PROGESTERONE Reviews (PROGESTERONE)

Average Rating: 2.2 (522 Ratings)

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 ESTROGENS PROGESTINS INFERTILITY

 Type: Rx Drug

  

PROGESTERONE  (PROGESTERONE):  Progesterone is a type of female hormone (progestin). This medication is similar to the progesterone that your body naturally makes and is given to replace the hormone when your body is not making enough of it. In women who are not pregnant and not going through menopause, this medication is used to restore normal menstrual periods that have stopped for several months (amenorrhea). Progesterone is also used as part of combination hormone replacement therapy with estrogens to reduce menopause symptoms (e.g., hot flashes). Progesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. This medication is not for use in children. Progesterone must not be used to test for pregnancy.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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More on PROGESTERONE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROGESTERONECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  menopause calmness, clearer mind, weightgain I experienced an early menopause at 37 i started having abnormal periods which caused alot of excess estrogen. along with feeling awful, terrible weight gain. I was really a wreck. I took progesterone and it was a life saver. It balanced me out. I got off of it at some point and now years later I am in full menopause. Knowing the need and benefits of progesterone and my age 42, with early menopause, I decided to get back on it. I guess now since I do not have as much estrogen, it is horrible. Gives my immune system chaos, sinus and yes. weight gain in one month. My jeans do not fit right. Hips, butt, thighs gaining!! I was very thin and athletic. I cant take it! It is probably the inital extrogen receptors waking up, and I know you have to have estrogen to balance each other. It seems very slim women just do not have as much to balance out. Menopause is terrible!! M 42 7 days
2% 1X day
1/8/2011
 1  menopause I went on bio identical treatment after severe menopausal depression symptoms...I felt wonderful young and vibrant after starting the treatment and continued for a year. But...after picking up my last compound prescription 3 months ago, I noticed something was wrong with me....after applying the cream, I told my long time friend OB/GYN that something was wrong and I suspected the compound pharmacy mixed it wrong? But more than likely I just needed to be re-tested...I immediately became depressed, agitated, and an over all feeling of dread....I voiced my concerns that went unheard until I hit rock bottom shortly after and tried to commit suicide and spent a week in ICU....I am no longer on the HRT, but am on Zoloft which surprisingly has me on an even keel now...I still get night sweats sometimes, but am happy to be alive and no longer deal with the depression that comes with Menopause. Hormones are nothing to play around with, if you use them, my advise is get tested often... F 47 1 years
10MG 2X day
12/27/2010
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 4  PMS Severe aggression. Sleepless nights... I started taking kokoro's progesterone cream a few months back due to dealing with severe PMS for 10 yrs. progressively getting worse after having kids. Being I am only 28 no Dr would test my hormones because i am too young to have any issues.. Anyhow I started the cream and felt great I then got a little wild and noticed I am starting to get symptoms of too much progesterone as some of the others have posted... I just thought I would let you guys now when you get these symptoms your taking in too much ;) I lowered my dose and the symptoms are gone. Good luck ladies! F 28 96 days
1/8 tsp 2X day
12/16/2010
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 1  Estrogen Dominance Nausea, night sweats, irritable, diuresis. Feels a lot like PMS to me. Don't need that at my age. Also, painful hands - weird. I'm a RN and feel this is not a simple medication. I hope to get off this 'natural cream' and get back to my normal. Way too powerful for me and natural doesn't mean safe, at least not for me. I hope to avoid environmental estrogens more and work on other safer adjustments to diet. F 71 6 days
1/16th tsp 1X day
12/14/2010
 4  Hormone Imbalance Initial increase of estrogen dominance symptoms (first 3 months); low level depression; bloating still there but less, dry eyes are better, constipation better, energy level slightly better and focus/thinking has improved a bit I take the smallest of small doses (a sliver of cream) from day 14 through day 24 of my cycle. I've had HI symptoms for the last five years - bloating, fatigue, dry eyes, irritability, constipation, foggy thinking, etc. I used to run a marathon a year, but within a span of 8 months, I couldn't even run a mile without extreme fatigue and dizziness. Drs said that's what happens when you get older (Huh? - I was 35 when this started happening.) I was put on Levoxyl for hypothyroid. That helped, but I still had a lot of symptoms that came and went depending on where I was at in my cycle. I tried a lot of other medications before Progesterone with no improvement just frustration. Progesterone did help some, but I am still symptomatic. Better, but still not myself. I will keep looking for a solution b/c this isn't all in my head, depression or an age issue. This is an endocrine/hormonal issue that is difficult to resolve, but hopefully, not impossible. F 40 4 months
1X day
12/1/2010
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 1   Being hypersensitive anyway, I took less than half the prescribed dosage. My husband and I thought I wqs going to die! Sudden onset of feeling very very hot, racing heart, chest pain, difficulty breathing. It did not go away for about 15 min. I backed waaaay off the dosage, but accidentally put a little too much again the other night. Happened again, only symptoms were more pronounced and took hours to feel better. Even into the next day I feel weak and my pulse is faster than usual. It helped to alleviate my symptoms, but I cant tolerate the side effects. OH! And the Dr. and pharmacist both told me it was in my head. Bull!!! Helps with symptoms, I felt more sane (ha ha), but scared to touch this stuff anymore. I feel it has a highly negative affect on my heart and blood pressure. also, I kept peeing for hours! It made me feel crazy and have terrible anxiety as well. NEVER AGAIN! I thought I was going to die. F 44 6 weeks
30mg 1X day
11/22/2010
 1  To Prevent Miscarriage I had to take this during the second half of my cycle only, so I had to go on and come off of it abruptly month after month. At first side effects were great. Less anxiety better sleep. But when I had to come off, severe insomnia. After 4 months I couldn't take it anymore, so I saw a Reproductive Endocronologist who said my OB put me on a much higher dose that she ever would have. I went down to 200mg. All along I was bloated and would have breast pain, but suddenly I started having chest pains and a severe shocking pain in my left arm. I had to go to the ER, but fortunately I wasn't having a pulmonary embolism or a heart attack. The symptoms continued and got worse. My blood pressure went through the roof! I now have pain, tingling and numbness at random times in all four limbs. Recently I am having trouble with my right side of my head/ear. I have been off the progesterone for a few weeks and the bloat has gone, but the pains etc... continue. After doing my own research it turns out oral Prometrium acts like a benzodiazapine. Very addictive. F 37 5 months
200MG 3X day
11/15/2010
 2  coming off HRT 2 hours after my first dose I suffered a severe sinus headache.I have been using Serenity only a little in the evening. I have discovered that headaches are common side effects.I have certainly had a higher libido but now I am getting stomach ache and I think It could be this cream. It has not improved insomnia and the sweats have been much worse. I am going to throw it away and go back on HRT for awhile. F 59 3 months
15mg 1X day
11/4/2010
 1  brain fog,dry skin,insomnia,libido Felt great for the first week or so: increased libido, skin seemed more radiant/moist. Then I started noticing I couldn't fit into my pants (increase in abdominal girth, butt/thighs). I have always been thin. I work out every day, run/weights. Then I started to get irritable/angry/impatient. Started picking fights with my family members. Oh, I forgot to mention the constipation! It finally hit me, this has to be the progesterone. Now, I find this site and can confirm it! Oh, and I thought I was developing carpal tunnel syndrome, but I think it's just from the swelling in my hands. I actually had to stop yoga because I couldn't do down dog. I'm stopping this now!! I hope these symptoms resolve quickly! Maybe the progesterone cream (bio identical) would be okay at much lower doses?? I'll have to reevaluate this seriously if I decide to try it again down the road. F 46 30 days
25 mg 2X day
10/20/2010
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 2  Perimenopause - Anxiety Rapid weight gain, cellulite, severe constipation, yeast infections, tired F 50 4 months
,25mg 1X day
10/13/2010
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Patient History
 1  TO HELP BALANCE OUT MY ESTROGEN UNCONTROLLABLE EMOTIONAL OUTBURSTS-ANGER,SUICIDAL,DEPRESSION,ETC. JUST WANTED TO CHECK OUT OF THIS LIFE.ACNE BREAKOUTS ALONG CHIN LINE,BIG LUMP BELOW MY CHIN THAT WONT GO AWAY,WEIGHT GAIN, ANXIETY ATTACKS.BREAST SWOLLEN TO WHERE THEY HURT. THIS HAS TRULY BEEN A NIGHTMARE TO ME. I HAVE QUIT TAKING THIS PRODUCT IN HOPES OF GETTING BACK TO WHERE I DO FEEL BETTER. I ACTUALLY HAVE FELT WORSE SINCE TAKING THIS PRODUCT. I THOUGHT THAT THIS WOULD HELP ME SLEEP BETTER, FEEL OVERALL HAPPIER, BUT INSTEAD I STILL WAKE UP AT NIGHT AND FEEL JUST NUMB. I HAVE NEVER IN MY LIFE ACTED LIKE THIS WITH THE UNCONTROLLABLE EMOTIONS ETC. I HAVE NEVER THOUGHT OF SUICIDE UNTIL TAKING THIS PROGESTERONE. I FEEL LIKE I HAVE BEEN A GUINEA PIG -STARTED OUT AT 150 ML A DAY WITHOUT ANY BLOODWORK DONE AND NOW I AM ON 50ML A DAY AND STILL FEEL THE SAME.I TRULY FEEL LIKE THIS IS POISON TO MY BODY. F 47 1 months
150 -50ML 1X day
10/6/2010
 1  ovarian cancer due to endimitriosis I felt extremely moody...cried a lot, hungry and my joints were very achy. I felt like I was a completely different person. Horrible experience. F 39 7 days
30mg 1X day
10/5/2010
 4  menopasuse Started with full program of hrt - bio-identical hormones in cream form-- progesterone; biest; testosterone with armour thyroid;dhea and pregnenolone.. Thyroid went away first - shakes --then dhea--angry all the time, impatient, then prenenolone. Took several months to feel good and get regulated, had to be patient. Gradually felt great. Energy levels up, on task, no hot flashes. Will be making adjustments soon as have started some spotting. You shouldn't be taking progesterone cream on it's own. You have to balance. For many years I did 4 capsules of primrose oil with one capsule of wild yam. It worked great. Fibrous breasts elevated within a week. Stopped and decided to do bio-identical hrt. Looking at iodine supplements for thyroid support. F 61 2 years
50ml 2X day
10/3/2010
 1  Estrogen Dominance Horrible experience with this drug. I was having trouble with my periods (they were 20 days apart), went to get accupuncture and was prescribed bioidentical progesterone. I have always been in good shape (5'4", 120 lbs) but this stuff caused me to gain inches and inches of cellulite. I did not change my diet or anything else. When I stopped taking it the cellulite would not respond to diet or exercise. The only help I got was from an herbalist. She put me on Hydrolyzed Collagen and a Nature's Sunshine product called Cellu-Smooth with Coleus. It has been four months and I am starting to notice a change in the cellulite. I went to many doctors and had almost given up because no one else could help me-didn't even believe me. This stuff is poison! I know that it works for some people but it is not worth the risk. If you are having problems with hormones, see a certified herbalist. Herbs take time to work so you have to stick with it. F 43 3 months
3X day
9/30/2010
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 2  Migraines Racing Heart, Anxiety, Weight Loss??? Wow... this stuff is not what I expected! I was taking 5OMG of bioidentical progesterone made by a compounding pharmacy on days 3-16 of my cycle. Then bumping the dosage up to 100MG for days 16-28. This is what my MD prescribed & I was SO excited to see if I wouldn't get migraines. Well, I didn't... until week 3 on the meds. Not only did I get 4 migraines (4 days in a row) but I started having crazy anxiety & heart palpitations that landed me at the local Urgent Care. My Dr. swears that it couldn't have been the progesterone b/c it's supposed to have a calming effect on women. NOT AT ALL what was (is) happening to me. I'm so glad to see all of your posts here indicating that I am indeed correct, but I'm really disappointed that obviously my Dr. doesn't really know the side effects of these meds. I've been off for 9 days now, the symptoms are definitely fading... but some days are worse than others. I fully expected to be feeling myself again by now (migraines or not) but I am still slightly plagued by a feeling of unease... and my heart races every now and again for unspecified periods of time. I'm just praying that this stuff gets out sooner than later, I'm starting to think maybe I have issues & it wasn't the meds. Have any of you out there have advice or experience with how long it takes for the progesterone symptoms to subside? I greatly appreciate your insight. F 36 30 days
100MG 1X day
9/6/2010
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 2  estrogen dominance, PMS, migraines I started out using compounded bioidentical progesterone cream about 4 mos ago. I am highly sensitive so used a very tiny dose at bedtime only. Was using it from mid cycle to when my period started. Good results at first...slept better, depression around PMS was relieved, more energy two weeks before my period. Did not help with pre-menstrual migraines, breast tenderness, or irritability. Second two months used it from days 5-7 to when period started (was recommended I use it more because I feel rotten the first two weeks of cycle). It at first relieved some of the symptoms but not 100%. Within the past month have noticed more sleepiness and tiredenss that makes no sense. Overall have noticed unusual weight gain especially in stomach and hips. I am entering into peri-menopause and have begun to struggle more with weight gain...but have noticed recently my clothes are getting tighter and tighter. This has happened very quickly and I have changed nothing in my diet. If anything F 40 4 months
1X day
9/2/2010
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 4  Progesterone Cream Fibroids in breasts decreased as well as bloat and pain, decrease in bloating all over body, warmer (I'm always cold, on levothyroxine), less moody, more energy, no more dry eyes or constipation. Less food binging episodes. I tried the cream years before, at the recommended amount. It was good, then disastrous. I went off it, but always remembered how it did help at first. So, I recently decided to go back on the cream, but just use a tiny, tiny amount...like 1/16 pea size or even less. It has been just great. No bad side effects. I read this blog years ago when I did go off it, and thought, maybe for me, I just need a smear (literally) to get the proper effect. I was right...I think women should just start with a tiny amount for a few weeks, then adjust from there. Some will need more, some less. I just need a little (and I mean LITTLE) amount, and I get all the benefits...don't follow the dosage..follow your body. I am 5'4", 100 lbs. The recommended dose is just too much for me. I found my body likes it around 10:00 am...that's when my breasts start to bloat up...I put it on, and within half hour, I am much better...I never take it in the evening...you have to find what is best for you...I even try skipping a day, to see how my body feels. Trial and Error. F 44 2 months
1X day
8/21/2010
 1  insomnia Experienced tingling in hands and fingers. That was followed by swelling which was followed by extreme pain! My right hand became so swollen and painful I couldn't type or hold a pencil. It was like having carpal tunnel. Made the insomnia worse! I took 200 mg/day of bioidentical progesterone with 2.25 biest orally. Prescribed by my obgyn. I was having normal periods, but some perimenopause symptoms. I stopped taking it after the fourth month. I think the dose was so high it caused carpal tunnel like symptoms. Very painful! If you want to try progesterone, I would recommend starting with a very low dose to see how your body responds. I went to my primary care doctor and she said she had never heard of progesterone causing this. She ran some blood work and I had a positive antinuclear antibody test. This test was included in bloodwork a year ago and four years ago. Both test were negative then! I think the positive test has to do with the overdose of progesterone. I have thyroid antibodies and take thyroid med (naturethroid), but have never had a positive ANA before!! Not good. Be careful with progesterone and estrogen even if it's bioidentical like this was! I've been off of progesterone for 3 weeks and still have swollen, painful hands - they are about 50% better, and I'm sure this will go away, but be careful! F 49 4 months
100 mg 2X day
8/21/2010
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 2  peri-menopause F 44
20mg 1X day
8/10/2010
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Patient History
 3  at first pms issues I was told about Progesterone Cream through a friend who heard Dr. Lee on the radio. I looked into it to see if I could get help with PMS. When I first started taking it, I bled a lot more, so lowered dose. Later I developed a fibroid tumor; hemoraged (sp?) after about 1 yr of trying to heal the tumor with the Progesterone Cream. Rushed to emergency. Had emergency hysterectomy to stop the bleeding. I did not take this for awhile after, but, for some reason, tried it again...a few yrs ago. About a yr ago, I developed a goiter on my neck. In the last 4 mos, I started having panic-attacks, GERD (cannot eat without feeling sick). Never even thought of the Cream. I decided today to check if there might be a connection. I had had a saliva test done through zrt labs, and it said I was low on progesterone, even though I had been taking it for awhile. So, I upped the dose, and am even worse with eating, dizziness, panic-attacks, feeling like I cannot breathe, etc. I think I need to F 53 6 years
1/4 t 1X day
8/9/2010

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