PROGESTERONE Reviews (PROGESTERONE)

Average Rating: 2.2 (522 Ratings)

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 ESTROGENS PROGESTINS INFERTILITY

 Type: Rx Drug

  

PROGESTERONE  (PROGESTERONE):  Progesterone is a type of female hormone (progestin). This medication is similar to the progesterone that your body naturally makes and is given to replace the hormone when your body is not making enough of it. In women who are not pregnant and not going through menopause, this medication is used to restore normal menstrual periods that have stopped for several months (amenorrhea). Progesterone is also used as part of combination hormone replacement therapy with estrogens to reduce menopause symptoms (e.g., hot flashes). Progesterone is added to estrogen replacement therapy to reduce the risk of cancer of the uterus. This medication is not for use in children. Progesterone must not be used to test for pregnancy.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PROGESTERONE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PROGESTERONECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  trouble sleeping low sex hormones First off, I had to copy and paste a previous reviewers info because my experience has been so similar. Insomnia, uncontrollable shaking, panic attacks, extreme fatigue, adrenaline rushes, feelings of unreality, extreme anxiety, dehydration, hallucinating, can't stop thinking or doing, can't relax at all, feel high as a kite, tripping(doctor said it can make some people trip! wtf?!)feeling faint leading to the emergency room and hundreds of dollars to see an intergrative doctor.I WAS barely hypothyroid and have spent the last 2 years changing my diet, suppluments, iron, cytomel. This seemed to put me over the edge and I wish I could understand what happened? I took Cortef for a year, weaned off about two months ago, started having insomnia but was able to sleep, I started bioidentical compounded progesterone/ estriol/ saw palmetto( for hair receding) about a month later. I NEVER got the famed best nights sleep ever. It seemed to stimulate me. My skin broke out badly which upset me grea How long does this take to get out of my system? Is there anything I can do to make it get out of mysystem quicker? How did progesterone effect my thyroid? Do I need to reduce or quit my cytomel, Im only taking 12.5 mcg. My $$$ doctor said I coild eventually but Im thinking the progesterone spmade me hyperthyroid? How does progesteone effect adrenals? I WAs able to work out a lot more. I lost 25 lbs in about 2 months and Ive gone down 2 dress sizes. Will I gain the weight back now that Ive stopped it? I pray I can get some sleep on my own soon. I wonder if I shoild go back on Cortef? I tried a stress dose and it made my heart pound terribly. F 44 5 weeks
40 MG 2X day
5/3/2013
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 2  Menopuase symptoms Heart palpitatons even though my blood pressure and pulse stayed normal, hot flashes and night sweats became even worse, sore breasts, horrible nightmares, felt very jittery in the morning yet didn't want to move. At night I rubbed it on my neck which was supposed to help with insomnia. Instead, I could feel my heart beat in my neck right where I applied the cream- very odd. Couldn't make it past using it for just a few days. I used a progesterone cream from the health food store (Source Naturals) in hope that it would treat some of the "35 symptoms of menopause" that I've been experiencing. Sadly, it made those symptoms worse. It gave me gave me the same side effects as when I tried prescription Prometrium progesterone and Divigel for menopause. Women seem to either do really well with progesterone or extremly poorly. I remember taking a high progesterone birth control pill (Lo Ovral) when I was younger and it made me feel depressed. I think my body does not like progesterone in any form. F 50 3 days
1/4 tsp 2X day
4/11/2013
 4  DUB I'm giving this a 4 as I've only been on it for a month. I felt better immediately after starting treatment. No hair loss, no weight gain as if now.. Do have acne, but I had the same thing with progestin. Overall feel better since being on this medication. Pill form. Very light period, and no cramping. F 37 10 days
200mg
4/10/2013
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 1  Heavy Periods MAJOR panick attacks, Heart rate went from 80s to 140 Landed in the ER with a positive D dimer test. DIZZY, Felt like I was going crazy, Chest pains, Hair loss, Fear of dying, ANXIETY. TERRIBLE TERRIBLE drug!!! They need to test people before prescribing a drug that can make you go nutts! KEEO THIS POSION OUT OF YOUR BODY!!!! F 34 30 days
10 1xpd 1X day
3/29/2013
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 1  Post men Hemorrhoids, depression, anxiety, dizziness, nightmares, Dr Katia Meier in Centennial, CO did not recognize my symptoms as related to progesterone. She said no side effects happen with bioidentical. She did not recognize my side effects were from elevated levels of hormones due to other medications and supplements I take, some even prescribed by her. Do not take with drugs, supplements, and foods like grapefruit, which inhibit the CYP3A4 enzyme that clears the drugs metabolized by this enzyme. You will have nasty side effects, and dangerously high levels of hormones. Look up all teas, supplements and medications for CYP3A4 involvement, P450 cytochrome enzyme involvement for potential interactions. F 57 3 months
1X day
3/6/2013
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 2  Estrogen dominance Extreme hair loss to the point of balding, anxiety, heart palpitations,and insomnia I started using this cream to combat estrogen dominance I was experiencing after being on HRT for a year. The cream helped at first but after 3 months the estrogen dominance symptoms got even worse.I upped my dose like suggested by Dr. Lee's to over come the estrogen wake up period and things just got worse. I developed severe insomnia and increased hair loss to the point of noticeable balding. My hair is coming out by the handfuls all day long. When I tried to quit the cream I experienced extreme anxiety and crying spells. I am now slowly weaning myself off it and will never try this again. Still trying to overcome the anxiety and hair loss. I'm happy for those women who have had success using this, I'm just not one of them. F 44 5 months
1/8tsp 2X day
2/12/2013
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 5  total hysterectomy/ Fibrofatigue Had terrible fibro/fatigue after received a flu shot following a hysterectomy in 1995 My ovaries and uterus were ruined by the use of a copper 7 IUD for over 15 years The bioidenticals got me off antidepressants, anti anxiety, morphine. Praise God!!! F 57 8 months
20
2/2/2013
 1  Perimenopause SEVERE heartburn, panic attacks/general anxiety and uneasy, worrisome feelings, feeling faint, headache, knots on my chin after my period, weak and tired all the time, dizziness, oily skin I would NOT recommend ANYBODY use this. I went into this very optimistic and thinking it was really going to help me and I felt great about the 1st 2 weeks I was taking it and after that, I started to gradually feel like CRAP. It helped alot with my moodiness and crankiness during pms, but the other side effects are NOT worth my continuing this medication. I take it in a cream form at night with estrogen cream, that I rub on my forearems. I have had MASSIVE bouts of heartburn, to the point that I feel like im having a heart attack. I have always been bothered with heartburn, but could always control it with prilosec and a restricted diet ( I use NO caffiene, very little chocolate, no carbonated beverages, no booze, dont eat after 7 at night and have done everything that my dr has told me to do to control it), but I have not been able to come close to controling it while on progesterone cream. I also have started to have panic attacks and at times I feel like im going to faint. I also have felt like my airway is being restricted and I cant get a good breath. I got FOUR of the hard knots on my chin that you get before your period, but AFTER my period this time. I bled for 1 1/2 days than stopped for 2 days then bled for 2 more days!!! Talk about aggravated!!! I feel like ive taken a sleeping pill about 30 minutes after I use the cream and I have had really odd/vivid dreams when I take it. Sometimes I wake up and for a few hours I feel almost like a hangover effect...dizzy, weak F 38 3.5 months
50 1X day
1/5/2013
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 4  Perimenopause symptoms Weight gain in the mid-section but nothing else really. The night sweats, fatique, mood swings and cystic acne were almost disabling. My doctor told me it was just normal but I couldn't accept that. Went to an MD who uses holistic approach to treatment. Ran a lot of tests and found the problem was estrogen dominance. Placed on oral progesterone and the results were felt within 2 weeks. I sleep now and don't wake up dripping wet all night! Mood swings are gone, skin cleared up, I have more energy and I actually feel human again. The only bad thing is the weight gain in the belly. I'm athletic and eat right so I'm struggling with that but just being able to sleep again, it's worth it. F 50 30 days
100 MG 1X day
12/19/2012
 1  Low to nonexistent hormones yes all Extreme sleepiness, groggy into the afternoon. Sometimes slept 10 to 12 hours. Started with 100 mg and very vivid, unusual, and hard-to-wake from dreams. Had several very disturbing nightmares. with low dose vivelle dot added, dose of progesterone was upped to 200mg. THE WORST NIGHTMARES AND SEDATION. I MEAN HORRIFIC NIGHTMARES AND SLEEPIN THROUGH 10 or more hours of them. Cannot stop crying and suicidal. This crap is pure poison and I just wish I was dead! I got this in gel cap form from a holistic MD. It's supposed to be bioidentical and cause no side effects. Bull. My MD's practitioner told me only one other person she prescribed to to in "all her many years in practice" has had nightmares. Bull. Practioner took blood to test hormone levels and ave me a Gama drink powder. I just wish I could kill myself right now. I hope I can. F 57 3 months
100 to 200 1X day
12/17/2012
 5  leg and arm tingling and pain I started using OTC progesterone cream at the label dose of 20 mg twice a day. I felt good, but incomplete, relief from my muscle pain. I found that rubbing the cream onto the painful areas really helped a lot! Unfortunately, it seemed like this small dose caused water retention and made me feel really fat. I found a website that talks all about using progesterone cream. They explained that using too little is what causes the water retention and other estrogen dominance symptoms. They recommended using at least 100 mg per day. Since my doc had prescribed 150 mg of oral progesterone (that I had not yet started taking), I figured that dose should be OK. I tried it and my muscles feel NORMAL for the first time in years! When the pain starts to come back, I just put a little more cream on the painful area. I have not gained any more weight with this higher dose and I feel so much better overall. F 44 14 days
100-200 2X day
12/8/2012
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 5  menopausal I was perimenopausal at 38. Also, my hormones were never right after the birth of each child . Symptoms were terrible; doubling-over ovarian pain during ovulation and beyond, hot flashes every 15 mins, no libido and eczema all over my arms & legs. First tried the creams which just didn't work for me. Too up and down with symptoms. Also, it was difficult to keep to a regular schedule with the applications. Finally I came across a place that did bio-identical hormones that are inserted into you every 4-6 months. It is essential to have a blood test before insertion to check your female hormone panel: Estradiol, Testosterone and FSH. Doesn't help too much to check your progesterone through blood testing as it varies so much during the month. Found out my levels were alarmingly low. The estrodial & testosterone are the pellets that are inserted in your backside, with a local first (no kidding!) and the progesterone is taken orally. They don't have a pellet for that, yet. The beauty of the pellets is that they dissolve over 4-6 months and if you are more active a certain time of day (greater blood flow), more of the pellets dissolve into your system. I am very athletic with a high metabolism, hence I have to get the pellets every 5 months. The first few years, it was every 4 months. My life has totally changed for the better. If you do this, make sure to keep copies of your blood test and chart your progress. Take charge of your health and help let the Dr. know what you need. As for periods, you don't have any if you take the progesterone continuously. Btw, I was doing that long before it became popular in Western medicine. I only stop the progesterone if I find my uterine lining starts to build up. Probably about every 6 months. Then restart when my period is completely done. F 50 6 years
200mg 1X day
11/7/2012
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 2  PMS, mood swings, migraines depression, lethargy, heavy bleeding in combination with testosterone I used a blend of bioidentical progesterone and testosterone for two months. At first I felt great on these hormones...energy improved, helped relieve depression and migraines, and I felt I had my life back! The problems began when my second period started while on the hormones. My period was normal but I had unusual depression starting on day 2-3 of my cycle. I felt weird all over! The depression finally eased somewhat and my period ended normally...however, started a second period the day after the first one ended...VERY heavy and I don't ever have heavy periods. At this point in perimenopause I have not had any bleeding like this. I continued to bleed heavy for 3 days as I got off the hormone blend (I felt it was causing the heavy bleeding so decided to discontinue). The whole episode was very terrifying! I was weak and had flu like symtoms. I decided to continue with just progesterone by itself to counteract any estrogen dominance. Experiencing unusual depression, lethargy, dizziness, and sleepiness. I will lower the dose to see what happens. If it continues will discontinue altogether. I would caution those wanting to use bioidentical hormones to proceed carefully. I used them as a last resort and although it was good at first it came back to bite me. Progesterone in excess can cause depression/lethargy because it down regulates available serotonin in the brain. If you use hormone therapy be prepared to constantly tweak the dose and keep a journal! F 42 2 months
1X day
11/4/2012
 1  tested low DON"T TAKE THIS! YOU WILL BE SORRY! IF AFTER STOPPING THIS MONSTER OF A DRUG, YOU EXPERIENCE SIDE EFFECTS FOR LONGER THAN 18 MONTHS, TRY EMOTIONAL FREEDOM TECHNIQUE. LOOK IT UP ONLINE. IT SAVED ME. F 43 10 weeks
75 1X day
11/2/2012
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 1  tranfered from other boyfriend had higher sex drive at first, then became uninterested in sex due to emotional distress, I have many dizziness, and loss, of apatite and increased blood presser being the fact that myself and my boyfriend had so many negative affects from transfer from a user of this cream ( while have sex repeatedly) leads me to think that is some thing all health men and women who do not need it should avoid contact with. So we are asking our girlfriend to stop using it. F 30 5 days
? 1X day
10/17/2012
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 2  Post Menopausal Osteoporosis I was experiencing bad back pain from osteoporosis, and trouble sleeping. My doctor put me on bioidentical estrogen, progesterone, and testosterone creams. Within a week, I began experiencing major bloating, fat deposits began, and have not stopped. Despite a clean diet, exercise, etc. I have gained 25 pounds since starting the creams. I have severe estrogen dominance, despite using products that certify no xeno-estrogens. I have been taking DIM for over a year, but still have the symptoms of estrogen dominance. I would love to get off of this cream, if I could find a solution for my bones. So far, nothing has helped, as my bone density is not getting much better from these creams. F 64 1 years
1/4 tsp 1x
10/6/2012
Email
 1  Peri-menopause/Fibroids EXTREME DIZZINESS, DEPRESSION, INSOMNIA, ANGER, MOODINESS!! I AM POSTING TODAY IN HOPES THAT I CAN HELP SOMEONE WHO IS SUFFERING FROM DIZZINESS DUE TO PROGESTERONE CREAM!!!!!!!!!! I WAS TOLD THAT PROGESTERONE CREAM COULDN'T MAKE ME DIZZY, BUT THEY ARE WRONG AND HERES WHY.... AFTER STOPPING THE CREAM MY DIZZINESS WENT ON FOR 9 WEEKS... FOUND OUT THAT ITS BECAUSE THE CREAM THAT I USED WAS CHEAPLY MADE WITH AN OIL COSMETIC BASE,, RATHER THAN THE MORE EXPENSIVE LIPOSOMAL COMPOUNDS!!! SO BECAUSE OF THIS THE CREAM GOT STUCK IN MY FAT TISSUE CAUSING FLUID RETENTION IN THE BODY, AS WELL AS FLUID RETENTION IN THE INNER EAR, CAUSING VERTIGO AND DIZZINESS...EVEN AFTER THE CREAM WAS STOPPED IT WAS STILL BEING RELEASED INTO THE BLOOD STREAM.. SO HERES WHAT YOU NEED TO DO; YOU NEED TO FLUSH YOUR SYSTEM WITH LOTS OF WATER, ABOUT 2 LITERS A DAY AS WELL AS NOT USING ANY BODY LOTION OR BODY OIL BECAUSE ANY PRODUCTS WILL FURTHER TRAP IN THE PROGESTERONE CREAM. ALSO YOU NEED TO TAKE HOT SHOWERS, SO THAT YOU CAN SWEAT AND DRAW OUT THE CREAM WITH THE HEAT AND HUMIDITY..., THEN VIGOROUSLY MASSAGE YOUR SKIN TO WAKE UP TOXINS WHICH ALLOWS THEM TO BE EXCRETED!! THIS WILL MAKE YOU DIZZIER AT FIRST BUT ONLY FOR A SHORT TIME. ITS YOUR ONLY HOPE OF GETTING THE STUFF OUT! ALSO TAKE A GOOD MULTI VITAMIN AND LOTS OF C. OH OH AND YOU MUST HAVE A VERY LOW SALT DIET WHILE THIS IS GOING ON TO AVOID ANYMORE FLIUD RETENTION ISSUES IN THE HEAD AND BODY!! GOOD LUCK AND PLEASE DO NOT BE SCARED ANYMORE, THERE IS A SOLUTION!!! I AM DOING IT WITH SUCCESS AS WE SPEAK!!! F 42 10 days
200-400mg 3X day
10/6/2012
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 1  TOOK PRO-GEST AS PERI-MEOPAUSAL SEVERE VOMITING, CHEST PAINS, LEG CRAMPS AND LEG PAINS, SEVERE STOUMACH PAINS, NUMBNESS DOWN RIGHT ARM I rubbed a small pea sized amount twice into me over a two day period and suffered severe vomiting, shaking, chest pains, numbness in my hands and arm, leg cramps and leg aches, it took over two days to get over such a small amount that I rubbed in, I was taking this Pro-gest as I have peri-menopausal and was willing to try anything, I advise not to take this as I nearly ended up in hospital F 44 2 days
1 1X day
9/26/2012
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 5  Menstrual migraines If i take more than one, i get sleepy. A small price to pay. This medicine has literally given me my life back after over 30 years of debilitating migraines thay made me close to considering suicide. Do be sure that you get the compounded kind from a wellness pharmacy, NOT the Prometrium or generic equivalant as they are not the same. I take 100 mg morning and evening every day, except for when i feel a migraine coming on, then i take one every two hours or so till the headache is gone. I cannot comment on how it works for other sysmptoms, but for mine i can honestly say it changed my life! F 50 6 years
100mg
9/5/2012
 1  to balance estrogen Insomnia, uncontrollable shaking, panic attacks, extreme fatigue, adrenaline rushes, feelings of unreality, nausea, dehydration, walking sideways, feeling faint leading to the emergency room and hundreds of dollars worth of tests and still doctors told me to switch to sublingual tablets which made me think I was dieing! .Why is anyone allowed to manufacture a product that doctors clearly don't understand the extreme danger of this drug. The doctors don't have a clue about how long this poison can stay in your system and disrupt all of your adrenals. I don't think I will or ever want to use any progesterone again. I have never experience anything like this. Don't put this on your skin because nobody knows how long it will be in your system! F 58 1 years
50 - 80 1X day
8/24/2012

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