WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Depression, anxiety Sleeplessness, first 2 days had worse anxiety and panic attacks but subsided, decreased appetite, dry mouth This drug makes me feel alive again. I was so numb for so long. My Dr. told me in the first 2 weeks my anxiety may get worse before it evens out so he gave me a prescription for Xanax if I need it in the meantime. The first 2 days I had a lot more anxiety and anger but now that's better. F 30 4 days
12/15/2005
 4  Major Depressive Disorder Acne,Insomnia,Constipation I really like this drug but it caused me to have acne! I have never had skin problems in my life. My doctor told me to stop taking it for a week to see if I notice a difference. I did, and my skin did begin to clear a little. He took me off of it switched me to lexapro but my depression came back. I asked him if he could put me back on the Wellbutrin because it seems like this is the ONLY antidepressant that has worked for me. Now, I'm back on it...and here comes the acne again. Not sure of how I feel about it. Acne or Depression?? F 30 3 months
12/15/2005
 4  sex drive loss from lexapro First 3 days, nausea and slight headache, increase in anxiety I am taking lexapro in conjunction with wellbutrin. In 4 days, I lost 2 pounds. It really cut my appetite, before with just lexapro I kept thinking about food but wellbutrin helped me with that and I have increased confidence about my weight. I did notice increase in anxiety which is bad because i tend to be anxious and angry more than depressed. However, I have alot of energy and am able to go running for alot longer and I feel better about myself because of my energy. I've only been on it for 5 days so far though. F 33 5 days
12/13/2005
 2  bp1 aa a F 21 5 days
12/13/2005
 5  Depression Slight increase in sweating. Vivid dreams. Increased energy. Takes longer to get to sleep. Increased libido. Two days after being on 150 MG/day, the depression I've experienced for at least 40 years, and did not know I had is gone. The anxiety, pain and the fog appear to be over, hopefully for good. M 52 5 days
12/12/2005
 4  depression, anxiety Temper went out of control after two years and increasing dose to 300 mg I took it successfully for two years at 150 mg dose, but it never really made me feel better, just kept me even. After some additional stress (birth of a child), Dr. increased my dose to 300 mg, anger went out of control, it was my only response to any kind of situation. Reduced dose back to 150 but unable to control temper, irritable all the time. Finally quit cold turkey, headache for two weeks but got thru it. Now back trying to find something like it that works due to return of anxiety and depression. M 39 30 months
12/11/2005
 4  Depression-Lack Of Motivation.... The only noticable side effects taking Wellbutrin XL was an inability to sleep as long as I did before. It does give me a bit more energy, so I suppose that's the reason it's harder to sleep. But that's a lot better than wanting to sleep too long! Wellbutrin XL....lets me concentrate better. It enables me to see things clearer. It gives me a calm sense of well being. I am so much more in tune with my emotions. I really think it's a wonderful medication, if it works for you. I'm also on Effexor 37.5. Maybe it's the combination of these two medications that makes it work so well. I was taking Cymbalta. Oh my, that was the worst medication I've ever dealt with. The side effects made me think way to much about suicide. Not a good drug for me. But with Wellbutrin XL and Effexor 37.5, I'm feeling pretty good :) And yes, some of the side effects that many have posted, DO GO AWAY.... F 55 8 months
12/10/2005
 2  Anxiety Large hives, dizzyness, facial spasms, disconnected feeling I felt great the first week. When the dosage was increased from 150mg to 300mg, everything went downhill. I had a serious allergic reaction, breaking out in large hives. They started around my hips, and then appeared on my knees, elbows and feet. Both wrists swelled up tight. This all happened within a few hours. The doctor did not think it was the drug, and put me on Benadryl for 5 days. After that, I started having jaw spasms that affected my speech. The frequency of the spasms increased throughout the following week. The dizziness also increased. My temples often felt tight. When the jaw/tongue spasms started to occur every 20 minutes or so, I decided it was time to quit. All symptoms disappeared with 48 hours of stopping the drug. F 26 3 weeks
12/10/2005
 1  Depression Started on 150 mg: Headache off and on for the first week, a bit more irritable the first two weeks, jitteriness and shaking the first three-four weeks, tendency towards mania, increased anxiety, lowered ability to control panic attacks, eye twitch off and on for a week at the sixth week, mild dizziness. Constant mild dry mouth, loss of interest in many foods, certain food items no longer taste good, this worsened at 300mg. At 300mg: Very bad headaches off and on for three weeks (was worsened by caffeine withdrawal), increased tendency towards mania, rapid changes between debilitating depression and hyper activity, unusually good mood w/o cause, extreme jitteriness for two weeks, constant trembling, eye twitches several times a day every day, insomnia worsened, extreme continuous dizziness to the point I would fall over, worsening anxiety and panic attacks, restlessness, hallucinations once, sudden deep depression, suicidal ideation, leading to plans to commit suicide. This will be the last anti-depressant I ever take, I said that after Effexor and I see nothing has changed with my response to them. The last time I became rapidly suicidal without any particular cause I was on Effexor and I attempted twice while on it. My manic tendencies were blamed on my self-starvation and addiction to caffeine pills in the past, but continued after I was treated for both. My panic attacks had been under control for many years until Wellbutrin, I have hallucinated in the past but it has been a very long time and I attribute this directly to the Wellbutrin. Despite the horrible memories of Effexor withdrawal I have discontinued Wellbutrin cold turkey. So far my side effects of doing this seem to be, extreme exhaustion, irritability, moodiness, complete disinterest in anything sexual to the point I don’t even think about it, I felt very strange and spacey the first day but that seems to have gone away, some lingering dizziness, headache off and on, but yesterda F 25 4.5 months
12/7/2005
 5  Depression, BiPolar 2 Bad taste in mouth at first. Frequent peeing, tinnitus, dysphoric mania at 450mg I am taking 300mg with 200mg Lamictal for BiPolar 2. I felt pretty good for a while, but increased Wellbutrin to 450 to improve concentration. Side effects were awful so went back down to 300 after a week or so and got very depressed. Mania is totally under control but concentration and depression still occur. When first diagnosed with depression as a teenager, wellbutrin saved my life from 17-20, and any time I stopped taking it and started again it saved me when I started it again (if you start taking it, dont stop because you think you're cured! It's so good, you'll think you don't have to take it anymore.) F 22 6 years
12/4/2005
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 4  Depression, chronic fatigue Frequent urination, dry mouth, night sweats, shaking hands. Was on Prozac and Zoloft for years, not much help. Better with the Wellbutrin XL 300. Hoping the frequent urination will go away. Still not feeling euphoric about starting each day but better than before. F 45 1 months
12/1/2005
 5  To stop smoking Insomia, extreme energy, dry mouth and bad taste, weight loss, some neck and back pain, eye strain, headaches. Although I have these unpleasant side affects, I concider them minor. I have stopped smoking and can breath alot better. I used to smoke a pack day and I was always coughing. It also has helped me to lose weight, instead of gaining which is one side affect when you stop smoking. I love it and will continue to use it. F 36 3 months
11/30/2005
 5  Mood swings - lows were very low Side effects for me so far are: tightness in chest, heartburn, extreme shortness of breath, and headache. The worst side effect is that is makes me extremely light headed. I feel like I'm going to faint. I've only been on Wellbutrin XL for three weeks now and I'm on the lowest dosage of 150 mg., I'm not sure what to do. I like that I'm not having mood swings and far less side effects than that of Effixor. My husband likes the fact that I have an increased sex drive. I'm excited about the possiblility of losing the 30 pounds that I gained with Effixor. So I'm going to try to cut my little tiny 150 mg tablets into quarters and take once a day bringing my daily dosage down to 37.5 mg. (By the way, my vet taught me a trick on how to cut pills. Take the orange high end dog nail clippers (767 Stainless Millers Forge Italy) and they cut the pills beautifully and accurately. Be sure to use a new sterilized clippers that you only use for pill splitting. So we'll see if the side effects go away. F 47 21 days
11/30/2005
 4  depression and smoking insomnia, ringing in the ears, vivid dreams every night which are kind of interesting. Been on 150 mg for 7 days and my mood seems a little brighter. Have been depressed ever since I can remember and medicated myself with drugs and alcohol since I was 13. Quit drinking a few weeks ago in prep. of taking the meds. Still smoke but it doesn't taste quite as good. Do have a bit more energy, especially at night. Still feel different from everyone else...people seem so much more enthusiastic about life than I do...that bugs me about myself!!! Do be careful when driving and starting new meds. I backed into my sons car about 3 hours after taking my 1st dose and have no clue how it happened. I guess I was just being careless which is very unlike me. F 43 7 days
11/28/2005
 3  Depression Difficulty sleeping, anxiety, flighty, spaced out feeling, irritability, sweaty palms, forgetfulness I am not sure if this medicine is going to work for me or not. I am trying to ride out the side effects and see. F 22 10 days
11/27/2005
 3  depression muscle twitching, awakening during night, foggy thinking, mood swings with more anger, depression somewhat improved at times M 48 8 months
11/15/2005
 4  depression , anxiety Day 7 and have had only one episode of severe anger, brought on after 2 rum and cokes, had no memory of things that were said. Will decease with the drinking. Appetite has leveled off, I don;t seem to have constant urges to stuff my face. Day 7 and the urges to smoke are decresed. Not completely gone. I hope this will help me to control my constant worry and building mountains out of mole hills. F 48 7 days
11/14/2005
 3  Anxiety I have not been going to bed every night until about 2 AM then waking up at 7 or 8 AM, I do not feel like getting out of bed in the morning and would rather stay home instead of going to classes. I was on SR for about 2 weeks and I noticed nothing, probably because I always forgot to take it at night. I just started taking XL 450 mgs, I think that is pretty high, havent seen any other comments here about anyone taking that much. I am taking a 100 mg and 350 mg pill every morning. I have noticed that I can sleep at all, I am wide awake now at 4 AM typing this becuase I had nothing else better to do. I hope this changes becuase I cant do this forever! I went to my doctor first to be diagnosed with ADD, but my psychologist thinks that I have GAD. Not sure what this medicine is going to do for me, but we will see..If anyone has any comments about ADD / Anxiety please email me I would love to have another persons opinion on this! Thanks and good luck to you M 18 2 weeks
11/13/2005
Email
 2  Mild anxiety/depression DAY: boundless energy, motivation, focus, enthusiasum NIGHT: increased anger, increased depression, 2 hours less sleep I'm going back and forth on this medication. During the day usually I have boundless energy. I'm more focused and motivated at work. I'm positive, enthusiastic, and work harder than ever. But yesterday on the way home from work (5:30p) I turned into a different person. I was moody, angry (at what I have no idea). I got home and everything my husband said made me mad. I feel so bad for him and that adds to my depression. This is day 5 and I don't feel WXL has made a dent in my depresion. I feel it has made it worse. I'm on 150mg right now. Maybe I need to give it more time? Has anyone else seen positive effects kick in later? I cried all night last night and woke up crying again. I've tried Paxil and Effexor for 2 weeks each and hated both of them. Responses are very welcome. JAZZ PS My libido has lessened and my weight is the same. F 23 5 days
11/12/2005
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 4  Depression/One panic Attack 150 mg on 9th day and the only remaining symptom seems to be the shortness of breath, neck pain, irritability. The pain in the back has gone away, insomnia cured with homeopathic sleep aid, low grade headaches on occasion, no complaints sexually. Feeling like my old self and not so depressed. Hoping the shortness of breath, neck pain, and irritability will go away all together. Going to give it a full six weeks and see then. Haven't noticed any weight change, but have noticed reduced appetite and cravings for sweets. F 38 9 days
11/7/2005

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