PRISTIQ Reviews (DESVENLAFAXINE SUCCINATE)

Average Rating: 2.8 (628 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

PRISTIQ  (DESVENLAFAXINE SUCCINATE):  Desvenlafaxine is used to treat depression. It may improve your mood, feelings of well-being, and energy level. Desvenlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 2008-02-29 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken from shortest to longest duration (reviews with no time reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR PRISTIQCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Switched off zoloft Weight gain, mood swings, lack of energy, angry, loss of memory F 35 3 months
30 mg
2/21/2012
 1  Anxiety Disorder, Depression Intolerable anxiety, three months cringing in bed,18 months later and eight medications to bring it down to "tolerable". I included some "essential" reading in my comments. Best of luck ... ... After I went off Effexor (375mg) my depression returned, and my "high reputation MD" insisted on 100mg of Pristiq (aka "Effexor or steroids"). After I was in "severe anxiety", he raised it to 275mg ... ... and I wound up "cringing" in bed for three months, while he kept insisting the two were identical (I'm convinced there was a kickback). After some research, I switched MD's, went on Effexor, and we finally found the “eight” medications that “reduced” the side effects to “tolerable”. It’s now 18 months later, and I still feel like I'm plugged into an electric socket. If considering, or on, Pristiq, essential reading, "Top 5 Reasons to Forget about Pristiq" by Dr. Carlat, a prof atTufts Med School, (www.carlatpsychiatry.blogspot.com/2008/03/top-5-reasons-to-forget-about-pristiq.html) … ... the lawsuit at www.i.bnet.com/blogs/pristiq-complaint.pdf for (great info on Wyeth's future without Pristiq) … ... and google “lawsuit pristiq”. BTW When I asked the orig MD why he insisted on Pristiq, “because it has fewer side effects”. The SOB was white and shaking after I said “you %^&, I didn't have any side effects with Effexor. If it were me, I’d insist on Effexor (and don’t give Wyeth your money, get the generic). M 57 3 months
275 1X day
6/14/2011
Email
 5  Anxiety At first it was a rough go switching from Vibryd to Pristiq, but I think it was because the Vibryd was not at the levels I needed. Therefore I was already at a low and needed to come off of Vibryd and build up the Pristiq. The first 2 weeks I experienced some weight loss (yeah), an internal vibe that drove me nuts, not quite the jitters though, slight headaches, naesea. i stuck it out though and am glad i did. I can't say i have too many side effects now, except short term memory loss. I find I am literally searcjing for thoughts that are mashed up in my head, that I know are there but cannot bring them to mind!! Hence why i ended up here. All prior side effects are gone except the memory issue I do not have any complaints with Pristiq, except tbe cost. My prescription plan change with the new year and $150 a month sucks! F 42 4 months
50mg 1X day
1/20/2013
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 5  mild bi-polar disorder; menopausal Initially experienced mild nausea and insomnia, which got better when I switched to taking it early in the morning. It wears off quickly if you take it take it more than 24 hours apart. Pristiq has been a good fit for me. Have been able to stay focussed, have less anxiety in day to day situations (am a lawyer who works with a lot of other type A personalities, which can get a little crazy), generally feel like my mood is balanced and that I am happier. Has also helped with menopausal symptoms. F 46 4 months
100 1X day
4/10/2011
Email
 5  Anxiety Disorder None Was on Lexapro for almost a year, but went off due to sex-drive issues. I lost 2 lbs when I switched to this drug and it helped my anxiety even more. My sex drive improved mildly, too. This is a fabulous medication and I'm very satisfied with it. F 25 4 months
50mg 1X day
5/9/2010
 5  depression Headaches and fatigue first 2 weeks. Small weight gain. I am very happy with Pristiq. I feel happy and content. Nothing bothers me too much. I tool Welbutrin before and it caused heart palpitations. So far so good on Pristiq. The only thing I wish it did was give me a burst of energy. I have gained 10lbs. While taking Pristiq but it is because I feel so happy and comfortable. I just don't care! My mentality is like "yes, I would love dessert! Life is great! Life is about eating dessert!". I wouldn't mind this if I wasn't already overweight. F 41 4 months
50mg
6/25/2016
Email
 5  Anxiety Without food: Headache and nautious With food- none I started on Pristiq after being off and on anti-depressants for my depression and anxiety. I was depressed only due to post-partum, but the anxiety was constant. I always had a tight feeling in my throat and could not make it stop. All day long... Pristiq is the only drug I have found to stop the tightness, but with very little side effects. The nausia is the worst... Have noticed some hair loss (when I brush)and night sweats. Other than that, I feel better than I have in several years. Feel like I'm ME again.... I recommend this.. but really, it's all on how your own personal body accepts the med. You would have to try it to see if it would help... I wouldnt go on all the comments much.. everyone is different. F 31 4 months
7/24/2009
 5  BiPolar Disorder sleeplessness Have been on Pristiq for 4 months in combination with Zyprexa and Seroquil. I am the most stable I have been in 10 years. I started on 100mg but was increased to 200mg which works for me. The sleeplessness is handled by taking them in the morning. F 48 4 months
5/25/2009
 5  Major Depressive Disorder None I take 50mg Pristiq with 300mg Wellbutrin XL and 15mg Abilify. This combination works very well for me with minimal side effects. I am my old self. 48 4 months
5/5/2009
 4  Depression nausea, frequent yawning, sleep issues, de-sensitized genitals Had been on Effexor years ago and had very serious withdrawal symptoms so I didn't want to take that again. Pristiq has definitely helped me with the depression (went from 50 to 100mg). The nausea and sexual side effects have gone away, but I am still yawning a lot and am CONSTANTLY fatigued. I can go to sleep without issue but I wake up all night. I can go right back to sleep, but all I'm getting is interrupted sleep-- nevertheless, I don't want to change meds because this has def helped my demeanor. CATCH 22!!!! would recommend, though. F 36 4 months
7/2/2009
 4  Depression, Anxiety, PTSD, OCD Tired throughout the day regardless of sleep hours. Within the first week I noticed a considerable difference in my level of depression. After 4 months however it seems to have lost some of its effectiveness. F 39 4 months
7/15/2009
Email
 4  Depression, Severe Anxiety Drowsiness, Problems focusing . . . both lasted about three weeks, then lessened. I do not notice either anymore. I moved to this after my insurance dropped Cymbalta. Pristiq seems to be working sufficiently [in conjunction with other medications]. However they cannot singularly do with Cymbalta did. F 22 4 months
12/13/2009
 4  Severe Depression Anorgasmia,Apathy,and Weight gain!!! Pristiq 50mg has been wonderful at relieving my suicidal ideation and depressive mood!!! I felt relief within a week of taking the Pristiq. I also started taking Pristiq with Wellbutrin XL 300mg. I already take Abilify 10mg and Klonopin .5mg at night. I thought this was going to be my answer until I have put on 20 lbs in the past 4 months with no changes in my lifestyle except the fact that I started taking the Pristiq and Wellbutrin!!! I plan to taper off the Pristiq very soon, like taking it every other day for a week and see how I do??? Wish me luck and pray for me :-) F 40 4 months
50mg 1X day
5/30/2010
Email
 4  Anxiety and Depression Increased tiredness. I will sometimes have day naps that last up to two hours which i don't like. Aside from this, however, no other side effects. This drug has been the best I have tried. I've also taken Paxil and Cymbalta and both of those made me extremely tired and lethargic, so this is an improvement. Has lifted my depression and my anxiety is manageable. I feel good. F 24 4 months
100 1X day
4/12/2010
 4  depression and anxiety insomnia, increased energy and alertness, weightloss the initial week was very difficult, extreme stmach cramping and dizziness however after that i felt very well balanced, panic attacks had decreased and there were minimal side effects other than loss of appetite and insomnia (but i was tired). coming off the medication proved the most difficult with vomiting, mood swings and all around irretability but i found if gradually weaned myself everything was ok. uncertain if i should go back on them andhence i'm here... F 22 4 months
50 1X day
3/12/2010
 4  anxiety loss of sex drive, took care of anxiety tho. Have tingles in legs and side of head sometimes. Is that brain flashes? feel sleepy often and when I give in, it's a 2 hrs. nap. Feel like a giant pulse goes thru me when I am standing still. F 54 4 months
100 mg 1X day
3/15/2010
 4  mood, depression, anxiety I have been taking pristiq for 4 months and it has helped and I have even lost a little bit of weight. It's the first medication that I have took and not have suicidal breakdowns. I do have anger problems. I can handle the kids great but I get very angry with my husband. Plus, I do get migraine's with it. F 31 4 months
50 mg
10/15/2012
 4  Depression I struggled with anorexia and depression last year, so my doctor prescribed pristiq. It started working after a week or so, and over time i did feel better mood-wise, although I still did have bouts of anxiety. I put on weight seriously rapidly on this medication, although I needed to, but it's very excessive. I can't orgasm on this medication. It's been about a week now that I've quit cold turkey from this, and have been really really nauseous and my eyes can't focus properly. I hope to be completely independent again because I know i can help myself now. F 16 4 months
50 mg
2/3/2012
 3  Fibromyalgia, CFS feeling jittery in the beginning, slight stomach upset/ all disappeared after a couple of weeks, restless legs got worse I started taking Pristiq after weaning off Prozac, which had made me tired and emotionally flatlining. 3 years ago I started taking Cymbalta after being diagnosed with Fibromyalgia, and it helped a great deal. I really loved it. Then the poop-out came... :( I started taking Pristiq with my hopes being high. I don't really have any significant side effects, except maybe my restless legs worsening. I probably would have dealt with that side effect, but the problem is that Pristiq might be working well for depression and anxiety but it doesn't do ANYTHING for Fibromyalgia related pain. The pain came back with a vengeance after being off Cymbalta. I have just started weaning off Pristiq and giving Cymbalta another shot. If that doesn't work out then I will ask my doctor for Savella. F 42 4 months
50 2X day
12/6/2011
 3  depression grinding teeth, sweats, headache, nausea F 23 4 months
50 MG 1X day
5/4/2010

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