ZETIA Reviews (EZETIMIBE)

Average Rating: 1.4 (601 Ratings)

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 Type: Rx Drug

  

ZETIA  (EZETIMIBE):  Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates). Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Reducing cholesterol may help prevent strokes and heart attacks.   FDA Approval Date: 2002-10-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZETIACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  For high blood pressure After taking for four days started having pain in both knees when trying to exercise or climbing stairs. Also had pain in both shoulders and calves. I could not tolerate statins before taking Zetia, but my doctor put me on this saying I should have no problems because this Is not a statin.i got the exact same symptoms on Zetia that I had on Crestor. I am quitting this drug after taking it for one week, will never take this again! M 62 8 days
10mg
1/13/2015
 1  high cholesterol burning feet, have to take shoes off and put feet up. Skin rash on left side of neck and chin, a bit like sand paper. Overall arthritic pains. F 62 2 months
7/4/2009
 1  To lower my cholesterol Horrible muscle and joint pain. Pain so severe that I had difficulty walking. I had a fear of walking, or even walking a short distance. I thought I had kidney stones, and some other disease or health issue. A CAT scan and MRI ruled out all of my suspcions. Then a friend told that she had to stop her cholestrol medicine because of all the side effects...Bingo. I started my own research, then I decided to stop the Zetia. So far my pain is greatly reduced and I can tell that I am improving after just a few days off of Zetia. This is a horrible drug and the doctors won't admit it. I really believe doctors get some sort of monetary stipend when they give patients scripts for drugs they know will cause side effects. My advice...STAY AWAY FROM THIS DRUG. While on Zetia, I thought that I was losing my mind. I could not stay focused,depression set in. I could not find a reason why I was depressed, unhappy, moody, irritable and felt somewhat sucidal rather than tolerate the pain. I would always be appreciative of my friend who told me about her experience with her cholestrol medication. I felt like I was 100 years old. I am now back exercising and I now enjoy, once again, being almost back to my old self again F 62 2 days
4/29/2009
 1  cholesterol Excrutiating pain in shoulder got so bad I could not raise my arm above shoulder level, within a few weeks after starting this drug, Then I started experiencing depression, and confusion. I blamed the pain on my age, but when I became depressed and I couldn't think straight, and felt like my brain was full of cobwebs, I came to this website, and after reading of similar symptoms, I decided to stop taking the zetia. Within a week symptoms lessened, and were totally gone in 2. THANK YOU F 62 4 months
4/20/2009
 1  to lower cholesterol all over aching, especially in chest, back. head feeling swollen like it was going to explode, all over muscle tightness, overwhelming fatigue yet could not sleep, mood instability, rapid and irregular heartbeat, heat surges. 4 days off of zetia and symptoms are abating. tried zetia because didn't tolerate pravachol for similar, yet not as severe, side effects. this was actually a frightening experience as i usually feel quite normal and healthy. F 62 18 days
8/21/2009
 1  marginally high cholesterol After forcing me to try Lipitor, Crestor, other statins (tachecardia after 3-7 days), My doctor put me on Lipitor with NO warnings. 5 weeks later, I collapsed due to weak muscles and was locked in a psych ward for depression due to this drug. It took me 5 days and $500 for an attorney to get me out. My doctor (and the doctors in the emergency room) did not recognize depression as a side effect of Zetia, refused my request for a referral to a psychologist (I didn't know what it was), and by various unrelated comments, my doctor got me locked up. Needless to say, it was a hideous experience. This all happened before the advertising blitz about the "rare but serious side effect" so I had no idea what was causing my symptoms. My doctor is one at a huge senior community and she "forces" everyone onto these cholesterol drugs, and despite another visit, did not recognize the side effect symptoms. This drug took 1 year out of my life, extensive muscle biopsies, and I'm only now recovering 75% of the energy and movement I had before 5 weeks on this drug. F 62 5 days
10/1/2009
 1  High Cholesterol Muscle pain in legs, feet thighs, upper arms and hands. Cramping in extremities. Joint pain hands and wrists. Numbness and tingling all over. Severe sore throat and dry nose. Have been on Zetia for a little over 2 yrs as I do not tolerate statins. One year ago started with vague muscle cramping in legs and feet and would wake me up. Then started with the tingling sensations all over, felt as if I was shaking, but had not visible tremors. Dry throat, nose and eyes. Called cardiologist, was told that if this were due to Zetia side effects are usually seen within a couple of months. Also talked to my internist who thought this was all anxiety related. She also said do not stop this medication unless I wanted to have a stroke! Have just started care with a new physician. Now a year later I have finally stopped this medication on my own. Liver functions are a bit high as well as glucose. Severe dry throat has improved, not totally resolved but definitely improved within 2 weeks of stopping Zetia. The cramping in legs, feet hands and arms have improved after being off this medication for 5 weeks. Also numbness and tingling improved. Will give this several more months to see how I am feeling. Can't imagine restarting this medication and absolutely do not recommend it. F 62 2 years
10mg 1X day
7/8/2020
 1  High cholesterol With statins I had elevated CK and muscle pain, my doctor switched me to Zetia. I took it for 9 days and started with the same symptoms. However symptoms are almost worse now that I've been off it for 72 hours. Weakness, sweating, muscle pain, joint pain. I can hardly make a fist. Climbing stairs is an effort. I'm done! I just hope this goes away! Never take it. F 62 10 days
10 mg 1X day
7/12/2015
 1  high cholesterol i had heart burns, diarrhea, stomach pains, muscle and joint pains, breasts spasms, ended up going to a breast specialist, headaches, panic attack, thought i was having heart attack, almost went to the emergency room, insomnia, palpitations, severe weakness, hives, back pains, bloating, gas, aches and pains all over the body. zetia is poison to the body, it's scary. patients who took it should be compensated for pain and suffering. i want to know how long my body gets rid of its the side effects F 62 6 days
10mg
3/27/2015
 1  High Cholestrol Dizziness, muscle pain, chest pain, stomach pain, lower back pain. At times breathing problems. Extremely tired and fatigued much of the time. My wife and I could not understand why, but then we remembered the doctor put me on this drug a week ago. Had problems with other statins with muscle pain, but nothing like this. I stopped taking the drug today! M 62 10 days
10/5/2008
 1  high cholesterol and high LDL I had fibromyalgia pains. Dizzy spells especially in the am. Neck spams, lower back spasms,terrible hip pain, arthritis in hips, lower back pain. Pain in the intercostal muscles between my ribs. Shortness of breath. Weakness and no get up and go any more. I would not take any cholesterol lowering medications if my life depended on it. I cannot tolerate all of these drugs F 62 6 months
7/23/2007
Email
 1  cholesterol Muscle pain in left arm, left shoulder blade and neck. Also have erection issues Started taking Zetia due to muscle pain, etc from Zocor. Two years into it, I am having the same side effects. Even though my cholesterol is controlled, the side effects aren't worth it. M 62 2 years
5/24/2007
 1  high cholesterol Increased joint pains increased lethargy diarrhea intermittently sinus congestion and increased mucousproduction. Stopped taking for 5 days cannot believe the difference thank god for finding his site thanks F 62 6 months
10mg
5/15/2012
 1  high cholesterol Increased joint pains increased lethargy diarrhea intermittently sinus congestion and increased mucousproduction. Stopped taking for 5 days cannot believe the difference thank god for finding his site thanks F 62 6 months
10mg
5/15/2012
 1  to lower my cholesterol Severe stomach pains, soles of feet so tender that I could not walk. Severe muscle pain in shoulders and arms. Leg pain was severe. Headaches. Chest pain. I. DO NOT RECOMMEND THIS DRUG. Have not had a normal bowel movement since taking this drug. Have to go thru a colonoscopy and endoscopy to see what damage it has caused. F 62 3 months
15mg
3/20/2012
 1  high LDL After about 1 month of starting the drug I began having charly horse type pain in my calves, both at night & during the day. Sometimes I would awaken 2 to 3 times a night and couldn't get back to sleep. I also have had sinus pain & diahrea for the past 10 days. A few days ago I developed a rash on my face & decided to call my doctor. He advised that I stop taking Zetia for a few weeks to see if the symptoms clear up. I've had similiar reactions taking statins. F 62 7 weeks
10 mg 1X day
2/18/2011
 1  High Cholesterol The side affects were sooooooo horrible when taking Crestor that I am not even considering trying Zetia. I wanted to cut my legs off @ the knees the pain was so acute. I almost lost my job because I didn't realize what was happening to me. I was even vomiting plain water when I could even keep[ it down. If any one out there were happy with Zetia after experiencing severe side effects with Crestor....please let me know. F 62 0 days
10mg 1X day
9/6/2010
Email
 1  Joint/Muscle Pain Back pain (muscle cramping), pain in the thumb joint (where the thumb meets the hand, thigh pain radiating to the calves, knee pain. Had so much joint pain on lipitor that the doctor decided to put me on crestor and zetia. Terrible joint/muscle pains. Went back to the doctor and decided to keep me on zetia alone. Just as bad. 5 days and I could not believe the amount of pain. Could only lay in bed, unable even to roll over or lay on my side because of the pressure that position put on my thights and knees. Never - never again will I take any chlosteral-lowering medication. Began low-fat diet and hopefully will be able to exercise again. F 62 5 days
10 1X day
2/22/2010
 1  lower LDL After about 1 month I have developed nightly extreme leg cramps, these I also developed with Zocor but it took about 6 months. Did not take it long enough to test for lowering cholesterol M 62 30 days
10/14/2006
Email
 1  high cholesterol Hand cramps (which I've never had in my life), severe shoulder pain left side like my muscle seizing up, very tired, brain fog/forgetting names I know - all in 2 days. Won't continue. F 62 2 days
10 1X day
12/24/2023
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