ZETIA Reviews (EZETIMIBE)

Average Rating: 1.4 (601 Ratings)

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 HYPERLIPIDEMIA

 Type: Rx Drug

  

ZETIA  (EZETIMIBE):  Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates). Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Reducing cholesterol may help prevent strokes and heart attacks.   FDA Approval Date: 2002-10-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZETIACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  high cholesterol Severe muscle pain, especially in my thighs and upper arms, and generalized weakness after taking the drug for 5 months. Increasing difficulty walking and going from sitting to standing. Pain somewhat improved after stopping Zetia 2 weeks ago. The drug did lower my cholesterol quickly and dramatically, but the side effects are terrible. When the pain begins, it's easy to think it is just age-related, but it quickly progressed to being severe and lifestyle-altering. F 53 5 months
11/28/2006
 1  lower cholesterol pain in neck glands and in shoulder. The neck glands were sore and would spasm when I laid down, bent over or sat up. Discontinued use and pain went away - started it again and had to stop taking it entirely F 53 3 weeks
8/14/2006
 1  high cholesterol and triglycerides h.pylori, severe ribcage pain on left side dizziness, headaches tired all the time, shoulder pain headaches joint pain THIS IS A TERRIBLE DRUG AND MIXED WITH A STATIN IS HORRENDOUS, I TOOK MYSELF OFF OF LIPITOR THIS WEEK AND ZETIA NEXT WEEK, HAVE STARTED COQ10, FOLIC ACID COD LIVER OIL, B6 AND B12, I DON'T SUGGEST ANYONE USE ANY OF THIS CRAP. ZETIA WAS ONLY TESTED FOR 9 WEEKS BEFORE IT WAS PRESENTED TO THE DR.S F 53 1 years
12/11/2006
 1  high cholesterol Occasional pressure in ears (like changing altitude), weakness & heaviness in limbs. Also sensitive to Vytorin F 53 3 days
7/5/2006
 1  To lower triglycerides Unable to take statins. After 7 days on Zetia noticed a lump in the right side of my throat (lymph nodes swelling). Increased sinus problems, but with this being the spring season just thought it was allergies. on the 8 day I started having a tingling sensation in my upper lip which increased through out my face. This was very uncomfortable as it felt like hundreds of pinpricks in your skin. Developed blisters along the inside of my upper lip. I just felt very tired. I also experienced severe sharp pains in the back upper left tooth area almost like I may be having an abscess. This pain also increased throughout my teeth and gums. Very painful. I have RA and have been on Remicaid infusions for the past ten years. Due to this drug I have become allergic to a lot of drugs however I believe the Remicaid is what caused my triglycerides to exceed to 800(+). My MD tried me on statins and I had severe lower back pain to the point I had to get my husband to help me out of bed. So my MD put me on Zetia as she explained it was not a statin and have never had a patient yet who could not take it. Then I'm her first. What good is a drug if it deplete your quality of life. I am looking for a drug free way to lower my triglyceride levels. F 53 7 days
4/1/2017
 1  Further lowering Cholesterol Severe headaches Chest pain Arm pain Severe breast tenderness I had similar problems with Lipitor and am currently on the lowest dose of Crestor with no issues. My numbers are great but I just had my second stent installed in my lad and it freaked out my dr. He was shocked that I had developed more blockages so fast (first stent was 3 years ago). Put me on zetia to get my cholesterol as low as possible. The chest pain was bad and would actually wake me up at night. The Brest pain was excruciating. I'm off the drug. Symptoms are mostly gone... Not sure what else to take bc I currently have another blockage of 85% in a non dominant vessel in my heart. F 53 5 days
10
4/17/2017
 1  To control my cholesterol Absurd headheache,chest pain Sharp pinches in my left arm And whistles in my ears.. And adding icing sugar on the cake My blood pressure was scary to read.horrible medication.. Stop it asap if you take it .. I rather have cramps in my legs with crestor and cope with it. Zetia is a killer med. M 53 6 days
10 mg
2/28/2018
 1  To lower cholesterol Horrible bloating, gas, sulfur burbs, nausea, severe stomach cramps, diarrhea, sinus issues, sore throat. Stopped taking 5 days ago, no relief. There has to be a better answer than to be this miserable. Messaged the cardiologist as it was over the holidays, no reply. DO Not Take this medicine. Request something different. Just not worth feeling this bad everyday. F 53 30 days
10 mg
1/3/2019
Email
 1  had heart attack and high cholestra Very gradually and insidiously my body started to break down, first with a stiff neck making it hard for me to turn my head. Next came a sever shoulder pain - so bad that I had to quit working out in the gym. Next I developed what I thought was carpol tunnel syndrome so bad I had to wear a wrist brace. Next came "tennis elbow" that got to the point where I couldn't even bend my elbow to brush my teeth. During all of this I would wake up with horrible soreness in my back which I just learned to live with and accepted as a result of "growing older". It never occured to me that I was much too young to be feeling this out of sorts day and night (I'm 53). I've always been in excellent physical shape - working out at the gym 5 days a week, treadmill every morning and tennis weekends. I never had any of these problems until I started statins Advcor and Zetia. I was fine at first but after about a year they built up a toxicity and began poisoning my body. It wasn't until I It's so easy for a doctor to just prescribe a pill and then move on to the next patient that's waiting in an adjacent room. You know your body better than anyone else. Be proactive. If you want to lower your cholestal do it the old fashioned way - change your diet and preferably go vegetarian as there is NO cholestral in plant products. Take charge. M 53 2 days
8/11/2008
 1  HIGH TRIGLYCERIDES I HAVE RA AND THOUGHT THAT MY SUDDEN DECLINE IN MY HEALTH WAS DUE TO THE RA BUT I HAVE NOW FIGURED OUT THAT IT WAS ZETIA, NOT RA. MY RIGHT EYELID STARTING TWITCHING AND FEELING "LAZY" AND MY VISION WOULD BE SO BLURRY SOME DAYS THAT I COULD BARELY SEE TO WORK. SOME NIGHTS I WOULD BARELY BE ABLE TO SLEEP. FOUR HOURS IS NOT ENOUGH FOR ME. MY NECK MUSCLES HAVE BEEN HURTING SO MUCH THAT I CAN BARELY STAND TO SIT AT MY DESK SOME DAYS. LOTS MORE HEADACHES THAN USUAL....JUST A GENERAL FEELING OF MALAISE. I HAVE BEEN OFF ZETIA FOR A WEEK AND AM FEELING SO MUCH BETTER. THANK GOODNESS I FINALLY FIGURED OUT THE PROBLEM!!!! I WILL NEVER TAKE THIS STUFF AGAIN. F 53 2 months
12/14/2009
 1  High cholesterol Severe chest pain, severe arm pain, couldn't get out of bed for 2 weeks, diherra so severe I dehydrated, labs were all over the place, couldn't urinate. Was hospitalized 5 times while doctors tried to figure out why I was so sick. They thought I was dying and didn't know why, and so did I. Ran out of meds within 3 days of stopping it I has fine. I have no doubt if I would have continued this drug I would have died. DO NOT TAKE THIS DRUG F 53 60 days
10mg
11/29/2017
Email
 1  Cholesterol I was on Whelchol, it brought down my cholesterol from 280 to 157. But the pills were hard to swallow. My doc switched me to Zetia to maintain that huge drop. After 10 MONTHS ON ZETIA, I HAD LABS ON 1/28/8 AND MY CHOLESTEROL LEVEL IS NOW 244!!! I AM SO DISAPPOINTED!! I HAVE NEVER MISSED I DOSAGE OF ZETIA AND IT DID NOTHING BUT TAKE MY MONEY 10 MONTHS OF THIS DRUG AND MY CHOLESTROL WENT FROM 157 TO 244! F 53 10 months
2/2/2008
Email
 1  High Triglycerides Horrible drug for me. Nausea, bloating, flatulence, heartburn, belching, loss of appetite and diarrhea and sleepless nights. Couldn't bear to last more than 2 days on this drug. It's been two days since I took my last dose & I'm still not back to normal. I'd rather go full on vegan to control my high chol. and triglycerides than be sick from a drug. Lesson learned. I need to get back on track and do better for myself. F 53 2 days
10 mg 1X day
12/15/2022
 2  Lower genetic high cholesterol Headaches and nausea. Increased appetite and cravings. I didn't even take Zetia daily. I started with every other day and after a few doses I had to stop. I have FH and I'm on Repatha and a low dose statin. My doc wanted me to take Zetia as well. It was awful. I had rolling headaches and waves of nausea throughout each day (even the days I didn't take it and in general felt ill and kind of depressed. I've been off it now for 5 days and today was the first day I kind of feel like myself. Another strange side effect has been an increased appetite and food cravings. I haven't seen reports of that. Then again, maybe all the nausea triggered the cravings. I suspect since this drug acts in the small intestine that possible it messed with my gut biome which threw off my appetite controls. F 52 1 weeks
10 mg 1X day
7/26/2021
 2  high cholesterol I can not take statins because of severe side-effects. My doctor gave me a one month prescription of Zetia to try. I don't know yet whether it is actually helping my cholestrol, but I have been experiencing some side effects. I take it in the evening as recommended because that is when your body manufacturers cholestrol (and the pharmacist said fiber can interfere with the absorption of Zetia) However, every morning, I get nauseous right after eating breakfast. I also have been experiencing some joint pain (I have arthritis already, so the joint pain got worse after starting Zetia) and muscle aches, fatigue and now I seem to be starting to itch around my abdomen and the back of my neck burns. I would like to find something I could take to help my high cholestrol because of our family history of heart disease, but sadly, it doesn't look like it will be Zetia. Has anyone ever tried taking Niacin for high cholestrol? I heard that can work but it can have side effects similar to statins..... F 52 3 weeks
10 mg
10/3/2013
Email
 1  Elevated HDL Sore throat and extreme nausea with constipation. After discontinuing, lips started cracking and bleeding. Developed sores on knuckles of right hand. Continued nausea and constipation. Feel so sick I can barely go to work. Will be so glad when this poison is out of my system. F 52 10 days
10 mg
9/27/2012
 1  lowering my cholesterol pain every where and weakness along with headache.. I have enough problems(MS) and then to add this on top of them, please!!! F 52 30 days
10 mg 1X day
5/22/2010
Email
 1  for Hyperlipidemia Severe bloating, muscle pain, loose stools, severe pain in elbows My Dr. put me on Lipitor for 6 months. I felt like crap. I was going to my chiropractor because I hurt so much. Severe pain in back. Heard commercial on TV of side effects and called my doctor and he switched me to Zetia. No difference, even worse symptoms. Im going to stop and see what happens. F 52 1 months
8/21/2007
 1  high cholestrol I ache all over and have muscle cramps. Sometimes my left hand just cramps up and during the night I get charlie-horses in my legs. I am taking 10mg and my liver count went from 37 to 114..this is hurting my liver. F 52 6 days
4/15/2007
 1  high cholestrol I ache all over and have muscle cramps. Sometimes my left hand just cramps up and during the night I get charlie-horses in my legs. I am taking 10mg and my liver count went from 37 to 114..this is hurting my liver. F 52 6 months
4/15/2007

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