SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  bi-polar/mania Extreme Weight Gain, Extreme tiredness cant get up in the am! On the weekends I will sleep until the pm, literally will have to set the alarm to get up! I feel like this has been the worst drug for me since day 1! My doctor hasnt listened to me in the past about the weight gain, tiredness, etc. I have 1 more appt to see him, if he doesnt make a change for me I am going to get a different doctor. I cant live like this any longer. I have gained 50lbs in a yr, and that is enough to make someone depressed and everything that goes with it! F 32 1 years
5/3/2006
 2  psychosis, depersonalization extreme drowsiness, listlessness, apathy, poor memory functioning, feelings of lifelessness and vacancy Not too keen on this med. Started on it two and a half weeks ago, after stopping Risperdal. First "day" on it, slept for 36 hours straight (a small break for breakfast aside). Initially, helped me get rest. I had been waking up five to six times a night with anxiety and feelings of desperation. Now, feels like prison bars on my mind. Trapped, no escape. Listless, listless, listless. I pace a lot. I get bored with pacing. I lay down. I get bored with laying down. I pace some more. I get tired of pacing. I lay down again. Get bored with laying down again. Try to sleep, but am bored with sleeping. No, actually afraid to sleep, for no particular reason. Perhaps afraid of never waking up. Trapped feelings. More pacing. Get bored with pacing. Basically, bored with being bored. Bored with feeling like a lifeless husk. This is mostly the med. When I don't take it (skip dose), life starts returning, mind and focus and personality and alertness start return M 32 3 weeks
1/21/2007
 2  psychosis, depersonalization extreme drowsiness, listlessness, apathy, poor memory functioning, feelings of lifelessness and vacancy Not too keen on this med. Started on it two and a half weeks ago, after stopping Risperdal. First "day" on it, slept for 36 hours straight (a small break for breakfast aside). Initially, helped me get rest. I had been waking up five to six times a night with anxiety and feelings of desperation. Now, feels like prison bars on my mind. Trapped, no escape. Listless, listless, listless. I pace a lot. I get bored with pacing. I lay down. I get bored with laying down. I pace some more. I get tired of pacing. I lay down again. Get bored with laying down again. Try to sleep, but am bored with sleeping. No, actually afraid to sleep, for no particular reason. Perhaps afraid of never waking up. Trapped feelings. More pacing. Get bored with pacing. Basically, bored with being bored. Bored with feeling like a lifeless husk. This is mostly the med. When I don't take it (skip dose), life starts returning, mind and focus and personality and alertness start return M 32 3 weeks
1/21/2007
 2  BI-POLAR SCHIZOAFFECTIVE Loss of coordination. Losing center of gravity and falling down on occassion. Extreme blurred vision. Slurred speech on some mornings as I only take it at bed time. I am on 300Mg currently M 32 3 months
2/13/2006
 2  sleep No side-effects. Withdrawal causes problems. Switch to zyprexa 20mg and cold turkey it. Alternatively increase seroquel to 600mg and stop it but doses above 400mg make seroquel work like mild SNRI and are not long-term. Never start antipsychotics voluntarily. Always use neurologists and sleeping pills. M 32 2 years
400 1X day
5/16/2013
 2  Bipolar - paranoia/anxiety No motivation, lack of concentration/focus, feeling stupid, occasional seroquel hangover/difficulty getting out of bed in the morning I have had an on again off again relationship with this med over a number of years I have previously taken daily doses as high as 200mg but that turned me into a zombie. I don't think seroquel agrees with me even on 25mg a day I still get the side effects I listed. No where near as severe as when I was taking 200mg but it still messes with my cognitive functioning. That having been said given my previous experiences with other anti psychotics seroquel's side effects are mild. I'm going to stop taking it though I can't keep up with my peers seroquel is making me look an idiot. M 32 3 months
25 1X day
8/27/2010
 2  Bipolar I was taking lamictal Lexapro for my bipolar which was working well but then I developed a rash so I had to stop. My dr switched me to Seroquel and the sides started within about a week of starting. To make a long story short... Bad nightmares, weight gain (I am 5'6, been 118 lbs for years, healthy eating, regular appetite and gym) within about a week of starting this med I started craving sugar and carbs in amounts that shocked me!! I gained a total 12 lbs in the 2 months I took this med!!! I was always tired and my mood felt very flat, kind of like a zombie. Definitely felt very drugged. Long story short, I did not like seroquel and I will never take it again!!! Really not happy with Seroquel at all.... F 32 2 months
11/3/2008
 2  depression/insomnia Increased fasting blood sugar levels/prediabetes. Weight gain (25 pounds) Anyone else experience increased blood sugar levels? M 32 1 days
7/26/2007
 2  anxiety increased general anger and lowered threshold for lashing out at people. I'm sure this drug is wonderful for many people but for me it made me quite angry and quick to lash out at people. Although my dr. thinks my prob. is anxiety I suspect it is depression and I suppose the seroquel just made me less anxious about expressing my bad mood. lol. M 32 1 months
12/11/2004
 1  Bipolar disorder Horribly Lathargic, sleepy, numb, loss of motor skills and speech I read this forum before trying seroquel. But my sleep was horrible and my mania was still wacky, because my wonderful lithium had not kicked in yet (doing much better now, a few months later). Anyhow, I just want to warn others that I hated seroquel. I lost myself for a few days from it. I felt sick and could not function at all. So PLEASE, if you want to give it a try, make sure you have some time off to do so. I was on the smallest dose too! F 32 3 days
5/1/2007
 1  anxiety weight gain, muscles pain, sedation i was put on this drug for anxiety and sleep disorder( couldnt sleep. The drug is a weigh gainer! the only GOOd thing it does is I get a full nights sleep, but the next day i have muscle cramps , rapid heart beat, feeling of cloudyness... i cant figure out whats more important a good nights sleep or feeling horrid the next day F 32 3 days
5/15/2007
 1  Anxiety, depression, insomia First dose made me a zombie - a literal zombie the day after. I could not make sense of words to read, I couldn't do basic math, I felt like I wasn't even living in my body. Then the WORSE side effect started - severe leg cramps. My leg muscles were so tight and I was in so much pain I spent most of the night after I took the second dose crying in pain and ended up having a panic attack. Called the doctor in the AM, he told me to stop immediately and phoned in a muscle relaxant for me. Worst drug reaction I've ever had, even worse than an antibiotic that made my face swell. I now list this among my allergies. This drug may be good for some people but I really think this is prescribed far too freely considering the side effect profile and really should only be restricted to people who have ACTUAL mania and psychosis. F 32 2 days
50mg 1X day
9/12/2012
 1  Bipolar II NOS Where to start.... Side effects did not start instantly, they took time (weeks) to build up, and when I stopped it took time (weeks) to abate. 1. Sweated like a race horse when I slept. Woke up with sudden gasps and heart racing 2.Had a very difficult time urinating, low flow, and couldn't shut off the tap, just kept dripping 3. I could not orgasm!!! .... that alone would make a sane person crazy Was prescribed this for Sleeping & Bipolar II NOS. HORRIBLE SIDE EFFECTS - In my case, it didn't particular effect my mood or my sleep. Even if it did, the side effects more than negated any positive change. M 32 8 months
Unsure 1X day
8/26/2012
 1  Schizophrenia I took Seroquel for 3 years to treat schizophrenia. But after I discontinued it I began to experince delayed ejaculation. How long will this last? Will it go away by itself or do I have to get on some other medication? Is there a solution to this? Please help. [email protected] M 32 3 years
9/27/2006
 1  Extreme anxiety, psychotic episode My drives have been deadened, I have no inner life (there's a horrible feeling of absence and numbness from the top of my shoulders down to the bottom of my loins, as though my core was somehow gutted), my consciousness doesn't feel attached or anchored to my body, I can't experience any excitement or genuine emotions, I feel hollow and empty, I've been made impotent Between the Seroquel and the Risperdal (which I was on for nine weeks before starting Seroquel) my life has pretty much been destroyed. The'side effects'(consequences, really)started a month after starting Risperdal, and have only gotten worse with time...I'm down to 50 mg of Seroquel a day (from 400 mg) and have noticed ABSOLUTELY NO IMPROVEMENT in the side effects I mentioned...like I said, things only seem to have gotten worse, and there doesn't seem to be any end in sight...I feel helpless, hopeless, and terribly desperate at this point... M 32 3.5 months
4/22/2007
 1  Eupd Raised prolactin levels, change in menstrual cycle. Extreme fatigue, loss of eyesight. Confusion. Weigh gain. Headaches, blurred vision and confusion F 32 4 years
100mg 1X day
9/30/2020
Email
 1  Bipolar 2, clinical depression Gained weight rapidly, bedridden slept 13 hours, didn’t care for anything felt like I was paralysed. I thought this time I was getting the help that I deserved after taking every med under the sun non worked. It did stop me crying and numbed me emotionally but I felt very depressed and suicidle and sad that I couldn’t look after myself. If life upsets you believe me you will have a crazy episode but if your in bed all Day you feel nothing except worthless useless and not wanting to be alive but your so sedated you can’t be bothered to kill yourself. I had panic attacks and stopped breathing many times in my sleep. The tablet will hit you If you are making something to eat then suddenly your on the floor you cannot move the tablet sometimes puts your body to sleep before your mind and sometimes it feels like someone is giving you a lethal injection and you feel like your dieing whilst going to sleep it’s awful. It’s 4 days going cold turkey my nurse did not recommend it but they do nothing to help except increase the doses. My eyes and hearing and very heightened noises light is painful constant nausea my head feel awful can feel the drop in my brain feels like a painful black hole. Stomach cramps and constant pain, sweating. Crying very emotional but I’m feeling a little better despite that feel a bit more motivated to get out of bed and do simple laundry 32 6 months
300
11/24/2019
Email
 1  Bipolar/Depression It didn't really help with my problem, just made me tired all the time. Realized, I don't need to be on it anymore. Weaning off of it slowly withdraws are horrible, so dizzy and nauseous. It's a very serious drug to come off of! Please give yourself time to come off it! I personally don't recommend this drug at all, because of what it does to your mind and body while on it. Hope this helps! F 32 3 years
200 Mg
8/26/2014
 1  bi-polar/ aniexty.insomnia Hard to wake up in morning, gained about 45lbs, spaced out ETC My doc put me on this took 600mg nightly before bedtime, took for about 3 1/2 years um stopped on my own he said no not good thing to stop by yourself....he said I would have bad side effects blah blah blah I stopped myself took ocntrol yes I did have side effects / withdrawls from not takeing it HOWEVER I am now back down to a normal wieght lost all the weight I gained and sleep just fine also. I am not saying for everyone it will be this easy but PLEASE DONT GET ME WRONG IT TOOK A GOOD MONTH FOR ME TO BE BACK TO "NORMAL , MYSELF " It took awhile for it to get out of my system and WOW what a diff/I feel great and look great I control my mood swings ...HECK MAYBE HE THOUGHT I WAS SOMETHING I WASNT ... I JUST KNOW NOW THAT I STOPPED TAKING IT I AM BETTER INSIDE AND OUT F 32 3 years
11/13/2009
 5  Bipolar/Anxiety/depression Groggy for the first couple of hours in the morning, tons of energy in the afternoon (thats good!)Usually knocks me out 20mins after taking it at bedtime. Also taking Ativan when needed for anxiety attacks. I have been on Seroquel for 3 weeks, this medicine has been a life saver for me! I started out on just 25 mg a night before bed, then moved up to 50 mg's. I have actually LOST weight, 5 lbs so far (I put on 15 when my depressive episode returned). For so long I thought Dr's just didnt understand what I was going through, they continued to try me on different anti depressants, all of which made me more anxious and freaked out, to the point I wanted to hurt myself and others! Finally with my Therapist and new Dr, came to my Bipolar diagnosis. Seroquel has helped me want to be productive and actually LEAVE my house again, it has mellowed out my severe mood swings, its helped with my anxiety attacks, but we are still working on that. Im not saying its for everyone, but for a person like me who kept getting the typical depression diagnosis over and over again, I cant say enough good things!!! F 33 3 weeks
4/28/2009

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