LOTREL Reviews (AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE)

Average Rating: 2.5 (412 Ratings)

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 CALCIUM CHANNEL BLOCKERS ACE INHIBITORS

 Type: Rx Drug

  

LOTREL  (AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE):  This product is a combination of two drugs: a calcium channel blocker (amlodipine) and an ACE inhibitor (benazepril). It is used to treat high blood pressure. It works by relaxing blood vessels so that blood can flow more easily. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.   FDA Approval Date: 2006-04-11 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LOTRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  high bp I have been hacking my brains out. So much dry coughing that i feel like i'm going to cough up a lung! If I don't sleep soon, I'm going to melt down!!!!!! F 39 1 months
3/1/2007
 1  high bp very swollen ankles, constant dry cough which turned into two bouts of bronchitis, the second quite severe, weird dreams, facial flushing when leaning over, lightheadedness when coughing too hard; it did lower my bp to 120/80 or a bit lower. Couldn't live with it, though. Finally gave up. Mom takes lotrel with no side effects at all that she can think of. F 50 90 days
2/28/2007
 2  hypertension Unfortunately Lotrel gave me serious gastrointestinal upset so much so that I thought I was developing irritable bowel syndrome. Also, I would get swollen lower legs and ankles by the end of the day each day I took Lotrel. I had to stop after nine days. It did lower my blood pressure but the side effects were dreadful. The GI problem stopped within 48 hours after stopping the Lotrel. I gave my leftover pills to a friend who has used Lotrel for months with no problem at all; he was pleased. F 65 9 days
2/26/2007
 2  high blod pressure Worked fine for a time then I found that my daily walk of 4 miles would lower my pressure to 75/55, which would make me very woozy. I will be 74 in less than a month. The doctor took me off the lotrel and prescribed Benazepril which seems to work so far. M 73 4 days
2/14/2007
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 3  Hypertension Took it for about 5 yrs, no immediate problems recently had issues with palpitations and constant coughing. Dr.told me this is a side affect of the drug especially in African Americans. Change medications. Still have some coughing but slowly improving. Have sipped on vinegar (1tsp and water 6 oz) to help F 56 5 years
2/2/2007
 1  Hypertension Severe dry, hacking cough, choking, gagging, vomiting, swollen throat, hip and leg pain. Cough and choking increased at night causing inability to sleep/fatigue. It helped to lower my blood pressure, but the coughing and choking were so severe that I could not breathe. My throat was so swollen shut that it was difficult to even take 1 pill at a time (I used to be able to take a handful of pills at a time with no problem). I felt like I had bronchitis all the time and was tired from lack of sleep. The hip and leg pain began at the end of my 3 month use of this drug. I had been fine the day before, but then I had diffulty walking after sitting in the car. I didn't know it was related to Lotrel until I read some of the comments on the site. F 48 3 months
2/2/2007
 4  High BP Lower sex drive. Usual ED meds are not effective while useing Lotrel. Going to Boston Medical today for evaluation. Male 50 yrs, sex life is important. Anybody have optional suggestions? M 50 6 months
1/29/2007
 5  HBP Absolutely none. Have been taking it for over 3 years. My blood pressure problem was the low end. It was 100-110. Lotrel lowered it to 72-80. What many blood pressure patients don't understand and I don't care what a doctor tells you, caffiene raises your blood pressure as well as a poor diet (meaning don't skip meals, eat at normal intervals). Also if you have something like chronic back pain, like myself also adds to your blood pressure. You mix these with a stressful job and you are sure to get high blood pressure. Unfortunately, it's the good people who try to do an excellent job and care about their performance who this affects. If you don't care you don't have anything to worry about and you won't get high blood pressure. Continue taking, don't drink anything with caffiene, exercise, eat at normal intervals, do stretching exercises if you have back pain, talk with your boss and let him know your blood pressure problems. If he doesn't care go to Human Resources or Safety, they do. If all else fails tell your boss to kiss your ass, because my 2 year old daughter would rather me working at McDonalds than not having me around. M 45 3 years
1/27/2007
 1  
1/21/2007
 3  HBP Tired,out of breath,heaviness in legs. F 43 4 days
1/18/2007
 2  high blood pressure I am experiencing itching, swollen ankles and severe leg pain. I want to get off this drug but my doctor hasn't been able to find another hbp drug that will control my hypertension. Any suggestions for an alternate hypertensive drug that controls hbp would be appreciated. F 54 6 days
1/13/2007
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 5  hypertension Worked great for about 2 years then severe edema clicked in. Could not wear any shoes without laces. Dr. switched me to Diovan hct (80mg/12mg). BP went up and stayed that way for months. Called Dr. and he doubled the Rx to 160/25. Came down but still high (anywhere from 200-150/103-86). Will see Dr. to discuss alternatives. Seemed to work very well for a few years, then ????? M 65 3 years
1/7/2007
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 3  High blood pressure readings I have been coughing to the point of choking and gagging. Up at least twice a night with coughing spasms and dry throat. Drinking water does not help to eliminate the dryness. Seems like a high price to pay to lower the readings. Drove myself to the emergency room last week because of "strange" feeling while Christmas shopping. Sensed something was terribly wrong. Only consolation was, I was never short of breath and no chest pain or numbness in arm or jaw--just terrified and knew something was NOT right. Eight hours later with brain and lung scans, plus chest x-ray and EKG results in, nothing found to be abnormal. First prescription medication I have ever taken in my life--very disappointed with side effects, but suppose I should be glad the BP is now 120/70 instead of 170/102. Everyone fears the "silent killer" so we stay on the medication trusting our doctors who supposedly know best, but they are human and can't possibly know everything about every drug. Know your body and how it works, recognize when things don't seem right and speak up. F 58 3 months
1/2/2007
 1  High BP Lower muscle and joint pain, depression, anxiety, total feeling of doom, fear, wanted to die. I have been taking Lotrel 5/20 and had the pain and mild depression. I didn’t associate it with the pill. My bp was controlled, after a year it started a steady increase. Dr. increased dosage to 5/40 after looking back that’s when I started to feel “not me”. BP still increased he upped my dosage to 10/40. All the above symptoms hit within three days plus metal taste in mouth. Went back to 5/40. After the side effects of the 10/40 this seemed to work, BP went up again. So he tried the 5/40 morning, with Avalide 300/12.5 and the 5/40 at night. I am normally a happy positive energetic 60 year old male, I would sit and cry like a baby, wanted to die, terrible feeling of doom and fear, extreme arm, back and leg pain. Couldn’t sleep even with Avalide CR. Called today and told him I can’t take this any more. Also can’t take Diovan or Norvasc. This will be int Should be taken off market. M 60 2 years
1/2/2007
 5  HBP The only side effect I've experienced is minor foot swelling. However it is a lot less than when I was on Norvasc only. With Norvasc it was everything from the ankle down. With Lotrel just my toes mostly. Have the "hot foot" in general to the point that I can't wear my boots anymore. Toes so sensitive it's uncomfortable to trim my toe nails. No sexual side effects. Actually the vasodialator part works really well. :) It works and I'm staying with it. I've had the swollen foot side effects with every BP med I've taken. Lotrel is the least and my BP is under control. I like it. M 42 1.5 years
12/29/2006
 2  high blood pressure Constant pain in back, neck and shoulders. Coughing and wheezing in the evening. Lungs feel tight. Feelings of sadness and discouragement. Cannot tolerate the cold. Feet always cold. Any chance I get I am lying on a heat pad for my back, neck or shoulders. My doctor gave me two different antibiotics. Also gave me an inhaler. He indicated I had asthma symptoms. It felt like I was getting pnemonia again except for the sweat attacks you get at night. I took my last pill last night and it shall be the last pill. Doctor will try s/th else. M 51 3 months
12/29/2006
 1  HBP I've had swelling in the feet that makes shoes tight & uncomfortable and causes considerable ankle pain when walking or driving. I only took the drug for 4 days. At first, I noticed some swelling but no great pain. Now, I'm very frustrated because of the discomfort and pain. I've been off the drug for 3 days, and there's been no reduction in the swelling yet. In fact, the worst pain has occurred in the past 2 days. F 48 4 days
12/17/2006
 5  HBP NONE TE GREATEST BP MED EVER M 57 2 months
12/8/2006
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 4  High Blood Pressure Initially a slight headache and upset stomach; then for about a month everything was fine. Unfortunately, I've developed the cough that is driving me crazy - it gets worse just before bed and as I am trying to fall asleep. It has lowered my blood pressure from a high of 160/100 to about 130/80. F 28 60 days
11/30/2006
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 1  High Blood Pressure Terrible cough and breathing problem. I also gained a lot of weight F 70 6 months
11/25/2006
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