FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  To prevent recurrence Stiff feet waiking up in the morning, but smooth after walking for 5-10 minutes. . Cannot walk very far on streets unless I wear very soft soles, Cannot stand for very long. Insomnia.Some stifness in fingers. Knees hurt sometimes when walking up stairs. Body feels heavy. Sometimes hard to get out of the car and to raise up from a chair. Limbs feel weak. Memory loss - but that can come from insomnia. Less side effects this year than the three first years. I choose to continue with the medicine to hinder recurrence. Ithink changing diet has helped. a year ago I started to take 1g magnesium pr day with calsium, pluss a lot of cod roe oil, seal oil and flax seed oil,coconut oil through the day, and it has helped soften my limbs. I also eat a lot of fat fish and a lot of vegetables AND have stopped eating sugar and and wheat. Life is easier now than a year ago. F 60 4 years
2,5 1X day
6/17/2011
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 4  Hormonal induced breast cancer Very tired, arthritic type aches, swollen joints, if sitting for a while, when I get up it takes a few seconds to move properly. Low libido and very dry vargina, due to estrogen being drastically reduced in the body. Hair is very slow at growing and is very thin. F 60 365 days
1X day
9/8/2010
 4  breast cancer Maybe some fatigue. Muscle aches To tell you the truth, before I was to start Femara, I checked this web-site and it scared me half to death, the anxiety it caused me reading this web-site made me wonder how many women it scared off that really need this medication. I know several women who take this with little side effects. I would say mine certainly aren't that severe. F 60 15 months
30 mg 1X day
4/19/2010
 4  Stage 1 bi lateral breast cancer Bi Lateral lumpectomy July 2007. Radiation only and started Femara one month after radiation. Dry skin, joint pain, flu like feeling within two months of starting. It was also just three months after radiation. I don't believe I have any side effects today except dry skin, but the dry skin could be from the lack of estrogen from the hormones I took before the surgery. I started going for acupuncture 2 months after starting Femara as I was feeling bad all over and thought maybe a good massage would help but acupuncture was recommended. This person practices NAET which keeps the energy flowing through the body. I went weekly (two hours at a time) for six months and continue to go every two weeks. I am finally in an exercise routine again. I think the body is put through so much with surgery and treatment (as well as mental anguish) that it takes longer to recover then we realize. I will continue the acupuncture as long as I am on the drug. My oncologist said that one theory for the joint pain is that woman are more flexible then men because they have estrogen in the joints. The Femara blocks the estrogen and therefore causes the pain. Good luck to everyone. F 60 16 months
2.5 mg 1X day
4/15/2010
 4  prevent reoccurrence breast cancer hip,leg,shoulder weakness & joint pain,joint pain in thumb, mild hot flashes, hair thinning,vaginal dryness,weight gain,insomnia,no energy,get tired quickly, F 60 3 years
2.5mg 1X day
4/8/2010
 4  Breast Cancer Arthritis, hip pain, weight gain Has anybody else gained weight on Femara? I gain 30 pounds in the last 3 years taking Fermara. The first years was the worst, a lot of pain in hands, feet and could barely stand without pain. Now it has gotten better but I am not really sure why. I will be off of Femara (Letrolzol) in two 1 year 9 months. F 60 3 years
2.5 1X day
1/13/2013
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 4  breast cancer tiredness I have 144 tablets of Femara 2.5 mg. which I no longer can use. These are unopened bubble packets of 12 per packet. If you are interested in these, please email me. F 60 3 months
4/22/2007
Email
 3  Stage 3 Breast Cancer Severe feet/ankle pain especially getting out of bed first thing in the morning...bone/joint pain mostly in legs/feet...after sitting for a time, getting up and walking is painful...sometimes hand/finger pain...once I'm up and moving, it's better getting around...while stretching get severe cramping in feet/legs/back/arms, even mid-section...weight gain...irritable...impatient...some difficulty remembering words/names/making decisions...some hair loss...haven't had night sweats/hot flashes/nausea. Was on Tamoxifen for five years and just the last several months have been on Femara and have four years and some to go. If this drug keeps the big C from returning, I'll be grateful. F 60 8 months
12/4/2006
 3  breast cancer, 2 nodes, her+ daily like I'm getting the flu (muscle & joint aching - esp legs, arms & feet, verge of sore throat, fatigue, hair very slow returning and coming in very thin, vaginal dryness. It's early, but past 12 days no/little muscle & joint pain! Wanted to share, drinking liquid glucosamine from Walmart (Elations, 6 pack for $7) & walla! Much better than taking 8+ Ibuprofen/d. I did 1st day 1 bottle, then 1/2 bottle/day, mixing with cran-raspberry. also for vaginal dryness try KY LiquiBeads(a moisturizer), now to work on fatigue & thin hair - maybe life can be somewhat normal for the next 4 yrs on this stuff F 60 13 months
2.5 mg 1X day
10/3/2010
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 3  prevention The usual. Joint pain, foot pain, old person shuffle, stiffness, NO libido, vaginal atrophy, dry skin, fatigue, weight gain, rising blood pressure, bone loss Just told yesterday time to stop due to bone loss. I cross my fingers that 5 years of putting up with the side effects was worth it. F 60 5 years
2.5 1X day
1/13/2012
 3  Stage II breast cancer aching muscles, tired, hair loss, vaginal dryness, memory loss. Have no idea whether Femara is working or not to reduce risk of reoccurrence. Some of these symptoms were present during chemotherapy but energy level and mental state was improved at the end of radiation (before femara); I felt like myself again. But after Femara the muscle pain is new and makes moving slow and laborious; memory loss seems more pronounced again. Hair started growing back during radiation, but now seems to have stopped. Still have neuropathy (pain/numbness of fingertips and feet) but don't know if that's from chemo or Femara. F 60 3 months
1/17/2010
 3  Breast cancer post therapy I was diagnosed stage I breast cancer slightly estrogen and progesterone positive and HER 2 positive. Had 4 chemo treatments and 6 weeks of daily radiation. Then a year of Hercepton. Was started on Letrozole 4 years 9 months ago. Only side effects I started with was weight gain. Then about 3 years into therapy my knees became a problem and I had bilateral knee replacement in early 2016. Then the low back pain started. It is so bad I have had 3 epidural injections none of which gave me any relief. I have been to orthopedic doctors, spine specialists, neurologist, and pain management. None have helped. I also had a trigger thumb earlier this year but that was injected and now has improved. I just started to notice recently my hair has begun to fall out in amounts that are not normal. I can't even walk into a store from my car without having to give my back a rest. It burns with pain. None of these doctors ever mentioned the letrozole could be causing my problems. Are they oblivious. I started researching and came across a lot of blogs talking about my same symptoms. I had 3 months left to finish my 5 year stink with this drug but I could not take it anymore. I decided to stop the meds and see if I improve. Lord I hope so. I have not told my oncologist yet. She will talk me into staying on it. She told me in March I need to get a hysterectomy so they can put me on Tamoxifin for 5 more years. New treatment is 10 yrs. let me know how long before I notice any change F 60 5 years
2.5 mg
6/26/2017
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 3  Breast Cancer / Mastectomy Started with Arimidex. Have pain mostly in hands and feet. Struggling with weight gain. Carpal Tunnel symptoms in hands. Most of the time I am cold and then the Hot Flashes with profuse sweating. I used to be very active and enjoyed excersise. It's a chore now. Don't feel depressed which I'm thankful for. Noticed a definite lifting of spirit after changing from Arimidex. I never had Chemo or radiation to go through. Hate feeling in hands and feet. Supposed to be on this 5 years. UGH!!!! F 60 7 months
9/16/2008
 3  Stage 1 breast cancer Bone aches (feet, knees). "Chemo brain" and difficulty finding the right word. Last few weeks muscle aches here-and-there in abdomen and shoulder (feels like a boil!). Hot flashes, vaginal dryness and no interest in sex. After reading what other people endure, I feel fortunate. WAY better than a recurrence of cancer. 3 4 or 5? I can't say if the femara is working, or I'm just lucky. I'm doing yoga and crossword puzzles to compensate for aches and mind-fog. F 60 9 months
9/14/2008
 3  stage 1 breast cancer joint pain, tiredness; rating seems irrelevant, how can you tell if it is working against the cancer or not; only have side effects for now, so gotta assume that it is working. just hope it is working; this is a wonderful site; thought I was imagining the joint pains I was feeling; knowing that I should be going off meds in about a year is really an upper. I will stick it out till then; hate to quit, have recurrence, and think "I should have..." F 60 4 years
6/14/2009
 3  breast cancer Hot flashes, bone and joint pain, insomnia, depression, weight gain I have been taking Femara for 5 months. I started right after radiation was finished. Doing pretty well the first few weeks. I was walking a lot and climbing 3 flights of stairs several times a day at work. I thought now that the chemo and radiation were over I could get back in shape (can you believe I gained 20 lbs during treatment? Who does that?) Suddenly one day, my knees felt like they were breaking in half. The foot pain came after that. I walk like an old woman first thing in the morning and after sitting for a bit. I feel like my neck needs to be stretched. The worst is my fingers. I now have 5 fingers that pop out of joint continually. It is very painful. I was not sleeping well and now it is almost impossible because of my fingers. After 6 hours I can hardly type. My oncol. says this will all go away and everything returns to normal, but I don't know how these crooked hands can be normal again. I have lymphedema and have done that therapy and pt for shoulder and arm pain. I too am grateful to be alive and will keep it up, but it is difficult. I cried when I read all these comments. May God bless all of us. This is really hard. F 60 5 months
9/8/2009
 3  breast cancer/double mastectomy arthritic pain in shoulders, neck, back hands, wrists and feet. extreme vaginal dryness, loss of libido. fatigue. insomnia. so many have mentioned foot pain. the only shoes i can wear are called 'crocs'. if i try to go barefoot, i cannot walk more that four steps without flinching. these shoes are a godsend. however, they don't look good with dresses!!! but, at this point, who cares? i take one vicodin in the morning as well as meloxicam, an anti-inflammatory med.; folic acid with b vitamins rid the migraines. i take one tylenol-3 at night for foot pain, as well as one extra strength tylenol, plus 100mg trazadone and 1/2 benedryl to help me sleep. on 12/28/10 i plan to take my last femara. i fervently hope that these side effects will go away on that day. if not, will the doctors tell me that it's all a result of post menopause? will this continue till i die? i don't know if this medicine is working or not. perhaps the fact that i haven't had a recurrance means it is working. F 60 2 years
4/10/2008
 2  Follow-up to stage 3 breast cancer Extreme joint and muscle pain. Large weight gain, difficulty in losing weight.Felt like an 85 year old, having to peel myself out of a chair in stages, I lost my "bounce" or zest.With chemo I also lost several toenails and experienced numbness in hands and feet. Most of numbness is gone, small amount is probably permanent but bearable. My hair came back much thinner than before. I am going to a hairdresser who uses an ecocolor product which is not caustic and is safer for us. I have been on Femara for one year so far,and I was ready to talk to my oncologist about stopping it until I found a solution! Many women are not satisfied with living with the body they seem to be stuck with. Quality of life needs to be considered, too.We want more from these so-called wonder drugs! I have solved the extreme pain for me and I hope it works for you! I take 1 extra strength Aleve in the morning with a glucosamine tablet (not even the arthritis strength though I have arthritis) and it works! The anti-inflamation component is the key, since Femara obviously inflames joints and muscles. I have a personal trainer who has researched the weight side effects with me and my age (60) and says that weight loss methods (Weight Watchers)that worked for women over 50 in the past, will not work with us now. I eat "clean" 6 days, have forbidden food (starches and sodium)1 day. I hope it works for me this time.I am exercising 5 days a week,an exercise class in the pool with styrofoam weights two of those days. Water excercise is very soothing on joints and muscles, and can be as strenuous as you want it to be.Drug manufacturers and doctors need to know that quality of life is as important to many of us as life itself. Also, on my insurance that I am locked into because of F 60 1 years
3/7/2008
Email
 2  breast cancer, Her-2+, ER+ Been taking Femara for 2 months. Have bad joint pain in knees, feet (particularly toes), elbows, and hands. Knees really hurt. My body aches all over; My emotions are all over the place too. Cry more. More feelings of sadness. I'm also on Herceptin (since October), so have wondered which med is doing this. These side effects have come on gradually, but if they get worse, I may go off it. Will talk to my oncologist. My rate for recurrence was off the charts (Her-2 3+) so had bilateral mastectomy, chemo, and now Herceptin and Femara. F 60 2 months
1/5/2009
Email
 2  BC stage 3, 8 nodes +, hormone + pain in every joint, cramps in muscles, knees hardly work now, foggy brain, dry skin, dry eyes, vaginal dryness, thin hair, some anxiety, some depression, exercise is difficult when it is so hard to move very worried about side-effects easing once drug is stopped, hope I can stand this for one more year? F 60 4 years
9/11/2008

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