FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Breast cancer recurrence Hot flashes and night sweats but bearable. So far no other side effects I'm taking letrozole and Ibrance. After only 6 weeks tumor is shrinking. Feeling fine except for the hot flashes. Please give these drugs a chance. Don't let all the bad reviews scare you. Everyone is different. F 48 5 weeks
2.5
7/6/2016
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 5  BC Initially no side effects, however I gained weight, which my doctor denies is caused by Femara, some thinning hair, but nothing too severe, a bit foggy The lump in my breast is gone! How good is that? After two years on it, ultrasound couldn't detect any abnormal tissue. F 48 3 years
2.5 1X day
10/5/2016
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 5  Breast Cancer Stage 2 no nodes ER+ Each morning, as I get out of bed, I feel like my feet are broken. What libido?? Have gained weight (could be the instant menopause from the Chemo) Don't multi-task/remember things (CRS). Otherwise feel great. It's a small price to pay to be cancer free (2.5 years)! Arimadex gave me trigger fingers. Couldn't open my hands without my ring fingers sticking. Much better since I am on Femara. F 48 1 years
11/5/2006
 4  stage II Breast Cancer Extreme bone pain in hips, hands, legs, feet most instense after rising from sitting, excessive sweating, weight gain (10#), memory difficulties, loss of libido i do not like the side effects of this medication and i am not sure i can tolerate it for 5 years. F 48 3 months
12/26/2006
 4  Stage I Breast Cancer Mostly joint and muscle pain, stiff neck. But not all the time, comes and goes, but neck pain seems to be every day. Do get hot flashes. I was diagnosed Nov 2007, had a lumpectomy and radiation and in March had a total hysterectomy. I have always had arthritis in my knees and carpal tunnel syndrome, so I am somewhat used to pain in these areas. The pain fortunately is not constant. Usually worse in the am, but I exercise in the morning, as well as in the evening. That definitely helps. I figure, if this is what I have to deal with to keep the cancer away, I will take it. I am only 48 and have a daughter (18) and a son (16), as well as a husband and other family members I want to be around for. I prayer every day for strength and courage for myself and others going through this. WE WILL SURVIVE!! F 48 6 months
10/20/2008
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 4  Stage 2B Breast Cancer Generally, I feel good except I just started with bladder pain which is very uncomfortable. Am on second course of antibiotics. My gynecologist says it is from low estrogen. Intercourse is unbearable with vaginal pain. Hot flashes are tolerable, although drenching. No joint pain or weight gain. Still have high energy F 48 4 days
1/6/2007
 4  Stage II Breast Cancer Bloating, weight gain, occasional muscle and joint pain. Beats the alternative! F 48 2 years
4/23/2009
 4  Breast cancer Bone thinning, hot flashes, joint pain, blurred vision, moodiness, stiffness F 48 2.5 years
9/2/2008
 3  Breast Cancer Low libido, foot pain, hot flashes, lost my eyebrows and my hair has thinned. Now I may be having uterine problems. I was not aware that this drug had so many side effects. Started on Tamoxifen, then I was switched to Femara. The hot flashes were really bad for a while but have subsided. I had no idea that foot pain was a side effect. The thinning hair is not nice. I have completely lost my eyebrows. I look really old without make-up. So far the cancer has not returned. I'm 6 years post diagnosis. F 48 3 years
9/12/2008
 3  Breast Cancer Very achy, especially hips and feet. Insomnia and massive sweats. Can go from boiling hot, to freezing cold within one minute. Headaches, tiredness, memory loss, breast pain, vaginal dryness, nil libido. Wake up feeling like my whole body is shaking. Diagnosed 2006 grade 3 breast cancer. Chemo and radiation treatment. Have been on Femara for 12 months, better for me than Tamoxifen or Aramason as I didn't function well on either of those. I am 48 years of age, but feel like I am about 80 some days. Light exercise seems to aleviate some of the aches. I have a feeling that my whole body is shaking when I wake up which is horrible. Have got another 3 years to go on this and will persist with it. Femara has worked out better for me and hopefully it is working. I wish I didn't have to take anything, cause I don't like the side effects, but hopefully its working. I would rather have the side effects from Femara, than go through chemo again. "We can do it", good luck to everyone. F 48 12 months
6/28/2009
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 3  Stage IIIB Breast Cancer survivor Every joint aches all the time. I can't walk down stairs as a result of the pain and I often feel like my knees will give out. Also my hips, ankles ache constantly. My hands, shoulders, elbows ache sporadically and I get stiffness in my whole body. I'm 48 and I often feel like I live in an 80 year old body. I was an athelete as a young woman and now I can't really run much. I also have bouts of anxiety that are followed by hotflashes. I go from hot to cold quickly as well. I've attributed these side effects to menopause (I had my ovaries removed) however it may be the medication. I would love to not have to take this anymore. I'm told that I'm doing great and I would rather deal with these side effects than go through chemo again. I just hope there is no permanent damage to my bones. I'm told that I only have to take this medication for 5 years. I'm in my second year. I hope the doctors are telling the truth. F 48 2 years
7/9/2009
 3  Breast Cancer Stiffness, joint pain, weight gain, difficulty standing after sitting in one position for a time (like at a movie theatre) Curious if the benefits outweigh the discomfort and constant reminder of breast cancer F 48 3 months
7/10/2008
 3  Breast Cancer Losing my fingernails (the skin on my hands looks like it has been severely burned), have developed immediate/severe suicidality/hot flashes/immediate onset of severe joint pain/muscle cramps/fatigue/naseau I coudn’t tolerate tamoxifen, so am now on this AI after chemo-induced menopause - I was on nothing for 1 month in between and felt like I did 2 years ago before cancer……all my joint pain disappeared, mood improved etc….within 6 days (two pills) all of my terrible side effects (the ones I had on tamoxifen) are back…not sure I’ll be able to stay on this…but if I don’t…I won’t last very long. F 48 17 days
2.5mg 3X W
10/30/2022
 3  Breast Cancer Survivor horrible hot flashes and weight gain F 48 3 years
1/18/2010
 3  Breast Cancer Been on Femara 8 months. My hand pain went away. Now I have bad back pain. Lower and mid-back. Does anyone else have this? Also, I can no longer run. My knees ache too much. I'm more concerned about the back pain??? F 48 8 months
11/13/2006
 3  Stage 2A Her2Neu+ Breast Cancer Absolutely MISERABLE!!! Terrible bone and ligament pain. Feel as if I am going to snap in two at any moment. I'm tired, bitchy(er) and I shuffle around like I'm 100! It's awful. I literally have been crying in pain, frustration & scared to death my quality of life was gone. But I FINALLY found relief! Read below... Desperate for relief, I would try almost anything. Yesterday at Costco I found NeoCell Super Collagen+C, Type 1&3. Holy Cow! And I mean bovine! I have only taken two pills and I feel as if I can do cartwheels! I've changed absolutely nothing...just added this supplement (and I'm very skeptical I might add). I've called everyone I know & decided to post on this forum because I finally have something to say that maybe we all haven't heard before. I have no idea of drug interactions or safety but I do know I can get up out of a sitting position without bracing myself for several minutes before walking. My knees, my feet, my arches and my fingers feel AMAZING. And to think I've only taken two so far! It's insane! Give this a try...you'll thank me! lol! :)) Please check w/ your onc first though because I am no medical professional and I'd hate for anyone to have more problems than they already do. FYI, I have slight stomach upset but it may be my coffee intake, either way it's nothing some Zegerid won't fix. YEAH!!!! I have my life back! Cheers and good health to all! :) F 48 1 years
2.5 1X day
8/21/2011
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 2  Stage III Metastic IBC severe stiffness and joint pain in ankles/feet. Weight gain. Hot flashes. 50,000 icu Vitamin D, hot spa tub for fee/ankles, requip for RLS, Effexor for hot flashes, STAY ACTIVE! 48 6 months
4/28/2008
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 2  Breast cancer Pain in joints, insomnia, blurred vision, feeling exhausted, numbness in hands, with extreme hand pain. Not able to sleep due to pain in hands, and not able to fully use my hands. Stopped taking Femara and started Tamoxifen several days ago. I am already feeling better. My hand pain and numbness have decreased a little each day, and my vision is less blurred. I tried but was not able to tolerate Femara. F 48 2 months
12/6/2008
 1  Breast Cancer Stage 1 Severe joint, muscle and bone pain. Tired. Feel like a 80 year old when I am 48. Hard to get up and move in the morning. My doctor took me off and told me that the side effects would go away. He wanted me to start Aromedix after a 30 day hiatus. The severe pain has not gone away. Has anyone experienced continuing pain after going off Femara. Has anyone had issues with Aromedix. I am at the point of not taking anything if it impacts my quality of life. F 48 7 months
1/21/2009
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 1  Stage 1, ductual carcinoma est. + Switched to Femara in May 2007 - by mid August I felt like I had been hit by a semi. My hands, arms, shoulders and legs ache. Recently I have been taking Davocet just to get to sleep at night. I have taken Tamoxifen 2 years and had very little problems. Had actually started to lose weight. Now I'm gaining it all back and don't have the energy or strength to exercise. I can't live like this! Will be almost a month before I can see my oncologist so I'm ditching the meds. My risk for recurrance is really low and I'm going to trust God for continued good health. F 48 6 months
11/5/2007
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