4-6 months than weaning off. M 51 30 days
50 mg 1X day
1/30/2014
 4  Depression/anxiety Hair loss, weight loss, flat affect after while Overall this was not a bad drug for me..I lost weight (22 lb) but the hair loss became noticeable and my moods flattened out after about 7 months. I went off of it only because the price was so high after the Pristiq discount stopped - even after insurance my copay was just too high. One thing to know about any drug like this is for the first few days/weeks you are going to feel a little bad - it's manageable. As far as dose - start low - it's better to go up then try to come down. If you decide you want to stop the medication I suggest asking your doctor to give you a week or so of Prozac to help. F 46 9 months
50 mg 1X day
6/25/2013
 4  Anxiety, Depression The first 2 weeks were hell. I threw up the first 2 nights and was having alot of trouble sleeping. My mind was racing, i was nauseous and unable to concentrate. I had the jitters and was very shaky all the time. I would sweat so badly at night my pillow was soaked and i had to get a towel. I began locking my jaw while i slept which caused migraines and alot of pain. My sex drive does not exist any more. Most of these symptoms went away accept the locked jaw lasted a few months, i still sweat at night but not as bad, and my sex drive is still dead. My new side effect is exhaustion. The last few months i have only ever wanted to sleep. Despite all the bad side effects, which mostly went away, this drug has been a life saver. After about a month of taking it i remember walking my dog on a sunny morning and actually feeling happy again. It was amazing. It took another month or 2 for the depression to finally lift. I still have a ways to go and the recent exhaustion is hard on me, but it lifted the depression enough for me to be able to get back to my life and make changes to help myself. F 27 5 months
50 MG 1X day
3/27/2013
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 4  Depression and Anxiety Have been on low dose Pristiq for 2 years, in combination with Concerta for ADHD. In past 6 months, have been dealing with stiff neck, painful and numbing headaches and feeling like I have strep throat without the typical pain of strep (more like a lump in my throat). Am very tired. Sharing this because I see other folks have referenced identical symptoms. I'm definitely going to my MD with this. F 43 2 years
30 mg 1X day
3/16/2013
 4  Sever Depression/Mood instability Calmness, Mild insomnia, Slow gradual weight loss (bonus!), Feeling of being Antsy. High energy (bonus!),... Swollen throat, slight tremors in hands. I've read online that the swollen throat (which feels similar to having "Strep Throat" without the pain), should subside on it's own within a week. No sexual side effects. M 36 4 days
50 mg 1X day
1/28/2013
Email
 4  anxiety and depression While starting Pristiq I had some head aches, low sex drive,and some body/muscle twitching when relaxed and trying to fall asleep. All of those side effects have since disappeared and I am so glad now that I hung in their and stayed the course. I feel like myself again and seems to be better than being on Paxil for 15 years. M 47 6 weeks
100 MG 1X day
1/25/2013
 4  Depression and anxiety Definitely helps steady my moods but there are scary side effects while drinking alcohol. These include black outs, memory loss, acting out of character, dropping to ground without cause, blurred vision and slurred speech. I've always thought that it was just me being drunk, but now I'm certain it's the combination of this drug and alcohol that does it. F 31 6 years
50
1/1/2013

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