PROGESTERONE Reviews (PROGESTERONE)

Average Rating: 2.2 (522 Ratings)

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 ESTROGENS PROGESTINS INFERTILITY

 Type: Rx Drug

  

PROGESTERONE  (PROGESTERONE):  Progesterone is a type of female hormone (progestin). This medication is similar to the progesterone that your body naturally makes and is given to replace the hormone when your body is not making enough of it. In women who are not pregnant and not going through menopause, this medication is used to restore normal menstrual periods that have stopped for several months (amenorrhea). Progesterone is also used as part of combination hormone replacement therapy with estrogens to reduce menopause symptoms (e.g., hot flashes). Progesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. This medication is not for use in children. Progesterone must not be used to test for pregnancy.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on PROGESTERONE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROGESTERONECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Irregular, heavy cycles, cramping Bloating and cramping (not on my period); depression, sleep disturbances I was only taking half of the lowest recommended dose--after reading Dr. Lee and others, I thought it would be beneficial. The first couple of days I was fine--even thought i was sleeping better. I just realized today that since about the third day I was on the cream, I haven't felt like myself at all. I threw it out tonight after stumbling across these comments. I'm glad I did--I thought I was going nuts as the information I read indicated there would be no side effects at such a low dose! F 41 6 days
20MG 1X day
3/3/2010
 1  menopause I have become more depressed, terrible diarrhea, weight gain, starving all the time. gained 20 ibs all on my stomach. Dr.Lee should have a chapter in his book about the possible negative side effects. F 48 1 years
1X day
2/20/2010
 2  Uterine Lining Buildup I was given progesterone because I am using Vagifem (vaginal estrogen) and the doctor said I should use progesterone once a year to keep the uterine lining from buildig up (unopposed estrogen). I took it and what a mess! I took it for 2 weeks and my breasts became painful, back ache, hemorrhoids, headaches, water weight, UTI....all the things you get when you are pregnant (because it is the prenancy hormone). I felt horrible. It then goes away after my cycle but has returned each month for the past 4 months each time my cycle is due. Each time the symptoms come back, they are less than the month before. All this from 2 weeks of progesterone (pill form). I hope it gets out of my system soon. M 48 14 days
100mg 1X day
2/18/2010
 2  saliva test showed low progesterone I am 46, had my tubes tied. Excellent health. Exercise 5-6 times/week. Used to be size 4. Last two months I have been frustrated with 15lb weight gain, bad cramps with punctual menstral cycles, breast stay sore and are larger cup size. I have a fat belly now. Used to be size 4 and now I cannot find clothes that fit me right because I am built like a pregnant woman. Size 8 maternity is probably what clothes would fit. Despite being 46, tubes tied, monthly timely cycles, I thought I was pregnant. Negative. So I am finished with this Fad, Craze. Since out of 5 women i know(including myself)all had the saliva test, all with the same low progesterone levels, all put on progesterone. 3 of us gained belly fat the other 2 are just getting liposuction(some new type of liposuction-done by the same doctor prescibed biodentical hormones)Another craze I guess. I quit 2 weeks ago and lost one pound so far. I am hoping for my old self again. Is it the new FAD/CRAZE? F 46 9 months
20MG 2X day
2/17/2010
 1  doctor recommendation Acne, severe leg cramp My naturopath recommended Progon B because I am taking Vagifem estradiol suppositories to combat atrophic vaginitis. The Vagifem helps a lot, but my Naturopath said that I should not have estradiol alone, I need progestin too. But I stopped immediately, the leg cramps were severe and the acne was too. It was a dramatic reaction. F 56 2 days
1X day
2/13/2010
 3  Thick uterine lining/low progestero I have been on progesterone now for 5 days...I was wondering if anybody else has had trouble with being cold and unable to get warm. Or after that goes away then my hands get hot and red. I am feeling slightly nauseated also. I also wake up several times at night wide awake. I don't know if this is from this medication. F 45 25 days
10mg 1X day
2/5/2010
 5  post partum insomnia None! I finally got some sleep. It sounds like progesterone cream (I took progest) works for some, but really sucks for others. Seems like a gamble. It definetely worked for me though with no side effects F 32 14 days
2/2/2010
 2  Change from conjugated estrogens! The first 2-3 weeks were fine, then I started having hot flashes, couldn't sleep, weight gain, bloating, urinary problems (bleeding), feet & hands swollen, irritable, lazy, dizzy driving, no concentration, etc., thyroid problems I am a 52 yr old that had a complete hysterectomy 5 years ago and was on conjugated estrogen, so with the help of my doctor I have been using Progest along with Triest for 1 1/2 months now thinking that it was time I switched as you are only supposed to be on the CES for so many years. The first two weeks were fine, then I started having the worst hot flashes, I have never had them before, it was terrible. I also have fibromyalgia so any little change in medications sleep patterns really upsets me and puts me into a major spin! Then I couldn't sleep. I was taking 1/4 tsp of 6%, so they told me to increase it a bit, I started getting dizzy when driving, gaining weight, 2-3 lbs. at first, irritable, freezing cold. Then I had to adjust my thyroid meds and I still cannot get them right. The pharmascist told me to stop using the progest for 10 days my doctor told me just to decrease it, next day I got up and my stomach was so distended that I couldn't get any of my pants on, I have gained at least 4 inches at waist. I also can't pee and when I do there is a bit of blood on the tissue. I can't get anything accomplished because I can't concentrate. My feet were so swollen I couldn't even see my ankles and my hands are still swollen so that I can't get my wedding rings off and can't wear any of my other rings. My right hand is tingly and red, I can barely bend my fingers. I think I am going to stop using this, I don't know what else to do. F 52 1.5 months
1/24/2010
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 1  Combat excessive estrogen After having a hysterectomy just over a year ago, I was put on progestrone cream with 20 mg twice a day without any hormone tests to see what I needed. I can't think properly now, bad headaches and have bloated up and gained some much weight that no clothes fit. I don't want to leave the house. What happened to me? I am a fit and active person who is 5'3" and weigh 112 lbs before hyster. Now I weigh 127 and gaining. I am down to under 1,000 calories a day with working out for at least 3 hours and nothing is stopping this horrible weight gain, bloating and feelings of depression, headaches and an earache. Why is a doctor prescribing this stuff without even testing me to make sure I needed it or could even handle it. Don't let a medical doctor who doesn't care, prescribe this stuff. F 48 20 days
1/16/2010
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 1  Birth control while nursing unexplained weight gain After my second pregnancy I began to gain weight, while breastfeeding...and keep thinking that it should be going in the other direction. I eat healthy and do not lead a sedentary life. After reading all of the postings I am NOT going to take the progesterone pills any longer, we'll just practice some other form of birth control...and hope that I can begin to lose the weight. F 34 4 months
1/16/2010
 1  spit test showing low progesterone my side effects were: insomnia, anxiety, irritable, cortisol type weight gain at waist I took the progesterone cream, just a small amount and had horrible side effects. I think health care providers prescribing need to be aware hypersensitivity of even bioidenticals. I think my insomnia was stress related and this made it 10 times WORSE!!! F 35 3 days
1/14/2010
 3  saliva test low prog/high estrogen Not aware of any side effects that are a problem. I have autoimmune thyroid so many of the side effects described by some are issues I've had which some doctors relate to the thyroid. Depression, no libido, heavy periods, pain, etc. I did the complete saliva/blood profile from ZRT labs. I didn't want to make a decision on using anything without having proof of a low or high lab count. Progesterone was super low while estrogen was super high. Hopefully after a few more months it will have helped. I got my progesterone from a compounding pharmacist. I use 20 mg. progesterone to a one gram (about 1/2 tsp) of cream on days 12 through 25 of my cycle. Given my labs it has to do some good at balancing my levels. F 54 2 months
1/13/2010
 1   Insomnia (waking up after 4 hours of sleep with hot flahses), anxiety, depression (crying all the time), moodiness. Would rather be dead... DO NOT TAKE THIS WITHOUT READING POSSIBLE SIDE EFFECTS. DRUGS AFFECT EVERYONE DIFFERENTLY!!! F 35 3 days
1/13/2010
 5  menopausal symtoms I am applying natural progesterone cream ( 1/8 tsp 2X per day for 21 days). It has alleviated my hot flashes, sleeplessness, headaches and has restored my libido. As for weight gain I can't tell. BEFORE I started with the cream I had gained 20 pounds and have not gained more. A lot of the comments here are about synthetic prescribed progesterone which is extracted from female mares and is very strong. Your site should differentiate. F 54 3 months
1/12/2010
 1  ovarian cysts, endo, migraines, pms sleepiness, grogginess, irritable, unmotivated, depressed, confused, extreme anger, only positive side effect is increased libido! But my husband is going to divorce me, and I'll have no one to have sex with if I don't quit yelling at him for no reason!! Someone listed mental "swishiness", and I so get that! I have that too! I feel like my brain is sloshing around in my head--driving is hard--hard to focus. Wow--I can't believe so many people have experienced what I have on bioidentical progesterone cream! My dr prescribed it, and at first I felt more relaxed--slept great too. But into the 2nd month I started having nighttime panic attacks and nightmares. I also feel so groggy and foggy all day. I have waves of a feeling of well being and comfort, and it can quickly turn into unprovoked rage! What is that about?! I keep picking fights w/my husband, and we usually never fight. I have crazy spells of crying--I just feel SO hormonal, and I still have to used Imitrex for migraines, and my breast cysts still come back each month, and my pms is actually worse, and I have no motivation to do anything. So, I will stop using this today. I have decided to just try my best to live healthily ( I already run and eat pretty healthy.) I will still enjoy my coffee and wine, and just know that there is no magic cure for some of the issues I have. I'd rather just let my body do what it wants hormone-wise than to try to fix it and make things worse--hormones are very powerful!!! Even bioidentical ones. F 37 2.5 months
1/12/2010
 1  low progesterone level in test Within first week of taking 100 mg compounded prog., had horrible symptoms of the worst period ever for 3 weeks. Started gaining weight and very bloated. Thought I was maybe pregnant, took test, turned out neg. So bloated I can't wear my rings. It seems many people have problems with this supplement, but if you have many symptoms that affect your life-style, it's worth trying and keeping in touch with your doctor about what happens. I just went off because I didn't have anything bothering me in the first place. Now I'm fat and bloated and waiting for that to go away. F 44 7 weeks
1/3/2010
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 1  Insomnia capsules,low dose...headaches, nausea, itching on 1 side of neck & upper chest, flat/round red spots on face, absent-mindedness & confussion all leading to episode of dangerously high blood pressure, speech/cognitive impairment, tremors/shakes, felt "far away"...1 week post "stroke-like" episode & still have speech/cognitive/confusion trouble. How long might these problems last? 135lbs, 5'6...-full hyster-ectomy 05/00, no HRT. Take low dose generic Welbutrin + 10-20mg(usually 10mg) of Aderall per day. Also on generic brand Synthroid and Fosomax. F 47 3 weeks
12/18/2009
Email
 4  menopause symptoms Right now I'm experiencing stiffness and cramping in pelvis and legs, just like premenstrual cramping, but my period has not come. Have had these symptoms for 3 days, beginning at onset of use of proges this month. But breast tenderness has gone, am sleeping great, moods are better. Have not gained any weight but am bloated right now with cramping. I'm a clinical exercise physiologist working in women's health. I believe that many symptoms listed on this forum are the result of the initial effects of progesterone up-regulating estrogen receptors. When we are estrogen dominant, are exposed to too many xenoestrogens in the environment/food, or are overweight, our estrogen receptors lose their sensitivity.The first thing that should happen with progesterone is to retune up estrogen receptors making them more sensitive, and so symptoms of excess estrogen get worse in the first couple of months of progesterone use. Also, many recommended doses are too much; even often Dr. Lee's recommendations. Other docs like Mercola [mercola.com] and WomenToWomen use much less. I'm down to 1/16 tsp 1xday. And oral progesterones are really problematic bc you can't control how much gets into the blood [liver breaks down]. Blood tests are not reliable indicators of free progest., so if you're having questions about levels, get a saliva test. And I just learned today about the problem of progest. creams containing parabens and cramping symptoms. Parabens are powerful xenoestrogens and make estrogen symptoms worse. My cream has them [KAL]. Will be changing to today. F 56 2 months
12/16/2009
Email
 3  for perimenapause depression, and excessively oily skin Although the progesterone helped a great deal with the pain I have decided to wean off of it because of the depression issues. It did help me with food cravings (maybe i didn't eat because i was soooo depressed), and lose weight. However, i would rather have pain than be a zombie. My personal opinion with progesterone is that we are all different...some women have tremendous success. I didnt, but i wouldnt throw baby out with the bathwater. I believe some of you are experiencing problems because when you start progesterone it "wakes up" your estrogen receptors. You must try this for several cycles before giving up. F 40 12 months
12/11/2009
 5  missed periods severe hot flashes ; the worst side effect for me after using for a month is very sore breast nipples. the first two weeks I WAS STARVINGbut that is betterand Iwas fatter in the stomach but that is better since m using only one eighth of a teaspoon now. I also have more enery but dont like the soreness in breast nipples. I noticed you take as little as possible and it works without as many side effects. Itdid solve my horrid hotflahes and that crazy feeling with menopause and peri-menopause. Im going to give it a chance but Idont get this soreness in breast. I had problems for years with cramps,heavy bleeding,pms, food cravingschocolate,cyst on ovary,headaches you name it.I had it with my period, and once Ihad a pre-cancerous pap smear. I wish I would of knew about this cream then. This cream is a cheap cream from walmart but it has chemicals in it I DONT LIKE SO i m going to try a paraben free formula next.Its worth a try If you were getting like me and not funtioning wellwith depression and all that other female junk!!!!!! M 52 1 months
12/2/2009

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