ZETIA Reviews (EZETIMIBE)

Average Rating: 1.4 (601 Ratings)

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 Type: Rx Drug

  

ZETIA  (EZETIMIBE):  Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates). Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Reducing cholesterol may help prevent strokes and heart attacks.   FDA Approval Date: 2002-10-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZETIACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  high lcd severe joint pain was also taking nexium. it has the same side effects. decided to stop taking both meds. F 60 2 months
2/9/2008
 2  high cholesterol Have a problem with statins, and I also am taking zoloft for depression. Had a really bad bout of depression and stomach problems on both previous statins. Put on Zetia. Gradually feeling more and more depressed, tired, and gas discomfort. I do not want to go through what I experienced twice before. Glad I decided to do some research before I thought I was loosing my mind. The question is - what can I take? M 60 25 days
10mg 1X day
2/24/2013
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 2  to keep cholesterol under 180 After reading all these comments, I am scard now. I have trouble breathing and taking a deep breath. I feel like crap and have muscles pains and now3 knots are coming out under the skin near elbows. I am on 5mg Zetia and have been for about 6 months. Byr Bye, Zetia. I hate Chi\Olesterol lowering drugs. M 60 180 days
3/23/2007
 2  Cannot tolerate statins Extreme fatigue, memory loss, sleepiness. I thought this was being caused by beta blockers but when I stopped them, the symptoms persisted. I'm also on Questran but when I was taking that alone, I had no adverse symptoms. That left Zetia as the culprit but my doctor refuses to recognize that it could be causing these things. In any case, I stopped taking it in September and in about 10-12 days my energy returned and I feel much sharper mentally. It was as if a curtain had been lifted. I did not make the decision to drop zetia until I read the comments on this site. Zetia did produce marginal results for me when taken in conjunction with Questran and Niaspan. However, the side effects were too great. It may be useful for some. Everyone is different. Since I cannot tolerate statins, I'll rely on Questran and Niaspan for the time being. M 60 3 years
12/6/2007
 2  High Triglcerides It caused me problems with my nerves.I felt like I couldn't stop the feeling of jumping out of my skin. F 60 1 months
1/3/2008
 2  ELEVATED TRIGLYCERIDES/CHOLESTEROL HEADACHE, NAUSEA,ABDOMINAL BLOATING, WEIGHT LOSS THEN GAIN,PAIN IN UPPER ABDOMEN, DIZZINESS WEAK MUSCLES AND FATIGUE. I HAVE CONCERNS ABOUT ANY DRUG BUT THIS ONE HAS BEEN BOTHERING ME ALOT LATELY. FIRST I HAD UNEXPLAINED WEIGHT LOSS AND NOW 4 YRS LATER WEIGHT GAIN. IF SOMETHING IS "TOO GOOD TO BE TRUE" IT PROBABLY ISN'T SAFE LONGTERM. IT DID REDUCE MY LEVELS HOWEVER. WANT TO STOP BUT IS IT SAFE TO 'COLD TURKEY?" WANT SOMETHING MORE NATURAL I THINK! THANKS! F 60 4 years
5/26/2007
 2  Cholesterol Neck and shoulder ache started in third week along with fatigue. I've tried Crestor, Lipitor, Vytorin and now Zetia. I've had the same results with each one. I took Crestor for three months and the side effects started in the second month. I continued another month hoping the side effects would improve or go away with time. I was so exhausted the third month I decided it was crazy to continue taking it. It was the same story with Lipitor and Vytorin only I quit when the side effects started knowing they wouldn't go away. I'm not sure my doctor can find a medication for me. F 60 3 days
10/8/2007
 1  high cholesterol Pain, cramping, heaviness in thighs, calves. Joint pain in hands, elbows, etc. Have always been active with exercising, but having difficulty now. Stopped Zetia three weeks ago, and I am only somewhat better. Hope none of this is permanent. I'm devastated by this. See the MD this week. Let's see what he says. I just can't go on this drug again and definitely none of the statins because Lipitor did a number on me with muscle pain throughout my whole body although after going off of it it took about 6-8 mos. to feel right again. I am still taking Omacor (prescription omega 3 and omega 6) which the MD had prescribed along with the Zetia. F 60 9 months
8/4/2007
 1  to lower Cholesterol I have been on Zetia since June. I've been getting muscle pain and joint pain in my rotator cuff and left shoulder and muscle pain in my back. Now my other shoulder is starting to hurt. I was going to go to an orthopedic doctor, but I think it is the Zetia. I feel terrible and achey. I am stopping this lousey medication as of tomorrow, December 1, 2007. The statin drugs did the same thing--I tried three different brands. I'm going to try red rice yeast and garlic tablets. F 60 5 months
11/30/2007
 1  Cholesterol Severe abdominal pain, gas, and bloating. M 60 5 months
11/30/2007
 1  cholestrol Muscle pain, pain in hips. Fatigue, terrible weight gain. Would not recommend. Wonder if anyone else noticed a big weight gain. F 60 6 days
5/14/2007
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 1  High Cholesteral Muscle aches with Lipitor; double vision with Zocor now Zetia has caused extreme pain in shoulders; depression, headaches; and worse fatigue ever experienced. I have been taking it about 6 months, quit two days ago and feel better already. Read the literature and more inportantly, monitor yourself! Dr. told me it was safer than statins. I must be overly sensitive but this is NOT the answer for me. I will try diet (rarely eat meat) and exercise...now that I have some energy back! F 60 6 months
6/27/2007
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 1  high cholesterol lower back pain; joint soreness; chest pain; gas; nasal congestion; headache; eyeache or pressure on eyes; frequent bowel movements After reading all of the other comments that support my sense that this drug has caused several side effects, I am stopping this medication today and will maintain my diet, exercise and CoQ10. I appreciate everyone's comments. M 60 7 days
7/2/2007
 1  cholestrol. simvastat and liptoroff I was taking lipitor for app two years came off and was given simvastatin had calve pain . I started the Zetia and for the last month discovered severe toe pain and knee pain in both knees for a month. I read the comments today and saw that I share some of the common side effects. This was helpful I will notified my doctor this week but I will need to come off. I am having a difficult time climbing my stairs in the home. I have no major health problems with my my knee joint that's why I have to take my self off of this medicine. I'm not sure if the sudden burning around my neck and brake out of redness on my body. his is not often but it just started a week ago It sometimes feel like a mosquitoe bite. After taking the medicine at night i have been having pains in the chest area but i sit up for about an hour or drink something warm before going to bed. I may stop taking tonight after reading some comments and inform my doctor that i have done this My next appointment with him is not until June 27. I had blood work completed two weeks ago but i have not heard from him. F 60 3 months
10mg 1X day
5/6/2013
 1  To push bad Chlor below 70 Took 1 pill on Tuesday morning. Triggered vertigo & vomiting attack Wednesday morning. Felt bad Thursday and Friday. OK by Saturday. I will live with 90 -> 100 bad cholesterol and risk my artery blockages getting larger. I tried Zetia, but will not take again. M 60 1 days
10 1X day
6/27/2010
 1  high cholesterol It took me a week of gradual symptoms to wake up this morning thinking "maybe it the Zetia". I still don't know but I'm stopping the medication to see what happens. My most pronounced symptom was dizziness and insomnia. Today I had a really bad stomach and ageneral feeling of unwellness. After reading these comments I can add to this list things I was just avoiding recognizing: itching, aching breasts????, sinus issues, a feeling like there is a rock in the center of my body. I also began to think there was really something terrible going on with me. It was scary. Not sure if this is the reason for it all....the Zetia.....but I bet it is. F 60 14 days
1X day
2/4/2011
 1   Had been taking Zetia since 2001 because Zocor caused me sever and morbid depression. Then in 2006, Zetia was prescribed in combination with Fenofibrate 145 to improve my numbers further. However, in April 2008, my doctor reversed her decision about the combination because of concern that Zetia is not recommended to be taken with other drugs. However, she reversed herself again in October 2008 when my overall numbers increased over 200. Throughout the time I was taking Zetia I started taking massive cortizone injections in my knee to take care of what I thought was the onset of severe arthritis. Then my shoulders caved and I thought I had severe bursitis. Never did I suspect that Zetia might be at the root cause of these pains. By the time I was taken off Zetia in April, I had sever pain in neck, shoulders, knees, hips, and feet. Then, the miracle. Throughout the summer of 2008 I started feeling better, exercising more rigorously, and found myself pain free by autumn. Woohooo! I remember just before my father died that I had intense arguments with his several specialists, none of whom could track what the other one was prescribing. They just aimed from the hip and fired at whatever symptom my father was presenting. Frankly, some of the symptoms were caused by reactions to other drugs. It was then, watching my father weaken every day until his eventual death that I determined to be the master of my own destiny. In the case of Zetia (and Zocor and other statins for that matter) I have all the information I need. They are not for me. Despite their marginal effect on reducing cholesterol, they have to be viewed in the context of one's own life...and if the quality of life is lacking, then the "clinical" yippee that we get out of lower cholesterol numbers has to be confronted. I have made up my mind. The pain and lack of life quality is not worth it. Finally, I continue to be outraged by the pharmaceuticals' resistance to full disclosure about M 60 7 years
11/10/2008
 1  cholesterol I had severe depression and all my joints ached it became hard to walk just several yards. The depression had me near suicidal and the joints aching kept me from doing anything much.I had muscle aches too, I just haven't discovered which were from the medicine. Just daily chores became too much. I felt as old and I thought it was me until I stopped the pills. Two days and I was depression free and started to feel so much better physically. It was like taking 10 years or so off my age. I feel human again. I would never recommend this drug and I am beginning to doubt that lowering cholesterol is a good idea or we would feel better on these drugs instead of worse than before. Hormone replacement was a bad idea for what 20 or 30 years and this may be another bad idea that they will discover in 20 years. F 60 60 days
4/6/2009
 1  To lower LDL Loss of appetite, severe congestion in the sinuses which has now moved to my chest and I now have a severe cough. I had only been on Zetia for 3 days when the congestion started. It took 11 more days of suffering for me to figure out that it was the Zetia. I am having a horrible time remembering words I want to use when I am talking. I quit taking Zetia yesterday and the congestion in my head is starting to clear, but the cough has yet to subside. I have tried Crestor and Zocor. Both caused horrible depression. I would rather risk heart attack or stroke than not be able to get out of bed in the morning. I would not recommend this drug or any of the other cholesterol lowering drugs. They are poison. I had managed to lower my LDL from 296 to 276 in 6 months without drugs. I'll keep doing what I'm doing naturally, watching what I eat and exercising. The drug companies can keep their poisons. F 60 14 days
4/24/2009
 1  to lower cholesterol First afternoon after taking one pill I took a nap and woke up twice feeling panic and paralyzed all over. Have had uncontrollable bouts with loose stools. Husband says I have acquired a slurred speech pattern. Also dizzy and sometime have this strang "zing" feeling go through my head/brain. Was on Simvastation after rt carotid artery endarectomy and it greatly affected my thought processes. Also recently diagnosed with diabetes and have had peripheral neuropathy for 1 1/2 years. My last Zetia pill was taken yesterday, and I mean the last. F 60 3 days
6/28/2009
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