ZETIA Reviews (EZETIMIBE)

Average Rating: 1.4 (601 Ratings)

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 HYPERLIPIDEMIA

 Type: Rx Drug

  

ZETIA  (EZETIMIBE):  Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. Ezetimibe may be used alone or with other drugs (such as "statins" or fibrates). Ezetimibe works by reducing the amount of cholesterol your body absorbs from your diet. Reducing cholesterol may help prevent strokes and heart attacks.   FDA Approval Date: 2002-10-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age oldest to youngest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZETIACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  colesterol after heart stint Constant ringing(crickets)in my ears.My skin itches and I sometimes break out in hives or rash. My feet burn and sometimes my feet and crotch burns. I have lost almost all the hair on my legs.I sometimes have hot flashes during sex and lately I have been experiencing a problem reaching climax during sex. No erection problem.I have alot of pain in my hips sometimes to the point I can't sit. After reading this site I stopped Zetia yesterday all together. I was blambing some of my symptoms on my age now I am unshure. M 55 4 years
4/3/2008
 1  lower cholesterol Severe muscle pain and weakness, elevated liver enzymes, tiredness, palpitations I had success with the cholesterol lowering properties of Zetia. However after 2+ years my liver enzymes were elevated and the doctor recommended ultrasound. Dx: fatty liver. Then wanted a CT scan which I refused. Discontinued Zetia. My severe muscle pain and weakness slowly began to lessen. My tiredness improved almost immediately. At 1, 2 & 3 months my liver enzymes were still elevated. At 5 months they are nearly normal. I test negative for hepatitis. At this point I can lay on my right side--not possible before because of severe pain and my right arm is now stronger. I still have a bit of lower back/side pain but it is much improved. I have moved to a holistic M.D. for care as I would like to work on the cholesterol elevation through more natural means. I am hoping for success with that as I do not think I will take Zetia again or any other statin. F 55 2 years
6/4/2008
 1  high cholesterol/triglycerides Abdominal pain at night-eliminated by taking in the AM. Pain and spasms in thigh muscles. Back pain. Heart palpitations. I couldn't take Pravachol, Zocor or Lipitor because of muscle pain but I think effects of Zetia is worse. F 55 4 weeks
11/21/2006
 1  Lower cholesterol Very bad and disgustingly smelly flatulence and extremely itchy thighs especially at night. Don’t know if it is actually lowering my cholesterol yet. M 55 60 days
10 MG
1/6/2018
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 1  cannot tolerate statins Severe pain in neck and shoulders. Stiff neck. Pain brought me to my knees, in tears, and I have a high tolerance for pain. Horrible drug, should not be on market or Drs should prescribe it for themselves 1st instead of using patients as guinea pigs. I would suggest to anyone to NEVER take this drug. Devil drug is right and I would not wish this pain on my worst enemy. Foolish practitioners to prescribe this drug. Made my recovery 100x worse and longer. F 55 3 days
30 1X day
1/8/2018
 1  High Cholseterol Severe chest and back pain, thought I was having a heart attack. Muscle soreness in rib, chest and back when not have the severe pain. I kept feeling more tired all the time. Finally one day I just couldn't get ready for work and called in sick, just too weak. My doctor kept telling me that Zetia is the milder of cholesterol lowering drugs and this drug doesn't have these kind of side effects. Because of all the pain I have had several tests for my heart. CT Scans, Untra-sound, nuclear stress test....the thought of putting the radioactive isotopes in my arteries and heart added even more stress. Mentally this wasn't a good situation either. I was feeling depressed and didn't care about anything or have any interest in anything. This was not like me at all. I had four months on the Lipitor and when the doctored switched me to the Zetia things got worse. The doctor did all these test instead of thinking of taking me off the Lipitor and Zetia. All these bad side effects just k Tell your doctor all the problems you are having and refer him to this site. The doctors need to know what is really going on, not just get their informaion from the pharmasutical companies and their reps. This stuff in dangerous. I hope there is not any permanent damage. I have have been getting better everyday. I am still having headaches, forgot to mention this above. Almost back to normal but I was in very bad shape from this crap. I am very athletic and this just through me and I didn't know what was happening physically as well as mentally. F 55 3 weeks
7/11/2007
 1  High Cholesterol Extreme fatigue, to the point that I don't even have any energy to exercise. I've tried taking this drug on 2 occasions, and both times experienced extreme fatigue. I tried it again just to be sure it wasn't something else causingthe tiredness. M 55 45 days
10/22/2007
 1  High Cholesterol Extreme tiredness. I've couldn't understand why I've been so tired these last two months. I know now that it's the Zetia. I started this medication two months ago and that is when my fatigue began. I'll call my doctor tomorrow and stop this medication after we've talked. I've never been so tired and unable to get out of bed before in my entire life. Thanks to everyone who posted symptoms. F 55 60 days
6/26/2007
 1  To lower cholesterol Severe pain in shoulder, arm and neck. Couldn't turn head. Hand trembled and shook when I lifted a glass or fork to eat. Began to have bladder muscle problems,incontinence etc.(I never thought it was the Zetia) I would advise you NOT to take this medicine! I have been off of it for 9 monthe now and feel much better. After 2-3 weeks of being off of it the aches and pains lessened and the urinary issues stopped completely.I never thought the urine leakage was related to Zetia until about 3 weeks after I stopped taking it and the problem stopped! If Zetia has this effect on arm, leg, neck and bladder muscles, I can only imagine what it does to your heart muscle! Muscles etc. are now better with no issues. If you are on it, get off. Dr. basically told me I was nuts and that no one has these side effects.I told him to take it & see how he feels. I stopped it myself-cold turkey with no other side effects except that I felt better!! F 55
10/10/2008
 1  High Cholesterol Felt almost like an anxiety attack..pounding heart, couldn't sleep, nervousness. F 55 2 days
7/18/2006
 1  Cholesterol over 300 Tried 3 different statins..I did try. Dr. put me on Zetia and 14 days into it now my lower back never stops hurting. Never had lower back pain a day in my life. I wake up and both my hands are completely numb. It hurts to move when I wake .. my muscles and joints hurt. I've thought we'll, this must be what it is like being 80-90! I am in very good shape. Gym 3X weekly and 30 minute walking my puppies daily. This is some bull sh*t!! It hurts to bend over and pick something up! Don't know what else I could take but I do know not taking this tonight or ever again. I was really hoping this would agree with me. F 55 1 days
10 1X day
9/5/2022
 3  Elevated Cholesterol Cold night sweats (pillow and sheets can become sopping wet), altered sleep patterns (which can explain why I am so tired during the day), unexplained weight gain, abdominal discomfort that can be mild (gas) to severe cramping followed by diarrhea, reflux, and after reading all this information unexplained mood swings, and a few episodes of leg cramps. If you think for one moment that all physicians are knowledgable about all medication side effects, think twice, most of us base that knowledge on pharmaceutical literature and journal articles. There is an old saying (which many new MDs seem to have forgotten)...... Take a moment and listen to your patient they often can tell you a lot more of what you do not know. I have been on Zetia for about 18 months and as of this morning discontinued it's use (good riddance). I will return to an exercise routine and a better diet and increase my dose of fish oils. niacin and garlic extracts (they do seem top have a positive effect on lowering my choleterol numbers) M 54 18 months
8/22/2007
 1  Cholesterol Extreme fatigue, muscle pain especially in the morning. Unable to take statins, due to muscle pain. Can't exercise right now if I had to. These side effects are touted as "rare", I don't think so, since I personally know of at least 8 friends this happened to. I am off of Zetia as of today. F 54 6 weeks
12/5/2007
 1  lower LDL cholesterol Palpitations, dizziness, anxiety, shortness of breath and felt like I was on "speed:. I couldn't sleep and felt generally uncomfortable. I have multiple allergies to statins and other cholesterol lowering options - plant sterols, red rice yeast, etc. I chalked my symptoms up to allergies but after reading all your comments, feel they were probably the same side effects some of you have experienced. F 54 3 weeks
11/21/2007
 1  High Cholesterol and Triglycerides I have been on Zetia for 6 weeks and for the past 4 weeks have had VERY painful cramps and stool like water. I don't know if it has lowered my numbers yet, but I'm DONE with this CRAP. this is no way to live! M 54 6 weeks
1/6/2007
 1  semi higher levels of cholesterol My doctor prescribed Zetia 10mg once a day along with Simvastatin 20 mg also once a day. I am 54 years old and enjoyed having sex once to twice a week. After being on Zetia for three months I noticed that I could not maintain an erection prior to sexual intercourse. M 54 3 months
1/7/2007
 1  High Cholesterol Severe muscle spasms in lower back and calves. I had an MI in 1995 at the age of 43. My Dad died at age 46 from a massive MI. I always ate a healthy diet so I assume my MI was due to genetics. I took statins and could not tolerate them due to muscle pain. Then started Zetia. Developed muscle spasms in back after 6 months. Stopped the drug 3 years ago and still having back pain. Have been to varied specialists who offer no reason for the spasms. I am convinced it is from the Zetia. F 54 3 years
7/19/2006
 1  cholestral made me achey and tired M 54 3 weeks
10 1X day
9/12/2010
 1  high cholesteral Muscle cramps in my legs, mostly at night but then during the day after about 3 weeks on med, also some cramps in torso muscles and hands; nervousness, hands shaking, feeling of general anxiety; weakness, not able to stand or walk with any energy. This is the only new med I am taking, so I think it's the cause of my malaise. Very grateful to people who have commented here. Calling Doctor Monday and telling him I'm off of this stuff! F 54 1 months
12/31/2006
 1  High cholesterol Several years ago, I took another cholesterol lowering med and developed gallbladder-like symptoms after about 6 months, so I stopped taking it. My cholesterol kept creeping up, so I agreed to give Zetia a try. After 6 months, the gallbladder-type pain was intolerable. An ultrasound was inconclusive, and I was sent home with pain meds I didn't want. The doctor wouldn't agree that Zetia was the culprit, but I discontinued it anyway, and the pain gradually subsided. I gave it one more chance, and started Zetia again, 3 weeks ago. From day two, I woke up very dizzy. In the afternoons, I was so tired, several times I fell asleep sitting up. But the problem that sent me to the internet to search was the depression-like waves of sadness and some irritability. Thanks for all your comments. After only three days without Zetia, I'm almost back to normal. Took Zetia about 6 months. Stopped for 3 months. Second time, only tolerated about 3 weeks. I'm fairly healthy, with some mild arthritis. I take no other meds, and I'm an RN. F 54 6 days
10/9/2007
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