LOTREL Reviews (AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE)

Average Rating: 2.5 (412 Ratings)

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 CALCIUM CHANNEL BLOCKERS ACE INHIBITORS

 Type: Rx Drug

  

LOTREL  (AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE):  This product is a combination of two drugs: a calcium channel blocker (amlodipine) and an ACE inhibitor (benazepril). It is used to treat high blood pressure. It works by relaxing blood vessels so that blood can flow more easily. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.   FDA Approval Date: 2006-04-11 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LOTRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  high blood pressure coughing and leg cramps F 58 4 weeks
5-20 mg 1X day
2/10/2010
 5  high blood pressure I do not remember any side affects worth mentioning I started taking Lotrel 10/20 (4) years ago after a physical at work revealed HBP and I was told by the nurse to get medicated .. everything was fine until I retired & when I was going to have to pay for it myself, I decided to just quit taking it .. anyway I had been monitoring consistently, both at home & at work .. I was in the 120/60 range on the Lotrel .. when I quit it the BP started going up, sometimes 180/90 or even slightly higher, which is no big deal to me considering some of the propaganda you read nowadays saying high blood pressure may not be that bad after all .. anyway, I started getting these, what I call Ice pick headaches maybe a few time a week & lasting only a second or two, so decided to go back on Lotrel to see if the headaches subside .. just picked up a prescription today & will update progress in a month or two .. or M 68 2 years
1/29/2010
 3  high blood pressure extreme burning of both feet on minimal exercise I am used to being able to take long walks but now I can only stand on my feet about 20 -30 minutes before I experience debilitating weakness and burning in both feet there is only minimal increased swelling of lower extremities I HAVE BEEN ON LOTREL 10/40 ABOUT 6 MOS. F 67 6 days
1/17/2010
 1  high blood pressure Took Generic Lotrel for 2 months. It did lower my blood pressure, but caused horrible hip/leg/knee pain. I stopped taking it 1 month ago, but the leg pain still persists. I am unable to sit for longer than 10 minutes without pain. F 42 2 months
12/26/2009
 1  Blood Pressure Loss of voice, extreme asthma type systoms, dizziness, can not sleep, hypertension and exteme foot pain. My husband has taken Lotel for 2 years. He has experienced extreme foot pain, over the past two years has been treated for extreme "adult" asthma, with every inhaler known to man. In the past 6 months, we have been to numerous specialists, cario, lung, alergy, ENT, have had CT scans, ekg, echocardio gram, blood tests, hospitalized, etc. Last week we finally saw a great doctor who specializes in Critical Care & internal medicine , who told us that my husband either had the worst lungs on the face of the earth, or the worst case of asthma he had ever seen, OR his real gut feeling was - it is the LOTREL. He took him off the LOTREL, advised that it would take 2 weeks to feel better and be able to breathe. It has been 4 days and his voice shoulds so much better, just waiting and praying that all of the other side affects go away too. This is terrible medicine! My husband has really suffered while on this medication, and it did not really help in lowering his BP. M 66 2 years
12/7/2009
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 1  High blood pressure Extreme foot pain while walking, swelling legs, depression, dry swollen nasal passages. I took this drug for about a year-6 months ago dosage was incresed and that was I started to notice the problems. I went to the orthopaedic doctor and they found nothing wrong with my feet. I knew I had to find a reason for my discomfort and started researching medication side effects and found this web site. I call my doctor right away and requested a different blood pressure RX. Within 2 days edema was gone. It took about 8 days for my feet to start to feel better. I want to thank others who posted. You helped me to figure out what was causing my problems--not the doctors or the drug web disclaimers. I can not even begin to tell you how much better I feel overall. F 50 1 years
12/4/2009
 1  High blood pressure Dry nasal passage, joint pain and pain in my feet so bad I could barely walk at times. PCP and orthopaedic doctor could not see anything in x-rays. (previously tibula repair with left rode) thought maybe a stress fracture. I am thankful I found this web site and saw other were experincing foot pain also. Called dr for a new RX. Hopeful pain/discomfort will get better. Pain had already affected my life style. Foot pain last 2 months or also. Joint pain longer-but unsure of a specific time. F 49 365 days
11/23/2009
 1  High Blood Pressure I have been on Lotrel for appooximately two years. During the first few weeks, I didn't notice much change. Then I noticed the fatigue and body aches over the next 9 months but did not connect it to the Lotril. On November/08 I was at deer camp and had severe back and under the rib pain. Had my wife drive me to the emergency room. They run cat scans, MRI, blood tests and no one could figure out what was causing the problem. After November the pain moved from my back to my hips and legs. My feet and hands begin to swell which made sleeping very uncomfortable. Doctor could not figure it out. Four weeks ago my script was doubled from 5-20 to 10-40. HOLY CRAP..I thought I was dying. I even considered ending my life. I could barely get out of bed, slept most of the time, stomach was bloated and had all the symptoms as earlier mentioned. I am quiting the drug today and will let you know the results. Why doesn't the FDA do something about this? This drug should be investigated by FDA. This drug could kill!! M 55 2 years
11/5/2009
 5  HTN only first week, nausea, dizzy and Lightheaded when standing up to quickly. After week mild general weakness, week 2, no general complaints now. All my symptoms are normal, and were expected. I went from a normal non active bp of 160ish/100ish, up to 180/120ish active. You have to remember going from a high BP like this to 120/70ish is a big change for your body to adapt to. There will be side effects for a short time, and they should eventually level out, if you don't feel these side effects, the drug is probably not working for you. How many years did you have HTN as the norm, vs how long have you experienced normal BP? 3-4 days vs 20-50 yrs plus?? Plus, ALL drugs have side effects. M 31 6 months
11/2/2009
 1  Hypertension After one month taking Lotrel 10/20, I experienced loss of concentration, fatigue and slight edema on my lower extremities but my blood pressure went down from 196/96 to 130/74. No headaches anymore. Bld. Pressure went back to normal. After the second month, I felt the pain in the Lt. knee only, then down to leg and become more painful on the ankle, more edema and I could hardly walk especially in the morning. I stopped taking the medication. I would not recommend Lotrel to anybody. My Doctor switched me to another antihypertensive drug. Please listen to your body and speak up to your doctor. M 59 3 months
10/25/2009
 1  High blood pressure The first week I had blurry vision, headache, and runny nose every day. The second week I developed muscle pain in my shoulders, neck, and back so severe I could hardly get dressed. Walking the dog was torture. It is my first day off the drug and the pain thankfully is nearly gone. My doctor said muscle aches were an unusual side effect but let me stop the drug and go back to just Norvasc when I said the pain was interfering with my quality of life. I've looked at forums and it seems others have experienced muscle pain with Lotrel also. F 52 12 days
10/24/2009
 1  High blood pressure One week into taking the meds . I did feel anxiety and nervousness. I have never felt those feeling until I have taken that medince. i also had diahrrea.I started feeling a sensation above my knee where is would start tingling and it would go numb and then start burning after standing for like 10 mins .I have neve had any problems with my legs. Then the second week into in the middle of my thigh started a burning sensation. The third week it just kept getting worse . I went back to my doc and told him he said it was my weight and me walking. So Sept 11,09 I stop taking it. I have been off it for like a 7days . the buring has gone down to a soreness in my right leg but my right foot is very senesative. It very annoying. I do not what it did to me . It has been the worse 1 month experince in my life. I have lost 25 pounds which is great eating right and walking.If it was not for this website and my mother in law I would of kept taking it. Like a dummy. I am looking for a good doctor in M 31 3 weeks
9/18/2009
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 5  Hypertension No side effects. sex hasn't slowed at all and my wife is mad. Came off of Tarka 4/240 because it didn't lower my bp enough. Lotrel brought my bp down lower and the cost is much better. M 55 9 months
9/15/2009
 2  Hypertension I have been on this drug for 4 years. At first I suffered a few reactions light headed and dizzy. They lowered y dose to 5/20 and that seemed to work. I developed ED which my doctor says is common with BP drugs. Tough luck. This year I developed Nervousness, anxiety, tremor in my lower lip, along with the ED. I read the side effects on the web and found all my problems listed as side effects of this drug. Not worth it, I made an appointment to see my PCP next week and I'm getting off this stuff. I have had itching and hair loss also but attributed it to getting older. Now I'm not so sure. I'm seeing several doctors to try and get rid of these problems so far no luck. M 64 4 years
8/28/2009
 1  hypertension I started takinf Lotrel 5-40mg on July 14, 2009. I have almost cough myself crazy. It is so embarrassing to be coughing everywhere I go and people are looking at me wondering whether or not I have TB. I am so tired of not getting enough sleep, because I wake up coughing and I just can't seen to stop coughing. I went to the doctor and he put me on the nasal spray and and over the counter medicine, which was a waste of my money. My husband is so worried about me, and I wake him up at night because of my coughing. I will never take another pill. My BP has been lowered, but it just not worth it. I will go the doctor and try something else. F 60 40 days
8/27/2009
 3  Yes I took Lotrel for about 2-3 months. The medicine did lower my blood pressure, but the coughing was unbearable!!! I would cough throughout the day at work, disturbing my co-workers.. coughing at restaurants became embarrasing..not to mention at night, I would disturb my husband's rest due to the coughing. I had to take cough syrup for hbp just to sleep. My husband was worried that I would become addicted to the cough syrup but I had no other choice! I reported it to the doctor, she put me on Azor instead and I am not to pleased with it either. F 37 3 months
8/25/2009
 5  Hypertension None I've been on the 5/20 dose for almost a year. Very healthy and active, although hypertension runs in the family so started taking Lotrel. Maintaining my BP level very well with no side effects. M 28 11 months
7/9/2009
 1  high blood pressure Took this drug for three days. Had been on Zestril for 10 years never had big problems with it, doctor wanted me to have a water pill combo, but after three days on lotrel i retained water, became flushed, could not do simple everyday things, my whole body ached, bad headache, had blurry vision, just wanted to die Would not recommed this drug to anyone. Stopped taking and back on Zestril having a hard time getting this drug out of my system. Hope i don't have lasting problems because of it.DO NOT TAKE IT WILL KILL YOU F 50 3 days
6/23/2009
 1  blood pressure In 06, I took 3 consecutive rounds of antibiotics which damaged my digestive system and was taking Lotrel 5/10. I had a debilitating fatigue problem and experienced severe energy drain every 2 -3 hrs which lasted for many months. I had to take 3 more consecutive rounds of antibiotics in 07 and my Lotrel dosage was doubled to 10/20 in Dec.08. The severe energy drain came back, accompanied by: exhaustion, an inability to speak normally for 15 months, urinary track irritation and frequency problem. I felt very parched and lost twice the fluid I could drink. I asked several drs if a medication could be causing my problems. This suggestion was dismissed even when they didn't even know what some of meds were. I went to www.rxlist.com ( which gives a more extensive med description than does webmd). Found out that you should not be taking an ace inhibitor(in Lotrel) if you do not have edema which I did not. I then suspected that the Lotrel might be causing my problem. My dr took me off L Be careful if you have to take Lotrel while taking several rounds of antibiotics, It proved to be a horrible combination for me. I have lost 2 and a half yrs of my life, lost my teaching job of 34 yrs due to the extreme fatigue and energy drain. Beware that the ace inhibitor in Lotrel caused me to loose my ability to speak normally. I feel anger towards drs that don't take the time to advise you of possible side effects. One dr actually told me to not look at the print outs the pharmacy gives you. Did not want me to look at a Merke Manual. Told me to throw it away. Yet with this GI dr I got pancreatitis from a drug he gave me and intestinal damage from antibiotics. You know your body. You can take the time to become informed about med side effects. Many drs just rush you through like cattle and push the pills. Some will take the time and listen. F 60 8 years
6/15/2009
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 1  HTN I was put on generic lotrel the last week of Jan 09. At the time I had flu like symptoms, so when the cough started I believed it was a flu cough that was just persisting. After 4 months I knew I needed help. I went to my PCP and he gave me an Advair inhaler, thinking it was a flu induced asthma. Needless to say it was no help. I then went to a pulmonologist and he did spirometry and a barium swallow to rule out asthma and reflux. Both negative. He suggested to me there was a chance it was the Ace inhibitor and called my MD to see if he would ok a change. I started on Azor, which doesn't have the ACE. I have gone through every cough medicine on the market, so sick of cough drops I could scream. It has been two weeks and I am waiting for a good night sleep and an unembarressing meal in a restaurant. I'm curious what the time frame is for most people to get this poison out of our system. June,3,2009 It has been almost a month since I discontinued Lotrel and my cough, etc has almost dissipated. Never knew how grateful I would be for a sound nights sleep. I feel this med has cheated me out of 5 months of my life. Good luck to all of you F 78 4 months
6/3/2009
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