WELLBUTRIN XL Reviews (BUPROPION)

Average Rating: 3.4 (1462 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN XL  (BUPROPION):  This medication is used to treat depression. It may also be used to prevent seasonal affective disorder (SAD), a type of depression that occurs each year at the same time (for example, during winter). This medication can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2003-08-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN XL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN XLCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Depression/GAD When treatment first started (ramping up), I had a few foggy moments where the words would be on the tip of my togue, but got them out a bit too late. Songs I knew for years, I would blank out on the some of the words. This went away. I was only on 150mg. Never split the pill in half or break it (they aren't kidding on this one). I accidentally bit into one, and spit it out immediately. M&Ms in one hand, pill in the other (got confused trying to rush and take it at my desk). That instant on my tongue went into my bloodstream and caused a dizzy effect that made me have to call my husband to pick me up from work right then and there. It lasted for 4 hours of head tingling and the feeling like I was falling backwards. I highly recommend this drug. I had never been on any antidepressant before, but needed something while going through a divorce. I'm only 105 lbs, so the 150mg (half dosage) worked for me. I only tried the full adult dosage of 300mg once (one day), and it was NOT for me. I felt like the left side of my head was tingling and had to leave the grocery store. I did not have a problem ramping down off of this when my doctor and I felt the time was right. It was a breeze for me, and I feel bad for those who struggle to find the right medicine, and for those trying to ramp down on really addictive ones like Lexapro and Paxil. I have had to go on and off of Wellbutrin a few times over the last several years due to various life changes (deaths, family drama, etc). F 39 5 years
12/18/2006
 5  Depression after Trauma None Had been on Celexa and Lexapro for several months with not much improvement. Dr. added low dose bupropion. Then Switched me to Wellbutrin XL and currently weaning off Lexapro. I will have to say I feel better now than I have in the past 6 months. M 48
12/18/2006
 5  dysthmia, anxiety, ADD my post below got cut off but this is the info that led me to this board in the first place. And I couldn't exactly ask my doctor or the CVS pharmacist about this stuff! Also, this is probably bad but I still totally drink and smoke pot. I only drink socially [maybe 3 drinks once a week or so?] but I haven't noticed lower tolerance or weird side effects. Pot doesn't effect me as strongly tho. [lame.] I was really scared to drink or smoke pot at first b/c of the things I read. I recommend just starting off slow [like one glass of wine] and see if you feel any different. F 30 6 months
12/14/2006
 5  Dysthymia, anxiety, ADD Constipation [i recommend a fiber supplement or eat whole grains at least once a day] & Dry Mouth [drinking more water is always a good thing anyway]. Maybe the excess water consumption aids in the weight loss? this drug pulled me out of a major slump. I feel back to myself! In the last 3-4 months, I've left a dead-end relationship and lost 25 lbs. I'm active again and eating healthy. I'm thinking about my future in ways I hadn't in a long time. I've never taken a mind drug before so I can't compare to Prozac or whatever. But I've always sort of buried my emotions. With W-XL, I'm very aware of my emotions. I cry when I'm sad or feel angry when I should. I really contemplate before I act -all ways of being that weren't always that natural. I've discovered many things about myself since on this stuff. Might not be entirely due to the WXL, but it def. hasn't hindered my emotional growth. Who knows - maybe i'm just growing up finally!? at first, I was on generic 150mg 2x a day. Dr. switched me two months ago to 300mg XL - even better, more noticeable results! Also, this is probably bad but I still totally drink and smoke pot. I only drink socially [maybe 3 drinks once a week or so?] bu F 30 6 months
12/14/2006
 3  depression, anxiety noted decrease in appetite, insomnia, feel "wired" and unexplained crying spells After years of self-medicating w/illegal herbs, I found myself at the gravity bong ALL the time!! Then, when at the Dr's office for a cold, I broke down into tears. Long story short, dr. prescribed Wellbutrin XL 300 mg 1x daily. The first 2 days I had so much energy that I could not rest during the day when I should have been due to illness. I have had quite a time trying to sleep at night; hope it passes. I am experiencing pain in my neck and shoulders as well, but I had not linked it to WB until I read some posts here. I haven't had much of a desire to smoke, but I'm sick, so we shall see. F 29 3 days
12/14/2006
 3  anxiety & depression hot flashes, too! p.s. I forgot to mention that I did not tell my Dr. about my herb addiction! F 29 3 days
12/14/2006
 5  depression some itching, appetite suppresant, I think I have lost weight but my tummy is getting flatter anyway, some mild insomnia, I feel like I am taking ephedra since it has a "speedy" effect I started with XL and that is what is working so far. 75 in the morning and evening 12 hours apart for 3 days, now I'm at 150 once a day and tomorrow I will do 300 a day. So far I have felt so much better and happy and like myself. An earlier post described the "doomed" feeling being gone when waking up.. I have that feeling too.. happy to wake up now, and don't want to just stay under the covers and hide F 41 9 days
12/13/2006
 5  Depression One side effect I'm having, that I was wondering if anyone might have any suggestions as to how to improve, is that I can't seem to drink any alcohol at all. I've been taking Wellbutrin for a few years now and used to be able to have one or two drinks every so often, but can't anymore - I feel like it's like alcohol poisoning or something. Anyone have any suggestions? I like Wellbutrin enough to stick with it, but I'm wondering if maybe I skip my dose (150 mg) the day I'd like to have a glass of wine if that might help. I don't drink very much but do enjoy socializing with friends occasionally and would like to still be able to have a glass of wine once a month or so if possible. F 43 3 years
12/11/2006
 4  Depression,anxiety,smoking,bingeing The first year just dry mouth,mild constipation,occasional difficulty sleeping (150mg SR). I then felt so much better that i went off of it for 3 months. I just got back on it (300mg SR) and now i'm getting severe chest pain/tightness, the worst panic attacks I've had in my life. I never truly,truly felt that I was going to die during a panic attack until I started taking the wellbutrin this time around again. It's scary, and weird that i'd be having this reaction now but judging what people are saying, it probably is the wellbutrin. i think that I jumped up to 300mg too fast, but this chest tightness and horrendous anxiety are enough to make me switch to something completely different. Keep in mind that this drug is illegal in several other countries. But when it works, it works damn well F 22 365 days
12/11/2006
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 3  Depression Difficulty in sleeping and appetite loss the first week. Vivid dreams. Ringing in my ears. Definitely reduces desire for cigarettes, and those that I had tasted terrible. I'm just crossing the 2 week threshold at 300 mg / day. I do feel better in general, though I continue to have some "down" points. Certainly better than without. I'm hoping for a more level feeling. I'm also surprised at the number of orgasms I have daily - it is somewhat inconvenient to address. M 14 days
12/11/2006
 1  GAD Depression Inappropriate IRRATIONAL anger. Become completely engraged at nothing. Hypersensitive and this magnifies everything - mild PMS becomes unreasonable PMDD, hunger pangs become an agitated all out search for food! Caffeine-like surges (in a bad way) Rash all over my back of small pimples. Confusion and memory loss - terrible. Cannot drink alcohol without flying into a rage. I rated this a 5 after 10 weeks. Seemed great at first - then it totally turned on me. I am angry, moody, irrational, confrontational and MEAN. This makes me so unpredictable that I have been staying away from people for fear I may flip out. I have had inappropriate outburts at work. I have NEVER had a temper. And I cannot lose a pound of weight to save my soul. If you are getting AGITATED, angry and irritable it is not you it is the Wellbutin - BEWARE! F 35 6 months
12/11/2006
 2  fibromyalgia/ CFS/ mild depression For the first 10 days I experienced a mind splitting migraine like headache that was not helped by any OTC pain reliever. The last 4 days I was on the med (14 days total) I had a mild headache. Slight upset stomach, loss of appetite (when I did not eat I felt sick) dizziness, medicine head, moderate anxiety, loss of libido, very aggitated, hot tempered, insomnia, increased depression. My doctor prescribed this medicine for me as I have chronic fatigue syndrome or Fibromyalgia (she has not clue what is the matter with me lol) as well as reactivated mono. She thought this would help me. I really tried to remain on this med for a month, but after 2 weeks I had to stop. For the first 3 hours after I take the 150 mg pill in the AM I feel shaky and really did not feel comfortable driving. After a couple days I was becoming paranoid with anxiety, sad, moody, and very snappish at my family. I just felt like my blood pressure was increasing all the time. I did get a little more energy in the mornings and did not run to the coffee pot. I am sensitive to medications as I do not take any regularly, and I think that I was just one of the people who did not benefit from Wellbutrin at all. All the side effects, or maybe the meds themselves, made me feel very sad and out of control of my life and body. F 29 14 days
12/10/2006
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 5  Depression, Libido Well I tried this med at 100mg Wellbutrin SR per day and felt results right away first few days. Was more focused, happier, more confident etc.. However By day 5 I started having Drastic Mood Swings and a Mini Panic Attack First time in my Life! Now I realize that for Wellbutrin SR to work properly it needs to be combined with an SSRI. If you take Wellbutrin SR by itself it'll be good at first but eventually it's going to cause massive anxiety and panic attacks , insomnia. HOWEVER when you combine it with an SSRI like Prozac YOU GET MAGIC. Wellbutrin SR + Prozac you get MAGIC! All the side effects of wellbutrin are cured by Prozac and all side effects of Prozac are cured by Wellbutrin. PURE MAGIC. NEVER TAKE IT ALONE never take prozac or wellbutrin alone. Always combine them(Serotonin - Dopamine and Epinephrine) You need ALL 3 not 1 and not 2. ALL 3 OR NONE. Well I tried this med at 100mg Wellbutrin SR per day and felt results right away first few days. Was more focused, happier, more confident etc.. However By day 5 I started having Drastic Mood Swings and a Mini Panic Attack First time in my Life! Now I realize that for Wellbutrin SR to work properly it needs to be combined with an SSRI. If you take Wellbutrin SR by itself it'll be good at first but eventually it's going to cause massive anxiety and panic attacks , insomnia. HOWEVER when you combine it with an SSRI like Prozac YOU GET MAGIC. Wellbutrin SR + Prozac you get MAGIC! All the side effects of wellbutrin are cured by Prozac and all side effects of Prozac are cured by Wellbutrin. PURE MAGIC. NEVER TAKE IT ALONE never take prozac or wellbutrin alone. Always combine them(Serotonin - Dopamine and Epinephrine) You need ALL 3 not 1 and not 2. ALL 3 OR NONE. M 25 30 days
12/8/2006
 1  reduce anxiety & menopause symptoms Experienced insomnia, depression and anger. I took Wellbutrin SR (450 mg) for years with very positive results. My MD switched me to XL because the manuafacuter says that scripts above 300 mg should be XL rather than SR. This is not true in actual practice. I checked with a respected psychiatrist and was told it was fine to stay on SR even at the higher dosage level. If you have good results with SR do not assume you will have a smooth transition to XL. SR can be taken at the higher (450mg) dose once in the morning and pass through your system during the day so you do not experience insomnia. XL provides less support over more time and, for me, resulted in increased anxiety and no sleep. Lack of sleep worsened my problems. I believe the push for swithing to XL is about cash in the manufactuers pocket. SR is available in generic and XL is not. MD's not fully experience in perscribing anti-depressents may be defaulting to the hype rather than perscribing based on experience. F 47 30 days
12/5/2006
 5  Depression & PMDD Constant sleepiness, inability to stay asleep at night, very vivid dreams, increased irritability and anger, feeling spacey, so far the only good side effect has been increased libido! I was switched from Prozac 20-mg daily to Wellbutrin XL 300-mg daily due to the weight gain I experienced from Prozac (50 pounds in 6 months). Prozac worked (for me) to keep the irritability and anger I experience daily at bay. Unfortunately there was the decreased libido and crazy weight gain to deal with. My doc decided to try Wellbutrin. It has been a month and I have yet to see any weight loss as a side effect, but my temper, irritability, and anger have rushed back. I am unable to stay asleep at night, but when I do sleep, I have dreams so vivid I thought I was actually awake and actively participating. After reviewing most of these opinions, I can't really tell if anyone that had the same issues I am having have had them go away. I am really ready to switch back to Prozac and deal with being fat. Feel free to email and let me know! F 27 1 months
12/4/2006
 5  Depression Trouble sleeping, strange dreams, nervousness. I was on Effexor XR for 3 months (75mg) and had no results except extreme fatigue. Switched to Wellbutrin for approx. 10 days now (150mg) and except for some side effects listed above, i already see improvement in mood. I hope insomnia and nervousness will decrease with time. M 25 10 days
12/3/2006
 2  Combat depression; increase libido Trouble sleeping,very low lows (to the point of nearly breaking down and sobbing) more frequent and much more intense suicidal thoughts,DECREASED LIBIDO,greatly reduced alcohol tolerance,unusual and unexplained itching,feelings of uselessness,hopelessness,why care about anything,etc. There has to be something (probably anything) better out there. Plan to request change back to Prozac ASAP. M 63 10 weeks
12/3/2006
 4  depression i did experience light headedness,,felt very hyper,,no appetite which i liked,,had a little trouble sleeping at night,even though i took first thing in morning,,made me also feel very hyper, cleaned my house, felt like i drank 40 cups of coffee,,it did help my depression though i dont want to take this the rest of my life and i think dosage was too high at 300mg,,would recommend for depression and energy M 48 7 days
12/2/2006
 2  Depression/Anxiety Rash and INTENSE ITCHINESS, Tinitus, irrational anger, headaches. Initially had terrible anxiety but that went away adter the first couple of weeks. FOR ME--too many side effects and not enough benefit. Very successful for my sister. WHAT A RELIEF TO SEE I'M NOT THE ONLY ONE WITH MY SIDEEFFECTS!! Normally I hyper research a drug before I take it, but this time decided against it to not influence any reactions I may have. BIG MISTAKE!! Had I known the possible, normal side effects I could have saved my self a lot of time and physical suffering. Wellbutrin (XL - 300 mg) was very successful for my sister so I was switched to it from Effexor (300 mg). I'm calling my shrink today to go off it. The itchiness has now progressed to swelling in the hands and feet, and to make my depression SO much more fun I'm now breaking our in a hideous rash all over my body. The tinitus is getting unbearable. The irrational anger I had before going on various medications over the last ten years has come back with a bang, as well as the headaches. F 41 3 weeks
12/2/2006
 5  smoking, depression The first five weeks were difficult. Agitation, some sleeplessness, hot flashes. Wanted to quit. Thanks to this website I hung in there and I'm so glad I did. Almost five weeks to the day the bad symptoms disappeared. Now I have perfect clarity and an incredible energy level with no agitation. Sleep well but wake up ready to go. Stopped smoking, no problem. Lost weight. I encourage people to hang in there. It's tough the first month but well worth the effort of waiting 'til the brain chemistry resets itself. Hope it doesn't wear off! F 52 3 months
11/30/2006

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