FEMARA Reviews (LETROZOLE)

Average Rating: 2.5 (1087 Ratings)

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 HORMONAL BIOLOGICAL RESPONSE MODIFIERS AROMATASE INHIBITORS

 Type: Rx Drug

  

FEMARA  (LETROZOLE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Letrozole is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Letrozole decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers.   FDA Approval Date: 1997-07-25 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR FEMARACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Lumpectomy and Lymph nodes removed Joint pain, fatigue, sadness, memory problems, hot flashes, Miserable Wish I didn't have to take it- scared not to- F 64 4 years
2.5 1X day
6/21/2010
 2  post second occurance of breast can Hair thinning, hot flashes, slow hair growth, joint pain F 64 17 months
2.5mg 1X day
11/18/2010
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 2  Breast cancer grade 2 mastectomy Vaginal atrophy,joint stiffness, extreme fatigue and tiredness , hot flushes, insomnia Vaginal atrophy almost immediately. Over the last 12 months insomnia ,lethargy,and extreme tiredness. I have lost me! Will continue with the drug at present but it seems to me that the cure is worse than the disease. Feeling quite depressed. Rads no Chemo. F 64 12 months
2.50 1X day
8/6/2014
 2  Estrogen & HER2 Postive BC Constipation, insomnia, joint pain in hips, weight gain, bottom of feet sore. Recently 2 joint flare ups which are very painful - caused by Femara? Who knows! I would like to stop Femara. My tumor was small, stage 1 and no lymphs involved. Had left breast masectomy, Herceptin infusions for a year and have been on Femara since 11-20-08. Oncologist not happy with what I'm thinking. Now with the recent knee and wrist flare-ups which put that part of my body out of commission I'm wondering if Femara is the cause. Flare-ups last around 24 hours so not as bad as some of you. F 64 1 years
11/26/2009
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 2  breast cancer Had lots of side effects, including joint/muscle pain, depression, anxiety, and lots of hot flashes Trying to get on another drug, probably another AI, and am not so confident I will ahve a different result. F 64 90 days
11/30/2008
 2  Breast cancer/chemo/radiation/Femar The side effects are muscle/joint pain, tiredness, depression,female organ problems (overies, vaginal discharge, sore breasts). I am concerned about having to be on this drug for five years....just have completed 3 months and the side effects are taking their toll. F 64 90 days
11/22/2008
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 1  breast cancer I had been on Tamoxofin for 5 years. I then took Evista for about 1 1/2 years when my doctor put me on Femara because it is more effective. I was fine in the beginning. After two years or so, I started having pain in my right hip and down my leg where it was uncomfortable to walk. I also developed neuropothy in both feet. I did not understand what the problem was. I went to multiple doctors, and no one could figure out what was going on. A year later I was in so much pain that I had trouble sleeping and could barely walk at all. Long story short, it was the Femara. I have been off of it for a year. After several months, I was not feeling that much better, so ended up going to an accupuncturist only becaus I was desperate! The next day my pain was gone which absolutely amazes me. I still have the neuropathy, but I can deal with that. I started last january having a monthly injection of Faslodex which so far has caused me no problems. I almost forgot to respond to this web 3 1/2 years F 64 3 years
7/17/2008
 1  Breast Cancer I had a mastectomy in 2006, I did not have chemo or radiotherapy. My doctor put me on Arimidex, I had so many side effects he changed me to Femara in late 2007. I already had arthritis and a little bit of osteoporosis, but since being on Femara my quality of life has gone down hill. My memory is bad, I am tired all the time, my osteoporosis is worse so I am on Aldendronate. I now have to use a walking stick some of the time. I get very depressed and teary my health is going down faster than what it would have been. I want to come off the Femara but am a bit scared of doing so. Am seeing my doctor soon and see what he says. Cant really gone on like this forever. When I went on this drug I had some of the side effects but over the past couple of years the side effects have increased. Since going on it I have now been diagnosed with Factor V Leiden which is a clotting disorder, and read that clots are mentioned in the femara right up. Dont know what I am going to do yet. F 64 2 years
1/9/2010
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 1  BC stage 1 Depression. Headaches, bone pain, vaginal dryness, trigger finger, bloating, weight gain around middle, fatigue, insomnia, nausea. I have lost my zest for doing anything because I am too tired and brain stays foggy! Going back to alternative estrogen blockers! This is the second time I've tried this med. I had hoped to react better. Feel great when not on it. Too many great natural treatments out there to continue suffering like this Get Christine Horner's book, Waking the Warrior Goddess. Christiane Northrup's book on menopause and Dr John Lees book What your Doctor won't Tell you About Progesterone. Awful drug F 64 6 months
11/28/2014
 1  Breast cancer Initially hot flashes joint pain, muscle pain , depression, and made me feel like I was 90 and life was over I would highly recommend steering clear of this drug. It was made clear to me from the Onco after many complaints that this drug gives you a whole 2-7% advantage against cancer returning. Definitely not worth the awful downsides! I've quit it after a year and feel slightly better after being off it for 6 months now, but still have joint pain muscle pain, difficulty getting going after sitting awhile. Terrible! F 64 1 years
1 daily
12/25/2019
Email
 1  To prevent breast cancer returning Started with Arimadex 14 months ago and was switched to Femara 6 weeks ago. Had severe side pain on the arimadex. My side pain is gone however I am having pain in my neck, knee and calve. I cannot go to the gym anymore and my quality of life has been compromised. I’ve had it. There are so many side effects that if cancer doesn’t kill me, a side effect will. Having my first grandchild this Dec and plan on being an active grandparent. This won’t be possible if I continue deteriorating. I choose quality of life. Am going to try a homeopath to see if there is another way to reduce my estrogen. F 64 12 days
2.5 mg
8/16/2018
 1  Stage 2 breast cancer, her2positive On the sixth day of taking this poison, the pain in my foot and hip became so intense I was unable to walk. On day 7, I had a stroke affecting my right arm and hand. Was hospitalized. Immediately quit taking the drug. Almost two months have passed and still cannot use my right hand. Physical therapy twice a week, can now wiggle my thumb a little. This has pretty much destroyed my art career. Was not advised by my doctor that this drug can cause strokes and heart attacks. I have a family history of heart disease and stroke, which i stated in my patient info. Should have been on blood thinner, like baby aspirin. At least the horrible pain in my hip and foot has subsided after two months. I can walk now. F 64 7 days
2.5 mg 1X day
12/25/2016
 1  stage 2 breast cancer severe bone pain in hands and shoulders, no strength. difficult to walk when first awake in morning. aching has brought tears the past few days. am extremely active, but hurt so much now that movement is impossible. considering throwing the stuff away!!!!! have call into onocologist. is this worth it??? had 2 surgeries and radiation last winter. ONCO DX test provided info that no chemo necessary.on pain scale, I am at a 10 today!!!! I am reading these posts and realize that I am not alone in this. I thought I was getting old!!!!! want to be able to open my bottle of water with my hands again. I am thinking if the cancer doesn't get ya, the meds will (one way or the other!!!!) F 64 120 days
1X day
8/11/2010
Email
 1  post breast cancer chemo/radiation My comment regarding this drug is posted in April of 2010. At that time I was going to tell my Oncologist that I was going to discontinue taking Femara as "quality of life" was as important, if not more so, than living with extreme pain this drug was giving me that virtually gave me no productive life. Since that time, after discontinuing Femara, my joint pain has gradually disappeared, though I still have hip pain that radiates into my legs which is a combination of degenerative changes and I firmly believe, as a result of this medication. Prior to taking Femara and even after chemo and radiation, I did not experience pain until Femara came into my life. So far, by the Grace of God, I am still "cancer free" and feeling like I have a life once more. I still read comments about this drug and my heart goes out to those of you who are experiencing the debilitating effects of this drug. F 64 3 months
20 mg. 1X day
6/5/2012
 1  stage 2 breast cancer I quite taking Femara about 2 weeks ago and when I go back to see my ocologist I am going to tell him that I have quit because I am tired of hurting and feeling bad. I am looking into estrogen blockers from health food stores and will contimplate taking these instead. I don't want to take one drug to conteract another drug. Still no guarantees even if I continuted to take Femara so why hurt? F 64
2.5 1X day
3/14/2011
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Patient History
 1  BC Stage 1 This is follow-Up to 1-24-2012 post. Although better, still having back pain/knee pain every day. I know this was Femara that caused.Never a problem prior to taking Femara. Only took for 90 days before ditching this poison, but now 8 months later and still having pain problems. Stay away from this! So far my BC check-ups are good. But will I ever recover from this horrible drug??? F 64 90 days
1X day
8/16/2012
Email
 1  Breast cancer Terrible hot flushes, joint pain, sleeplessness, crying, ageing, tiredness. Lost use of ring finger on right hand and rest of fingers and thumbs affected and very painful. Mornings are the worst. Was meant to be on it for five years only lasted five months. F 64 5 months
2.5 1X day
10/13/2012
Email
 1  Estrogen Positive Breast Cancer Three weeks into taking the drug I developed the most severe depression, anxiety and mood swings. My oncologist put me on an antidepressant. I suffered from nausea every day. Towards the end of the 4th month, I became short of breath and felt like I was suffocating. After extensive tests, it was determined that I had lost 1/3 heart function. I suffered from the uncommon side effects. Never did have bone and joint pain, but I think the loss of heart function and depression were worse. I have gone off the drug, I will take my chances... F 64 4 months
1X day
10/7/2013
 5  stage 4 recurrence of ER+/PR+ BC Multiple tumors shrank & disappeared after 6 months of drug use. Side effects included joint pain & sleeplessness, which improved after taking glucosamine/chondroitin. 2 years in got bad trigger thumbs, which resolved without intervention in 3 months. Sleeplessness has gone away; now just need more sleep (9-10 hours). After 3 1/2 years, tumors have not recurred. I consider the price paid well worth it. F 65 3.5 years
2.5 mg 1X day
4/4/2013
Email
 4  stage II breast cancer 4lymph nodes extreme foot and hip pain and vaginal and skin dryness occasional headaches After 6 months on femara began taking MSM and "Move Free" has helped tremendously can now walk 1 hour at amoderate pace still have dryness and feel cannot use an estrogen product as breast cancer was 100% estrogen positive this has interfered with intercourse Was on tamoxifen for 5 yrs after 5 rounds of chemo and mastecomy will continue femara feel that I am doing something positive F 65 3 days
7/31/2007
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