METHOTREXATE SODIUM Reviews (METHOTREXATE SODIUM)Average Rating: 3.3 (383 Ratings)Filter ResultsCompare METHOTREXATE SODIUM with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on METHOTREXATE SODIUM: Reviews Summary | FDA Adverse Event Summary
| RATING | REASON | SIDE EFFECTS FOR METHOTREXATE SO | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 2 | Psoriatic arthritis (PSA) psoriasis | Extreme fatigue, regular nausea, stomach pain, diarrhea, IMPOTENCE | Men -I was not warned that MTX could cause impotence. Women be aware it can also causes early menopause. This drug made me impotent. I was been receiving 15.0 mg injections once a week. The side effects were too much for me and I have now gone back to NSAIDS and pain killers. | M | 37 | 15 months | 3/12/2008 | 1 | Psoriatic Arthritis | My brain feels like its shutting down. I have never had a headache before and now I've always got one since starting with this drug. I really don't know what to do. | I was diagnosed about 6 months ago, Sulphasalazine was the first thing prescribed (with Lodine - an anti-inflammitory). Gave me nausea almost every day, stomach pain and diarrhea. Went on to methotrexate 3 weeks ago and I feel awful all the time but just in my head, when I describe it to friends, they say it sounds like a constant migraine. Saw consultant yesterday but he wants me to persevere to see if headaches stop but they're getting worse every day and I keep having to close my eyes all the time. Its hideous, don't take it, I'm going to try and find out about this antibiotic therapy and see if that helps but I'm worried about what the consultant will say. | M | 33 | 3 weeks | 3/6/2008 | 5 | RA | Very tired, weight gain, fluid retention. | Methotrexate has really helped my RA and life is enjoyable now except for the side effects. | F | 46 | 6 days | 2/27/2008 | 3 | rheumatoid arthritis | nausea, muddle headed, fatigue, sores in throat and mouth, irritable and anxious at the same time. | I hope to come off as the new biologic I started takes effect. (ORENCIA) | F | 45 | 5 years | 2/27/2008 | 4 | spondyloarthropathy | fatigue, heartburn, slight nausea, hair loss | Helpful drug, much better than the joint pain and immobility. Taking 12.5mg per week plus 50mg injection of Enbrel. Together, these two drugs are a miracle. **I only take the drugs during flare ups (once or twice a year) as opposed to every single day. | M | 37 | 10 years | 2/24/2008 | 2 | Sero Negative Arthritis | Feel sick for 24 hours after injection of 15mg weekly. Folic Acid has some positive impact. Getting headaches more frequently, short term memory loss, night sweating and very very tired all the time. | Have been taking this drug for 4 months now and I do not feel any benefit in terms of pain. Blood test show that my ESR levels and blood count much better than prior to taking mtx and I am told by my consultant that this is good because it slows the progression of the disease. I will try and continue for a while longer - but not convinced I am doing the right thing. I hate this drug. | F | 50 | 4 months | 2/18/2008 | 3 | Psoriasis / Psoriatic arthritis | MTX 15.0 mg injections once a week. Extreme fatigue, nausea almost every day, stomach pain, diarrhea. | I started to take MTX three months ago because of a flare of both psoriasis and psoriatic arthritis. At the beginning of the treatment, I also took cortisone to help reduce the severity of the arthritic problem (could not walk anymore). After 1 month I stopped taking cortisone as the knee, fingers and toes arthtitis had receded. They have not come back yet, whereas psoriasis has slowly crept back, although to a manageable level. I have to stop taking MTX now as liver damage (from blood tests) is too serious. Hopefully, the next drug will be easier to take! | M | 44 | 3 months | 2/16/2008 | 4 | pyoderma gangrenosum | For the first 2-3 days after dose: fatigue, nausea, low mood, lowered sex drive. After that, none. | I take 50 mg per week (yes, 50) as my condition is difficult to treat. It has made a tremendous difference, but side effects are a problem at this dose. | M | 38 | 1 years | 2/12/2008 | 4 | Juvenile Rheumatoid Arthritis | My daughter has taken Methotrexate for nearly 4 years. She is always sick immediately before taking subcutaniously in anticipation and always sick that night. This continues for a couple of days. She always appears tired, is very forgetful and day dreams a lot. She also has lots of psychological side effects for example: she won't wear certain clothes if that is what she wore when having the injection, she won't go in the room it was given in and takes hours to prepare herself for taking it. Some liver problems have also been identified. | I feel that the drug is impacting upon her whole life. She has taken so much time off from school and it criticised at school for being lazy and not bothering with work. Only after reading others' comments have i realised that she is probably tired all the time and may also be experiencing some memory loss. The drug has helped the arthritus immensely but i wonder at what cost! | F | 11 | 4 years | 2/12/2008 | 5 | pharisis, fibromyolgy | nausa,diarrea | F | 61 | 30 days | 2/11/2008 | 4 | RA | Dizziness, Extreme Fatigue, Occassional Stomach Pain | I still have flare-ups but i am a new patient of this drug | F | 42 | 3 months | 2/8/2008 | 3 | Sero Negative arthritis | At 15mg,Methotrexate migraine headaches daily, profound fatigue, mental dullness,nausea. Unexplained leg and foot cramps at night made sleep awful. | reduced dose to 10mg metho, continued folic acid 5mg daily except day of Metho dose and started weekly Vitamen B12 shots for a month then reduce to monthly. Most side effects inproved, so i'm still in the game to try it out, but is a tough drug to take so far. | M | 52 | 28 days | 1/30/2008 | 3 | F | 22 | 4 weeks | 1/8/2008 | 5 | RA | Worked down from 20mg to 10mg weekly Methxate have been at this for 7 months plus daily 200mg Hydroxychloroquine. Feel absolutely great no side affects and no RA symptoms. It was the Prednisolone in the beginning which upset my intestines. Off that now. Almost tea-total, eat carefully and exercise plenty. | Do I come off or stay on the Methxate, seems its a lottery. If it comes back it could come back worse than before and I believe treatment may be more difficult. If staying on, what silent damage is being done by the Methxate. Consultant is happy to go with whatever patient feels comfortable with. Seems there's not a clear choice to make. (I'm trying to make that choice but need more info). | F | 41 | 19 months | 12/27/2007 | 1 | RA | nausea, being sick all the time (flu like symptoms) | F | 25 | 5 days | 12/4/2007 | 1 | RA | NONE OF THEM WERE GOOD | I stopped taking all of my RA drugs: methotrexate, leucovorin, plaquenil, and my prescription ibuprofen. My kidneys were going to shut down if I did not stop. I decided to try antibiotic protocol therapy. If you haven't read it yet, get the book The New Arthritis Breakthrough by Henry Scammell and read it from cover to cover. I started taking 200mg/day minocycline about 3 weeks ago after I demanded that my Rheumatologist prescribe it. I can't believe that I have been in pain for so long and destroying my internal organs with these drugs for no reason. My pain has decreased to the point where it is almost negligible. The nodules on the backs of my wrists are almost gone. I have only taken the ibuprofen in the first few days as the pain did spike. Now, it is almost completely gone. All this in three weeks. READ THE BOOK. I read it in 1 day. I also came to learn that I personally know one of the subjects of one of the chapters. I never knew she had RA because she doesn't have any of the s | M | 39 | 1 years | 11/29/2007 | 5 | RA | Slight nausea - often the day after taking the weekly dose. Fungal infections of the skin (ankles, legs, fingers) at least once a year, generally during the summer months. Developed a staph infection at the site of a metal plate in my great toe. Had to be hospitalized for surgery to remove the plate and treat the infection. Persistant diarrhea and abdominal cramps - don't know if this is from the metho or unrelated. | This drug has really helped me live as normal a life as possible since I started taking it in 1984. The few times that I've had to stop taking it - usually when I'm having some kind of surgery - my disabling arthritis symptoms return fairly quickly. I know this drug can have dangerous side effects, but on balance taking it has been worth the risks. My doc's have wanted to increase my weekly dosage from 12.5 mg to 17.5, but I haven't done this because I'm worried about more frequent and serious skin infections. | F | 62 | 23 years | 11/25/2007 | 2 | Arthritis | Ihave lost my ability to smell and tthe ability to taste the food. I'm concerned about it. | F | 73 | 2 years | 11/24/2007 | 2 | AS | 10 to 15 mg per week produced dime size mouth sores, dry cough from sores in throat, malaise, dirrahea, hair thinning and loss; folic acid and leucovarin did not help side effects, these bad side effects lasted three weeks after stopping methotrexate, hope my hair grows back | nsaid mobic now helps with pain, switched to enbrel three weeks ago, methotrexate was a poison to me and rheumatologist was slow to make the switch | M | 49 | 12 weeks | 11/24/2007 | 1 | skin rash | liver failure, dramatic weight & strengt loss, sight & hearing loss, pain in hips, no energy - I'd rate this a zero if I could! | Horrible had almost every negative side effect. Could not move from chair for 3 days after taking weekly does and it had no effect on condition. Caused acute liver failure. Die before taking this drug! | M | 43 | 3 months | 11/21/2007 |