FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Grade 1 small tumor, no lymph nodes Joint pain hip and knee, memory problems, hair thinning. Had five day internal radiation, no chemo. 6% chance of recurrence. On Femara for five months. Considering stopping. Radiologist says he wouldn't recommend taking Femara-- already had high blood pressure and high cholesterol, osteopoenia. Take Actonel, lisinopril, Arthrotec, Crestor. No family history of BC but mother passed away with heart attack. Anybody in the same situation? Would like to hear comments. F 66 5 months
12/18/2008
Email
 2  Breast cancer Very tired. Could sleep any time. Very bad back aches, knee pain, weight gain and unable to get up from a chair after sitting for a while. Don't want to exercise cause I hurt so much. I know I have to take it so I don't get breast cancer back, but it sure is unpleasant. F 66 8 months
5/1/2009
Email
 2  ductal carcinoma (mucinous, slow-gr Body aches others have mentioned, but not as bad as with the Arimidex. But stomach burning, bloat after several months and not immediately. Vaginal thinning of tissues, causing discharge and itch (gynocologist diag), itchy scalp recently, urinary frequency. Wonder if any other people developed the stomach burning, bloat and gain later on ? Also, skin on forehead and chin has become rough. F 66 1 years
9/9/2008
 2  new breast cancer after 22 yrs severe joint pain in hands,wrists & fingers. Broken bone in foot (1st broken bone ever), surgery on right hand for carpal tunnel (dr said from Femara), trigger finger on left hand. Hurt all over; Can hardly walk when get out of bed or stand after sitting for a while. Nausea, headaches, thinning of head hair, eyebrows and eyelashes. Hot flashes and night sweats; memory loss & confusion; depressed, decreasing self confidence. Recent bone density test showed osteopenia. Extreme tiredness & no energy. Didn't have any of this prior to beginning Femara. Life is miserable, no joy. Have considered stopping Femara; don't know if I can endure 3 more yrs. Side effects are getting worse with time. Was glad to find this websight and learn that I'm not alone in this misery. F 66 2 years
2.5 1X day
8/2/2010
Email
 1  stage 1 bc no nodes At my wits end!! I am still working 5 days a week at a very physically demanding job-on my feet for 8hrs with only a 30 min. break. Had NO physical problems before the bc diagnosis. Even felt great after rads. Femara is really messing with my quality of life- see onc next week to try arimidex. Who knows? If I could sleep and get rid of the aches and pains. Doing the one day at a time thing but sometimes it seems unbearable. Thinning hair, weight gain, etc. All would be tolerable if I just felt like I wasn't among the walking dead. It is actually beginning to affect my sense of humor. F 66 3 months
2.5 mg 1X day
7/19/2010
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 1  breast cancer four times felt like I was dying! every joint ached, bone pain, hair thinning, carpel tunnel syndrome, nausea, rash, sleepless nights I had already had breast cancer 3 times with surgery, radiation and chemo followed by 5 years tamoxifen (horrid) then put on Arimadex,only lasted 6 weeks...terrible skin rash....so put on Femera. Nightmare drug!! Took for 3 years and my quality of life became dreadful....felt 100 years old and my body acted acordingly! Eventually taken off femera as Dr decided i was simply allergic to it. two weeks later i was diagnosed with grade 3 breast cancer...forth BC diagnosis. more surgery, Chemo.... I now have serious hip problems, bursitis and wearing away of the cartilage, osteoarthritis, probably accelerated/caused by the aromatise inhibitors over the years Need hip replacement! I would NEVER take Femera again...not worth these lasting side effects! Am now on antiinflamiteries and pain killers to function!! F 66 3 years
30mg 1X day
3/10/2011
 1  Breast a cancer caused by HRT Hot flashes, insomnia, weight gain, arthritis in my hands & feet but worst of all vaginal bleeding. I just had a D&C &will have the results this week. If It comes back benign I'm going to be very upset. All this as a result of HRT& Femara. We're stupid to trust the drug companies, they want to keep us sick. We should turn to alternative medicine. F 66 4 years
2.5 1X day
8/12/2012
 1  breast cancer stage 1 I am off of femara since 2011. I am now suffering with vertebra problems in the lumbar spine at many levels (l1-s1) F 66 5 years
3/20/2013
 1  breast cancer in 2002 I was on Tamoxifin for 5 years, ending in May of 2007. My oncologist then put me on Femara. A couple of months ago, I noticed my hair was thinning but my hairdresser kept telling me it was my imagination. It has now been confirmed by my oncoloist and a rheumatologist that it is alopecia. Also, I was having terrible problems with my 'ring' finger on both hands, more so on my left hand. My family doctor said it was 'tringer finger'. I believed him and continued to suffer, as it got worse. By fluke, while my husband and I were in Florida in Janary, I met a women who had the same thing and she told me to check out the website for Femara side effects. I was totally shocked to read about all the problems women were having. I didn't sleep for three nights reading all the reports. When we returned to Toronto (Canada), I immediately contacted by oncologist and told her what was happening to me. She said that these side effects were quite common and took me off the drug for 1 month. We Can anyone suggest what to do about the thinning hair? My appearance and especially my hair have always been very important to me. I have ordered a wig and I guess will begin wearing it shortly. Also, very important, I have coloured my hair for many, many years and cannot find any information as to whether this will continue to affect my hair thinning out. Any thoughts? Please respond to my email. F 66 10 months
3/10/2008
Email
 1  Breast cancer Really bad hot flashes Headache Painful joints Insomnia F 66 2 weeks
Once a day
7/5/2014
 1  Preevent return of breast cancer I just learned today that the tinnitus I’ve had over the past several months that is getting worse and worse each day is a very real side effects of this drug Anyone else out there with a similar issue? This is the only medicine I take so I am positive that this is the drug that is causing my tinnitus F 66 10 months
10mg daily
8/1/2018
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 1  Breast cancer and my doctor put me Can’t stand for hardly any length of time . My feet hurt so bad I was in a wheel chair for 10 days. My sisters had to come in to feed me and my animals. I cryed so much I was sick. My knee and back went out worn knee brace and back brace. Still have back brace on. I can’t stand straight without it. Does anyone know how long these side effects last . mine seem to be getting worse than better. Been off the drug at least 4 months now. This Drug is dangerous. I’m in kidney failure not due to this drug . But cymbalta. I was on it 8 months went into kidney failure that soon stage 5 . Luckily I went off it and regained some of it back. I’m now a stage 3. Good luck to those having to take these drugs. Someone said thier doctor put them on it for pain it worked for my fibromyalgia. But got my kidneys.?????We are famed if we do and famed if we don’t. F 66 5 months
30 mg
6/4/2019
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 4  Breast cancer stage 1 Sweating, joint pain F 67 3 years
2.5 mg
12/27/2016
Email
 4  breat cancer stage 1 I have awful pain bottom of my feet - right shoulder - right knee -terrible pain in middle of my back - can barely walk - can barely get out of a chair - or go up and down the stairs - i hope i just have 1 more year to go on this pill - i feel like i am over 100 - Good Luck Everyone :-) F 67 4 years
2.50 1X day
1/5/2012
 4  Stage 1 bc I went on the drug at 66 and was already experiencing joint pain and stiffness, fatigue, and memory loss -- these have continued. Femara did seem to bring back the hot flushes of menopause, but not as intensely. I had some depression and my onco started me on Paxil. I continued this for six months and it helped. I'm not sure about brain fog, but I probably do have some of that -- it's harder to concentrate. I'm noticing that many people are experiencing pretty severe bone and joint problems, and I'm wondering if you are getting prophylactic treatment to protect your bones. When I started Femara, my oncologist also started me on Zometa infusions every six months and Calcium with vitamin D three times a day, both to counteract the effects of Femara on bones. You might want to check this out with your doctor(s). F 67 2 years
2.5 1X day
10/1/2011
Email
 3  Breast cancer, stage one I have been on Femara for 12 months. I experience some joint pain and have always had trouble sleeping so don't know if it is from Femara. My onc. told me that there would be bone loss, my primary care dr. did a bone scan so I was prepared. My main dislike is the weight gain and bloating. I quit smoking after 49 years so realize that part of the weight gain is due metabolic changes. I trust my onc with my life so will continue to take Femara for four more years. F 67 365 days
2.5 mg 1X day
10/13/2011
Email
 3  stage 1 breast cancer All of the side effects that others have described--Am now off of it--hope my life will return--The one thing no has talked about is having your hormones checked. I have had it done, paid by me, and found that they are truely suppressed. Therefore, the likelyhood of cancer returning was small. Now I'm off the femara, and I hope to lead a normal life. I, too, was grateful for the drug, however, at what price? I could have cried when I read of other women having the same experience that I have had with the side effects. I, too used every alternative healing I could do. I became a Reiki Master, and I believe with Reiki and alot of mental work, I survived the 5 years on this drug. I'm 67 years old. Joy to all women who are on this drug. Hopeful, someday no woman will have to take it as there will be a cure. F 67 5 years
2.5 mg 1X day
3/25/2010
 3  Breast Cancer Just read all the comments on this drug. I've been experiencing constant headaches the last few weeks and pain in my hips and legs. Really feels like a big throbbing toothache when it wakes me up at night (frequently) and is awful getting up in the a.m. or after sitting for 15-20 minutes. I took Tamoxifen for 5 years with no side effects at all. I'm wondering if this drug is really worth taking. F 67 5 months
8/25/2006
 3  Breast camcer Frequent clear vaginal discharge. I had the same experience with tamoxifen except when I was taking tamoxifen the discharge felt like it was burning. In addition I had two types of vaginits two weeks after I started tamoxifen. My doctor said the infections were probably due to change in the PH balance caused by tamoxifen. I am hoping that with Femara the discharge will diminish with time. The are the first two medicines that have caused a bad reaction in me. I am determined to continue taking Femara as long as the side effects are controllable. F 67 8 days
2/15/2006
 3  to prevent recurrence of cancer Low libido, vaginal dryness, mild hot flashes. I'm also having some other mild problems such as a sore jaw and knee pain, but I had pre-existing arthritis, so I don't know whether any of these problems were caused by Femara. I won't know whether Femara is preventing a recurrence of cancer until it hasn't recurred for many years. F 67 4 months
1/10/2009

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