RECLAST Reviews (ZOLEDRONIC ACID)Average Rating: 1.8 (234 Ratings)Filter ResultsCompare RECLAST with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
| RATING | REASON | SIDE EFFECTS FOR RECLAST | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | Osteoporosis | Debilitating and non-stop muscle pain (no other flu-like symptoms) in spine, hips, neck, etc. It started the day after my first ever infusion of Reclast (infusion is for one year; I will not be getting a second one). Pain took about TWO months to lessen at times but did not dissipate for FOUR months. | Endocrinologist who prescribed insisted pain could not be from Reclast; prescribed ibuprofen and told me to see my primary and then an orthopedist! A specialist no less, and yet he insists Reclast cannot cause chronic muscle pain. I went on line today and read medical studies. He might benefit from reading them. | F | 78 | 1 days 1X O | 4/5/2026 | 1 | Osteoporosis | It was the most horrible thing that I have ever gone through! It was worse than when I had Stomach Cancer, and that was pretty bad. I have never felt such horrible pain in my life, and high fever for a few days made me delirious. I could not even get out of bed! | I will NEVER take this again - it is like POISON! | F | 71 | 1 days 1X day | 2/13/2026 | 1 | Osteoporosis | One month larger developed severe hypertension 210/120. I am in great shape . Walk 2 miles daily. Been to Er 3 times in 2 weeks. BP always normal. There is a rare side effect like mine. Called an imflamatory response. Anyone have this? This is the only change in my history. | F | 76 | 1 months 1X O | 1/16/2026 | 1 | Bone loss | I'm no longer taking this medication. | F | 78 | 1X day | 11/5/2025 Patient History | 1 | Bone loss | I'm no longer taking this medication. I had one infusion. I am beginning to feel a little better after having all the side effects except vomiiting. I have a swollen ankle on my left side. I hope this is all I will have. I am not experiencing the severe fatigue and the flu symptoms. The itchiness continues. | I still think I will avoid another infusion. I will cross that bridge when I get to it. I was told by medical professional that there is no way to know if someone will have severe side effects or none. I am very skeptical of this treatment. The impact on my life has been severe. | F | 78 | 1X day | 11/5/2025 Patient History | 3 | chemotherapy induced osteoporosis | 12 hours after infusion started having discomfort across upper body. It got worse as the day went on, then fever, chills, just VERY uncomfortable, like flu, only worse. Thankfully my fever broke over night and I started feeling better, though still a little "off". | I read all the patient reviews on this medicine before taking it...actually chickened out in 2019 when my oncologist wanted me to take it.I drank enough water to float an aircraft carrier, took Tylenol and Claritin before procedure. I have an appointment with rheumatologist in 2 weeks. Will let her know that NEXT TIME I want the infusion nurse to bolus with saline, and run the medicine slower. | F | 68 | 1 days 1X O | 9/27/2025 | 1 | Osteporosis | Not informed about how much water to drink before infusion also pain relief. 12 hours after infusion dreadful bone ache , couldn't bend. Jaw,gum,ear pain. All of which I had pointed out before the infusion with the rheumatologist. Bone pain in spine and in my sacrum where I had fractures | I will not be taking this drug again. I felt better before it! | 69 | 0 days 1X AN | 9/15/2024 | 2 | Osteoporosis | The first 24 hrs were wracking pain! Horrible chills and the pain was so bad. Day two was much better. Day five now getying strength back. | F | 70 | 1 days 5mg 1X day | 8/9/2024 | 1 | Prevent breast cancer spreading | During the year on it had 2doses every 6months. Developped sharp hip/leg pains. Jaw pains. Skin rash. Low vit.D.Tooth decay. Dentist refused to work on my teeth fearing open wound could cause osteonecrosis of the jaw while on Zoledronic acid. | I decided to end zoledronic after 1 year although was suppose to have it 2 more years. Oncologists made a scene over my decision but I let them talk. I'm aware that cancer may now spread to my bones but I feel better being off this toxic med. Taking risk . | F | 54 | 1 years Intravenous 2X O | 7/11/2024 | 1 | Osteoporosis | I am still experiencing side effects 3 years after only Reclast infusion. Began experiencing excruciating bone pain in multiple bones/joints 36 hours after infusion that lasted 9 MONTHS. I continue experiencing extreme fatigue, brain fog, blurry vision, topical eczema type reactions, broken teeth. Had foot surgery 1 year after infusion and it’s taken 2 years for the bones affected to stop being extremely painful. I also began experiencing new autoimmune type problems immediately after infusion that are still unresolved. Almost impossible to get Dr’s to acknowledge or treat the damage! | This drug should only be given to people with advanced osteoporosis including multiple fractures. It should almost never be given as a first treatment for OP unless patient has had multiple fractures. This drug has a 10 year 1/2 life & there's no antidote & few treatments for those with severe adverse reactions. The drug mfg. has insulated themselves against legal action, so patients have no recourse or help with long term disabilities caused by this drug. I recommend exhausting all other options before agreeing to proceed with Reclast. Patients should advocate for a half dose for first infusion to hopefully decrease potential side effects. | F | 71 | 1 days 5 mg 1X day | 3/24/2024 | 5 | Bad osteoporosis | I'm no longer taking this medication. I am now on a drug holiday. A break from reclast for a few years. Per Dr., it will stay in system and offer protection for a year or so. This break to let your bones remodel normally for a while. I will continue to get dexas and go back on in a year or so. I've had no fractures and my mobility is better overall so i'm happy with Reclast. | F | 70 | 3 years 1X day | 3/12/2024 Patient History | 1 | Osteoporosis | I'm no longer taking this medication. Since taking this medication I have learned that 16% of all patients have a similar reaction as mine. I did file a complaint with the FDA however recieved no feedback. | Looking into natural methods of improving bone strength | F | 62 | 5 mg 1X day | 3/12/2024 Patient History | 1 | Results of a dexiscan | I'm no longer taking this medication. Severe teeth problems , still have pain ( sharp at times )lose of vitamins D improving a bit but still on treatment for deficiency | I will never take another treatment I continue to have problems. medication did excessive damage to my bones. | F | 80 | 6 months Infusion 1X O | 3/12/2024 Patient History | 1 | Endocrinologist recommended it. | 5 days of fever, nausea, vomiting and awful headache. Eye started to hurt, swell. Could not move eye. Admitted to hospital for four days for ocular cellulitis and elevated potassium. Constipation for ten days led to part of intestine developing infection. Back in hospital. | F | 75 | 0 days ? 1X O | 12/17/2023 | 1 | Breast cancer stage 3 ER+ | Had 1st intravenous zoledronic acid 1yr.ago to prevent Breast cancer stage3 from spreading in bones. No issues then but 6 months later after my 2nd.treatment I developped sharp hip/leg pains that are lingering to this day. Oncologist say it's not related to drug but I think it is. Recently saw my dentist who says my teeth have deteriorated quickly in last 6 months yet I practice good dental hygiene. A molar is cracked in half but dentist won't remove it cause I had zoledronic acid & it could cause serious infection/necrosis in the open wound of my jaw. My jaw hurts also. Tomorrow I'm phoning oncology nurse to cancel my 3rd.zoledronic acid due to be done next Friday....never again will I take this. It caused ongoing bone pains & deteriorated my teeth I was unaware it affected teeth. My oncologist will disagree with my decision but I'll let him talk. Avoid this toxic med. | F | 54 | 0 years Unknown 2X O | 12/10/2023 | 1 | osteoporosis | My wife was infused friday @ 2:30 pm. Friday night she had extreme muscle aches, chest pain, nausea , vomiting and urine incontinence. Saturday no better. Sunday emergency room. Very weak couldn't stand vomiting aches and taste of metal in her mouth. The hospital did a complete work also her BP was 220/ 98. All vitals were good and sent home. What a scare. I didn't mention she is 77 years old. Still in rough shape Monday. We hope this will pass. | This has to be the worst drug on the market. BE AWARE of what you're getting yourself into. The Doc's should WARN everyone of the side effects. Do a internet search and you will see the reviews for yourself. | F | 77 | 1 times 5mg 1X day | 11/13/2023 | 1 | Osteoporosis | Immediately after receiving the infusion my blood pressure dropped. I was extremely tired. RN was not concerned and let me leave. I was delirious. Thank goodness my husband was driving. Came home went to bed. Got slight fever and flu like symptoms. Was in bed for 3 days. Was sick to my stomach and extremely tired. 3rd day got a head cold and laryngitis was sick for one week with that. Doctor said not from infusion! I got my infusion on July 7, 2023. I have not had a normal day yet. My shoulders and neck hurt everyday. Like weights are on them. My hair is falling out. I have tingling in my left arm where I had the IV. I take a med for acid reflux - not helping now because it has gotten so bad from the Reclast. I have severe esophagus pain everyday. Can’t eat normal, food does not taste good and if I eat anything heavy I belch and suffer more. I am so tired. I am exhausted. This is awful. I can’t get answers. How long will I be like this? It’s only a link over a month. I don’t want to be like this forever. I am so unhappy and upset about the whole thing. | I wish my doctor would have gone over all of this before she said "this is the best thing for you." | F | 62 | 1 times 1X day | 8/19/2023 | 1 | Post menopausal osteoporosis | 12 hours post infusion woke up with severe shakes and ran fever from 104-102 with severe muscle aches/pain for one week. Couldnt keep food down for 4 days. Today is day 18 and I continue with daily fever ranging from 99 to 101 requiring Tylenol and frequent naps. I still ache but not as bad as first two weeks. The severe adverse reactions are only supposed to last for 7-14 days. Will there never be an end to this? | F | 1 times 5 mg 1X day | 8/18/2023 | 5 | Osteoporosis | None after first 3 days of infusion | Once per year for 3 years. Then on Tamoxifen for 10 years after breast cancer. Now reclast infusions again | F | 69 | 3 years 3X O | 8/1/2023 | 5 | Osteoporosis | I don't know how helpful this infusion will be but found it necessary to comment. I was very worried because my own sister had flu like symptom for two weeks (she's generally NOT the complainer: I am). After two days and I have had NO negative effects. Hope this gives someone else a little hope that not everyone gets a negative reaction, even though I was expecting one. Drink LOTS of water before and after! | F | 74 | 2 days Infusion 1X day | 7/19/2023 |
RECLAST (ZOLEDRONIC ACID): This medication is used to treat a certain type of bone disease (Paget's disease) that causes abnormal and weak bones. Zoledronic acid is also used to treat bone loss (osteoporosis) in men and in women after menopause. It may also be used to treat or prevent osteoporosis in people who are taking corticosteroid medications (such as prednisone) for long periods. It works by slowing the breakdown of bone and keeping bones strong. It also helps to reduce the risk of broken bones (fractures). This medication belongs to a class of drugs known as bisphosphonates. Another zoledronic acid product is used to treat bone problems that may occur with cancer. The 2 products should not be used together. (Sources: U.S. Centers for Medicare Services, FDA)
