LOTREL Reviews (AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE)

Average Rating: 2.5 (412 Ratings)

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 CALCIUM CHANNEL BLOCKERS ACE INHIBITORS

 Type: Rx Drug

  

LOTREL  (AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE):  This product is a combination of two drugs: a calcium channel blocker (amlodipine) and an ACE inhibitor (benazepril). It is used to treat high blood pressure. It works by relaxing blood vessels so that blood can flow more easily. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.   FDA Approval Date: 2006-04-11 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21


RATING  REASONSIDE EFFECTS FOR LOTRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Hypertension Increasing fatigue, profuse sweating, and concentration problems. Started on a 10/20 dosage 3 years ago as a replacement for Zestril which my insurance provider would no longer cover (but it worked very well). Lotrel worked well at first, then after 2 years my body got used to it and increased to 10/40 dosage. Noticed obvious increase in sweating, nocturnal urination, long and short term memory problems, dizziness. Did not notice any ED problems. Fainted on standing a few months ago, checked BP (while standing) but it was not abnormally low. Started checking BP twice a day while still taking 10/40 and it seemed normal (averaging around 120/80). Left a stressful job a few months ago and thought I'd check BP without taking Lotrel for a few weeks to get a new base reading. No difference with or without taking Lotrel now. Time to find something new (if needed, hopefully not). It's worth trying to see if it works for you but good idea to monitor its effects at least occasionally and note the common problems people are reporting with it. M 52 3 years
10/40 1X day
12/14/2010
 3  High Blood Pressure Day 1-Nothing; Day 2-Dizziness and Nausea for an hour after taking; Day 3-Severe dizziness and nausea, extreme anxiety and depression, loss of appetite, body aches Within a few hours of the first dose, Lotrel did lower my blood pressure to 135/80. Before getting pregnant, my BP was always 120/80. After giving birth, my blood pressure ranged anywhere from 140-180/80-110. So overall, it worked at lowering my BP but the side effects are too much for me. F 27 3 days
10/20 1X day
12/2/2010
 3  Hypertension Lets see Im probably the youngest on this site unfortunately and i am very active .....or at least i was. since Ive been on the medicine I have been tired and weak, when before i was a track runner, basketball, bowling, you name it i love to play it and now i lost interests in not only sports but it seems like life. I have no interests but in my bed now. At times i also gets bloating and slight pains in my abdomin when im no where near my monthly. The only reason im giving this medicine a chance is because my mom who has it, hypertension(although she didnt get it til she was 45), was using it and the doctor thought if it works for her maybe it will for me. but she swelled a lot and is now off it and after doing research i found out that it can cause asthenia wich is weakness of muscles and cause tiredness!!! eventhough it brought my hypertension stage 2 (185/117) to 120/90 I am going to ask my doctor for somethn else and this time i wont tell him what my mom is on cause even if it help It works but it hasnt been properly studied and for a younger age group i think its just all wrong since it can cause asthenia. F 24 9 months
5/10 1X day
11/29/2010
 5  Hypertension No noticable side effects. Dr. added 25 mg Atenolol, because I can't do water pill. Been rather happy with results. F 56 10 years
10/40 1X day
11/19/2010
 1  HBP Took 5/20 for about a year with little in the way of side effects but it didn't help with lowering my BP either. Went to the higher dosage and within 30 days I was a wreck - severe swelling in both lower legs, large area of rash, pain in back, knees, lower legs and feet so bad I could barely stand up much less walk. Then there was the numbness in the feet - I had almost no feeling below my ankles. I've been off Lotrel for over a year now - the pain has gone away and I have regained movement in my lower legs and feet. The rash is finally healing but I still have a little numbness in my feet and toes. I would not recommend this poison to anybody and I haven't even commented on some of the other side effects like ED, urination problems and continuous fatigue. I've got to believe there will be an ad on TV before long by some lawyer for anyone who has taken this drug. When it comes, I'm going to be one of the first to call. M 64 2 years
1X day
10/19/2010
Email
 5  HBP No side effects that I can find now. First 2 months there was a slight increase in coughing but that went away. Lowered my BP from 145 over 92 to ~120/78 M 68 2 years
5/10 1X day
9/13/2010
 5  hbp none Had an aortic valve replaced[st judes] with an aortic root disection due to a 6.2 aneurism. The disected aneurism was replaced with a dacron sleeve.My BP needs to be low because of the aneurism. BP is 108/60...PR 58..I run a landscape business with no shortage of energy. Best BP medicine on the market. M 62 8 years
10/40 1X day
8/25/2010
 3  HBP swollen ankles and lower legs took 5/10 for one year all good doctor changed me to 5/20 still ok. doctor changed me to 10/20 began to have side affects F 53 2 months
10/20 1X day
8/22/2010
 2  Initially LOTREL now SANDOZ Reduced high blood preasure,But left leg below knee swollen. Heart rate abnormally low at 50ties most of the time.Today Dr. asked to stop this medicine & prescribed another, Not happy with it. M 47 4 years
20 mg 1X day
8/6/2010
 3  HBP Greatly helped my blood pressure, but has knocked my you know what in the dirt. Also found the need to take a 2-3 hour nap after work each day. Started having problems with kidney function ranging between could not urinate to urination frequently. Today is the last day that I will have taken this medicine - I am calling my doctor on Tuesday. M 46 40 days
5-40 1X day
7/4/2010
 4  bp M 54
10 40 1X day
6/22/2010
 2  hypertension swelling of lower legs, ankles, and feet. Tenderness, pain, and redness in feet. I was switched to Lotrel from HCTZ and lisinopril. There were no Lotrel side effects for 2 weeks and then began noticing swelling in lower extremities. I've been off the drug for 5 days and the swelling and pain lingers. Was told by MD to return to HCTZ and Lisinopril which was very effective in lowering BP and had no side effects. M 63 22 days
10/20 1X day
6/10/2010
 2  high blood pressure Swollen legs and ankles, leg fatigue M 67
10/40 MG 1X day
5/31/2010
 5  HBP None, Maybe because I am only 35, but geez some people are just weak or over-responsive to drugs I guess. Worked in lower BP from 135/85 to about 120/80. Not a huge change, but helped. M 35 4 years
10/20 1X day
5/13/2010
 5  HBP None. I read many negative comments about this drug. All I can say is that for me it dramatically lowered my BP. Before taking it BP was 150/95 after 134/74. Don't think that you will have every side effect that people here have had. If your DR orders it, give it a try and keep an open mind. The HBP is much worse. M 62 45 days
5/40 1X day
5/13/2010
 4  HBP Blood pressure is great. Switched to lotrel because of serious swelling issues on another calcium channel blocker. Doctor told me one in five would develop a cough with lotrel, and to call his office immediately if I did and he would switch me. I was told to go have a blood test for kidney function a couple of weeks after starting as well, so I will be doing that Monday. I had some dizziness the first week, but it is gone now. Overall, I am much happier with this medication than the other medications my doctor has tried for me. The others had very little effect on my BP. With Lotrel, I am down to a normal range. I developed HBP during pregnancy that has never gone away. F 37 14 days
1X day
4/4/2010
 5  high bp none M 53
10/20 1X day
3/8/2010
 2  HBP THE FDA NEEDS TO CHEMICALLY ANALYZE GENERIC AND BRAND LOTREL(SANDOZ). BRAND LOTREL FOR THREE YEARS WITH HARDLY ANY SIDE EFFECTS. NOW ON GENERIC LOTREL BY SANDOZ, A DIVISION OF THE COMANY WHO MADE THE BRAND LOTREL. BLURRED VISION, BURNING SENSATION, GROGGY, CLEARER THINKING, WATER NOT RETAINED. CHINESE COLD WAR CHEMICALS USED IN THE MAKING OF THE PILLS, EVEN THOUGH THE DRUG IS MADE OUTSIDE OF CHINA? A BAD CHEMICAL? THE OLD LOTREL FROM A FEW YEARS AGO WAS SAFER OR SO IT APPEARS TO ME. BRAND LOTREL FOR THREE YEARS WITH HARDLY ANY SIDE EFFECTS. NOW ON GENERIC LOTREL BY SANDOZ, A DIVISION OF THE COMANY WHO MADE THE BRAND LOTREL. BLURRED VISION, BURNING SENSATION, GROGGY, CLEARER THINKING, WATER NOT RETAINED. CHINESE COLD WAR CHEMICALS USED IN THE MAKING OF THE PILLS, EVEN THOUGH THE DRUG IS MADE OUTSIDE OF CHINA? A BAD CHEMICAL? THE OLD LOTREL FROM A FEW YEARS AGO WAS SAFER OR SO IT APPEARS TO ME. M 58 7 days
5-10 1X day
3/4/2010
 2  high blood pressure Works great at lowering my blood pressure--side effects not too bothersome at first. Feet and leg pain, which I attributed to my job as a waitress, constant coughing, shortness of breath, but it gets worse the longer you take it. Last 6 months, developed SEVERE lower back/hip pain on left side, which sometimes spreads across entire lower back...pain so bad, it sometimes brings me to tears while working. Then about a month ago, mental depression set in. I'm normally a very happy, energic, out-going person. I became withdrawn, unusually sensitive, irritable, lethargic--everything I am not! I missed a couple of doses of this poison 2 weeks ago, and guess what? I FELT GREAT!!! NO PAIN AT ALL!!! I WAS HAPPY AGAIN!!! I wasn't constantly short of breath, wasn't coughing, had energy...just felt like my old self again! Went to Dr. today, told him how I'd been feeling, told him how I felt when off the Lotrel. He told me, no, he had NEVER heard of Lotrel causing those side-effects-tried to get me to take anti-depressants-I said no! I insisted it had to be the Lotrel. He's sending me for back x-rays (guess he doesn't believe me) and switched me to tenormin 25 at night and norvasc 10 in the morning. Tenormin is a beta blocker (YUK!) and norvasc is one of the poisons in Lotrel! I don't think I'll do any better on these new poisons, but I have no choice but to try them. I go back in 2 weeks...time will tell. If he can't switch me to something that doesn't cause such debilitating side effects, I'll just have to find a new Dr. F 56 3 years
10/20 1X day
2/23/2010
 1  High Blood Pressure Weight loss at first (15 lbs), lack of appetite, slight coughing, thought was my asthma/GERD, then severe depression, lack of energy/motivation, anxiety, tired all the time, can't sleep at night from coughing, extreme coughing causing gagging and throwing up, sleepy all the time, can't concentrate, nasal congestion, isolated myself, couldn't do much. Up many times during the night from the coughing. Sometimes insomnia. Started to have leg swelling. I was happy at first that this drug suppressed my appetite and helped me to lose weight but the benefit of this stopped after a few months with no more additional weight loss and ensuing bad side effects. It DID help with blood pressure, but not worth the side effects. Didn't know what was wrong with me, had a bad cold, then it seemed to get worse plus I have asthma and GERD so thought it was that, am on Triminterene (sp?) plus the 5-20 generic lotrel, loved it at first since I lost weight, helped my BP a lot! Never had it so low, but after a couple of months, my life deteriorated and now I was wondering what is wrong with me and how unhappy I am. Not really knowing why. After reading what other people wrote I know that this is the same problem. Stopping it as of today! I want my life back! I was also on Linosipril and it also caused me to cough a lot. I've been out of it since October 2009 to today February 17, 2010...doctors can't figure out what is wrong and treat my symptoms not mentioning possible side effects of Lotrel. F 43 7 months
5-20 1X day
2/17/2010

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