SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Bi Polar / Sleep Minor weight gain, This medication has really worked well, it allows me to sleep through the night and keep my mind from racing allowing me to better focus on what I am doing. I would highly recommend that you at least try this medication. M 43 2 years
400mg 1X day
2/14/2010
 5  Bi-Polar Weight gain. Have been on Seroquel for over one year. Gained 45lbs. But with diet and excercise I have lost 35lbs. and still losing. Life saver for me. This med is the best I have taken. I took Effexor XR 150mg for three years but my Doctor at the time misdiagnosed me. My new Doctor has me on Trileptal 300mg, Lamictal 100mg, Seroquel 600mg and Klonopin 1mg. I have never felt better. M 43 1 years
11/27/2006
Email
 5  severe insomnia side effects were positive. best sleep i've had in years-- including good dreams. i have not gained any weight as my appetite has remained unchanged. makes ambien look like a placebo F 43 1 years
1/15/2006
 4  Night time anxiety & hallucinations So far there has been tiredness on waking, and sleepiness during the day. My hallucinations are gone at night (which is great) but I still actively dream, and wake feeling very tired and stiff. I have dry mouth and some constipation as well. F 43 3 months
100mg 1X day
1/10/2012
Email
 4  bi-polar 2, insomnia extremely sedating (the reason I use it), hangover with significant irritability attached, carb cravings I have used seroquel very infrequently over the last 6 years until recently. I normally would only use it when I would start ramping up manic-wise which always results from sleep deprivation (more than 2 nights consecutively getting less than 2-4 hours each night) and would only require 25-50 mg to knock me out for a solid 8+ hours. I didn't like the side-effects so I'd rarely take it more than one night. Recently I've been battling depression insomnia, so I started taking very small amounts (10-15 mg) which seems to help me get a solid 5-8 hours so I'm keeping that up. I was previously taking temazepam but was concerned about addiction/rebound. Does anyone have any comments? (please email) ... specifically - a poster on here said that smaller amounts are known to cause greater sedative effects so to get less sedation but better positive effect take larger doses??? Sounds backwards to me and I could find no credible source information to support that statement. M 43 6 years
12/1/2008
 4  Bi polar Sleepiness on 100mg at night. The sleepiness continue through the day. really hard to get up. After reading all of these ratings it makes me nervous. I really don't want to gain weight, and don't like the idea of it being something i can get addicted to. I've only been on it a little while so will see. I won't be able to handle the sleepiness long term. F 43 30 days
2/27/2005
 4  Bipolar Brain fog, weight gain, lethargy, joint stiffness and aching muscles, sugar cravings. I was prescribed a generic version for insomnia, it was very effective at calming my racing thoughts and inducing sleep. I tried to manage my mania with just 50mg of quetiapine, which worked to a certain extent. However my depression deepened to the point of suicidal thoughts, at which point I started taking Lithium. Over the past 3 months I have reduced my quetiapine to 25mg 1 hour before going to bed. I noticed that my muscles were aching more and I was experiencing acute stiffness in my joints. I have not taken it for 2 nights now and the muscle pain and joint stiffness has disappeared. I have managed to sleep OK and will only continue use if needed as a sleep aid. M 43 9 months
75MG
8/19/2019
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 4  Mood Swings For years I've taken the genetic brand at 200mg. For the past two years I was losing control of my mood swings. I'd dwell on things for a long time. I'd make myself sick with anxiety. All this became my normal. I'd watch others and think how can they just enjoy the moment without freaking out about tomorrow? My new doctor told me that 200mg was like a maintenance dosage for me so she upped it 400mg XR name brand. I now feel numb almost to things. It's like I don't care much anymore about anything. It's kind of scary to sit at work, driving in my car, being at a restaurant or even at home and not stressing out about anything anymore. I mean this may be normal to a normal person but to me it's all new. I asked my doctor if this what was supposed to happen. She said that the higher dosage extended release and Adderal is allowing my mind to function without being manic. She asked if I still have empathy. Not a question I've ever been asked but I really don't know. I mean if something happens around me and catches me off guard emotionally I'll react but not to the extreme and it'll subside very quickly. It's just concerning to me because I've never been this calm about anything and now everything doesn't bother me...much. Not sure if I'm asking a question or just putting it out there to see maybe others have the same confusing thoughts. Does this make you lose empathy? M 43 1 months
400mg XR
11/15/2016
Email
 3  Bipolar ll, PTSD Side effects accumulated as dose was increased. Recent rapid weight gain, dizziness. At first too sleepy, now not sleeping and irritable, could be losing battle with my disorder. Take entire dose at night because of sedation, when I am up anyway I just must be careful rising and walking around. Very vivid dreams, but not nightmares I was having. Terrible heartburn. Constipation counteracts my lithium runs, so happy ending there. THIRSTY. My mood seemed depressed at first- I was sleeping 12 hours or more on 25 mg. I quickly adjusted and soon needed 100 to sleep at all. More cycling raised the dose again, and I was dropping dosage of Topomax due to side effects so Seroquel was counterbalancing. Just up for 2 days, time to call the doc but I am not sure what next...also gained 5 pounds in 2 days- essentially without eating. This is an issue for me. F 43 7 months
2/22/2005
 3  depression,bioplor,anixety, panic I have no side effects at all my body has a high tolerance to prescription drugs. F 43 4 years
100 mg 1X day
8/10/2010
 3  Self-destructive behaviors/insomnia Depression improved dramatically over time, insomnia disappeared, no major side effects but now after so many years somewhat concerned about long term dangers of Seroquel 300mg/Effexor XR 150mg. I plan to taper meds as soon as I move out on my own. I know still living at home under the tremendous stress/anxiety I am under, it is not a good time yet to get off meds which help at the moment cope better with my living situation. My father/brother alcoholic and my my Depressed/Borderline Blind elderly mother who depends on me for everything. Whatever you decide please consult with your doctor first. God bless us all and free us once and for all from Mental Illness. Awi :) F 43 6 years
300mg 1X day
3/20/2011
 2  Depression, Bi Polar, Anxiety, ADHD It only took 2 days to know that i would not be taking this med any longer. It made me very tired all of the time, like a zombie. No way i could work taking this drug! As with any drug, people respond diffently, so there is only one way to find out if this is the drug for you. M 43 2 days
7/21/2006
Email
 2  Mood Stabilizer Weight gain! Excessive sleeping. No energy. Unable to think or function. Blurred vision. Only thing this is good for is to get some sleep. Other than that the side effects are NOT worth taking this. I stopped taking it last night and NEVER want to take this again. I would rather stay awake all night long. F 43 3 months
4/26/2007
 2  mood disorder I had what first started as occasional and then became daily occurances of hypotension. My BP would drop from 120/80 to less than 80/60 in a heartbeat. It would take me 3 to 4 hours for my body and the blood pressure to recover. My Dr. has taken me off of it. Not very good for the 200 mg 2 X daily, combined with 2 other seizure meds, UGH! I was very zombie like, although I certainly had an even mood. We were never quite sure this is what I needed. I feel better off of this. F 43 9 months
6/22/2005
 2  PTSD DAILY MIGRAINES, groggy in morning, short-term memory loss (forgetting what I was just about to say), loss of multi-tasking abilities, GI issues, gassiness, fast weight gain, craving for sweets upon waking, zoned out feeling. Sadder, but that's not necessarily a bad thing, as I had a lot to feel sad about. Seroquel did help me in three ways: it stopped me from dissociating and going into flashbacks of abuse, controlled my nervous hives, and helped me sleep. Unfortunately, I couldn't bear the side effects, particularly the daily migraines. I was losing most my day to pain and grogginess and did not feel at all productive. My side effects were at a mere 12.5 mg. That's not a typo; I had to cut the smallest dose (25 mg) in half because I'm REALLY sensitive to medications. I've been off it a week now and am dizzy every day, with increased tinnitus and strange ear pressure changes (hope that is temporary!) but at least I have fewer migraines. F 43 2 months
12/27/2008
 2  Anxity,seeing things,hearing things Constipation,crushing chest pains,vivid dreams,zombie like could not function,slow alertness,nothing really matter. I slowly was introduced to 300 mg but the night I took it I thought i was stroking out chest crushing pain my heart felt like it was about to burst right out of my chest. Next night i broke it in half and still was like a zombie.This is an awful medication to be on. I was prescribed this because I had real high anxiety and thoughts of crazy things and seeing things that were not there my doctor said that was because of the prozac. The only thing I did like was the crazy dreams very vivid almost real like. F 43 8 days
2/18/2008
 2  schizoaffective disorder surprised to learn on this site and from experience that it is addictive - like i didn't take my usual 100 mg last night and i couldn't sleep at all, although the body and mind was needing to - but the more i take it, the less sedative effect it has - meaning, it takes longer for it to knock me out, and i don't sleep for the 12-14 hours anymore that it got me doing when i first started taking it - the psychiatrist told me that it was not at all addictive, no dependency - but it hasn't panned out that way, and it looks from this site like that's the general experience - in any case, sleeping wasn't a focus of my issues before at all, it's only become so with taking this drug have been taking 100 mg of seroquel at night with 80 mg of lovan/fluoxetine in the morning, for almost 2 years. apparently this cocktail is a neat fix for schizoaffective stuff, but i haven't seen anyone else on this site stating that they've been prescribed this mix. anyway, i have to agree with others that, at first, it seemed like the way to go. i'd had lovan before; it was an invitation to apathy, while it did clear the mind and let some work get going; the seroquel seemed to add some eagerness and some loss of worry to the mix; actually found myself going to the local markets. but that spirit's long gone. dread, angst, is only stronger day by day. like others have noted here, i've also started drinking heavily - not a drop for at least a year before going on this cocktail; now going for the vino-destructo like it was fruit juice - to blank out the ambient dread, the obsessive angst; to feel something more than desperation. there is no gift-of-life with these "happy-beans" - they just make us care some less that we've hit dead-end and that the fact is that this is it - or sleep or munch our way through it - somehow have to find another way of being self-effective (but then again, as if one hasn't tried all the scripts) - after much juggling, i reject the implicit idea, on this site, that "this or that drug is this or that bad" - we're all just going along in our little row-boat M 43 2 years
11/1/2009
Email
 2  To amplify the effects of sleep pil Shortness of Breath Drastic weight gain, dizziness, blurred vision, possibly contributes to my high blood preasure. On its own, it has no effect on me whasoever, I could take panado and get more response. Combined with strong sleep medication, it works well. WEIGHT GAIN is dramatic At 200MG I suffered dry mouth, little saliva, always thirsty, and rapid and unexpected weight gain within just 3 months. I want to stop using this but my mind convinces me that without it, my sleep medication will not work and my sleep pattern will be disturbed up to 5 times a night. I hope to increase my sleep medication the stop Seroquel just for a while to make sure I sleep through. How crazy is that - increase Dormicum 15mg x 2 per night to 45mg at night just to get off Seroquel. Whatever you do, consult a highly skilled and experienced psychiatrist in this drug and ask them to explain these effect before ever thinking it an option. I suffer for bi-polar, anxiety and depression and the best lesson in life is routines, schedules, work hard and sleep well. With good sleep and rest, I can manage my depression, anxiety is a devil on it's own and not so easy to manage. But I'm managing to remain in the main stream, be productive and soon will be off this drug. I should never have taken it to begin with. M 43 18 months
100 1X day
3/30/2018
Email
 1  Bi-Polar, BP Disorder I went from a size 8 to a 16 in less than 6 months. My hair comes out in handsful. I am on 500 mg at night. Have been for almost 3 years. I cannot sleep without it. I still wake up every hour or so for at least 20 to 30 minutes. I work 12 hours a day on my feet moving constantly. When I did this before seroquel I could eat what I wanted and stay in good shape. This drug has just about shut my metabolism down. My mouth is so dry that if I can't drink immediately, my throat starts shutting off. My lips stick to my teeth. This is a nightmare. F 43 2.5 years
7/8/2009
Email
 1  Afghan\veteran Became Diabetic\lost half eye sight, Damn drug pushing pysch doctors. Down from 800mg to 200mg in 24hr period, remember 73% of brain receptors are, in the stomach, symptoms of withdrawal are cold sweats, hot flashes, irritability, if your too sick to eat please drink water all day, last people who go cold turkey usually need anti-anxiety meds thruout your future years. Thats all, Thanks for your stories… M 43 1 years
400mg
4/11/2015

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