SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Age from youngest to oldest (reviews with no age reported listed first).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  mood disorder/OCD I've been on seroquel for about a month. I've already gained 7 pounds, which is not a good thing. I was up to 150 mg at night, which helped me sleep all night, but made me feel like a zombie all day. I crave junk food constantly and eat all the time. I have little energy. I'm also on 20 mg. of Lexapro and 200 mg. of Lamictal and 200 mg of Wellbutrin. I'm lowering my dose gradually of seroquel so I can be done with this weight gain. I think I'll go back to Trazadone to help me sleep and hopefully that'll work. My main issue is that during times of stress (most of the time) I have a lot of "noise" in my head. Music mostly. Loud and annoying and I grind and tap my teeth along with it. I'm doing this all while maintaining a "normal" life as a stay-home soccer Mom. I can't make it stop and sometimes I beg myself to make it stop. Weird, I know. What else might work for that besides Seroquel? I feel like a science experiment right now. Any thoughts suggested. F 40 5 weeks
5/21/2007
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 2  bipolar mania , major insomnia lack of motivation, extreme depression, headaches, hypotension, increased pulse, dizziness, weight gain, dry mouth, constipation, personality change, puffy gums, no interest in activities other than sleeping. I would love to know how people sleep after having huge insomnia before seroquel as it is the most potent sleep inducer known to mankind. F 40 9 months
7/7/2007
 2  Sleep disorder, anxiety Agitation, Anxiety, Zombie like feeling the next day, insomnia. M 40 4 weeks
4/4/2003
 2  bipolar rapid cycling psychotic weight gain and associated depression, uncontrollabe craving for sugar. I take 100mg at night. Used to help me sleep now it makes me sleepy sometimes then I also wake up in the middle of the night not sure how it will affect me at times. Depression and social withdrawal due to weight gain and paranoya of people harming me. I have trouble making decisions not passionate about anything except eating sugar. F 40 3 months
10/24/2007
 2  Anxiety/depression Dry mouth (not a big deal), Zombification (not a huge deal), Anger/rage/ lashing out (very big deal) This medication put me in a very dangerous state of mind though not at its peak in my blood, rather in the morning after having taken it multiple times through the prior day. I assess my rage side effect as being some type of withdrawal from Seroquel as opposed to a direct effect of the drug. This happened only this morning and I have yet to speak with my DR. Fortunately, I am writing this from home and not from a prison cell. I would recommend people pay close attention to their moods and self control while getting used to this medication. M 40 1 weeks
10/11/2005
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 2  Bipolar -Mixed initially very calm, quiet inside later i was so grogged out i couldn,t function. Always hungry. Can,t get out of bed in the morning F 40 98 days
1/23/2007
 2  Insomnia, over-sensitivity, stress A drunk feeling and bad quality sleep. Difficulty to wake up. Groggy feeling all day. Greasy skin. And maybe other things, who knows?! A word of warning! I was taking Seroquel at night 25 mg and then 25 mg on waking up after five hours. I wasn't sure it was reducing my anxious feelings but I did get a sleepy feeling from it. I was, HOWEVER, also taking other medicines to help me sleep (zopiclone, a cousin of benzoes, at first and then tematsepam, a benzo, and Somadril, a muscle relaxant, for a while because the zopiclone didn't seem to work effectively anymore). After 7 months I had to taper off on the strong sedatives as I had grown tolerant to them. That's when I noticed that Seroquel actually produced really bad quality sleep! No matter how many hours I slept I kept feeling underslept. The situation was only stabilized when I cut down on Seroquel and started on zopiclone again. Now I use about 25 mg per night only. I wouldn't recommend more than that. F 40 8 months
12/26/2006
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 2   On going off all my other medecines EXCEPT Seroquel I realized the quality of sleep was rapidly decreasing and I was going crazy from not ever feeling rested! Eyes hurting and tension from lack of decent, deep sleep. Even with sleepingpills the quality is better. I forgot to mention in my earlier statement that I used to be on Zopiclone as wELL as amitripyline on the same time that I was taking Seroquel in the night time to help me slepp. So when I tapered off all the others expect Seroquel the bad quality of sleep showed up. I went off amitriptyline because a doc wanted I try cymbalta, but it was poison to me so I went back on amitriptyline and doubled the dose. It's supposed to better the quality of sleep and reduce pain a bit, so I suggest you take that rather than seroquel! I know the docs say a lot of bullshit about the safety of seroquel but I'm sure it's more slyer than any of the straightforward and maybe old and proven sedatives! F 40 8 months
12/26/2006
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 1  Panic Attack - High Anxiety ABSOLUTELY THE WORST MEDICATIION THAT I HAVE EVER TAKEN. DO NOT TAKE. Restless Legs; Tremendous Hallucinations; Had to crawl on hands & knees to go to bathroom; Over Relaxed my muscles to a point where my old-dislocated shoulders were pulling themselves out of there sockets while laying down; increased panic attacks for short time; and Over-slept (uncomfortably) off and on for 2 days. Very groggy for 48 hours. Later, I felt my kidneys having a hard time processing medication. Would not recommend. Zombie. Laziness and increased eating. M 40 5 days
12/28/2006
 1  Insomnia Blurred vision Palpitations Could not swallow Loss of self-control – smoking; major eating Lethargy Apathy Memory loss Hair loss Fatigue Weight gain (not very much but bothered me lots) Dry mouth The WORST drug I have ever taken. Taken for sleep. Ended up taking 25 - 50 mg. nightly. Would knock me out BUT got palpitations, Would need crackers then sweets (for no reason) including chocolate (which I hate). (I would have eaten a cardboard box). Could not swallow (even fluids) Finally would go to sleep and wake up breathing chocolate. Last straw was I have 2 cats and chocolate is toxic to cats. I dropped some chocolate and normally would have searched the floor with a magnifying glass but on that night (4:00 AM) I did not care enough to look and just covered area with a sheet. (December 26, 2010) never took it again. Question: Although I was *only* on 25-50 mg. nightly, it had MAJOR effects. It has been 3 months! But 2 weeks ago, I developed severe bone / muscle / joint pain (hip, sacroiliac area) and ankle swelling to the point I cannot hardly walk or get to my doctor due to pain. Could this be a late withdrawel reaction? F 40 7 months
25 - 50 MG 1X AN
3/27/2011
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 1  depression Seroquel has made my life miserable. I had the worst leg pain that kept me from sleeping altho I walked around like a zombie trying to stretch or walk around while experiencing this leg pain. I no longer take this medication. Haven't had the leg pains at all... F 40
400 MG 2X day
11/3/2011
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 1  insomnia MAJOR weight gain(22 pounds in 2 1/2 months!) Unreal hunger. Zero energy. Constant hungover feeling. Severe dry mouth. Swelling in hands and legs. Restless legs. Nightmares. I could go on and on. Worst drug I have ever been on. With all the side effects this drug seems to cause people...why the hell is it even prescribed in the first place? I am off of it now and sleeping crappy again, but I'll take that over those side effects anyday! 40 2.5 months
10/21/2007
 1  insomnia I took it before bedtime and had extreme restlessness and couldn't lay still, was extremely hungry and had to get up to eat, and it took longer to get to sleep than usual. I eventually did get to sleep and woke up groggy. I reduced the dose and had less extreme side effects but it still made my insomnia worse M 40 12 days
2/10/2008
 1  depression and insomnia The worst thing I've ever done. I want my life back. Went cold turkey because I was becoming diabetic from taking seroquel. This is my first time taking an antipsychotic ever. Anyone with suggestions please post. Feeling like a zombie everyday. I feel like myself maybe for an hour a day. People are noticing a difference in my conversation. Help!!!!! M 40 1 months
300xr
3/27/2015
 5  post traumatic stress & anxiety Craving for sugar resulting in 14lb weight gain and after a year of taking it, my cholesterol has been found to be high. Seroquel was my saviour during a very difficult time. It gave me a break from my constant anxiety aswell as a break from my overactive mind. It helped me to keep calm like no other medication has. I would recommend it for temporary use but not long term. I did feel like a zombie but would rather that than suicidal. I came off gradually because of the weight gain and high cholesterol. Had a rash initially and itching all over aswell as a few sleepless nights but 2 months down the line, I'm not doing too bad although I haven't lost a pound in weight even though I have halved my calories. Can't help but wonder if Seroquel has changed my metabolism permanently. F 41 365 days
8/31/2009
 5  insomnia my trigycerides went thru the roof so i had to start taking cholesterol medicine. VERY vivid crazy dreams. i take it to help me sleep. i take 12.5mg at night along w/10 mg of xanax...it keeps me asleep all night and i love the dreams. it's almost like going to the movies! it has been a life saver because i couldn't sleep before. F 41 3 years
3/21/2008
 4  Insomnia and PTSD and depression Restless legs and upper arms; involuntary muscle twitches when at rest. The restless legs SUCK, they happen when I take more than 200 to 250 mgs. I'm seeing the doc this week to find out if I have to go off it. I HATE that side effect and worry about the twitches being irreversible. It helps TREMENDOUSLY with falling and staying asleep, which is what it was prescribed for. I felt depression lift about a week after starting the drug. I am happy to be on it but worried about side effects. It has increased my hunger, which is good because I need to gain about 10 lbs. F 41 1 months
12/31/2008
 4  Sleep trouble. Too groggy the next day if take too much. Can last many, many hours... I take Seroquel to counter the insomnia side effects of Wellbutrin. It definitely helps me stay asleep longer. HOWEVER I seem to be extremely sensitive to it and can take only mini amounts. I take the 25mg tablet and cut it into quarters and then try to make those little pieces even a little smaller. So, I'm taking only, like, 5 or 6mg of it. If the piece is too big I will still feel sedated and somewhat hung over way into the next day. The effect can last more than 12 hours, for me anyway. It definitely works but can be too sedating. F 41 3 years
3/19/2009
 4  bipolar sideeffect when taking SSRI Wierd feelings at first like derealization, take at night and get me to sleep at first in 20 min. Now 1-2 hrs. Also had neck and back spasm when tried to increase dose to 150Mg went to emergency room as I couldnt move neck or back Dr. said reaction to seroquel he sees it all the time and gave me 5mg of Diazepam and a shot in butt of benadryl (50mg) told me to go back down to 100mg and take benadryl 50mg a day....spasms are a bad side effect scared I might have a spasm in heart muscle seroquel works pretty good on mood but sometime you still have mood break throughs M 41 6 months
2/4/2009
 4  bipolar / insomnia I slept very well on 25mg at bedtime. I had to be sure I took it early enough so that I would have at least eight hours to sleep, otherwise very sleepy in the am. Problem is I developed mouth puckering, which my md said could be a side-effect.(dyskinea) I'm disappointed I had to go off. Hoping maybe I only had the mouth puckering because I was also on Prednisone for asthma. Maybe when done with prednisone, can try again. F 41 10 days
5/26/2005

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