METHOTREXATE SODIUM Reviews (METHOTREXATE SODIUM)Average Rating: 3.3 (383 Ratings)Filter ResultsCompare METHOTREXATE SODIUM with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) |
More on METHOTREXATE SODIUM: Reviews Summary | FDA Adverse Event Summary
| RATING | REASON | SIDE EFFECTS FOR METHOTREXATE SO | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 2 | Rheumatoid Arthritis | nausea, diarrhea, migraine, fatigue, vision problems, mouth sores, vertigo | Splitting dose between 2 days has helped naseua. Dr upped folic acid from 1mg/d to 3 mg/d. Dentist called in Peridex mouth rinse which took the mouth sores away w/in a day. Also weaning off of 5mg/d Prednisone. Will give it a little more time. Found that taking anything with aspirin or salycilicate (like Pepto Bismal) causes severe interaction w/ MTX giving me nausea and diarrhea. I don't like it because it tough on your liver and interacts with too many things. Jury is still out on whether or not it's helping. Still having plenty of joint pain. | F | 48 | 5 weeks 15 1X W | 11/28/2010 | 4 | colitis arthritis/ra | TIREDNESS!!! Im in a fog most of the time. Extreme blues two days after taking. Recently hot flushes...could be early menopause. Some nausea | I call these pills the beastie pills. But my life has certainly changed dramatically since taking, couldn't walk more than ten metres, couldn't stand for more than 1 minute. Now no swelling, pain minimal and am able to work again and go up stairs! For me the benefits outweigh the side effects. Recently I have been having more pain so will have to see rheumatologist again in two weeks and perhaps upping dosage. But compared to how I was 6 months ago, I am a different person. I was in a wheelchair when I had to go out! | F | 45 | 4 months 10 1X W | 11/20/2010 | 1 | Psoriatic Arthritis | Extreme nausea, chills, diaherra, weakness. Lasts for 3 and 1/2 days after dose. Can barely walk or bathe myself. | This is nonsense. I'm stopping. I'll try the injection, but that is it. This is not worth it. | M | 48 | 3 weeks 10MG 1X W | 11/14/2010 | 4 | Autoimmune Optic Neuritis | When taking a higher dosage (25 mg) injected, some hair loss. Since switching to oral methotrexate, hair loss has stopped. General feeling of fatigue the day of taking it. I've never had an upset stomach from this medication. Some mild depression, however it could be associated with the prednisone I am also taking. Hot flashes occur, but may be due to hormonal changes as well. | In general, this is a well tolerated drug for me which has helped to maintain the sight I still have left. You need to have your blood checked to make sure it is not affecting your liver (about every 2-3 months). | F | 50 | 2.5 years 15mg 1X W | 11/6/2010 | 2 | RA | very low white blood cell count, recurrent infections | Took for 1 month and got strep throat, treated then restarted. After using for 6 weeks again got strep throat. After treatment of strep, still was not feeling well, was admitted in hospital had gotten pnemonia. White blood cell count was very low due to methotrexate. (My husband has been on methotrexate for 1 year and no side effects, and has kept arthritis at bay with Enbrel.) | F | 37 | 6 weeks 1X day | 11/4/2010 | 4 | RA | Nausea and vomiting, headache, itching, mild hair loss, sadness and weight loss. | My pain has decreased since starting to take Methotrexate. I also take Plaquenil. I feel I am trading one problem for another because the side effects are hard to handle at times. | F | 51 | 4 months 10 mg 2X W | 11/2/2010 | 3 | SLE, APS, MCTD | Stomach pain & bloating, nausea, severe headaches, diarrhea, sever lethargy | I've only been on this a few weeks. I can't tell if my pain is less or that I've got so much else going on I don't pay attention to the pain I'm "used to" Feel like crap all week. Was hoping to feel bad & then have it taper to feeling better every day - not so for me. Also, medication sensitive... | F | 45 | 2 weeks 7.5 1X O | 10/2/2010 | 5 | RA | I DO HAVE A BIT OF MEMORY LOSS AT TIMES AND HOT FLASHES MORE THAN BEFORE. | I TAKE METHOTREXATE ONE TIME PER WEEK AND PREDNAZONE DAILY, THIS HAS CHANGED MY LIFE SO MUCH,I AM NOW DOING THE THINGS I LOVE TO DO SUCH AS GARDENING AND I CAN DO MOST ANYTHING I HAD DONE BEFORE, I AM HAPPY. | F | 56 | 16 weeks 4 PILLS 1X W | 9/28/2010 | 3 | RA | I just started on this and feel very fatigued...like my muscles are just exhausted. 30 minutes on the elliptical felt like an eternity. I also get hot flashes (more than usual), sweat more, and feel out of it--especially the day after I take it. And this is weird, I feel like I want to cry out of the blue. No RA flares though...so that's good. | F | 43 | 2 weeks 7.5mg 1X W | 9/24/2010 | 2 | Rheumatoid Arthritis | Experienced nausea, vomiting, diarrhea and extreme fatigue for approximately 2 days after taking these medications. | The doctor upped me to 8 per week but the side effects were immediate and severe and I cut myself back to 6. I take my meds on Tuesday and by Sunday night I am actually dreading what I refer to as "bad medicine" day. The only reason that I have continued is because the rheumatologist told me it works great in conjunction with a Biologic like Humira which I will be starting by the end of the month. I actually really want off this stuff, it's horrible, but am afraid to stop it because the progressive joint damage is worse. | F | 45 | 5 months 15 mg 1X W | 9/22/2010 | 2 | RA | Diarhea, weight loss, and fatigue. Never helped the RA but was due to me also having Ebstien Bar Virus (EBV) which does not go well with MTX. Was also on Humira same time. Stopped both. | Afterwards, started taking Suflasalizine and Plaquinel which help some, then started Orencia and has help a lot. Went from a 8 pain level, out of 10, to between a 2 and 3. Makes a big difference. | M | 48 | 6 months 10mg 2X day | 9/17/2010 | 4 | psoriasis | Tiredness, mood swings, lower immune system so caught everything going around especially off my kids, muscle weakness and sometimes flu like symptoms. | It did help me so I would definitely use it again if I had another severe flare up. | F | 38 | 4 months 15mg 1X W | 9/14/2010 | 3 | Polymyalgia rheumatica, Sjogren's | at first it was making me feel worse than before, but now I am feeling much better. I take it Tuesday mornings and often need to sleep much of the day, but it has been worth it to me, thus far. I still have pain, but I can tell I am now doing better. | This is a very hard drug to take. It makes many people quite sick. I was sick taking it for the first month. If anything, my depression from chronic illness has lessened. I feel like I can now see some light at the end of the tunnel. I am not sure if improvement will keep up, but I am hoping it will! | M | 60 | 2 months 15mg 1X W | 8/29/2010 | 4 | RA | Mild nausea, which goes away after sipping ice cold aloe juice. Nausea seems less of a problem each week. | Have had RA joint pain in fairly frequent flares since May 2009, and was diagnosed with RA in Feb. 2010; RF, ANA, and CPP all positive. Pain was severe (7-10 on 1-10 scale) in shoulders, wrists, and hands, especially. After 3wks on MTX, flares can't seem to get much thunder - frequency, duration, swelling, and redness of flares are down 50%+, pain 3-4 at worst. I take Indomethacin 50mg if there is any inflammation to minimize erosion, but don't need it for pain anymore. Vicodin was required for relief from shoulder flares before, now untouched for several weeks. I have more energy than before. I think the pain and disease process were the cause of my extreme fatigue the past year. I'm hoping for remission. Everyone reading with AI diseases: have your Vitamin D level checked. A lot of us are deficient and don't know it. I was. | F | 50 | 2 months 7.5mg 1X W | 8/21/2010 | 5 | rheumatoid arthritis | still tired-often stay in bed on Saturdays after taking meds:5 pills Fri. night and 5 on Sat. am,some nausea, weakness. Just increased to this dosage in July. | In May was completely off of predisone taking only Methotrexate, but in June started having some recurrent pain, hips, hands, shoulders, feet. Methotrexate dosage to 25 mg in July. Pain still present, but not unbearable...still a miracle drug for me, compared to before methotrexate. | F | 48 | 7 months 25mg 1X W | 7/28/2010 Patient History | 5 | sero-negative R/A | no side effects | Did not work as well for me w/o Arava 20 mg daily. Blood labs have always been fine. Some gastro problems from time to time. Tried once to get off both drugs and flared terribly. The two must work together for me. | F | 65 | 15 years 15 mg 1X W | 7/23/2010 | 4 | psoriasis / pa | Ridiculous fatigue, fever, night sweats, headache, nausea and upset stomach | I still feel somewhat tired and get headaches, but the other initial side effects have gone away. Was depressed because my skin was so bad, and now it has improved greatly and I have less pain in my joints but I feel even more depressed. WTF? Also I have vertigo and some lymph nodes that are slightly enlarged and never go down. On the bright side, I'll be able to wear shorts and a tank top when I kill myself! It's a great drug but there's a lot of robbing Peter to pay Paul involved. | F | 37 | 2 months 10 mg 1X W | 7/11/2010 | 5 | RA | Fatigue, upset stomach, mouth sores, elevated liver enzymes | F | 40 | 1 years 10 MG 1X W | 7/8/2010 | 4 | mixed connective tissue disorder | Take on a Saturday afternoon. Wake up middle of the night with a bad headache. Sleep most of Sunday, feel "spacey" all day and feel like I'm coming out of the fog by Sunday night. Am going to begin to take it Saturday AM and see if I get more of my Sunday back. Hate missing a day out of a weekend. | Has helped greatly with foot joint pain. Took 4 weeks to notice the change. | F | 55 | 20 1X W | 7/4/2010 | 4 | palmo-plantar-pustulosis and PA | At higher dosage, I had dry mouth, queasiness, tiredness | Dosage is actually in two units per week: 3 tablets (2.5 mg each) on Tuesday, and 2 tablets on Saturday. Folic acid (1 mg) every day. I also gave up most gluten food, follow the no-alcohol requirement, and minimal sun-exposure. I have low vitamin D levels and am supplementing to build that up. The MTX was a big help with the palmo-plantar-pustulosis form of psoriasis and PA, but I got several flu-like diseases in winter, despite inoculations. | F | 59 | 16 months 6.125 2X W | 6/25/2010 |