LOTREL Reviews (AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE)

Average Rating: 2.5 (412 Ratings)

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 CALCIUM CHANNEL BLOCKERS ACE INHIBITORS

 Type: Rx Drug

  

LOTREL  (AMLODIPINE BESYLATE; BENAZEPRIL HYDROCHLORIDE):  This product is a combination of two drugs: a calcium channel blocker (amlodipine) and an ACE inhibitor (benazepril). It is used to treat high blood pressure. It works by relaxing blood vessels so that blood can flow more easily. Lowering high blood pressure helps prevent strokes, heart attacks and kidney problems.   FDA Approval Date: 2006-04-11 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR LOTRELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  blood pressure I have this terrible cough I can't overcome. Some days it's dry others I have very thick phlegm. Awful. F 42 1 months
10 mg
5/25/2014
 1  hypertension After taking lotrel for years (12) or more i had a life threatening allergic reaction i had to stop immediately.i have reported this to the FDA .I found 2others in the same situation in different parts of the country.Beware of the benzopril part of this medication F 65 1 days
10/40
7/9/2013
Email
 5  hypertension Have not experienced any noticeable side effects. Before Lotrel, I tried Hydrochlorothiazide, and had intolerable side effects. Lotrel , which is a combination of Norvasc and Lotensin, keeps my high blood pressure under control with no side effects. For me, a very good medicine. M 65 4 months
5-10 1X day
7/5/2013
 1  bp Thanks to Lotrel I now have acquired angioedema. There is no cure. It is random swelling of the head, tongue, lips, eyes, arms and feet. It's been 10 years since I tool this medication and the effects are still here. At the first ER visit acute tongue swelling, I was told by the ER doc never to take Lotrel again. He knew the minute he saw me that I had taken this medication. I would encourage anyone who is prescribed this to run run run as fast as you can. Make another choice. F 64 3 months
30mg 1X day
7/1/2013
Email
 5  I am taking Lotrel 10/20 for HBP I have had nearly every side effect mention, but I didn't know they were side effects. Let me list them. Headache Dizzy at odd times Feel over-all malaise extreme swelling in legs and ankles extreme pain in neck, head, back, and left lower side abdominal cramps coughing, constant feeling of needing to clear throat of nothing pain in hands and feet extremely tired and have a want to do nothing feeling bad and getting worse vision thinning hair, but I have too thick hair anyway I give Lotrel 10/20 Kudos....I mentioned side effects, because everyone else made me more aware that Lotrel is bringing these symptoms on. But here is the kicker....Lotrel works for me, after trying numerous BP meds. Atenolol Norvasc Lisinopril....and others I am fighting with my insurance company to stay on non generic Lotrel.. When I swell I take 40mg of Formosemide with 8meq of potassium, a blue pill, twice a day until the edema is gone. I am on massive supplements because of all my illnesses. I have had these symptoms, but they come and go...most days I am very functionable . I am going to try L-Arginine soon...I LIKE Lotrel now I will monitor myself and my symptoms much more closely. I have been diagnosed.with. Epstein Barr Virus Fibro-Myalgia Chronic Fatigue Syndrome CHF Atrial Fibrillation COPD Rheumatoid Arthritis poor vision these are the supplements I take everyday if I want to feel anyways normal... Aspirin 80mg x 2 Elemental Magnesium 1000mg or 400am/600pm carvedilol 6.5mg x 2 or x4 if I am in Afib. Vit E 800mg x2 up to 2400 If my legs hurt Vit C 1000mg x 4d Fish oil 1250mg x2d Flaxseed 2500 x1d Vit D 5000 x1d Garlic tabs 2500 x2d CoQ10 300mg x1d Resveretol max dose 2xd Cranberry pills 2xd Lotrel 10/20 1xd Centrum over 50 multi V 1xd I am proposing to try more things to get me off meds totally...I believe it can be done. I was LOL, once drug-free! . F 61 9 years
10/20 1X day
6/26/2013
Email
 1  HBP I was an extremely healthy person w/controlled HBP for 3yrs while taking Lisinopril/HCTZ 20/25 & Norvasc 5 - until my Ins Co 'Recommended' I switch my Norvasc to Lotrel 'because they were the same drug', & that my Norvasc co-pay was going up to $50 & Lotrel would only be $25; & they thru in a coupon for a FREE month. After ~10 days of my Lis/HCTZ 20/25 & my Lotrel 5/40, I collapsed & nearly died. At the ER my BP was 56/48, 3hrs later & a BP of 76/58 I was sent home & told I was overmedicated & said I should be fine by the next day. I wish. Each day I started experiencing a different problem, & now have brain damage w/chronic neuro & endocrine issues. EVERY side effect that people have mentioned here, & was listed as a rare possible side effect, I have; & like many others have said, even after a couple days I kept feeling like the drug was still in me. I haven't been able to work since & am considered permanently disabled. That was Amazing how much has & is still, coming out now about Lotrel & its serious side effects. What's more disturbing is the fact that the FDA had previously reprimanded Novartis 3 x's for advertising that Lotrel was a safer alternative to Norvasc & w/very few documented cases of problems; & if you happen to OD, you'd only experience Hypotension. Have you seen the recent product info? I along w/so many others have unpredictable issues on a daily basis that my Dr's can't explain. From chronic migraines & nausea; GI vision, heart, hormone, thyroid & endocrine issues; to rt side tremors, swelling & pain in my feet & extreme fatigue. I believe it will only be a matter of time until some law firm will be courting us to join a class action. EMail me if you'd like to chat. F 44 10 days
5/40 1X day
2/12/2013
Email
 2  HBP extreme fatigue, borderline depression, muscle cramps, joint pain, weight gain, frequent urination Taking Lotrel for HBP. was on 10/20 but later put on 5/40... Was on the heavy side when I started (6'1" - 250lbs) but gained 30 lbs within 6 months of taking the drug. It made me so fatigued and lethargic, I simply did not have the strength/desire for any activity. My marriage suffered because I was suddenly accused of being lazy, which I am not. BUT the drug kept me in such a fatigued state, I was now a burden on my family. The other side effects like the muscle cramps and urination frequency were issues that I could live with, but not the fatigue and depression. I stopped taking LOTREL altogether and I lost 35lbs and my fatigue and depression has "mysteriously" vanished. I'm waiting for a new pill from my doctor...he is upset that I stopped taking the drug, but if he felt like I did while taking the drug he would understand that the life I was living wasn't living at all... M 43 3 years
5/40 1X day
10/2/2012
Email
 1  high blood pressure severe fatique,itching,blisters on arms,wheezing,insomnia,sore muscles flu-like pain,back pain in kidney area,small cough, swelling of ankles and legs, although this medicine does lower blood pressure to normal range for me is about 130/80 it has bad side effects.i was pescribe this medicine about 13 years ago for slightly elevated blood pressure looking back on it now was about the time all my symtoms started i would return to Dr and he would just perscribe something to try to cover up the symtom i would give him.I have been diagnoised for depression,along with several other things that he was guessing at and test of ever thing you could think of. I have been sent to several other specialists and no one could figure it out. I guess its partly my fault also for trusting a pen happy DR to write more perscription instead of trying to figure out all these symtoms i was getting after perscribing this medicine.although they all didnt come at the same time it has been strecthed out over several years. I think it has also caused some kidney damage because i have alot of pain in the area of kidneys and have had some blood from time to time not often.If you are taking please pay attention to side effects they can get bad. M 47 13 years
1X day
9/22/2012
Email
 1  blood pressure At first no side effects, over time neck and back pain, some cough problems, most troubling difficulty in swallowing. At first was just occasional, but is becoming much more frequent and a little scary. F 83 8 years
5/10 1X day
7/14/2012
 1  HBP Had a small stroke after 6months, I'll take my chances with pre-hypertension with out it. If you ahve had a storke while taking this shit feel free to e-mail me. [email protected] This drug made me feel strange most of the time. It seemed inconsistant with each prescripion. I even asked if they were giving me a differrent mfg from time to time. I feel robbed. It takes a freedom of information act request to see how many people this drug has messed up. M 50 6 months
5-20 1X day
5/19/2012
 3  Heart attack August 2006 numbness of upper left arm, extreme fatique, depression, aching of lower legs, headahes, feeling of general malaise, heart palpitations I want to try to stop taking this medication. I have never had a problem with high blood pressure, not before my heart attack and not following my heart attack. F 65 5 years
5-10 1X day
1/22/2012
Email
 5  hypertension None I have been on Lotrel for 12 years and have never had a problem. It helps control my blood pressure and does help alot with my migranes. I have tried other medication, while I was pregnant. But right after I had my child, I had to get right back on Lotrel. F 44 12 years
5/20 1X day
1/12/2012
Email
 3  hypertension My right leg was numb and sometimes painful from the knee to the foot. Right foot would become swollen at times. Started right after I started taking lotrel. My doctor switched me to lisinopril hct. M 49 2 years
10
12/27/2011
Email
 3  HBP Right foot and most of of right leg ... knee level down swells and has some level of discomfort. Otherwise it works in controlling my BP to 120/80 ,.... where others have not worked. Was given Lotrel as "last resort". I guess I choose which is most important ... lower BP or fat foot! M 49 11 months
10/40 1X day
10/2/2011
 2  High bp Caugh,muscle/footpain, leg swelling and itching insomnia I have been on Lotrel for 11 years Dr. increased doseage to 5/20 (from 5/10) in Novemver 2010. Developed left leg/ankle redness and alot of swelling in left leg and a little in left hand. I just discovered these are side effects today I am stopping it now. It Has taken 9 months of a once active life from me. I would rather die of a stroke than live like this. Will contact doctor for a new bp medicine. I was just thinking all these achs/pains was just me getting older M 42 11 years
5/20 1X day
9/1/2011
Email
 2  Hypertension Controlled my pressure with no side effects for 3 years. Now however, I'm experiencing hair loss and thinning, swollen ankles and legs, decreased sex drive, pain in back and joints, severe fatigue. I will be looking for another med soon. F 56 3 years
10/40 1X day
7/23/2011
 5  Severe Migraines Since taking Lotrel 5/10, my migraines have completely seized. I don't have high blood pressure but since Lotrel helps with the blood flow to my brain which eliminates the migraines. This has been the most wonderful blessing ever! Granted, I do have to be careful because it is a HBP medication and I have to treat it as one. F 49 15 years
10mg 1X day
7/18/2011
Email
 1  BP extreme pain in legs/feet confusion,anxiety, swelling in legs ankle /feet. numbness in arms leg, feet, dizzy, upset stomach, vision problems, coughing, body ache and back pain headache, depression F 68 4 years
1X day
7/7/2011
 1  Migraines Basically pretty much all of the side effects others have mentioned on this site. Coughing, muscle aches/weakness, foot pain with some fluid retention, EXTREMELY fatigued, doom like feelings, and shortness of breath and find it hard to concentrate at work. I am being worked up for the fatigue and shortness of breath (have asthma under good control) and I bet it is this drug. I have put a request in to my physician to get off of this drug and haven't heard back from his office yet. I was put on this medicine off-label for my headaches and they have been better but this drug tends to lower my blood pressure and I already have a low blood pressure. Symptoms seemed to get worse when it was switched to a generic brand. Can't wait to get off of it. On a side note I was taken off all caffeine, alcohol, artificial sweetners, and chocolate almost 2 months ago-so they could be headache contributors anyway... Want to get off drug ASAP... F 49 2 years
10/40 1X day
5/19/2011
Email
 2  HBP Swelling in ankles after a month's use. ED still present. Quit taking drug 10 days ago and now BP is 138/70. So what gives? Was on lisinopril, but doctors changed it to Lotrel. M 62 45 days
1X day
3/16/2011

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