PROGESTERONE Reviews (PROGESTERONE)

Average Rating: 2.2 (522 Ratings)

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 ESTROGENS PROGESTINS INFERTILITY

 Type: Rx Drug

  

PROGESTERONE  (PROGESTERONE):  Progesterone is a type of female hormone (progestin). This medication is similar to the progesterone that your body naturally makes and is given to replace the hormone when your body is not making enough of it. In women who are not pregnant and not going through menopause, this medication is used to restore normal menstrual periods that have stopped for several months (amenorrhea). Progesterone is also used as part of combination hormone replacement therapy with estrogens to reduce menopause symptoms (e.g., hot flashes). Progesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. This medication is not for use in children. Progesterone must not be used to test for pregnancy.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROGESTERONE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROGESTERONECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5   Dr. John Lee's progesterAll cream and the experience I had felt very negative the first luteal phase monthly cycle and half of second month I have been on it but somewhere along the way I began to feel calmer -- or less intense. I am still the same energetic person but my mood seems to be less intense and even if I get upset or stressed it seems to be milder. Again, at first everything negative was stirred up: old flare up of genital herpes, itching, BV, food cravings, moodiness, feeling depressed and negative mood... then the second month and second part of cycle when I began the progesterone cream, after a few days.... I was smooth sailing and even lost my appetite for sweets, carbs, wine etc. I am in the process of becoming even more of a super hot babe. I did notice I am not sleeping as heavy as I like to but I am not going to give up... my body is still trying to get used to this Progesteron Cream. I am an avid healthy person, good figure to begin with, 5' 6/7", considered very pretty, 135 lbs. but I began having HEAVY PERIODS and felt myself ageing in general and wanted to try out progesterone cream. I had my salva tests done for 2 consecutive months to compare and while overall healthy the second salvia test showed low progesterone and the ratio was low to estrogen -- so voila! got on it. I think many factors are considered for each of us so keep on experimenting until you find your balance. F 49 2 months
20mg 2X day
5/9/2011
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 1  Cramps, heavy bleeding, emotions. I was using a natural Progesterone to help with extreme cramps, heavy periods and peri-menapause. Starting out..it did help with the cramps and the heavy bleeding. Then I started getting fat and bloated around the middle. I thought my over 40 body was just changing. I ran out of the stuff and did not take it for about a month to 6 weeks. During that time, the bloating stopped and my weight dropped. This was keeping me fat. I know it was this. I'll deal with the cramps and bleeding with motrin the best I can. I thought it was peri-menapause weight gain, but it was Progesterone. I don't recommend it, try something else. F 45 1 years
1X day
5/5/2011
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 2  low progesterone/perimenopause Everything was good until around day 8. I woke up with the worst hot flashes I have ever had. CHest was burning, sweating, heart rate was extremely high. I felt like my insides were on fire. I was convinced I was having a heart attack. This lasted to some degree into the next day. I continued to have hot flashes for around the next 3 days. I reduced my dosage to a very small amt. Called my NP who was surprised I was having this reaction. I am considering stopping this treatment. I have underlying anxiety & this has only made it worse. I started searching the internet for info & ran into this site. I am so thankful I did. I thought I was going crazy!! I know there is supposed to be a leveling out period but I'm not sure I can withstand that. I am at day 14. Hot flashes are leveling out however still have sweating & just a general feeling of not "being right". Also at day 16 I am supposed to increase my doasge til day 25. Very apprehensive to do this at this point I am taking bio identical progestorone cream compounded in a highly respectable pharmcy. I am supplementing with adrenal support capsules which do seem to help my energy level with out any side effects. Just not sure how to proceed at this point. F 41 14 days
0.5 ml 1X day
5/1/2011
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 1  Menopause Gastric distress, mental confusion, felt like fainting several times, weakness, sore muscles. This drug made me feel worse than I have felt in many years. On the 2nd day taking the drug I called the NP who prescribed it and was told I "must be coming down with something, Progestone doesn't cause those symptoms". Then I found this site and confirmed it was causing the symptoms. I could hardly think at work and was in tears trying to get through each day. I've now been off for 2 weeks and am feeling much better, quit feeling like I was going to faint within 10 days of quitting the drug. Now mainly gas and indigestion. I was taking bioidentical Progesterone pills. F 54 12 days
200 mg 1X day
4/28/2011
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 1  Estrogen Dominance/Low Progesterone Made my Hot Flashes ten times worse and ten times more often! Excessive weight gain around middle. Bloated, even though I had no appetite. Constipated, Fatigued. I did the saliva test and it showed that my estrogen was high and progesterone was low. I used a bio-identical cream from a compounding pharmacy. After 4 days of using this cream my hot flashes became much more severe and a lot more frequent! It was extremely difficult to get up in the morning and seemed to take me forever to get going. I should have stopped taking it then but I thought it might get better, but of course it didn't I also gained 5 pounds in 11 days, all in my stomach, even though I work out 5 days a week and eat healthy. I've been off it now for 3 days and the hot flashes are pretty much gone. The weight , now that is a different subject!! I am going to look into a more natural solution. THIS STUFF SUCKS!!! DON'T USE IT!!! F 50 11 days
20mg 1X day
4/13/2011
 1   This is the second time I have tried taking a progesterone product. The first on was a cream, the latest one was an essential oil. Both times I experienced immediate and drastic negative emotional symptoms. Cried all day, wanted to do nothing but sleep. These symptoms are not normal for me. Too scary for me to continue. Plus, both "natural" products have a concerning statement on the label that says they contain an ingredient known to the state of California to cause cancer. Not very reassuring. F 52 1 days
cream 1X day
4/5/2011
 3  Estrogen dominance, sleeping issues Sleeping better, breasts still tender, no weight gain or loss. Have gained about 10 pounds in the last year. Work out 5 times each week and keep calories around 1500 per day. F 53 21 days
40 mg 2X day
4/3/2011
 3  PMS Extremely tired, bordering on sedation, slightly more depressed, nearly confused thinking, need to sleep all the time. I tried bio identical progesterone for three months and have gradually become very tired all the time. The hot flashes are gone though, my mood is definitely better i.e. not flying off the handle all the time with PMS, but I am so tired all the time and bordering on mental confusion, so I don't think its worth it. I have stopped taking this cream for over a week and I still can't shake myself out of it, need to sleep all the time. I did read by Dr. Mercola that too much progesterone stops testosterone working and he also suggested working on the adrenal's so I think thats what I'll do and maybe the PMS will work itself out. I don't think using the cream is worth it for the terrible side effect of sedation, it'll probably take a few weeks for the stuff to get out of my system, oh well, back to the drawing board. Also don't think that it's safe just because its natural, some herbs can be lethal if taken too much of, I think you have to be very careful using bio identical creams. F 50 3 months
1/6 1X day
4/3/2011
 5  hot flashes F 50 3 months
1X day
3/31/2011
 1  menopause Severe Anxiety, headaches, dizziness, neck and back pain, weight gain. After several years on bio-identical HRT, I finally figured out that the estrogen patch and progesterone were actually causing my symptoms, not helping them. I spent thousands of dollars on test, Dr. and hospital visits. Now the only symptom I'm having is hot flashes, minor to deal with compared to the other symptoms. F 53 5 years
100 mg 1X day
3/28/2011
 1  PMS,spotting,fatigue,hair loss,etc. The main side effect I had were HEART PALPATATIONS, ANXIETY, MOODINESS, MORE ACNE, FELT LIKE CRYING, ETC. The heart palpatations sent me to the cardiologist who basically told me they are not too knowledgeable on bioidentical hormones, but that was what was most likely causing my symptoms, since that was the only thing I had done differently recently before it happened. The only thing that the progesterone helped were my cramps. I still had spotting and my acne got worse. I cannot take the heart palpatations or anxiety so I've decided to stop. I feel the same as others have posted, in that it has bad effect on my heart. I think I'll deal with my cramps and live on Pamprin to alleviate my monthly PMS. I was in a better position doing that! When I inquired about the heart palpatations and spotting, etc. with my OB/GYN they acted like they didn't know what I was talking about and told me to see a cardiologist. When I told my cardiologist what the OB/GYN doctor said she basically rolled her eyes and said they should have known this. I think b/c bioidentical is so new, doctors are just trying to make a sale and don't really give a sh*t about their patients. it's a sad world out there! F 35 28 days
100 MG 1X day
3/27/2011
 1  Heavy hot flashes and night sweats Depression, excessive weight gain, crying, sadness, extreme tiredness, lack of motivated and bouts of blurred visions. Very scary to me as never experienced this before. Unable to "snap" out of it or push myself forward. Been taking a combination of 100 MG Progesterone and 2mg estradiol. Initially was able to sleep through the nights yet unable to get up in the am and function. Always felt Drunk, groggy, blurred vision, unable to concentrate. Though it did reduce the hot flashes these symptons did not allow me to function normally. I am a psychotherapist and watched my mood change so drastically I got scared and then dipped into deep deep depression. Took this combo for 6 weeks, stopped 2 days ago after sleeping, groggy for for 3 days. I am self employed, active and never NEVER have experienced this before. I am 5'4, petite, hx of weighing 120-123 and currently at 133 down fro 137 4 days ago. I am still slow today gut the blurred vision is clearing up and the fogginess. Consulting my OBGYN for creams. F 53 6 weeks
100 1X day
3/13/2011
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Patient History
 5  PMS (Estrogen Dominance) None. I take bioidentical hormones (25mg Progesterone and DHEA combo plus extra 25mg of Progesterone 14 days before my period to prevent PMS symptoms) - natural, safe. Don't take synthetic progestins! The bioidentical hormones have SAVED MY LIFE. I experienced Estrogen Dominance since I was 18. It got worse after a lot of stress, when I got Adrenal Fatigue and Western Medicine had no clue what to do, even a Stanford Gyno. They kept trying to give me antidepressants and birth control pills, which just made me a TON worse! It took some tweaking and of course, it takes at least 3 cycles to settle, but now, I have NO depression or carb cravings at all! I get a little irritable still before my period, but that I can live with. *I should also note that the Adrenal Fatigue was treated wonderfully too by the Alternative Med doctor (licensed doctors better than PA's etc. IMHO) on supplements that cured my insomnia and thyroid med's (T3 was low but T4, TSH okay). F 43 1 years
25-50 mg 1X day
3/7/2011
 1  Menstrual Migraines Severe Abdominal Cramps and Nausea, Insomnia, Explosive Bowel Movements, Severe Stomach Bloating After the night I had, my heart goes out to anyone taking this poison. These side-effects happened over ONE night for me. I dare not EVER use it again. I have never experienced anything like it in my life. I truly contemplated suicide to end the pain and sickness I felt and I AM NOT a dramatic person. My husband was in shock because I NEVER complain...not even with my pounding monthly migraines that make me vomit and lose vision is one eye. DON'T TAKE THIS CRAP! Find another way!!! F 32 1 days
50 mg 1X day
3/3/2011
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 4  Estrogen dominance, heavy bleeding I take a bioidentical compounded progesterone. Thus far, no side effects noticed, other than I sleep better through the night which is good! I take 30 mg days 5-11; 60 mg days 12-26. I am curious to see if it will help my heavy bleeding with my period next week. F 47 2 weeks
30 mg dys 1X day
2/28/2011
 4  No ovulation, no balance Sleep better, less water retention, clearer skin, some breakthrough bleeding I have hashimoto's hypothyroidism, and after I stopped a birth control pill, I didnt start ovulating (found from blood hormone tests, where progesterone in lutual phase was basically 0). I was started on 100mg of bio-identical progesterone cream 3 cycles ago. I still am trying to get my cycles under control (as am experiencing breakthrough bleeding), but after 8 months of not ovulating (and not making any prog while estrogen was fine), gaining weight, feeling menopausal at 26 yrs, the progesterone has definitely helped. F 26 3 months
100mg 1X day
2/20/2011
 3   At first my Naturpath prescribed to me 50 mg progesterone cream with an additional 50mg pill for evenings. I literally felt like I was on a morphine drip the next three days after one dose! So, i stopped the evening pill and then maybe one day out of six, i felt relaxed and able to actually get up and work; but the rest of the days i just stayed in bed, couldnt get motivated, and could not move basically. Now remember, I am an A type personality. Real estate broker on the go, go, go! So, i reduced the cream again to only 10 mg cream at night. so now i still feel groggy half the days and was thinking "great, I finally feel relaxed and now the grogginess will go away.. NOT!! I now get REALLY SEVERE NIGHTMARES..EVERY NIGHT..SOMEONE IS MURDERING ME, TORTURING ME, SOMETHING HORRIBLE AND DISGUSTING AND I CAN'T WAKE UP! In addition, my hands are swollen and hurt to type. So, i am getting off it completely! Going to Mothers market to see what i can get even more natural. The nightmares a I also take a combo cream of estadiol and testosterone and i hope that by not taking the progesterone cream will give me any other side effects.. what in the he-- is wrong with all this?? I am motivated now to start doing yoga, going to gym, eating better and just taking control of my own destiny.. there s gotta be a way..someone email me about what i can do please so i dont have the vaginal pain when i am off estrogen without taking progesterone.. even the pharmacist could not believe that taking only 10mg has any effects on me.. i am sick of them telling me "I have never heard of this before!!" BS.. i read it in the other comments.. let's not let them disempower us.. F 47 6 months
10-20 mg 1X day
2/19/2011
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 1  low progesterone Dizzy, stirred up my candida in my gut, massive headache I am very hypersensitive to any type of medication, I did the progesterone cream and overnight it happened I woke up with gas bloating cramping in my intestines because I have candida was not fun called the bio-identical pharmacist and he said I have never heard of that happening with progesterone it is very well tolerated ha! ha! than I tried it again and overnight I developed a headache and dizziness I took something for my headache but it just got worse and worse almost took myself to the er took all day to subside but was still lightheaded. Once again I called the pharmacist and 2 different ones said oh no that doesnt sound like it would be from the progesterone (bull) made me feel like I was going crazy. done think just because it it "natural" doesnt mean it will not give you side effects. I do not know what to do now cant get my money back either F 47 2 days
100 mg 1X day
2/10/2011
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 1  relieve estrogen dominance dizziness, vertigo, nausea, extreme fatigue, insomnia, night sweats, hallucinogenic nightmares, weight gain, water retention, depression, "foggy" thinking Have been taking ProGest bio-identical cream to relieve estrogen dominance symptoms for early phase of menopause. Seemed to work for the first 2 months - was able to sleep, mood swings lessened, hot flashes disappeared, etc. But during the last 5 days of the third month the nausea and dizziness began, along with extreme fatigue, and breathing difficulties similar to extreme congestion. This occurred daily for each of those 5 days. Stopped for the prescribed 7 day "rest" and after 2 days the adverse symptoms went away. Thinking I had picked up a virus, I started my 4th month of progesterone after the 7 day break. After 3 days on the ProGest cream, the adverse symptoms were back in full force - and it was the only drug I was taking. Could hardly function or make it through the day. My guess is this stuff does not shed readily, builds to intolerant levels and starts to upset other adrenal hormone levels. Have stopped using until more science occurs and take menopause for what it is. These side effects remind me of the body's reaction to poison and are big warning signs. F 50 90 days
1/8 tsp. 2X day
2/7/2011
 1  Uterine cycsts,PVCs, avoid hyst Headaches,GERD,breast tenderness,acne on laugh lines and chin, joint pain (neck & shoulders) I requested progesterone after my OBGYN suggested I have a hyterectomy due to ovarian cysts. The OBYGY mentioned that the cysts would resolve once I went through menopause - linking the cysts to hormone levels. I asked that my hormone levels be checked and was given a blood test and told that I was not in menopause yet. I asked if I could have my progesterone and estrogen levels checked, and was told by OBGYN and GP doc that there was not a blood test for that - I was not offered a saliva test and at the time did not know that's how specific hormone levels could be checked. So my OBGYN prescribed 30mg of a compound progesterone - not knowing my exact hormone levels. I have been applying a progeterone cream daily for 6 months - the last 6 weeks I have experienced ocassional severe headaches and almost daily dull headaches. I also have broken out with acne around my laugh lines and chin, and have been having fibromyagia like symptoms of joint pain and fatigue. As a result of the symptoms, I have had a brain scan for the headaches, saw a neurologist for the headaches and was told I have "Chronic Tension" headaches - He prescribed amitriptyline (have not taken it yet). I saw a Dermatologist for the acne and was put on an antibiotic for 3 wks. The medical costs of these tests and MD appointments are huge. I wish I would have done a little more research as my symptoms began - I just didn't link the symptoms with the cream. Thanks for your input ladies! F 50 6 months
30 mg 1X day
1/23/2011

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