WELLBUTRIN SR Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.5 (997 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN SR  (BUPROPION HYDROCHLORIDE):  This medication is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2002-06-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN SR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN SRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Severe Depression Insomnia, energy bursts, tingling effect in lower body 10-15mins after taking pill. HUNGRY...SO HUNGRY! *TAKING THE GENERIC TEVA BUDEPRION SR* My stomach growls immediately after taking pill and all day after. A deep hungry type pain. And my stomach is so loud now! Also, it makes me feel like I need to be by myself. I don't really want to be around anyone. :( I don't think this is working for me yet. F 26 4 days
150 2X day
4/12/2010
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 5  quit smoking See comments I had a heart attack in January, 2004 and was advised to stop smoking. I was 59 at the time and had smoked since I was 13. I had tried to quit many times over the years with no success at at. I had tried everything - acupuncture, hypnosis, cold turkey, nicotine gum - everything. In June, 2004 I asked my doctor to prescribe Wellbutrin and let me see if it would help. I smoked my last cig on Speptember 3 and have never had the slightest urge to smoke since. I consider that miraculous! It occurred to me at the time that I had not been at all depressed since I had begun taking the Wellbutrin. I had suffered serious depression in fairly regular monthly cycles since I was a teen. I told this to my doctor and we decided for me to continue the Wellbutrin as long as the results were acceptable. I can honestly say that I have not had a depressed moment since I began taking the medicine in 2004! I have now lived almost six years experiencing the life that most take for granted. Only someone who has lived with depression would understand - my life has been changed beyond my ability to describe. Never a day goes by that I don't think of the almost fifty years of hell I lived through. I only wish everyone could have the results with Wellbutrin that I have experienced - truly miraculous! M 65 6 years
300 mg 1X day
4/9/2010
 5  depression decreased appetite and need for sleep. I lost 35 pounds in 6 months by using the side effects decreased appetite as a motivator to lose weight. Effexor helps with depression and anxiety but the added Welbutrin seems to brighten my dispostion as opposed to all other drugs took away sadness and despair but Welburim added sense of happiness. F 41 10 months
200 2X day
3/29/2010
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 3  Depression, anxiety Dry mouth, anxious pit in stomach, wordfinding problems, occasional shakes I've only been on Wellbutrin SR for less than a week and already I can see an improvement in my thinking. The depression isn't so bad and I can fight/reason with the negative thoughts more easily. However, I feel it's harder for me to communicate verbally, although that might be just general fatigue (I work continental shifts) or me going off Paxil (I'm currently at 4mg/day on a titrating schedule.) I would really advise anyone taking ANY antidepressant to also talk to a therapist/psychologist. While depression has a bio-chemical basis, it also has a mental basis. It's important to learn how to think things through properly and deal with the negative thoughts when they come back. M 36 5 days
100 mg 1X day
3/28/2010
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 1  Depression I do not like this drug at all..I feel more depressed since taking it than I did before....all I do is cry..cry ..cry. I am angry all of the time...I bite people's heads off ...it is HORRIBLE...dr. increased to 2 pills per day after a week...made everything WORSE I do not like this drug at all...If I weren't nuts before...I certainly am now. I cannot face people...I won't go shopping for groceries...and when I have to..I avoid everyone I can...Cry...Cry Cry... F 47 4 weeks
150 1X day
3/16/2010
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 4  Mild depression Mood swings, vivid dreams, insomnia, dry mouth, short-term memory loss, nausea, anxiety. Did NOT experience weight loss or gain. The stabilization period was absolutely wacky - all the side effects above, including mood swings from REALLY REALLY HAPPY!! to the most depressed I had ever been in my life. When I went back to my doctor to check in, I wasn't sure that I wanted to continue with it, but we decided to give it one more week. And I'm so glad I did. On day 15, it was like somebody had flipped a switch - the dry mouth and all the other side effects were gone, and I was happy and mellow and feeling much more myself again. Also, my sex drive has come back (yay!) Definitely worth sticking it out through the stabilization period, and everything is working well now. F 35 21 days
150 mg 2X day
3/15/2010
 1  depression I felt fine for the first 4 days and then ... onset of Severe anxiety, Panic Attacks, Fear, Increased Depression, Dizzy/off-kilter feeling, Thoughts of doom, Could not eat at all(lost 5 lbs in one week), Diarrhea, Shaky Feeling, Crying all the time (including one full day morning till night), Vivid and prolific dreaming. This was an absolute nightmare ... a horrible, horrifying and very, very scary experience. I usually have a fairly mild depression that ocassionally worsens after a difficult period. This medication made me feel like a complete mental case!! I can now understand how some people end up committing suicide after starting a new antideppressant ... it made me feel about a thousand times worse. Please be very careful if you are trying this medication!!! F 37 11 days
150mg 1X day
3/15/2010
 3  depression, anxiety, smoking insomnia, depression, paranoia i've had depression and anxiety since i was 12. i never took any medication until i was 20. took many ssri's without any luck. the weight gain was horrible so i stopped taking them. i had been off anti depressants for 5 years until i decided i'd give them another shot. wellbutrin has changed my outlook on life somewhat, but it's only been 6 days. i'll post again after 6 weeks. M 25 6 days
100mg 4X day
3/7/2010
 4  quit smoking/anxiety the 1st week I had severe mood swings//anger outbursts! I have felt so spacey and like I can't talk--even when I need to talk such as in my college classes when my Prof. asks me a question! I also can't stop moving my hands/arms/legs for a couple hrs after taking it--so now I take it in the evening-it's embarressing at school ! I have also lost 5 lbs in 2 weeks! I love how it makes me not want to eat and also my OCD is back BIGTIME! All I do is clean like a fiend and exercise--I love the energy !! The only bad thing is that I smoke even more now! I am so anxious and nervous that I smoke more :( F 40 14 days
150mg 1X day
3/6/2010
 1  Anxiety Increased anxiety; Suicidal Thoughts; Uncontrollable Emotions: could not stop crying, violent mood swings; Unbearable Insomnia ( I am posting this at 4am and haven't fallen asleep yet despite 2mg of Xanax). I was on Celexa for 1 year and had to stop due to an marked increased in migraines. Switched to Pristiq which was great at first with the plus of weight loss, but then I started getting depressed and gaining weight and having sexual side effects which I never had before. Tried Wellbutrin SR 150mg and feel like I'm going off the deep end. Doctor is tapering me off and are going to try Buspar, but the side effects of that are not going much better. F 39 6 days
150 1X day
3/4/2010
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 1  Depression Gained almost 10lbs on this, increased appetite, no energy, no libido whatsoever, made me angry, extreme anxiety, awful drug for me. I did not like this drug at all. It seems to have the opposite effect on me than most people. I was on Celexa which was working for me, but made me sleepy. Doctor switched me to Wellbutrin to see if that would help. It did not. It increased my hunger, I gained 10lbs (and I excercise 4 times a week), and absolutely killed my libido. Celexa did not do this for me. It also made me extremely agitated and angry, both which are not normal for me. I was so tired all the time, didn't want to do anything, but cry and stay on the couch or in the bed. It killed my motivation. I was like a different person. I work full time, so this was not good for me. I went back to the doctor, who said I needed to increase my dosage from 150 mg to 300 mg daily. This only made me worse, even more agitated, sleepy, angry, hungry. Hell. Called doctor and and told him I wanted to go back on Celexa after 2 months of hell with Wellbutrin SR. All these side effects disappeared once I stopped taking this drug and went back to Celexa. Celexa made me sleepy, but not to the point of being where I couldn't get out of bed or do anything. I got back to normal, and lost the 10lbs quickly. Never changed my diet during the course of this drug. I eat low fat, healthy, and excercise. Won't ever touch this drug ever again. F 28 2 months
150 mg 1X day
3/3/2010
 5  Major Depression/Smoking Cessation Short term(only lasted a few weeks): nasty taste in mouth, drastic weight loss, nausea, headaches, constipation, violent mood swings, irrational irritability, heart palpitations. Long term: hand tremors (not persistent), insomnia, lack of appetite, occasional nausea (could possibly be attributed to multi-vitamin I'm taking), increased sex drive. No longer depressed. Feel optimistic about future. I also have much more drive and energy to get what I want accomplished rather than just thinking about it. I feel happy almost all the time! Weight loss has tapered off which was good because I was thin to begin with - I lost 3 lbs in the first two weeks which doesn't sound like much but considering I am 5'6" and 115 lbs (now 112), I can't afford to lose an ounce. My appetite is still non-existent, but I just make myself eat at regular intervals and I do fine. Best of all - I quit smoking! The cravings are gone and even the smell of smoke makes me gag (husband still smokes - I'm gonna kick him outside to smoke when the winter is over). This really is a wonder-pill! F 32 60 days
1/28/2010
 4  Depression Bad taste in mouth, anger, insomnia, energy, weight lose, shakes, depression worsened Week1-bad taste in mouth began, had tremors and shakes the first 3 days only, couldn't sleep more than 2-4 hours a night (I usually sleep 7-8), and I noticed a wanting to distance myself from others (took all I had to go to work around other people) week2-bad taste still there, Extreme/irrational anger bordering on rage, sleeping better/more, withdrew from friends and family (only left my house for work and only talked when I needed to). Doc had told me to give it at least a month, maybe 6 weeks. At the end of week 2, I woke up one day feeling a little bit more like normal me....and the anger was gone. The next day was so much better! The only side effect now is the bad taste in my mouth. Food doesn't taste bad, just my mouth. OH! And weight lose. Been on celexa for years with about 40lbs weight gain and inability to lose no matter how hard I worked at it. Now I'm down 16 lbs!! Weight lose was a lot the first few days and has leveled off to a lb every few days. I really thought I was going to have to quit it after the first two weeks. I'm really glad I stuck it out. I feel normal again. F 43 18 days
1/24/2010
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 2  Major Depressive Disorder Sleeplessness, headaches, dry mouth, more intense thoughts of suicide I haven't gotten a good night's sleep since I began taking this medication. I was on Wellbutrin several years ago for the same reasons and my side effects were much less negative. It also seemed to kick in faster and in general I responded well to it. I am not so sure on this go around, but I'll keep at it for a few more weeks. F 23 10 days
1/17/2010
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 2  anxiety/depression light headed and dizzy, nausea and vomiting, bad headache, shakiness, some difficulty urinating. I have been on Zoloft, 25-50mg for about 5 months, which took awhile to kick in (second month) but worked great over time, and I continue to notice new improvements. My problem is weight gain, about 7lbs and climbing and is not coming off with diet and exercise, (I'm a dancer and cant afford this) and jaw clenching(which was tolerable). I'm switching to Wellbutrin SR 150mg(generic) so I can feel good without getting chunky. I'm doing 150 once a day for one week while still taking the Zoloft, then quitting the Zoloft and supposed to be going up to 300mg of the Wellbutrin (150, 2x daily) on week 2. This is my second day. I took meclazine (over the counter- I checked with the pharmacist who said it was ok) because the vomiting was aweful, and ibuprophen for the headache. I'm still a little weak and shaky but better. I'm not completely sure if these are side effects or a 24hr bug that my room mates just got over. Both are equally possible, but I dont have a fever so I'm leaning toward side effects, but hoping it was just a bug. Guess I'll find out tomorrow and will up date later. "In-the-Desert" F 31 2 days
1/10/2010
 3  Depression dizziness, nausea, headache I started taking 150 mg a day of Bupropion (generic) as I was weaning off of Effexor. The Effexor worked but made me gain weight. I did notice that for the first two weeks, I felt angry. I stopped taking for a few days and the anger went away. I started the Burpropion again two days ago and I have no anger, but I started with the headache. I am hoping it will go away as I think it is helping otherwise. I feel more upbeat and able to cope. F 44 21 days
1/9/2010
 3  anxiety Anxiety!! racing heart. My dr. warned me of the increase in anxiety initially. Insomnia for first two nights. Slight ringing in my ears. More confrontational and irritable than normal. This is only day 4, but so far I am waiting for the side effects to subside. F 30 4 days
1/8/2010
 1  depression transient aphasia I only took Wellbutrin for one day due to the side effect- transient aphasia. I could not speak! Literally. I took the pill and for the next hour or two I couldn't say a word; I could think clearly but couldn't produce speech. It was like my brain got disconnected from my mouth. Scary!! F 27 1 days
1/2/2010
 2  Depression and anxiety I forgot already. Oh right -memory loss!!!! My memory loss is getting worse -not sure why but to eliminate (it juts took me about 5 seconds to figure out how to spell that word) -notice how I spell "just" as "juts" -its like a dyslexia of sorts - I misspell words all the time -often the same words over and over! Very odd. I have had weight loss -225 down to 205. Ringing in the ears, manic times of speaking, very poor memory, poor decision making or inability to decide on anything. I have lost my home, job and wife these past 4 years. Is it the pill - or?? Its odd that so many of us have the same symptoms though. I would not be surprised of class action suit any day now due to the memory loss side affect. Did I say poor memory already...? :-) I am getting off this stuff asap -slowly but surely. I want to see how I am "naked" without this drug and go from there - will memory come back, will tinitus stop and will I spell correctly again... this could be quit a ride. M 58 5 years
12/29/2009
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 3  Anxiety Increased energy, immediate weight loss, increased moodiness and short-temperedness I began taking this a couple of years ago, and took it for approx 1 year. Within days I noticed a marked increase in energy, and the weight (from 8+ years on Prozac), just melted off. I was ecstatic, and easily kept up the exercise as I had all those years of pushing myself. Unfortunately, though I didn't notice this as the cause, my mood had also changed considerably. I lost my temper very easily with my daughter, and our fighting and tiffs occurred almost daily. I couldn't understand it, blaming it on other circumstances during that time. I got off of Wellbutrin, and things went back to normal (normal moods, control of temper, also weight came right back on). I tried it again more recently (about 6 months ago), and could feel the moodiness creeping back by the second week, so got off of it right away. Was on 150mg both times. Would love to try again, if only for the energy and weight loss, but worry about un-justified moodiness. Will speak to my doctor about halving the dosage. F 43 1 years
12/27/2009

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