WELLBUTRIN SR Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.5 (997 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

WELLBUTRIN SR  (BUPROPION HYDROCHLORIDE):  This medication is used to treat depression. It can improve your mood and feelings of well-being. It may work by restoring the balance of certain natural substances (dopamine, norepinephrine) in the brain.   FDA Approval Date: 2002-06-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN SR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRIN SRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Anxiety and Depression Dizziness, increased Anxiety, lack of concentration, Insominia, light headed, diarrhea and a feeling of “off balance.” Please email me if you have any comments. Started taking Wellbutrin (Generic) 5 weeks ago for anxiety and some depression and still has not "kicked-in." First my Doc said it will take "a few weeks" to kick in and then "3-4 weeks" and then "5-6 weeks." Okay, when is it? Worst thing is the Insominia and light headed feeling. Doc gave me a scrip for Trazodone to help me sleep and it had just the reverse effect. Now taking 50 mg Over the counter Sleep Aid and sometimes have to chase it with a low dose xanax just to get some sleep. I have made the decision to stop taking this tommorow and use the xanax for any "Break-thru" anxiety. M 46 5 weeks
2/1/2009
 4  depression/suicidal Started out at 300mg and had severe insomnia, dehydration, nervousness, weight loss (50 lbs since October '08), muscle loss, increased pulse. The weight loss was a great side effect, but now to the point where I need to stop. Have increased energy, but get tired quickly. When I first began taking it, had a stiff neck and teeth grinding, but that stopped after a few weeks. Feel nauseated in the morning, but could be from Ambien I take to sleep. Reduced my dose to 150mg - I take half in morning and half in the latter part of the afternoon. Tried to switch to Lexapro to combat the weight loss and it sent me into extreme fatigue and exhaustion. Switched back to Wellbutrin and energy came back within hrs. F 46 3 months
1/16/2009
 3   Been on this drug since 21 December when I realized I was suffering (another)bout of major depression. Started at 100mg for 3 days then up to 200mgs. I have now been on 300mgs for about 4 or 5 days. Ruminating thoughts are awful - I have faith this will kick in soon. If I didn't, I don't know if I could handle all the side effects such as increased anxiety and insomnia. I hope I can update soon and say "Wow, it finally kicked in!" But as of today, I am still an emotional mess. M 49 24 days
1/14/2009
 5  Depression Started at 100mg/day and worked up to 300mg/day (two 150mg tabs morning and night). The initial dose and each increase separated by weeks resulted in a "six expresso" caffine like event, couldn't sit still and lots of energy, which was OK. On going from 200 to 300 I had some tightness in the chest and a feeling that I couldn't catch my breath. These side effects went away after a couple of weeks at the higher dose. Increased sex drive. Persistant rining in the ears but not real loud. I've been on some other ADs and they had worse SEs. Nice to have sex drive. The ringing in the ears is the only persistant SE for me, and it is a willing trade for the regained desire to live and do things. If you are depressed and also lacking energy this may be a good choice. Some elevation of energy after 6 months of use but not much. I just feel much better. M 48 6 months
1/13/2009
 1  depression and energy loss for the first (and I hope only) time in my life I had persistant visual hallucinations. Having never had them I thought the "worms" I was seeing when my eyes were closed were real and then I thought I saw them moving on my face. It was very scary and I am going off it now. Not slowly Now. My GP thinks I am delusional and I have had a lot of funny looks because I told a few people about this when I thought it was real and I had some strange tropical illness. I don't know if others have had this problem, but it scared me a lot F 60 3 months
1/12/2009
 5  depression Dry mouth very hard to get started on this med. I had a lot of trouble sleeping. Increase in sex drive. I am driving my wife nuts. She keeps telling me that I am not 18 anymore. That is true but I feel like I am. M 55 2 months
1/10/2009
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 2   Mood swings, anger, bad thoughts, bad dreams. I have been on this stuff for 1 month now. Still having mood swings and bad bursts of anger. Anyone else have this problem and how long did it take to level off? Does it go away???? F 31 31 days
1/8/2009
 3  anxiety, depression,panic disorder dry mouth, constant thirst, stomach pain, nausea, dizziness, headache, very frequent urination, really wierd dreams, tiredness,diarrhea,weight loss, loss of appetite I was very tired the first day or two, now not as bad, the dizziness is still bad and I urinate all the time. The dreams are probably the worst side effect. I am having nightmares every night since I started wellbutrin SR. If not for the bad dreams then I think it would be more tolerable F 24 1 weeks
1/6/2009
 1  to augment Luvox SEIZURE Without ever having history of epilepsy. I had an EEG last month and DO NOT HAVE EPILEPSY.....so it was the Wellbutrin. DO NOT MIX WITH ALCOHOL, especially straight liquor. A lot of what I call "zaps", "zings", I would be having a conversation with somebody and all of the sudden I would feel this electric JOLT and it would be visibly noticeable to other people. My hands would seize up and my muscles in my eyes would twitch. Really scary. Be very careful with this medication....I was on the lowest possible dose EVERY OTHER DAY and I still experienced a grand-mal seizure. I did feel somewhat of an increase in mood and energy with this medication, but not worth it once I experienced all of those things. F 20 7 months
1/6/2009
 5  depression, anxiety Constipation, stiff neck first few days, teeth grinding Doc put me on Wellbutrin after my Celexa left me with no libido. I take 150 mg. twice a day, along with the Celexa, and I am so glad! I don't have to sleep 10 hours a day, I'm more focused, I feel good about myself and life, I'm playing with my kids more. I wish I would have started taking this sooner. No insomnia (I am prone to it). I still have down days but I can work my way through problems rather than shutting them out. I finally feel like a normal person. Constipation is not fun and I hope it subsides. F 36 3 weeks
1/5/2009
 5  depression sometimes i have a bad taste in my mouth, improved sex drive, i think i may have lost some weight but i cant really tell...i still have a few drinks on the weekend and it doesnt effect me, i just dont drink alot at once.. it made me happier and more aware. this drug really helped me, i have been depressed for many years. i thought it was just my personality to be like that until i hit a low and realized everything i have missed because of depression. I never believed in drugs, but i tried celexa (i hated it) and then 2 years later i tried again with wellbutrin and i have been on it ever since. happy with it, F 23 1 years
12/18/2008
 3  same as below Day 5-11 sad, depressed, angry Day 12 - seem to be a bit better today. No problems sleeping. A bit of nausea. Mood - a little less angry and sad. Hopefully this is the turn around time and this stuff will start working! I will give it another week. 150mg They really need a dosage column on this form. Its very important to know the dosage that goes with all these reviews. F 31 12 days
12/17/2008
 4  anxiety/moods muscle and bone pain, dry mouth, ringing in ears, dizzy, emotional wreck, zoombie Day 1 - 3 I was an emotional zoombie. Day 2 and 3 I couldnt sleep well. Bursts of anger. Day 4 - today, I am feeling stable enough to do the dishes! The last few days I was so depressed! I keep reading all the feedback saying to myself that it will take time to kick in. Today is the first day I feel somewhat normal. more energy, not as emotional... will keep you up to date. F 31 4 days
12/10/2008
 4  Depression, Muscle Spasms & Fatique At first, major anxiety, shakiness, memory loss, insomnia, major depression and suicidal thoughts. Dry mouth and a small amount of anxiety is present still. I am taking 150mg 2 X a day, it was hell going through the Wellbutrin at first because I had huge anxiety, lots of crying, lack of sleep etc... I aggressively walked the anxiety off when it came. (this helps in weight loss too) I have been on it for 2 months now and am finally leveling off, I definitely feel better than I did a couple of months ago, but a first I felt worse. On day 2 of taking Wellbutrin I had to admit myself into the hospital because I wanted to commit suicide. I was very depressed and could not stop crying for 3 weeks, the anxiety attached to all of this was huge and I had to take Ativan heavily for those first weeks. There is still some anxiety, but for the most part it is caused by my life situations. When my husband and I argue, the anxiety is triggered or when something goes wrong for me, again the anxiety is triggered. I also suffered with fatigue, that is now gone, but I still have muscle spasms. I now know that the spasms are triggered by stressful F 41 2 months
12/7/2008
 2  severe depression Initial Insomnia, Nausea, Loss of Appetite, Weight Loss, Irritability, Hives I took 150 mg for a week and then moved up to 300 mg. At first, I felt better for a day or two, except that I could not fall asleep at night (even with benzos). By day three, I experienced near constant nausea. I didn't even want to look at food, let alone eat a bite. Towards the end of the second week, I broke out in hives. From day 3 until the day I stopped taking WB, I felt constantly irritated and starting having hateful thoughts about the people I love most in the world. I dropped from 128 lbs to 115 lbs in 3 weeks. DO NOT TAKE IF YOU HAVE EVER HAD AN EATING DISORDER. F 19 3 weeks
12/1/2008
 4  Depression Headache when dosage increased, night sweats, more energy, better mood but effects faded after 6 months requiring dosage increase I think Wellbutrin SR is one of the best anti-depressants for me. It did not affect sex drive, ability to get erections or orgasm. Best anti-depressant if concerned about sexual side effects. M 1.5 years
11/25/2008
 5  depression/anxiety fatigue, dry mouth, weight gain then loss. At first I didn't notice any side effect except bad breath. Then I realized it was due to dry mouth and so I started eating sugar free candy all the time. The dry mouth went away after about 2 weeks. Well, I still have dry mouth but it isn't horrendous like it was! The first week or so I gained a whole lot of weight, but I think it was water weight. It dropped off very quickly beginning about the end of the second week and then the last two weeks I've been dropping weight really, really fast.. and let me tell you, I love food so I am not on any kind of a diet. What happens to me with the fatigue is that I take it in the morning and it is fine, but then I get really sleepy in the afternoon. I know most people get insomnia from it, but I don't have that problem. I think I had that problem the first two days that I took it but after that its been the opposite. F 35 1 months
11/13/2008
 3  Bipolar II Very vivid dreams, early morning waking, night sweats, very blurry vision and severe eyestrain when reading, somewhat constant low-grade headaches, decreased appetite, weight loss (12 lbs in 2 weeks.. has stabilized now), severe short term memory loss, some dizziness and fatigue in first two weeks If it weren't for the negative side effects, I'd be willing to call this a wonder drug. I've been on lexapro, lamictal, prozac, cymbalta, and lithium in the past, and this is the only drug that has been able to control my mood swings. Even so, I'm not sure yet if the side effects are worth it in the long term. I have nightmares about 3 times a week, night sweats, and the memory loss is debilitating. I used to have photographic memory, but now I can't even remember what I was doing an hour ago. I'm a junior in college and this drug has turned me from an A student into a C student because of the memory loss. Be warned with this drug, especially if you're sensitive to medication like I am. F 21 4 months
11/13/2008
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 3  depression and anxiety Weight gain, constipation, insomnia. Wellbutrin SR (150mg, twice daily) worked great for the first year and in combination with 10 mg. Pamelor in the evening. However, despite working out like crazy, I gained about 20 lbs. The cravings are impossible. I got off the Pamelor 6 months ago and the insomnia returned, but the weight stayed on. I then weaned of the Wellbutrin and my insomnia and constipation went away, AS DID MY SEX DRIVE, but the weight INCREASED FURTHER. Despite all this, my depression and anxiety did not return, but I am feeling irritable and annoyed. I think all ADs should be avoided unless somebody is suicidal or very severely depressed. Doctors prescribe these things much to quickly. If depression/anxiety are bad then go on the stuff for 6 months to a year, but combine with very, very serious physical conditioning, mental stimulation (i.e. something mentally challenging), and 'forced socializing'. After 6 months get off and just stick with physical conditioning. In the long run, this stuff screws M 43 18 months
11/13/2008
 1  Anxiety/Small panic attacks Restlessness, Tremors,Heart racing,Panic attacks. This is the first time I went to the doctor for my anxiety.I got prescribed Hupropion Sr 150 mg twice a day. I took this medicine for 4 days, and it was the worst thing ever..My heart wouldn't stop racing and it would hit me so hard and quick and go away I thought I was kinda dead, scared me to death. so I went to the doctor and had a full blown panic attack there. My blood pressure was 150/80 and it's normally around 117/65, and my heart rate was 120 bpm, and it's usually around 80. They did an EKG on me and said they believe I was just sensitive to the medicine, so now I got prescribed Hupropion hcl, 75mg. I hope this workss.. If you start feeling like I did, get to the doctor ASAP please. F 24 4 days
11/12/2008

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