LOTREL Reviews (AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE)

Average Rating: 2.5 (412 Ratings)

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 CALCIUM CHANNEL BLOCKERS ACE INHIBITORS

 Type: Rx Drug

  

LOTREL  (AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE):  This product is a combination of two drugs: a calcium channel blocker (amlodipine) and an ACE inhibitor (benazepril). It is used to treat high blood pressure. It works by relaxing blood vessels so that blood can flow more easily. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.   FDA Approval Date: 2006-04-11 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LOTRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Blood pressure I have a very dry cough, headach cough all night, votming, other time just tried. I think i will be asking my dr.to take me off of it. F 50 1 weeks
11/3/2007
 5  BP very bad hip pain, constipation, bad sore throat usually last for 3wks at a time blood pressure has been the lowest since i've been taking the medicine. Been taking it for 3 years F 39 3 days
10/31/2007
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 5  hypertension none; just significantly lower BP and I'm pretty happy about how quickly it worked for me. I never smoked, drink lightly, am slightly overweight (10 lb) and work out over an hour a day. My only problem recently as been elevated blood pressure at the Dr. office (home measurements are not as high and in normal range) and then it climbed up one day to 170/110 at the Dr. office. I noticed when taking meas. at home it was in the 130/90 range. The first day I took Lotrel, the readings were 110/70 and I was amazed. I have been on it 3 weeks with no side effects although this web site is very useful so I know what to watch for. F 53 3 days
10/26/2007
 1  HBP Brings BP down but cannot tolerate side effects. Experience shortness of breathe, rapid heartbeat, hair loss, and somewhat lightheaded. F 54 3 months
10/17/2007
 1  High Blood Pressure Headache, aches in muscles and joints, nausea, depression, inability to concentrate, fatigue, swelling ankles and feet My blood pressure has shot up over the last year, which I believe is stress related. At my last physical, my doctor decided I needed to start medication. I took Mycardis HCT (free samples) for three weeks. It did not make a difference in my blood pressure, but I had no side effects. Then my doctor prescribed Lotrel (10/20). My pharmacist gave me the generic version. Within the first day or two, I developed a massive headache. It was a strange headache, like a large clamp grasping the sides of my skull. Then my joints began to ache, especially in my back, hips, knees and ankles. My ankles developed painful swelling. I felt on the verge of tears, and could not concentrate at work. When I woke in the morning, I felt numb and exhausted, making it difficult to get out of bed. I felt nauseous all the time. I felt like I had been poisoned. I thought maybe the side effects would subside with time, so I hung on, but they got worse every day. I took the pills for two weeks. Final F 47 2 weeks
10/12/2007
 5  High Blood Pressure none Wow! I love this website! It's amazing the range of effects people have. I have had absolutely no problems with Lotrel. I got pregnancy induced hypertension that did not go away with birth, but actually spiked. There were several stroke scares and many hbp meds tried before Lotrel finally worked. I've now been on it for 5 years. I read the many side effects some people have had and am shocked because I've had none with this drug. I've had horrible side effects with some of the others we tried. The coughing seems to come and go and can get annoying. It seems worse when I'm stressed. But other than that, nothing. F 43 5 years
10/1/2007
 1  hbp I have taken Atenol for several years. Recently my Doctor changed me to Lotrel 10-40 because the medication seemed to stop working. After a couple of months on Lotrel I am having spells where I can not grasp words that are being spoken to me or speak for approximatly 60 seconds. The best I can describe this is when hit on the chin the feeling right before you black out. My motor skills do not seem to be deminished during this time, however I get a loud noise in my ears, again for a lack of comparison much like the sound a huey helicopter makes. I have also experienced soreness in my hips. I have worked out with weights (heavy at times) for almost 20 years but seem to be so stiff that I have to adjust my work out to accomodate the stiffness. At nights I have an extremely hard time falling asleep and it is impossible to wake up in the mornings. Tommorrow I will insist on a new medication for my Hypertension. M 41 3 months
9/25/2007
 4  to control high blood pressure None Have had no side effects from this drug, and seems to be effective. Since a generic is now available, the cost of the drug is no longer a concern. F 47 2 years
9/17/2007
 1  high blood pressure turso rash scrach till i bleed.had to use anti itch cortorzone to sleep at night. took about 2 years to discover it was lotrol. M 70 2 years
9/17/2007
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 1  hypertension coughing... coughing and coughing. I blew some blood vessels in both eyes, coughing so hard. Losing lseep from the coughing.... even while on ambien. While it did lower my BP and had me feeling better, the coughing fits have sent me over the edge! Have lost 20 lbs since starting exercising and feeling better in the beginning ... but the coughing is NOT worth it. Switched to norvasc today. F 37 2 months
9/13/2007
 2  high bp fatique, hacking cough, imsomnia, swelling, leg and foot pain, mostly at night and upon rising in the morning I was told this drug was best for african americans. I kept telling every doctor that I saw, I was extremely fatiqued, coughing, blurred vision, and muscle pain. Walking was difficult and I went nights without sleep. I took myself off Lotrel 10/20, told the doctor to give me a generic. It's been 1 month now, my legs still hurt, hurts to walk and I am still tired, not as much, so I'm hopeful I will start to feel better soon. I still have imsomnia, that is how I found this site, looking for answers. Don't take this drug! LK F 55 2 years
9/9/2007
 1  high blood pressure (140/90) Sudden and severe nausea on the morning of day 10 - thought I was going to pass out. Flu-like symptoms throughout the remainder of the day: pounding headache, fever (100.8 F), weakness, body ache. Days 1 - 9: tired, cranky _despite_ the Adderall XR! Lotrel Dosage: 40mg Also taking Lexapro (20mg) and Adderall XR (20mg) M 36 10 days
8/30/2007
 3  High Blood Pressure Swelling in ankles; loss of sex drive and performance; increased depression; weight gain Blood pressure was lowered. Switched to this medication after Toprol XL proved ineffective in lower blood pressure. F 39 1 years
8/28/2007
 2  HBP Fatigue, dizziness, depression, shortness-of-breath, sleep disruption, closure/swelling of the larynx Did lower my BP but the side effects are too much to take. M 53 75 days
8/22/2007
 4  HBP Ankle swelling, coughing at first, anxiety (might be work related), hypotension with strenuous exercise. Taking 10/40. Stuff worked OK -- got BP down to 120/80 from 140/100. I feel OK generally, but excessive ankle swelling has my wife concerned. Also experienced same in hands once (during 9 mile hike). I also took a pill (first one) right before a 90 minute game of 3-on-3 full court B-Ball. I won't do that again. I could barely lift my arms over my head and felt really weird. BP was about 90/50 when I got home. I'm going to see if Doc can adjust something to minimize or eliminate swelling. M 43 2 months
8/20/2007
 3  hypertension Extreme hypo-tension immediately after mild exercise, such as biking/jogging. So bad that after a short ride this past weekend I collapsed in my driveway, too dizzy to stand and on the verge of blackout. After about 15 mins I was able to put my bike in the garage, but had to lay down again before attempting to get inside. Once inside, I took my blood pressure...108/61 hr-96. Considering my systolic averages 140-150 with this medicine, no wonder I almost blacked out. Have only experienced this since my doctor upped my dosage of lotrel. I have an appt tonight and will request we try something else. slight cough, nothing bothersome. Constipation M 31 6 weeks
8/7/2007
 2  high blood pressure Imbalance, swelling of lower limbs, dizziness, loss of appetite, fatigue, not energetic and able to do many daily activities, shortness of breath. While visiting family for a couple weeks I felt so bad that I went to the hospital and they kept me for four days running every test conceivable,with no conclusions except that I had not had a stroke, heart attack or any other life threating condition. after reading comments from others on this page I have finally decided to get my doctor to switch me to another medicaiton. Lotrel did lower my blood pressure but the side effects are too severe. M 73 3 days
7/12/2007
 1  high blood pressure hacking cough, had to be transported to hospital, because my tongue was swelling and i could not breathe.I relayed this information to the doctor and she said I had anallergic reaction to something I ate. The medical emergency responders were called as my husband and I set in the car,waitng.In the meantime a man walked up to see if he could offer assistanc and prayed with us until help arrived.The ER department said I was stridor or was striding.It makes me so angry that neither the hopital or my doctor questiond that I was on Lotrel and am African American. This happened almost 2 years ago and my doctor prescribed medication for my hacking cough,which does not work. 2 months ago,I was looking through a medical book at work and found that taking lotrel can cause death in some people because of the swelling of the throat. At the hospital I was given doses of ephenephrine. On medical phamplets, this is not listed and something should be done about thisBy the way,I was told at the hospita F 54 2 years
7/12/2007
 3  High Blood Pressure Tired, no energy and not myself. Also feel somewhat depressed and not myself. I have gastric problems but since taking Lotrel it seems to have intensified. I also cough a bit for no reason as I rarely cough. It is quite irritating the overall feeling. My dr. tried me on it earlier this year because my BP was in the 140's/90's range and it brought down my BP to the 120's/80's range but the side effects bothered me so I stopped after a couple of weeks. At my physical, the dr. said my BP was elevated and he once again suggested Lotrel and said to give it more time which I did. Today will be my last day with this medication because I feel absolutely terrible. The anxiety, irritability, nausea, cough, depression and overall tired, malise feeling will not make up for taking it. My blood pressure has come down into the 120's/80's range from 140's/90's but is definitely not worth having all these side effects. I plan on going back to my old BP medication, try to lose some weight and exercise more. I don't recommend this drug it makes you feel "not yourself". F 49 3 months
7/10/2007
 1  High Blood Pressure I thought I was having heart problems with a pounding heart and tightness in the chest but my dr's tests didn't show any problems. Now they are going to check for a hiatal hernia. Aside from the abovementioned problems, I am also experiencing anxiety/nervousness, muscle aches, a slow pulse, and sometimes nausea. I asked the Dr. about side effects of Lotrel and he wants to wait until after the EGD scope. I just started thinking about possible side effects of my meds and found this site. Seems a lot of other folks are experiencing the same or similar symptoms I am. I get the scope tomorrow so we will know shortly if it is a hiatal hernia. My money is on the side effects though because after thinking back, these symptoms started around the time I started taking the med but they weren't bad so I really didn't pay much attention to them. But the symptoms got worse as he upped my dosage. After this last bad bout, he wanted to put me on 10/40 but i found some 5/20 that I had saved and started taking it again. I didn't want to quit it cold turkey but the decreased dosage has caused my symptoms to decrease also. You do the math. I see the dr. in about a week and I am going to ask him to switch my meds. M 43 2 years
7/10/2007
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