SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Bipolar I Extreme hunger, spent LOTS of time sleeping. I've had type 1 diabetes for over 26 years, Seroquel caused me severe insulin resistance so I had to take very, very large amounts of insulin. When I took Seroquel I'd have a period of good calm and then I'd become extremely angry. I'd get a dose increase and the same process would occur again. I ended up taking 800mg in the morning and 800mg at night. My diabetes was so screwed up. I ate cookies, candy, ice cream, cake, doughnuts, and just about every high fat high sugar food out there in HUGE amounts. I was compelled to eat huge meals/snacks and then eat again an hour later. I ended up at 256lbs then enough was enough. I now weigh 145lbs after quitting Seroquel. Seroquel is a tremendously horrible drug. Please be careful - the great sleep is deceptively delicious, but the other effects are horrible. M 38 8 years
8/2/2009
 1  Bipolar Fast & uncontrollable weight gain, endless hunger I took Seroquel 10 years ago when I was a lab rat for Astra Zeneca. I was young & naive and thought they knew what they were doing. I was 105 lbs when I started taking this and was up to 120lbs in just 3 months. My hunger would not cease. Round the clock I was so hungry. It was terrible. I'm not sure if it worked for my bipolar as I only took it for 3 months, but it wasn't worth it. The withdrawal symptoms were hell. Not as hellish as Effexor withdrawal but really bad. I was sick for 2 weeks after Astra Zeneca took me completely off this horrible drug. F 38 3 months
300
12/30/2015
 1  Tourettes and ADHD Brain was so wiped out the morning after taking first dose, I couldn't focus enough to read the morning news. Shortly thereafter, body had a horrible tic attack. The rest of the morning, my brain was a complete fog - sat at my desk at work and just stared at the papers in front of me, unable to read or comprehend anything. By far this the WORST medication I have ever taken. It should be removed from the market. M 38 1 days
8/24/2015
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 5  Anxiété généralisée et dépression Au départ somnolence constipation troubles de la mémoire prise de poids augmentation de l'appétit et grosse fatigue. Ça fait 3 ans que je prends ce médicament qui m'a changé la vie. Je dors mieux je suis stable et beaucoup moins anxieuse. Je suis passée de 300 à 200 mg récemment et je n'ai quasiment plus d'effets secondaires. F 39 1 days
200
4/4/2016
 5  Bipolar Drowsiness the next day for the first month, this subsided the longer I was on the medication. Constipation. Weight gain (20 plus pounds)My doctor has just prescribed Topiramate 25mg to help with weight gain Dose: 325mg Before taking this medication I went through about 4 manic and depressive cycles per year sometimes winding up hospitalized. I also had mixed episodes and alot of anxiety and racing thoughts. I also had trouble falling and staying asleep. Serequel ended all these symptoms. I was VERY afraid to try this medication. I was unresponsive to lithium. Before being diagnosed as bipolar I was diagnosed as having post partum depression (on effexor 225 mg). Previous to post partum I was diagnosed as depressive with parnoid characteristics (prescribed paxil, prozac). None of these medications worked. Serequel has been a gift from God. I feel like a whole person that can deal with the world as a normal person. Judging from the feedback on the forum this medication seems effective for those who are truly disabled by bipolar otherwise it is not worth taking. F 39 1 years
1/6/2010
 5  Bipolar Drowsiness the next day for the first month, this subsided the longer I was on the medication. Constipation. Weight gain (20 plus pounds)My doctor has just prescribed Topiramate 25mg to help with weight gain Dose: 325mg Before taking this medication I went through about 4 manic and depressive cycles per year sometimes winding up hospitalized. I also had mixed episodes and alot of anxiety and racing thoughts. I also had trouble falling and staying asleep. Serequel ended all these symptoms. I was VERY afraid to try this medication. I was unresponsive to lithium. Before being diagnosed as bipolar I was diagnosed as having post partum depression (on effexor 225 mg). Previous to post partum I was diagnosed as depressive with parnoid characteristics (prescribed paxil, prozac). None of these medications worked. Serequel has been a gift from God. I feel like a whole person that can deal with the world as a normal person. Judging from the feedback on the forum this medication seems effective for those who are truly disabled by bipolar otherwise it is not worth taking. F 39 1 years
1/6/2010
 5  bipolar disorder - rapid cycling nasal congestion every night at bedtime, hair loss, weight gain I can not believe how many people are taking this for insomnia! It has been the one medication that has been effective for the longest time (have been on more meds over the past 16 years than I can remember - most work for a short while then become ineffective). However, it is extremely powerful and I only take it as a last resort before lithium. To see people taking this for sleeplessness seems like using a sledge hammer to swat a fly - no wonder they are unhappy with the side effects. F 39 6 years
10/24/2009
 5  panic attacks, anxiety, depression weight gain, sore muscles (comes and goes..especially in upper back and neck), memory loss, word finding difficulty, weird vision problems, difficulty with attention, body movement is getting difficult (feel older than I am), hair is VERY straw-like, constant cravings and overeating, feeling HOT, EXCESSIVE SWEATING(embarassing) This medication worked very well. Helped me sleep and wake up rested and calm. No panic attacks at all!!! But, due to side effects and possibly worse ones coming on, I do not wish to take this regularly any more. I am weaning off and may take it on an as needed basis. I agree with others who have said that our healthcare professionals aren't telling us all the information before WE decide what meds to take. F 39 40 days
9/9/2008
 5  OCD Sleepy, but I take it at bed time. Weight gain - I put on 30lb the first year, but have since taken off 25lb without any real dieting. Along with Paxil, it has taken away all of symptoms of obsessive thinking and OCD. Can sit and concentrate with out intrusive thoughts. Sleep great every night. I was up to 300ml but am only on 50 now. I will not stop taking either med unless I have to. I finally have a normal life. It's been a great three years mentally. I'm getting divorced and not been depressed at all. M 39 3 years
8/9/2007
 5  PTSD paranoid personality insomnia some nightmares long sleep times I slept around 2 hrs a night before seroquel and was extremely paranoid After seroquel 10 hrs a night sleep and gradual lowering but not completely of paranoia M 39
7/26/2006
 5  bipolar disorder none..which is why i love it. NO...correction...it makes me very, very tired. That did get better with time, but I'm on a med that helps with that in the a.m.....so I don't even notice it now... first bipolar med I've taken that doesn't make me stupid F 39 20 months
1/1/2007
 5  anxiety, insomnia, depression, PTSD None that I note other than being too sleepy if I do not allow a solid 8 hours sleep after taking it. ** No weight gain at all and no increase in appetite.** In fact, since I started eating a diabetic diet 18 months ago, I've lost 30 lbs. Sleep, GLORIOUS Sleep! It definitley has a calming effect for me which has enabled me to reduce my valium intake. (always a good thing!) I do need to make sure I take it by a certain time each evening if I want to be up and at work on time the next morning. F 39 2 years
11/30/2005
 5  bipolar 1 primarily fatigue. I take a large dose (700 mg) at night and I go nite-nite very soon afterward! Then I take a smaller dose (150mg) in the morning. About 30 minutes after taking it I feel fatigued but that passes with the hour. The weight gain with Seroquel is generally less severe then with other anti-psychotics. I have experienced some weight gain but nothing that I havent been able to control with nutrition and exercise. i weigh a bit more but my mood is a whole lot more stable and life is much better than it was years ago!! I take seroquel along with Lamictal (lamotrigine) to aid in stabilizing my mood. Seroquel has been able to keep me from becoming fully manic and aids me in sleeping when I become hypomanic. It has been a life-saver for me! F 39 2 years
8/14/2006
 4  Bipolar II, severe insomnia restless legs/twitchiness, memory problems, problems "accessing" certain words and names. Constipation, irritablity. This drug is the only drug that ever made me sleep like a normal human. It shuts off racing thoughts and mental background noise like a swtich. I was heartbroken when I could no longer take it. The first time I took it I got resltess legs. This eventually got much worse and spread to my whole body until it started keeping me up all night. Although it stabilized my moods, it left me in a mildly crabby state and I developed a temper. I am now off it and I miss sleeping at night and having a quiet mind. Untill the twitchiness got so bad, I was doing quite well. M 39 4 months
10/15/2006
 4  PTSD, Sleep Disorder The side effects I’m currently experiencing are: feeling tired during the day and difficulties concentratin. Due to PTSD, I sleep very little and awake often resulting in 2-years of sleepless nights. Without question, the Seroquel has helped significantly with sleep to include remaining asleep throughout the night. My wife states, I move very little and have been snoring which is a relief to her knowing that I’m finally getting some rest. I don’t awake during the night to screams and images in my mind which we both are grateful for. I’m concerned about long-time usage and the difficulties I’ve experienced in concentrating. The benefits currently outweigh the side effects and I’ll closely monitor changes with my doctor to determine ongoing treatment. M 39 8 days
4/17/2007
 4  Bipolar1, Anxiety, Sleep Disorder Constipation, short term memory loss - Seroquil??? Not sure I started taking the fast acting seroquel. Gained weight quickly. After being on Abilify for two years gaining 60lbs with high cholesterol, my doctor switched it to fast acting formula, I experienced severe drowsiness immediately. Thats fine for me, but I was gaining wait and waking up groggy. So she switched it to the XR formula. I feel better than ever, actually loosing weight and not groggy in the am. Still wondering about slight confusion and very short term memory loss??? F 39 3 months
50MG XR 1X day
12/14/2011
 4  Chronic depression/anxiety increased appetite, occasional drowsiness/tired, improvement in sleeping, over-full sensation, continuously snacking. In 2003, I had major surgery for a pancreatic tumour (Whipple procedure), so I am not 100% sure about the side-effects as I have difficulty in digestion. What I did notice is an increase in hunger and an extremely full feeling after eating, and extreme hunger pains avery 2-3 hours. I sleep all-night now, but, have some pretty wild dreams and occasional dizziness. M 39 2 weeks
1/4/2005
 4  bipolar II, insomnia Initial side effects (stoned all day) were horrible, but have resolved. The first time I was started on seroquel, I stopped after a few days because I felt so hung over and stoned the next day. After several months, I agreed to try it again by starting out at a much lower dose. I'm now up to 200 mg at bedtime and sleep better than I ever have in my life (insomnia since infancy). Other than the initial negative side effects, my current dose isn't giving me problems; I have not gained weight on this drug and my lipids, blood sugars are fine. I'm currently titrating off zoloft and will be adding smaller doses of Seroquel during the day for anxiety. F 39 2.5 years
10/5/2006
 4  Bi-polar II Restless legs and the first night I had a panic attack, but I think it was from reading too many bad side effect reviews. I psyched myself right into a fright-fest. This forum has so many horror stories and this drug has been great for me. This has truly helped me balance out my emotions and my life. I do have some grogginess, but after about 3 weeks, it lessened. I sleep great now and before seroquel, I didn't sleep, which was leading me into a world of mania (it was still happy mania, but that's a slippery slope). This may not be for everybody, but for some of us, it is great. I am only on 100 mg, which is low. Also, there has recently been an article on anti-psychotics that people should look up: A Conversation With Nancy C. Andreasen Using Imaging to Look at Changes in the Brain By CLAUDIA DREIFUS New York Times September 16, 2008 F 39 7 weeks
11/10/2008
 4  bi-polap 1 I'm prescribed to take this med at night. This med has helped me GREATLY when it comes to sleeping. I don't mind the vivid dreams, I'm just glad I can sleep with almost no wake-ups in the night. One thing I did notice was that if I take my full dose at once, I get a feeling similar to restless leg, or more accurately, for me, restless shoulder, which doesn't happen if I take 1/2 dose, then the other 1/2 in an hour or so. The major problem I've had is WEIGHT GAIN...35lbs in 2 years. It seems that after I take my dose, I get strong feelings of hunger, so I end up eating late, which is likely part of the reason weight gain is a problem for some. It's a major case of "munchies". Why this med seems to cause "the munchies" I don't know, I just know that it's real. Unfortunately this sometimes leads me to fall asleep before I can get my teeth brushed. Which isn't doing my teeth any favors. F 39 2 years
5/24/2009

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