ZETIA Reviews (EZETIMIBE)

Average Rating: 1.4 (601 Ratings)

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 HYPERLIPIDEMIA

 Type: Rx Drug

  

ZETIA  (EZETIMIBE):  Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates). Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Reducing cholesterol may help prevent strokes and heart attacks.   FDA Approval Date: 2002-10-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31


RATING  REASONSIDE EFFECTS FOR ZETIACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  cholesterol reduction NONE. Was taking simvastatin at 20mg/day. Needed to reduce LDL further and went to 40mg/day - but no additional effect. Went back to 20 mg of simvastatin but added 10 mg/day of Zetia and was able to meet my LDL target within a month. Liver tests all normal. M 61 120 days
11/27/2007
 4  High Cholesterol Mostly gas. For a while I was having muscle aches. I don't know if they were from the Zetia or from exercising at Cardio Rehab (had bypass surgery in Jan). Zetia definitely got my cholesterol down but I have more gas than a Saudi Prince. I was originally having muscle pains but started taking CoQ10 (100 mg from Wal Mart) and the pains quit. Still got the gas though and GasX doesn't touch it. I'm going back to natural red rice yeast to see if that fixes it and the cholesterol stays down. M 61 4 months
5/31/2007
 3  high cholestrol After taking this medication for 2 months, my overall cholestrol had dropped 60 points and my LDL was down 55 points. The medication did it's job, however, it's not without side effects for me, and I'm not sure whether I think it's worth continuing to take it. After taking it for 2 1/2 months, the corners of my mouth were dry and cracked and my lips got so chapped that I had to put bag balm on them 24 hrs a day. Also, my tongue began to burn whenever I brushed my teeth. I could not gargle with mouthwash for more than a second or two. I also was experiencing a feeling of a lump in my throat. I have not seen anyone on this site who complained of a burning tongue but I did read someone's side effect of the lump in the throat. I stopped taking the medication 10 days ago. My lips are considerably better and the toothpaste no longer burns my tongue. The other person said it took 5 weeks for the feeling in his throat to disappear so it's a waiting game, however, it does seem to be som F 61 3 months
12/3/2008
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 2  to lower cholesteral I took Zetia for almost two years. It reduced my cholesteral from 305 to 225. I felt fine for about six months, but gradually experienced severe leg cramping, then persistent back ache, then general aches and pains EVERYWHERE in both muscles and joints. The last three months on Zetia I became EXTREMELY weak in my legs, stomach muscles and back muscles. I was all bent over and couldn't stand up straight. I struggled to stay awake, struggled to go up and down stairs and sometimes even take a walk. I also had major heartburn and heart palpitations. Why did I not stop taking it? I asked my provider to do a CPK test to see if there was a problem and she said they do that only when you're in the hospital. Duh? I had taken 10 mg. of Lipitor and got the same symptoms in a very short timeframe (13 days), so my provider switched me to Zetia, saying this would not cause the same symptoms. The symptoms were more insidious than on Lipitor. I took Zetia close to two years, struggling with weakness and pain the last three or four months. Because of the nature of the symptoms, I simply thought I was getting old and had arthritis or something. In fact, I injured my knee while I was taking Zetia, had surgery, had great difficulty recovering full strength or full use of my knee, and now realize some of these problems were probably due to Zetia. Now that I have stopped taking it, my knees don't hurt at all and my back does not ache! P.S. I'm a physician's wife, so my experiences were a real eye-opener to him. F 61 2 years
3/3/2008
Email
 2  Cholesterol ldl 99 I take it at night with Lipitor middle of night I would get stomach pain, my bpm dropped to during day 40-45, I feel so tired during day, will stop taking it as of today@ M 61 1 months
20 1X day
9/3/2020
 2  zocor made me have hip pain i started on zetia a week ago and already i am haveing joint pain in hands, elbows, hips and legs. will keep on trying for another week, but it this pain continues will stop. F 61 7 days
3/25/2007
 2  to lower cholesterol same bad shoulder pain as I had while taking Lipitor, had to discontinue stopped taking it after 39 days because shoulder pain was too much, interferred with sleep F 61 39 days
5/20/2006
 2  high cholesterol stomach pains with gas It worked very well to control my cholesterol (lowered my overall from 255 to 191 and raised my HDL!) that I was very reluctant to admit that it was causing me problems. I was unable to sleep for 4-6 hours after taking it at bedtime, so I switched to a morning dose instead. Then I was unable to work effectively bacause the stomach pains became so bad. Sadly, I have had to stop it completely. F 61 90 days
1X day
1/22/2013
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 2  high cholesterol Mild stomach pain. Bloating, gas and frequent bowel movements. Occasional extreme right hip pain. Pain between shoulder blades. Occasional shooting pain in right middle finger where it joins my hand. Fatigue. After finding this site I was somewhat relieved to see that so many other people had similar symptoms as me. I exercise at least 4 days a week and I noticed I have not been able to improve my performance. I will stop taking med today and keep a daily record of results, if any. If symptoms disappear I will make another posting at this site. ( I have tried statins but they cause extreme fatigue and muscle pain.) Zetia did reduce my Cholesterol from 205 to 157. Although I rated this drugs effectiveness as 2; in all fairnes,I still don't know if it is the cause of the symptoms. M 61 8 months
11/12/2007
 1  HIGH CHOLESTEROL BACK PAIN , UPPER AND LOWER , WEAKNESS , TIRED GENERAL MUSCLE SORENESS, FLUID RETENTION IN ANKLES,,,,,,,, ON ZETIA FOR OVER A YEAR , JUST CAN'T TAKE THE MUSCLE PAIN ANYMORE , IT DID LOWER MY CHOLESTEROL ABOUT 35 POINTS BUT AT A TERRIBLE COST TO MY WELL BEING...... M 61 15 months
9/15/2007
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 1  high cholesterol Severe abdominal cramping,bloating, and night sweat.Also experienced shoulder pain. This medication had adverse side efffects which occured very qiuckly.I believe more long term research is necessary regarding this med. It is being prescribed without reservation and may show serious side effects over the long haul. M 61 2 weeks
1/16/2008
 1  High Cholestoral Loss of energy, depression, lethargy, pressure in chest, pain on left side, headaches, dizziness, lack of sex drive, headaches Due to extreme muscle weakening while taking Lipitor, my doctor switched me to Zetia. I experienced several weeks where I had no quality of life. I am of slim build, eat very healthy and exercise. We are researching famiial hypercholesterol and ways to treat that. Zetia is not an option. M 61 3 months
3/3/2007
 1  High Cholesterol Extreme dizziness and not thinking well. I started it as the same time I started another med (for blood pressure), so I stopped the Zetia and dizziness went away within 3 days. 1 1/2 yrs later, I tried again, determined to get past the side effect. I took it for several months and the dizziness did not subside. Since I teach at a college, this was a problem, not being able to stand and teach without dizziness and having some problems remembering what I needed to say next. I stopped taking it on Friday, and by my first class on Monday, I felt like I was able to teach again. Dizziness was gone and my thinking was returning to normal. I had great hopes for this, since I could not tolerate statins at all, though I tried several times with different ones and different doses. F 61 90 days
10/18/2006
 1  To lower cholesterol 4 days now Diarrhea. Stomach cramps. Sharp pain in left abdominal quadrant. Just an over dull gut feeling and blood when I wiped .Stool was food that was undigested M 61 6 days
10 MG 1X day
12/7/2021
 1  Cholesterol Shortness of breath, dizziness, constant hunger, hair loss,panic attacks Was prescribed this medication in addition to Crestor after having a stent inserted due to chest pain. Trusted my Doctor to prescribe proper meds. I have spent the last decade dealing with dizziness and shortness of breath to the point of being admitted to the hospital for tests which always were fine. Figured it must be the combination of all my meds causing these complaints. About a year ago my insurance had issues with paying for Zetia and in the meantime I ran out...did not take zetia for about a week. EVERY symptom disappeared!! No longer short of breath, no longer dizzy, no longer hungry, hair came back thicker and no anxiety issues. Started taking flax seed oil instead and cholesterol is at an all time low. Horrible horrible drug!!! Someone should be held accountable for it's release to the public. M 61 9 years
20MG 1X day
1/9/2016
 1  Lower Cholesterol Kaleidoscope of pain in my chest all over that would come and go. Worst was my torso felt like someone beat me up. Constant bruised feeling. Only took half a tablet daily. Can't imagine what would have happened if on full dose. Nurse practitioner said my side effects were unusual. Really? F 61 2 weeks
30 1X day
3/5/2018
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 1  high cholesterofl Since taking Vytorin, I have had 3 bouts of diverticulitis, which I never had previously--colonoscopy in 2006 was fine. Now I have muscle/joint pain starting in left hip, then right shoulder, now left shoulder and throughout both arms. My neck actually cracks when I move my head. The fatigue is debilitating. I am stopping both Zetia and Zocor. Will circle back to this site with the results F 61 2 years
1/29/2008
 1  Trying to lower the LDL Cholesterol It is incidious. I took it for a little over 1 year. The first few months were no side effects, then I noticed aches & pains in arm, hands,shoulders, leg muscles, all joints, loss of strength in my hands and arms. The pain got so bad that I could barely walk-only shuffle. The Dr. said "he had never heard of these side effects". I told him-"Now you have and I'm quitting this junk". This drug is terrible. I quit taking it and it took about two months to really feel better. I hadn't realized how much of a "brain dull" it was until I quit. It was like a light bulb turned back on in my brain, I could think, focus on things, remember and was no longer absent-minded. F 61 1 years
7/21/2008
 4  Elevated Cholesterol None Not many good comments so I thought I'd add mine. I've had good results so far. Cholesteral has gone from 240 to 169 with HDL of 49. Don't want to take statins. I exercise every day and watch my diet. F 60 10 years
3/26/2009
 3  High Cholesterol I had NO side effects I stopped taking Zetia today due to the "Enhanced Drug Study" results released by the manufacturer. It shows "no medical benefit" from Zetia even though Zetia does lower the total cholesterol numbers. In combination with Zocar the study shows an INCREASE in arterial plaque growth. See article in The New York Times Jan 14, 2008 business section. Per the article, "Dr. Steven Nissen, the chairman of cardiology at the Cleveland Clinic, said the results were “shocking.” Patients should not be prescribed Zetia unless all other cholesterol drugs have failed, he said." M 60 2 years
1/14/2008

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