PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)Average Rating: 2.8 (628 Ratings)Filter ResultsCompare PRISTIQ with similar:
Type: Rx Drug
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Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first). Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 |
More on PRISTIQ: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR PRISTIQ | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 2 | for anxiety/mild depression | extreme anxiety and agitation especially in the morning. 1st week fear of being alone, headache and nausea too for 1st week. | I'm not sure if I will continue this drug, if the anxiety and fear doesn't subside. It's been a roller coaster ride from day one. the daytime seems ok for a few hours but outside that anxiety pulses through my veins. Ativan is the only way I can go to work. For people whom had severe anxiety before, be prepared to feel even worse. It's scary. I will try for 4 more days and that's it. Doctor says 3 weeks is needed for pill to be effective. Good luck everyone. | F | 42 | 18 days 50 mg 1X day | 9/17/2011 | 2 | MDD, PMDD | Extreme sedation when taking it in the morning, insomnia when taking it at night. Felt zonked out most of the time. Near complete loss of libido. Blurred vision. Mild nausea and fluctuations in appetite. Heart palpitations. Constantly felt overheated, like I had a fever. | I'm extremely sensitive to side effects from most of these medications. I did notice an improvement in my mood, but the side effects did not go away with time on this drug. I was encouraged by the fact that I was able to take a full dose for almost three weeks, though--I'm usually not able to stay on a quarter dose of anything more than a day or two! Also, it really did reduce the symptoms of PMDD significantly. Too bad the side effects didn't go away. | F | 46 | 18 days | 6/7/2009 | 2 | Depression | Sleeping all the time , no will to do any-thing , didn't feel like even taking a bath!! Better since I stopped taking it, I only took it for 2 1/2 weeks. Man , what a nightmare. | I think this might work for some-one , but not the general population of depressed ( and I mean depressed , like it's life for us , dawl , type folks ) | F | 42 | 18 days | 12/2/2009 | 5 | depression | Side effects, just one, dry mouth but not too excessive. | This has been a miracle drug for me. I experienced a "lift" immediately upon taking it. I was having trouble being motivated to even take a bath and every day at work was like climbing a mountain. I have my energy back and feel happy again. I have been on other medications and I have never experienced anything like this one before. It's a miracle drug for me. | F | 56 | 20 days 25 mg 1X day | 3/10/2012 | 3 | Depression anxiety and chronic pain | My doctor convinced me to try anti-depressants again because I have lost another job due to chronic pain and depression. I started feeling results right away. Good and bad. I have been feeling a surge of motivation which is helping against the dissabling feelings of depression. I have never been so productive! However, since day one of taking Prestiq, I have been experiencing persisting heartburn, insomnia, inability to climax (loss of sex drive which was NEVER a problem before)and a slight increase in anxiety. (nothing like the anxiety I felt with Cymbalta-difficulty breathing)I have been taking the med in the morning. Maybe I will try to take it at bedtime. The motivation has been great but I have been experiencing severe heartburn all day long since day 1. Also, I wake up at 3AM-4AM every night since taking Prestiq! This is odd for me because I usually sleeped like a log. It's 4:30AM as I am writing this!!! Waking up with an increased heart rate. The bouts of productivity have been | I would like to be able to continue this drug without the side effects because I have been laughing more, feeling more excited about life and more productive than ever! It's a toss up!!!!!! | F | 30 | 20 days 50mg 1X day | 11/17/2010 | 3 | Depression, Anxiety | Crazy dry-mouth for first 10 - 12 days. Loss of appetite (may be due to original condition). @ 15 days mostly normal, though occasionally get weird burning sensation on random patches of skin for few mins - 1/2hr at a time. Yawning. | So far so good. Takes a while to work so I'm trying to feel it. It's my first diagnosis for depression. I've been called high-functioning and up-beat during the last three years while I was depressed. | M | 43 | 20 days 50 mg 1X day | 6/7/2010 | 1 | Depression | During it's use, I could not easily distinguish any, since I was taking two other drugs for on the same days (2x Adderall for AM & noon, and 1x Clonazepam for late PM). But after I quit taking it (about only 20 days later), I experienced a major-heavy withdrawl that induced even heavier feelings of depression, anger, and distress than I ever had before. (I really can't recall the amount, but I think it was 30mg). | Withdrawing from Pristiq was VERY BAD. Pristiq didn't do much for me within the 20 days that I took it, so I just stopped cold-turkey. Bad idea! About 1 day after I stopped taking Pristiq, I could not help but to feel deep despair along a worsened form of my depression. Contributions of these bad feelings were mostly because of an unwanted divorce that occurred 4 months prior to starting Pristiq. The physical withdrawl was deep crying for nearly 30mins straight, a need to curl up in the fetal position, and body trembling. During withdrawls (which recurred on 3 more days) were incidents of sudden screaming out at the top of my lungs that were of: grief, anger, despair, remorse, anguish, among others... It's scary to know that such a drug had forced these emotions and feelings out from inside of me in such an unusually powerful and quite disturbing way. I advise NOT to take Pristiq if your depression is not that bad, and to try something safer that has more history. It's better to try something that's safe and proven effective, than taking a substance that has the potential to make an already bad situation 10x worse, and that can potentially induce or increase suicidal thoughts or motives. +Your better off temporarily very sad, then forever dead. !++++ Seek safer alternatives for God's sake! | M | 29 | 20 days 30mg 1X day | 11/8/2010 | 1 | Bipolar, depression, rapid cycling | Severe and acute florid MANIC episode on this med. I do not recommend at all for Bipolar l. Be VERY wary of the noradrenergic effects! Florid dreams. Have now stopped and substituted an SSRI without the the noradrenergic effect. Make sure you are under specialist med supervision during any *changeover*! | Do not take ANY alcohol with this med. From my own experience, I feel this med should be contraindicated for Bipolar_1 patients. I experienced a brief but heightened frightening manic episode on this med. Other meds i am on included: Seroquel 350mg/day, Lamictal 200mg/day, Diazepam prn.... I feel it is the noradrenergic effect that led to the acute manic episode. My later switch to an SSRI without that NA effect,namely citalopram-GA. (Celexa) helped me so much more,, as well as having a beneficial effect on my GAD. My warning is that desvenlafaxine and Bipolar 1 do not seem to agree. At least >> that's my personal experience. | M | 54 | 20 days 25 1X day | 12/17/2012 | 4 | depression/anxiety | sexual side effects, inital loss of appetite | This drug is similar to Effexor. I feel much better, more even-keeled, and can laugh. No more panic attacks. However, it flattens me out a bit and does not help with motivation. I may add an ADD med for that. Biggest concern is weight gain; and though I lost weight at first, it is too early to tell about that. | F | 44 | 21 days 50 mg 1X day | 2/15/2010 | 1 | Depression/Anxiety | Was great during the first week and didn't notice any side effects during week 2 BUT then week 3 came and I want no more! I have been having the brain zapping and feeling dizzy and really off balance. I feel out of control a lot of the time and depression and anxiety seems to have worsened. | F | 39 | 21 days 50mg 1X day | 10/6/2014 | 1 | severe down mood. sweating. sexual dysfunction. no appetite. no rest. | M | 56 | 21 days | 2/7/2009 | 3 | Emotional disorders/Depression | Hard to fall and stay asleep; awoke 2-3 times per night as if someone turned a switch on on me. Discontinued it, it got worse than before. Dizziness in its prime form. | Pristiq generally helped me stay in emotional balance; well, somehow. It has/had an effect of a box ring. My evil and bad are in diagonal corners ready to start a fight and Pristique keeps them in their corners. It doesn't eliminate them, it just delays or cancels the fight. Nice. However, I am afraid of becoming dependent on this drug. So, I discontinued taking it while having my period (thinking I am on safe ground for a few days or so). Oh, my God! First day I got so dizzy, that I fell on the floor and had to stay there for a while until the Earth was safe to walk on it again. Completely dizzy, not like a hang-over dizzy, but like you feel the gravitation and need to hold on to something. I was standing up only so I can throw up and then was lying on the floor again. At work, in my office. Today is the 4th day and I am still dizzy. However, I had a cafe latte to center myself somehow and be able to perform my tasks at work (haven't had coffee in 2 years). And I cried a river - all these 3 days; can't stop from crying. The evil jumps from the corner and makes me say mean things to my child (I called her Stupid - for the first time). so, Pristiq? I don't know. It does something terrible to my brain. And I need my brain for another 3 or 4 decades. | F | 40 | 23 days | 11/12/2009 | 3 | MD, anxiety | yawning, headaches, dry mouth, extreme fatigue/excessive sleeping, fidgeting, intense but hard to reach orgasms, panic attacks, head spins, biting tongue in sleep (so weird), zero emotion at times, vivid dreams, decreased appetite, rapid heartbeat | I'm only 3 weeks in and the side effects are starting to disappear except for the yawning, mild anxiety and rapid heartbeat. I definitely noticed reduced side effects when I'm eating healthier. but I'm nervous to continue because of the wd symptoms. does anyone know if I could go cold turkey after this short amount of time? hasn't really helped with depression yet but I have noticed more energy. I think I'm better off not taking Pristiq. | F | 32 | 24 days 50 | 12/5/2019 | 1 | Depression | I took this medication for depression. I had a terrible time tolerating 50 mg. of Pristiq. My side effects were leg cramps, memory loss, dizziness, increased depression, head zapping every time I moved my head (this was not present every day - I experienced this on a few different occasions, sometimes lasting up to two days), and a feeling of agitation. | I had been on Effexor XR 150 mg. before but experienced some weight gain so my doctor suggested that we switch to Pristiq. Other than the weight gain the Effexor was working well for me. Needless to say I am back on the Effexor as of yesterday. I never write comments but thought it was important to share my negative experience about this drug. My doctor really pushed me to try this and seemed very shocked that I had any side effects. I was relieved to find this site two days ago and to see that I'm not alone. I'm sure this drug will work miracles for some, but it doesn't work for everyone. You just have to keep trying until you find the one that works for you. Good luck! | F | 45 | 25 days | 10/21/2009 | 5 | Depression | Mild hot flashes and decrease in appetite, a good thing for me. | Now I'm finally happy again. Love the stuff. And because my appetite has decreased, I'm even losing some weight I've been trying to get off for years. I've noticed my vision has gotten worse, but I don't know if this is due to age or the drug. I am taking 50 mg of Pristiq and 450 mg. of Wellbutrin XL. | F | 60 | 28 days | 4/11/2009 | 1 | Major depression | Insomnia, cold sweats | No help at all | M | 54 | 28 days 100 MG 1X day | 9/21/2022 | 5 | Depression | I was told to take it in the morning but it made me so sleepy in combination with other meds that also cause sleepiness so switched to night. End of problem. Slight headaches, slightly blurred vision, very dry mouth. Itchy skin which may or may not be related to the drug. | I was prescribed this because the medication I take for bipolar wasn’t enough for the down side. Effexor was ineffective entirely. Within a week I was feeling better. After 30 days I haven’t had a single bad episode of depression. The side effects are worth it to me. | F | 60 | 30 days 25 MG | 10/23/2020 | 5 | depression, ocd | None | Very smooth transition from Effexor XR. | F | 35 | 30 days | 9/17/2008 | 5 | Depression | Minor sweating first 3 nights, lower libido | This is the best drug I've tried, and I've tried most SSRI's, Wellbutrin, and Trintillex. The feeling of 'dread' is much lower, and my head feels calmer. Virtually no side effects. There is a lower libido, but I've experienced that with all drugs, except for Wellbutrin, which was not very effective | M | 42 | 30 days 100 1X day | 12/12/2017 | 5 | major depression | some sweating, sleep is difficult but appropriate to times taken | F | 61 | 30 days 100 mg 1X day | 4/22/2010 Patient History |