WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Major depressive disorder None I can complain about...I talk a lot more, but that's no biggie since I was almost silent before. Muscle twitches and insomnia. Saved my life. I can't say enough good things about Wellbutrin (but ONLY XL...the multi-dose version made me feel like I was on crack). I feel like my life is finally opening up and I can do things. Have begun to make good decisions again. Was kidnapped and sexually assaulted three years ago and have been practically dead ever since. Now I feel I can begin again. I feel brand new, and I began to notice remarkable effects after only 3 or 4 days on Wellbutrin. I take 150 mg 1 or 2 times/day. F 26 5 months
11/4/2005
 5  Major Depression Migraines, Loss of Appetite I absolutely LOVE this medication. I have been taking it for 19 days at 150 mg a day. Before I took it I cried every day for hours. I hated life and I constantly thought about suicide. After being on it for 5 days I felt a lot better but I noticed that an hour after taking it I would get a really bad migraine, so I would have to take 50 mg of Imatrex as well. The only problem with this is by law I only get 9 pills a month. Thanfully, the migraines have started to go away and have become less intense. Also since being on the medication I have eaten a lot less and haven't been too hungry. Before the medication I was eating CONSTANTLY. I haven't lost any weight yet but we shall see. Anyway, I would definitely advise anyone to take this medication. It has helped me a great deal. F 19 19 days
10/28/2005
 4  Premenstral Dysphoric Disorder PMDD Severe headaches & some nausea first 2 wks. Now subsided. Extreme dry mouth,heightened sense of smell, VERY noticable decrease in desire for cigarettes, alcohol--cut tolerance literally in half (which is good due to personal goals to decrease alcohol intake and eliminate cigarettes), seem scatter-brained, ups & downs in energy level--kind of confusing. I hope energy level will increase & stay that way. Waiting for weight loss and increase in libido side effects! Taking 150 mg. in the a.m. for PMDD--very severe form of PMS, but with extreme lows & somtimes suicidal ideations--symptoms disappear after menstruation begins. Currently day 23 on WB & in the thick of PMS time in my cycle, but minus the horrible depressing feelings, rage, & dark clouds/black pit--not ONE suicidal thought yet or feelings of hopelessness. Feel a warm, fuzzy sense of well being and calmness most of the time. In control. Sleep very well. WB like caffeine in the a.m. Did experience some emotional episodes a few days ago, but think was normal due to circumstances. Will gladly trade current side effects for overwhelming positives. Interested to see if there'll be more effects, positive or negative with continued use. F 33 23 days
10/28/2005
 4  clinical depression seizure, muscle spasm, painful constipation (went away after first few weeks), insomnia (for first 6-8 weeks), increased sweating (not too severe), loss of appetie & 18 lbs weight loss i was put on 300mg XL dose after a bad experience with paxil. i struggled with insomnia for about 2-3 months & and became slightly addicted to sleeping pills. about a week or so after stopping the sleeping pills i was able to find non-medication sleep aids & have been able to rest since then. i recently was taken off buproprion after experiencing a seizure. cases of seizure have only been reported in 1-4/1000 users, but i highly suspect this rate is under reported. i strongly suggest limiting alcohol and caffiene intake, as i believe this may have also lowered my seizure threshold. the one thing i did love about the drug was that it worked wonderful for getting me motivated, and there was zero loss of libido (a very common side effect in other anti-depressants). my mood was much more elivated and i was able to focus. i also lost a very noticable 18 lbs in 4 months (the average in clinical trials was a little over 5lbs, again i suspect some under reporting). i r F 26 7 months
10/24/2005
 3  Anxiety/Depression Increase anxiety, increased crying episodes, difficulty controlling anger, constant state of "fight or flight", shortness of breath with increased heartrate. Abdominal pain, nausea. I had taken Paxil two years ago, but experienced withdrawl Panic attacks after I stopped. I only had about 1-2 orgasms the entire time I was on these, (for a year). I generally had no emotional responses to things under treatment with Paxil, so I stopped taking them. I was fine for a few years, the depression started again with anxiety attacks I could not forsee coming. Wellbutrin xl has been thusfar trouble, but reading about how the side effects MAY go away, I am willing to give it a try. What else can I do? I take a very low dose of xanax with this drug in the morning and it seems to mellow me out a bit. I have had sex more in the last week though than in the previous month. That's a good sign, and I have a decreased appetite, also good. It has been hard to overcome the side effects, but I am determined to give this drug a chance. F 35 8 days
10/22/2005
 3  depression/anxiety Dry mouth; dizzy, spaced out feeling; increased anxiety; total loss of hunger; light headaches; uneasy sleep; some difficulty concentrating at times; sweating; flushing of the skin Thank God I'm not the only one having side effects. This forum is a relief! I started with the sample pack of 7 pills at 150mg, and now I've been on 300mg for 10 days. Whew, this stuff is kicking my butt! My doctor prescribed it to take in addition to my Prozac (20mg) and within the first two days I was already having significant side effects. The last few days I've noticed they're pretty bad when I first wake up (WB doesn't let me sleep well, or sleep in). As I'm writing this, I've been up for about an hour and I'm feeling better by the minute, but I ALWAYS feel the nervousness, anxiety, dry mouth, and a strange feeling like there is pressure exerted all around my head. Almost like a mild head rush or fever that never goes away. Well, I take stock in what others have written here, and I hope that within a week or two the side effects will begin to subside. Sometimes I have to fight the anxiety back with Xanax, which I'm avoiding because I know it's very habit forming. I'll p M 37 17 days
10/22/2005
 3  Depression Weight loss about 25 pounds in 9 months, I only needed to lose 10. Increased anxiety, increased agitation, insomnia. Libido unaffected however unable to acheive orgasm which is a strain on my relationship. I am in the process of weaning off for this reason. Too bad it helped with the depression but it killed my ability to achieve the big O. Guess I am one of the small percentage that will still have sexual side effects. Prozac was 10 times worse. I didn't want sex and I gained weight. So I am going to be brave and try alternative methods. I just learned of the sexual side affects because I am in a relatively new relationship. I am not sure the claim to low sexual side effects is that accurate. They make it sound like no one will have them, not true. I would love to know the numbers and statistics of the percentage who do have sexual side effects that are negative. F 39 9 months
10/20/2005
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 2  anxiety/depression Today is my 5th day on 150 mg of XL, doctor did not tell me about any possible side effects. I have severe pain and muscle tension across my upper back, tops of my shoulder and into my neck all the way up to my skull. I am not clenchng my teeth but they are sensitive and sore. The dry mouth is not too bad so far; this is a very big concern for me as I can't take most meds because of severe dry mouth. I cannot sleep. I have had about 9 hours sleep in 3 days. I am crying a bit. My anxiety feels increased. I don't really feel depressed, just uncomfortable about these side effects and wondering if I can/should stick with it. Tonight I took Ambien 10 mg around 9 pm and was very hopeful to sleep until morning but I woke at 2 am and am now writing this at 4 am. My appetite is reduced, no sugar cravings but I really haven't lost any weight yet (maybe 1 pound). I have more energy but am exhausted from no sleep. The sexual side effects with this drug are definitely good ones. I rated this a 2 although I am not really sure yet how to rate it. I am pleased about the lack of bad sexual side effects and the lack of food cravings. It sure hasn't made a dent yet in my anxiety, which I consider to be way more of a problem for me than the depression. I will try to stick it out at least until my next doctor appointment at the end of the month. F 58 5 days
10/15/2005
 3  Major Depressive Disorder Crying episodes, increased anger and irritability I think my depression is a little better. However I don't like the crying episodes and anger. F 17 3 weeks
10/14/2005
 1  depression Sweating, constipation, headache, decreased appetite, but worst of all an increase in MS symptoms like walking difficulties and fatigue. My guess about the walking problems is that the wellbutrin heated me up just a trace and that's all it takes for MS to get bad. I'm on day five of withdrawal and still feel off. F 43 4 days
10/14/2005
 4  Depression and ADHD dry mouth, insomnia, increased anxiety, bloating, trembling I am on 300mgs a day. Most side-effects subsided, all lessened, exept for the anxiety and insomnia. F 20 4 days
10/12/2005
 4  Depression and ADHD dry mouth, insomnia, increased anxiety, bloating, trembling I am on 300mgs a day. Most side-effects subsided, all lessened, exept for the anxiety and insomnia. F 20 4 days
10/12/2005
 3  Smoking Weight loss, occasional groggy periods with energy ups and downs, day dreaming, decreased alchohol use, introverted behaviour (or just being selfish with my time?). Totally quit smoking for 8 days but started at home again (but not at work). Also reduced desires for alchohol (surpressed better than smoking desires). Jumping from 150mg (ZL) to 300mg daily was a bit tough at first - felt 'swimmy' and had to concentrate to focus. Fell more productive at work (with a better attitude). If I refill the Rx it will be at 150mg however, 300mg seems to be a bit much for me. M 38 3 weeks
10/12/2005
 1  diet Increasing out of control unexplained anger, sleeplessness. waking up 3 times a night and then unable to go back to sleep right away,hungry all the time,flushed skin, unexplained pain in my upper back and neck,brittle nails,dry skin,started having depression which I never had before, constipation, urgency to urinate all the time, constant gas, etc. I didnt' have these conditions prior to taking Wellbutrin XL and they stopped a couple of days after I abruptly stopped taking it. The first day that I stopped taking it, I was severely sick with stomach cramps and diareah all day and severe neck and upper back pain. On the second day, everything stopped and got back to normal. I would never recommend this medicine to anyone for losing weight. My doctor put me on it and I stopped it. F 55 40 days
10/12/2005
 5  Major Depression Dry mouth, Insomnia, Increased Libido, Constipation, Gas/Bloating, Unbounded Energy!! Wow, what a godsend! It kicked in after 7 daze and eureka! I could see straight again. I can focus on longer, more intense tasks, I can face the day with hope and confidence... but I'm a bit speedy; no sleep; no downtime; except when I crash for an hour or so during the day; then I'm up and awake, zipping around town... I imagine the rush/insomnia will catch up with me soon and work one over the immune system... but for now the energy is making me feel 10 years younger... I'll sleep when I'm dead! F 29 14 days
10/7/2005
 2  Depression Decrease in appetite, insomnia. I have been on Lexapro(30 mg) Wellbutrin XL(300 mg) for about 5 or so months. I haven't noticed any significant sign of decreased depression even with the two anti-depressants working at almost their top dosage. I have recently started taking Lunesta to help me get to sleep,but I am very dissapointed with these results. I have also taken Prozac and that didn't work at all either. F 18 5 months
10/5/2005
 5  major depression constipation, crying episodes (for very minor reasons), increased libido (good thing!) ability to orgasm (couldn't before), overall...most subsided...except the increased libido :) i've been on it for about a month and the constipation is getting worse. we'll see. i've taken effexor xr (that drug should be banned from the market due to the withdrawal symptoms), and currently on a small dose of zoloft for anxiety (and i feel like it does nothing for me). on wellbutrin XL, within less than two wks the drug lifted what felt like a fog i was living in for WAY too long. i felt like the world was so much more pleasant, and i was able to "feel" again...i'm extremely in touch with my emotions now. it's a little scary, and once and a while i'm worried i'm TOO emotion on this med. all in all i love it. F 27 1 months
10/3/2005
 4  Anger, Chronic Depression Ringing in my ears, but that only lasted a couple of days, tired, complete loss of appetite immediately, I have to make myself eat so I don't get sick. Depression was really bad the 1st weak, vry emotional and alot of crying- seem better now. So far from what I have read, it seeems that I only got a couple of minor side effects, but everyone is different. So far, so good F 25 9 days
9/27/2005
 5  ADD & Depression I am taking this in conjunction with Zoloft and Ritalin. I am hoping to get off of the Zoloft slowly. The Wellbutrin has helped a great deal and the Ritalin has helped even more. I am currently on 200mg of Zoloft and have been for 15 years, 10 mg of Ritalin and 50 mg of Wellbutrin. We'll see what happens. M 36 4 months
9/26/2005
 3  depression Dizziness, loss of appetite, sick to stomach, hard at seeing things. I first tried Lexapro and that had no effect on me, so I was put on Wellbutrin XL. The first 2 or 3 days I was fine. I had a really bad anxiety attack on says 4-5. I'm up to 300mg now and I'm feeling sick and not much of an appetite. But I'm hopeful. F 20 8 days
9/22/2005
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