WELLBUTRIN SR Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.5 (997 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN SR  (BUPROPION HYDROCHLORIDE):  This medication is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2002-06-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN SR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN SRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  depression Messes up my body temperature so that it fluctuates wildly whenever I perform physical activity, like walking to work. It makes me sweat a lot. No sexual side effects like SSRI's but a tingling in my penis when I orgasm if I haven't had one in a while. I exercise a lot (run 12 miles a week, swim 5-6 miles a week) and without the exercise this medicines efficacy is greatly lessened. That being said it has saved me and allowed me to successfully recover from severe depression with almost no negative experiences due to the drug. M 31 6 years
4/13/2006
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 5  adhd little laid back than normal first few days drug is great, for the first time in about four years of soul searching bouncing from doc to doc, depression meds (lexapro, zoloft~these drugs are horrible side effects caused me to lose alot of friends personal and relationship type) then came adderall people who take adderall are sheer adrenaline junkies as is that drug pushes you in such a way (did help with focus though) after all this came wellbutrin SR and from the first day i have felt something i havent felt in years what a great feeling!!! 24 3 months
4/8/2006
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 2  stop smoking I started Wellbutrin SR to stop smoking. The second day I started having weird insomnia. I never had any sleep problems before. I would go to sleep at about 11PM and awaken 2-3 hours later, wide awake in the middle of the night and unable to go back to sleep for 4 hours. Then, I would be able get only 2 more hours of sleep before being up for the day. This is now 4 days straight without a decent night's sleep and I am starting to get annoyed not to mention exhausted. Yes, if the insomnia continues I will speak to my doctor. M 59 5 days
4/6/2006
 2  Smoking cessation, depression Suicidal thoughts, depression worsened This medication worsened the depression I was having and I would have bizarre suicidal thoughts. On the plus side it was helpful with the cravings while I was trying to quit smoking. F 26 3 weeks
4/4/2006
 5  depression I cried a couple of times which was novel, and felt more energetic. I don't need the provigil or amphetamines anymore, and I'm more clear headed. I took it years ago to quit smoking and it worked, now I've started again, so I hope it'll work a second time. F 36 18 days
4/1/2006
 1  depression and ADD Terrible anger and unusual rage. Jitteriness and insomnia. I had to stop taking this medication about 1.5 weeks after starting it becuase I was having episodes of uncontrollable anger and rage. I have two small children and this is unnacceptable. F 38 1.5 weeks
3/24/2006
 3  Depression, smoking cessation dry mouth, sweating, severe headache day 3 only (took excedrin and went away), memory loss, heart palpitations (mostly in night or early morning), loss of appetite initially now appetite back to normal While only on this drug for 5 days (up to 150mg 2x daily) I can't really comment on whether it's working or not since it will take more than 5 days to see the effects. The heart palpitations are worrying, but they do go away and I don't have a lot of them in a row. F 34 5 days
3/15/2006
 5  Depression + Anxiety/Panic Attacks Very few. Maybe increased libido (it this bad? ;-). Don't worry too much about side effects listed here and on the med's sheet; they happen to certain people some of the time and usually completely disappear within a few (1 or 2) weeks. Stick with your medication and talk to your doctor. This is a great medication! After trying about all SSRIs out there I was started on Prozac (up to 40mg daily) + Wellbutrin (up to 300mg daily) and it FINALLY happened within 2 months of starting this med! I was ALIVE again! Concentration was back, I was enjoying life again and most importantly for me I was not anxious about everything. After 3 years on leave from work I was back (and good at it) and 50 pounds lighter too due to decreased appetite. At one point we (my psy and I) increased my Wellbutrin to 450mg daily but it didn't do anything more so we lowered it back to 300mg daily. Wellbutrin clearly gave me a boost of energy; at one point I did a home project that lasted 6 weeks at 10 hours/day and I was full of energy (no, I'm not bipolar). I had never experienced soi much energy. Then the energy decreased to a more normal level. A note about Prozac in this context: when I was started on Prozac alone (10mg daily) my panic attacks ceased completely within a week. Maybe also M 45 700 days
3/12/2006
 5  Depression + Anxiety/Panic Attacks See my other post... (continued from first part) A note about Prozac in this context: when I was started on Prozac alone (10mg daily) my panic attacks ceased completely within a week. Maybe also the feeling of taking charge medically of my problem helped with the helplessness I was feeling and the anxiety it created. I don't know. After 6 months of going well on 40mg Prozac + 300mg Wellbutrin we (actually I) decided to decrease all medication *very progressively* and then stop completely. After 6 months of being OK (no depression, no anxiety) anxiety crept back again so I'm considering getting back on the meds now. STICK WITH YOUR TREATMENT and follow your health pro's advice. It does work! M 45 700 days
3/12/2006
 1  anxiety, depression Feeling like there is something in my brain which thinks for me - it was scary, dry mouth, gain weight, took a pill in the morning and at the end of the day felt scared, in the morning was irritable, anxious, tearful, depressed as never before until I took another pill. And they say that this drug is not addictive!!! I tried a lot of antidepressants but they never solved the problem. That is what helped me: neuroscience test (go to neuroscienceinc.com and get information about their test and products), book "Feeling Good" by David Burns (until you find all your silent assumptions (when you read this book, you will understand what I am talking about) which cause you depression you will never get out from it, this book will help to do this, cranial electrotherapy stimulation, deep breathing exercise – 3 times a day (do it when you are anxious and have panic attacks, also while doing it, imagine yourself as you wish you wanted to be), special diet for depression (really helps for mood swings), day light lamp, hot and cold shower, daily exercise, meditation, keeping schedule, acupuncture St. John’s Wort - 9 pills a day, Red clover - 6 pills a day, Omega 3, Calcium, B-complex. F 28 2 weeks
3/12/2006
 5  Depression seems minor. Perhaps some constipation, but maybe that's just from disrupted schedule. Minor tremor is gone now. On 300mg (2x150mg daily). WB is the only drug I take, seems like many others are dealing with interactions of this drug and others. I am slightly worried about 'floaters' in visual field of my left eye right now, but those may or may not have anything to do with WB. In the past (years ago) I've tried Zoloft (wore off after a few months), Effexor (yeach - and very hard to get off of), and also Depakote (not sure this did a darn thing other than make me gain weight). Of all these WB is definitely the best thing so far. At this point I'd say it is definitely helping my depression. I feel normal again. I have hey, ambition, again! My mood around my family is greatly improved. I am much less irritable and on-edge. The overwealming anger is gone. M 45 30 days
3/2/2006
 3  depression dizziness, mood swings, outbursts of anger, loss of appetite, homicidal thoughts, increased libido F 16 5 days
3/2/2006
 4  depression Side effects dry mouth for 2/3 weeks. Vivid dreams . Loss of appetite. Decreased appetitite for alcohol. Tired but maybe that because I am not sleeping as well as I thought I was due to intense dreams? I seem to be able to focus better on any single project. Feel spaced out but sinus' are not doing well the past 2 weeks so maybe it's that. I definitely feel different but in a very unfamiliar way. I am not sure if I can say my depression is gone but I am functioning, getting things done. F 43 26 days
2/27/2006
 5  depression Initially ringing in ears, general stimulation, mild tensing of muscles, mild increased libido, crying. All subsided quickly. Virtually free of side effects compared to previous nortriptyline, paxil, zoloft, serzone, remeron, effexor, lexapro. Improved mood and motivation. Now taking 450mg/day in combination with 600mg/day trazodone. M 44 1 years
2/26/2006
 4  severe depression weight loss (30 lbs), decreased appetite, decreased short term memory, increased libido, calmer, cry less, non-suicidal I am currently finishing up my PhD and was looking to change anti-depressant meds. OriginallyI was on Effexor as an undergrad- went off that by myself- BAD IDEA- I ended up punching someone from the mood swings. Then switched to prozac (20 mg daily) after being diagnosed with arthritis- caused me to lose my sex drive and almost my marriage. Switched to wellbutrin (100 mg twice daily)... I feel much better, LOVE the weight loss (went from 180 lbs to 150- I'm 5'7")- don't like the short term memory loss. Hard to find words sometimes, which makes talking about my research (I'm a chemist) very difficult. BUT the sex drive, calmness, and weight loss make me want to stick with it. OH and I tried to switch to wellbutrin XL from SR- bad reaction- ended up crying constantly and couldn't control emotions. quickly switched back- now AOK. F 26 4 months
2/26/2006
 4  smoking tinitus late at night - constipation (which means eating less) - not being able to peak like i did when exercising before the drug. early onset of menses. i stopped smoking months ago - but was all nicotined out with patches, gum, and lozenges. it's helped with the nicotine cravings but hasn't squashed them. hopefully - i don't get the rash. not as much sleep but still being cogent and coherent the next day. the 'euphoric' feelings of day 3-5 is long gone. F 42 15 days
2/14/2006
 2  depression, chronic fatigue, add increased anxiety, nervousness & minor shaking, slight jaw clenching, emotionally touchy Ability to get up in the morning is slightly increased, no depression lifting benefits yet. Had horrible, inexplicable crying fit recently. Anxiety has increased immensely. F 25 9 days
2/12/2006
 5  Major depression/GAD As many others I was jittery at first and really spacey. I would forget what I was saying/doing, affected short-term memory. Jaw-clenching. EXTREME PERSPIRATION especially face/head but now take glycorrelate-an anticholergenic and it totally works reduce the sweat dramatically. Reduced appetite. ALSO and this is the ONLY THING that has made me rethink Wellbutrin for a second and has really bothered me ..I KNOW YOU ARE NOT SUPPOSED TO DRINK on Wellbutrin (as most meds-seizure risks) but I still did and for MONTHS I would have these psychotic episodes with minimal alcohol where I would be really mean and say things that arent true and i dont mean. It was like an evil, alien me. I cant believe my friends put up with it for so long before telling me. Ive now stopped drinking completley and I feel its a small compromise for getting my life back but BE CAREFUL! I was on Effexor xl for 3 years for GAD but hadnt adressed my depression (for last 10 years maybe) and Effexor did nothing for my depression obviously. I now take 300mg Wellbutrin and 225mg Effexor Xl daily. I AM HAPPY!!! I cannot remember feeling happy, its like I was trapped inside a dark cloud and it has dissapeared! I ENJOY LIVING, I have MOTIVATION, which I didnt have for years! I go to the gym, watch what I eat and Ive lost 45lbs.On the whole Wellbutrin is absolutely amazing, im thinking of reducing from 300mg to 150mg to see how it goes. The side effects do reduce or dissapear but it takes time..please be patient and give it a real chance...however i know it cant help everyone and could be dangerous for some. But the minor side effects do go away. F 27 11 months
2/6/2006
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 5  Depression, hypomania, bulimia Sleeplessness to the point of exhaustion for the first week, than got a lot better, feeling slightly spaced out (but in a good way), shaky, hyperenergetic at times, increased libido Excellent, absolutely recommend it. I feel very peaceful, nothing bad gets to me anymore, I stopped crying and feeling miserable, I'm physically incapable of feeling miserable anymore. Stooped obsessing about food, was able to exercise and follow diet, lost about 20 pounds. It gave me a feeling of protection. F 18 45 days
2/5/2006
 5  Depression (loss of child) I am very sensitive to medication, so i started by splitting the pills and had no adverse side effects. The good things have been more energy, controlled eating, really happy and able to wake in the morning. For me Wellbutrin has been great. F 45 4 weeks
2/3/2006

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