WELLBUTRIN SR Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.5 (997 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN SR  (BUPROPION HYDROCHLORIDE):  This medication is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2002-06-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN SR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN SRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Bipolar 1 insomnia, loss of appetite, extreme anxiety I took the generic bupropion and the side effects were terrible. It did take away the depression within days but I would wake up 10 times per night even though I am taking tamazepam to sleep. I completely lost my appetite and lost 5 pounds in one week. I could force myself to eat but the insomnia was unbearable. I usually take the tamazepam occasionally but I have had to take it every night with this medicine. I have been off it for 3 days and I still cannot sleep without the tamazepam. The anxiety is terrible. I am scared to leave the house or be without my husband. The anxiety is lessening but it is still there 3 days after I stopped taking it. F 31 7 days
100 MG 1X day
2/27/2011
 4  Stop Smoking Fogginess has decreased,dreams are still vivid Prescribed to double the dose after a week,twice a day, still smoking a few, but it's making it easier to put them down. I work in a bar that still allows smoking and I am noticing how bad they smell to me.So far so good. M 48 13 days
150 2X day
2/23/2011
Patient History
 4  Depression, Anxiety, So far the side effects are min. I had orriginally the shakes, grinding teeth, and excessive energy. However, they went away fairly quick. I was suppost to go up to 150 x 2 day. Once I did that I got a terrible Ringing in the ears. I called the doctor and went back to 150 x1day and the ringing has gone down way down in just a week and is slowly going down, Decreased appetite, Very nice dreams, Slight head pressure if I don't take it on time. I am taking Bupropine 150 sr. 150 mg x 1 day. I started 3 weeks ago and the side effects were minimal. When I increased the dose I notice ringing in the ears, and a slight head ache. Apparently that was too much for me as I went back down to once a day and it has subsided. I already feel much better. I had no idea I was depressed until the doctor gave me an evaluation. I knew I was plagued with anxiety, but never would have guess that it was also depression. I didn't want to play with my new born daughter, even looking at my husband made me sick (I know so sad) and I wanted to sleep all day long! after about 3 doses I had so much energy, after about a week I was waking up before my alarm clock, and now its leveling out but still feel like a weight off my shoulders. I am a mother, full time student, full time worker, and a wife so I really had a lot on my plate I guess. I am slowly getting off of Zoloft as that cause me severe weight gain (I am on weight watchers for the longest time and was always 125-137lbs) now I am 162 with consistant weight watchers diet! Just kept gaining and wanted to eat everything in sight. So far I have not lost any weight on buproprine however, My appetite is so low that I have to remind my self to eat. I think its just taking time for the zoloft to get out of my system as I was on that for 2 years. I am down to 50mg 1x day zoloft and should be off of it with in a week or so. I will keep you posted I am hoping that my weight does come down. F 25 3 weeks
150 1X day
2/11/2011
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 3  bipolar/depression/anxiety Major lack of appetite,(losing 5lbs a week). Not healthy in my case because of recovering eating disorder, and not to mention that I'm now underweight. I have to remind myself to eat throughout the day because I'll forget! Feels like I have no sensation in my stomach, can only hear it growl. And when I do eat, it's very small portions. I have noticed some constipation and bloating, but I think that's subsiding. I felt like I just wasn't digesting correctly for weeks! Has anyone experienced any lower back pain? I've been dealing with that since starting the medicine, but not sure if it's associated... I first started Wellbutrin SR at 75mg for 3 days, then increased to 150mg for 3 weeks. I had no cognitive side effects-if anything I felt that my brain was able to function better and concentrate. I noticed a slight positive change in my overall mood, but nothing significant. 150mg is kind of a low dose, and it had only been a few weeks so I figured I wouldn't give up quite yet. One thing to remember is that every medication works differently for every person. I think that metabolism, body weight, what kind of illness all are factors in determining when and if it will work. Don't knock it before you try it. So after the 3rd week on 150mg, my dose was increased to 300mg XL in the am. I took this dose for 3 days and felt completely delusional, irritable, anxious, extremely lethargic. I called my Dr and she told me to go back down to 150mg for now until I felt better. I am quite sensitive to medication, so titrating for myself will take some time. I haven't experienced any sexual benefits or side effects, insomnia or dry mouth so far... Believe me, I felt like giving up into the 4th week thinking it wasn't going to work, but I'm going to stick it out a little longer. If you're feeling discouraged don't give up yet! Sometimes we have to endure the bad before we are able to reach the benefits. I will update in a few weeks and share any progress. Hope any of this into helps! F 22 4 weeks
150 1X day
2/2/2011
 1  Depression I ONLY took this medication for 5 days. On the first day I experienced dry mouth. On the second day anxiety. On the third day I started having major side effects such as TOXIC OVERLOAD (LIVER AND KIDNEY PAIN), HEADACHE, anxiety, chills, and head fog. I stopped it and detoxed my system with herbal tea, water fruit and veggies. I feel 100% better! My best advice is to stay far away from Wellbutrin SR and try XL instead! If XL doesn't work, stay far away from this medication period!!!!!!!!!! I only took this medication for 5 days. I had to discontinue use do to Toxic Overload and Migraine! I detoxed with herbal detox tea, water, fruit and vegetable smoothies, and now I feel 100% better! My advice is to try Wellbutrin XL, and if that doesn't work for you, stay far away from Wellbutrin SR!! F 30 5 days
150mg 1X day
1/28/2011
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 3  mild depression, mood swings Days 4 & 5, no side effects. But on day 6 I was very constipated. I counteracted it with a laxative. Have had a headache and upset stomach for the last couple of days. F 43
150mg 1X day
1/13/2011
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Patient History
 4  Smoking Cessation Dry mouth, constipation, tremors, loss of appetite, sore joints, muscle aches, "foggy" mind (1st wk), anxious, overly happy, migrating hives, no loss of libido, increased sweating I experience the usual side effects, dry mouth, constipation, slight tremors. What I wasn't prepared for was the migrating hives on the 2nd week. I would get hives in one spot on my body, itch for about 20 min, then it would stop itching and move to another area. On my 3rd wk, the hives stopped, but the muscle aches and joint pain started. It feels like someone charlie horsed every major muscle in my body (arms and legs). I have a generalized weakness throughout my body also. F 33 3 weeks
150 mg 2X day
1/11/2011
 1  depression interstitial cystitis or chronic bladder inflammation I believe this medication caused chronic bladder inflamation. It damaged the lining of my bladder. It is called interstitial cystitis and it may be a permanent and painful condition. It feel like you have a urinary tract infection, but it could be permanent and progressive. Now many things irritate my bladder tht didn't before. I can no longer drink coffee or alcohol. It feels like I constantly have to urinate. I had no idea this drug could do this much damage. It just says "frequent urination" for side effects. It doesn't say it could be damaging your bladder. I got a generic from Sandoz labs. Not sure if that makes a difference or not. M 53 60 days
150 2X day
1/8/2011
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 4  Depression The first week I took the medication I didn't feel any effects at all. Going on day 10 or so I started suffering from severe insomnia. I could only sleep for 3 or 4 hours a night and it was extremely difficult for me to even be able to fall asleep for that long. I was tired and wanted to sleep but my body wouldn't let me. After a couple days of the insomnia I started feeling like I was high all the time. I felt totally out, had a ton of energy randomly throughout the day, couldn't concentrate and had severe dry mouth. These effects lasted for about a week and then slowly disappeared. The only lasting effect of the medication is decrease in appetite. Medication helped a lot with my depression. The only tough part was making it through the couple weeks of awful side effects. F 18 6 weeks
150 MG 2X day
12/28/2010
 2  Depression / Apathy A little nervousness. Insomnia. Drowsy shortly after taking. Total sexual dysfunction. I started this to help with some depression and general apathy, along with some sexual dysfunction issues. I was lead to believe Wellbutrin would not cause libido or erectile problems. So far, my depressed mood and apathy remain unimproved, and sexual dysfunction has gotten dramatically worse. It just doesn't seem to be doing anything positive. M 47 21 days
150 2X day
12/24/2010
 5  I started taking it to quit smoking Dry mouth, constipation, ringing in ears but went away quick, vivid dreams I am on the generic brand, it has helped me alot, I am the kind of person that doesnt take pills. I started this for quiting smoking and found that it took all my anxiety away, and my emotional outbursts were gone. I thought this was just part of my personality all these years and come to find out I was depressed. I can concentrate better, think better, less emotional, focus alot better. And my moods stay even. My mate definitely can tell the difference. I would get mad at the stupidest things and was super sensitive. Now the things that bothered me seem to roll off of me. I also dont have racing thoughts anymore. I thought this was how life was supposed to be and wondered why everyone else seemed so happy and I didnt. But being on Wellbutrin Sr 150mg twice a day has made a huge difference so far and I am going to ask my doctor to put me on this all the time. F 38 3 weeks
150mg 2X day
12/6/2010
 5  Depression Dry mouth & a 'spacey' feeling sometimes. No appetite. Doctor prescribed this for depression & inability to handle daily stress. Days 3 & 4 I accidentally took 2 pills, which really brought on the dry mouth, but I had lots of energy, almost manic. (Sometimes I feel 'spacey' but it only lasts a few minutes.) I feel great on this drug and I lost 5 lbs. the first week, which makes me feel great all by itself. In the past I've been on Elavil, Celexa, St. John's Wort and Lexapro; the latter of which made me gain 40 lbs. in 1 year. I already feel more calm & stable, plus I have a lot more energy. I love this drug and if I continue to do well I plan to stay on it forever. F 49 10 days
150 mg 1X day
11/29/2010
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 3  Depression Day 1: Nausea pretty much all day except when eating (which is weird right) Day 2: Nausea, sleepy, Vomiting, Diarrhea, joints hurt... FLU like almost, no change in mood Day 3: Nausea, sleepy, Diarrhea, mild joint pain Day 4: Mild Nausea, Mild Sleepy, TOTAL DIARRHEA!! Day 5: Mild Nausea, slight headache I am sharing my first 5 days because if I wouldn't have read other peoples reviews on this website, I would have stopped taking. I understand that it is typical for anti depressants to take 4 weeks to full potential so far I have not felt any change in mood/mental well-being. I am still eating food because it makes my stomach feel better, I have lost 6 pounds with all the vomiting and diarrhea. It is a must to drink lots and lots of water. Day 5 feels a lot better physically ... That's pretty much what I wanted to share because I could not find infomation on time frame for this nausea/vomiting to end. I dont know if my body just needed to get use to the drug or maybe the Nausea and vomiting are taking a break. (I had a normal BM today (i know you're welcome) I will update later I just wanted to get my physical experience out there. Also I am to afraid to increase my dosage to the 2 a day, I have only been doing the 150mg once a day. (and my sexual interest has perked just a hair but maybe that's all the talk about the increase has me happy) F 32 6 days
150mg 2X day
11/22/2010
 3  Low Libido I have nausea,decreased appetite,ringing in ears,constipation,dry mouth, crazy wild dreams and insomnia but that is slowly becoming less. It seems similar to the side effects of Chemotherapy? This is what I hope will turn me back on. I typed 7 days but for 7 days before that I was taking the generic from Watson and I never felt so bad in my life, I was like is this worth it? It is because the person in my life has been so patient and she means the world to me. It took like an act of congress to get the brand name and I still paid almost full price. It is significantly better with the side effects still got them but not nearly as bad. Thanks for the Canadian idea! Got to try that or go broke. Call me inpatient but when should it start to work? It seem for the older (40's) users on this site it takes a bit longer? It definitely is working in my sleep I wake up ready to go. M 45 7 days
150 2X day
11/20/2010
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 1  anxiety Started with nightmares, advanced to strange giddiness, elevated heart rate, ringing ears, extreme anger and aggression, bad anxiety attacks, and paranoia. Was taking Zoloft for 8 years for anxiety (social and GAD). Gained weight at first, but took most off. Weight plateaued for 6 years despite constant dieting and long-distance running. Switched to Wellbutrin to try to rev metabolism and lose weight while controlling anxiety. Didn't lose or gain, but became the anxious person that I didn't want to be. Had some of the worse anxiety attacks of my life 4 weeks after starting Wellbutrin. At 10 weeks I gave up and am coming off Wellbutrin. I am still feeling moody but it is more controllable than while on the 150 mg of Wellbutrin. F 34 75 days
150 1X day
11/20/2010
 2  Depression and Anxiety Tiredness, more depression, foggy/dizzy feeling I only took this for three days but that's all I can stand. I was so tired I felt like I'd taken a sleeping pill, and was dizzy and kind of disoriented. Plus, I felt just as depressed if not moreso. F 37 3 days
75 1X day
11/8/2010
 3  Anxiety Loss of appetite, nausea, vomiting, weight loss, horrible insomnia, jaw clenching/pain At first I was thrilled about the weight loss, even though I'm not overweight, who doesn't love to drop 5 pounds without really doing anything at all? I am really almost never hungry and I have to sometimes force myself to eat. One three recent occasions I have eaten large meals and then threw them up. I've been unable to sleep through the night, no matter when I go to bed. I usually wake up between 2 and 3:30 and am wide awake, unable to fall back asleep. Taking xanax before bed does not help. Drinking a bottle of wine before bed does not help either. Most recently I've noticed that the left side of my jaw is so sore. I guess I'm clenching my teeth at night. F 28 7 weeks
150 mg 2X day
11/5/2010
 5  Bi-Polar II with depression Lightheaded, mild insomnia. Clear head, energy, improved libido. F 48 10 days
150 1X day
10/28/2010
 3  depression 1st few days - Sleepy, funny taste in mouth .. Only slightly jittery - BIG decrease in hunger and desire for food and pain meds. I have high hopes for this med to work. I've taken Cymbalta, Prozac, Efexor, Lithiam .. Cymbalta worked great this first time I took it .. Then I became pregnant and stopped cold turkey. What a nightmare! After giving birth, I went back to Cymbalta for 7 months with no improvement. Switched to Prozac and only slight improvement. So here I am with Wellbutrin SR - High hopes! F 40 3 days
150mg 2X day
10/27/2010
 4  Depression Insomnia So far this is working for me. I feel much better, more focused, and as a result, I actually am enjoying life. At times, I feel a little weird, but the overall effect is improvement in my mood, attitude, and life. I will update at a later time after further use. F 35 5 days
150 MG 1X day
10/19/2010

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