ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  persistant scarring acne Depression, un-provoked anger, crying and mood swings, dry lips, skin, mouth, nose, and throat. Cleared up acne very quickly and effectively, but side effects may not be worth it! Drink at least a gallon of water a day & constantly apply moisturizer to your lips and skin. I lost my voice if I didn't constantly drink water while on accutane. My lips would swell up unless I put Aquiphor gel on them every hour. And I didn't believe that a pill could really change your personality, but this one seems to. I stopped taking it a month early but still have panic and anger attacks. It is hard to drive without road-raging and I lose patience with people like never before. I think that it made me defensive, insecure, and almost suicidal. It wore me out, but cleared my skin and scalp better than the last 13 acne meds I have taken. I don't know if it was worth it, though. I wouldn't recommend this to anyone unless they are very carfully monitored bc I really think it causes depressed/suicidal thoughts in some people that can linger even after you are done with the pills. F 27 4 months
10/24/2006
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 3  persistant acne chapped lips, dry skin, thin skin it was a mircle worker for the first 9 months then my acne came back worse F 15 6 months
5/8/2006
 3  Cystic Acne for 30 YEARS Dry lips; some dryness to face; dry scalp; joint pain; emotional sensitivity. Started at 20 mg 1st month; 40 mg 2nd month; 60 mg 3rd month and progressed now to 80 mg 4th month. I'm 5'7" & weigh 135#s. I was bumped up in dosage because my skin was still oily. Still get a cyst now & then, but they only last about 5 days instead of weeks. Major side effect is JOINT PAIN which I never had before, including hips, shoulders, neck, legs & feet. I move like I'm 75 - slow and heavy. Another side effect is emotional sensitivity. YES, this drug does cause emotional upset. The best way to describe is PMS 24/7 (nothing too serious, just don't look at me cross-eyed ;) My main concern is Joint Pain. Why? And will it go away????? Can anybody tell me. . . F 43 3.5 days
1/1/2007
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 3  Cystic Acne for 30 YEARS Dry lips; some dryness to face; dry scalp; joint pain; emotional sensitivity. Started at 20 mg 1st month; 40 mg 2nd month; 60 mg 3rd month and progressed now to 80 mg 4th month. I'm 5'7" & weigh 135#s. I was bumped up in dosage because my skin was still oily. Still get a cyst now & then, but they only last about 5 days instead of weeks. Major side effect is JOINT PAIN which I never had before, including hips, shoulders, neck, legs & feet. I move like I'm 75 - slow and heavy. Another side effect is emotional sensitivity. YES, this drug does cause emotional upset. The best way to describe is PMS 24/7 (nothing too serious, just don't look at me cross-eyed ;) My main concern is Joint Pain. Why? And will it go away????? Can anybody tell me. . . F 43 3.5 days
1/1/2007
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 3  acne really dry lips, dry eyes (contacts), bloddy nose, sad or crazy moods Accutane cleared my skin about 75% in the 2 months I was on it. I was really happy with how it was working and the side effects are easily tolerable except they aren't kidding when they give warnings of depression! My sanity is worth more than my vanity. Also, not many people mention how expensive the whole process is! From getting on the pill to blood work to office co-pay's...this is an extremely costly process, at least it was for me. F 24 60 days
11/28/2005
 3  moderate, persistent acne My face did clear up quite a bit. Its not perfect but better. The major side effects that I experienced were dry lips (you can't smile easily without lip balm), dry eyes, dry inside my nose, and dry skin on my hands. My skin never peeled or flaked anywhere though. My hair and face went from very oily to almost no oil production. Now that I am off Accutane my skin and hair went back to oily but not quite as bad as before. My skin is still pretty clear but I chalk that up to the fact that I stopped touching my face or messing with my acne altogether. For me the side effects were much milder than I had expected. Not once during my treatment did I feel depressed. I felt the same as normal. I have seen Accutane work for many of my friends. For me it only made a subtle difference. I have also seen some of my friends seem a little more sad or emotional than normal while on Accutane- but these are also the friends who were emotional and sad before they got on the Accutane. Maybe people who are already sad should avoid taking it. Maybe it heightens the sadness? F 24 5 months
2/6/2006
 3  Acne Dry face(flaking), severly chapped lips, dry scalp and hair loss, lower back pain, dry nasal passages. The face-flaking isn't really a big deal. It's just a bit annoying since I wear make-up and you can really see my dry skin. I've just been putting a mild lotion on everytime I get out of the shower and when I wake up in the morning. My lips kill. They peel and crack and just loathe me. Chapstick has become my new best friend since I've been taking Accutane. My scalp has become dry and flaky. I just wash it with just conditioner everytime I shower instead of shampoo. Conditoner still has alcohol in it so it still somewhat cleans your hair, but doesn't dry your hair out as much. My hair has beenn falling out a lot too. But that's not really a big deal to me. My lower back gets sore not when I'm active, but when I lay down and rest. It doesn't last long and it's a good excuse to have your friends massage your back. The only time I had a nose bleed was when I was sick and was blowing my nose a lot. Other than that, my nose hasn't really given me any problems. I keep some nasal spray in F 16 3.5 weeks
8/25/2006
 3  acne, back acne very very dry lips and nose, to the point of bleeding (Eucerin AQuAPHOR is the very best thing you can use for your lips and nose. not only does it keep some moisture in, it heals the cracks and sores. it will be your best friend...forget any lip balm or chapstick, even blistex...not so good for you) also experienced pain in joints (esp back and ankles), extreme dryness on hands and arms and face. flaking skin especially on face. my skin has become like a sponge, and all of the lotion and cream i put on, disappears almost instantly and the flakes are back. its a small price to pay for clear skin and peace of mind. depression and anti-social behavior more noticeable my second time around... this is a wonder drug, but it comes with its fair share of really bad side effects. for me, the results outweighed any of the side effects...i have taken it once before about 3 years ago...my face looked really great for about 2 years, but my acne came back and i decided to take accutane again. so far, i am most excited about the acne on my back clearing up. for the first time i am able to wear spaghetti strap shirts. really exciting. :) i have noticed that my ankles and my back are really achy, and i didnt experience that the first time...i wish i wasnt this time either, but its not terrible. F 23 3 months
2/11/2007
 3  Cystic Acne Dry lips, eyes, dry earwax, increase in acne, mood changes, crying spells. I got angular cheilitis on the corner of my mouth, depression, and my acne has gotten much worse...but I am hoping it will get better since I'm only in the third month. F 25 3 months
12/28/2006
 3  Severe Acne dry lips, headaches, stomach aches, vomitting, itchiness, and dry skin mostly on my face. I never had a problem with acne really my entire life until a year ago. It started on my back and has now moved to my chest, neck, and face. I never knew how having acne could impact my life. I honestly don't leave the house sometimes. I don't know how many times I said F 26 10 days
8/6/2005
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 3  Nodular/Cystic Acne Extremely dry eyes and mouth. Severe acne flare up during the first several weeks of treatment. Joint and bone soreness. I have been off Accutane for about a year. The first six monthes following the treatment was blissful - my acne was completely cleared up. However, I did have to get my tear ducts plugged because the "dry eyes" symptom never went away and the night blindness persists as well. Now, a year later my hair is just as oily and smelly (if not worse than before) and I have cystic nods pretty consistently. My skin has also gone back to being greasy and oily again. I am considering taking a second treatment of Accutane but I had such a bad experience with the side effects before; I am very concerned about pursuing such aggressive treatment again - I don't think my body can take it. This is a very powerful drug - although I was initially pleased with the results, I am not sure the severity of the side effects is worth it. F 23 6 months
12/4/2005
 3  acne Was on a 30mg for 6 months, amazing results for acne, however, it was temporary. I have to go back on it. My side effects were horrible - constant nose bleeds (heavy bleeds) mood swings and I'm currently still suffering from depression. See a counselor if you wish to take this drug. F 20 6 months
30mg
9/1/2013
 3  severe acne on my cheeks :'( dry lips n face, rectal bleeding, skin rashes on hands,mood swings,redness of face which makes it seem like it is irritated I am on accutane since nearly 2 months I guess I will be taking it upto 6 months. I am already going through so much of side effects of this drug...recently, i have developed skin rashes n rectal bleeding about which i am gonna talk 2 my doctor when i will visit him after some days...rest is alright...i also get angry a bit fast these days n have mood swings...moreover, my face gets red so fast these days that it makes my face seem so irritated!! :'( i really hate this side effect to the fullest! i have no clue if my face is gonna clear up n if this med is worth it...it will be known with time...hope i get better soon :( F 17 6 months
40 mg 1X day
3/27/2011
 3  Acne Dry Chapped Lips, Extreme Stiff neck and pain in neck, dry nose, but no bleeding So far I am liking the results. If I do "break out" It seems to dry up really fast. The stiff neck thing is becoming more and more of a problem. It has been going on for a week non stop. In the morning I can hardly lift my head off my pillow and have to turn my whole body since my neck is stiff. Im trying to grin and bare it. Just hope it goes away. F 28 30 days
40mg 1X day
9/27/2011
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 3  Severe acne Dry lips, soar back, overall very few side effects I am currently still on accutane and so far I've been very pleased with my results. I am only 18 but my issue is will this harm any babies that I plan on having later on down the road like 10 years or so from now?? F 18
60 1X day
5/17/2010
 3  cystic acne + regular acne Dryness: face, nose, arms, legs, vagina, scalp, nails, hair and especially lips. Dried bloody nose, fatigue, moody/emotional, hair loss, poor posture, lots of joint pains, headaches. I no longer have any acne but I have lots of scarring on my face, arms, and back that hasn't gone away. I'm supposed to be on a 6 month course but I don't see this coming to an end anytime soon. I had to stop working out because my joint pains increase dramatically when I do. I have a lot of side effects and just want this to be over. I'm very afraid it won't work :( F 20 4.5 months
60 MG 1X day
6/28/2010
 3  severe acne & scaring. extremely dry lips and face, blood in stool, high triglycerides which id never had before, mood swings, depression, peeling under finger nails, sty's on my eyes, severe joint pain that still has not gone away after 6 months off of accutane. the doctors never warned me of all the side effects. the doctors were very worried about my high triglycerides . i got very anger a lot for no reason. now i have to see a chiropractor for my hip pain from accutane. i still have spots on my face from the pimples i popped in the past and around my period i still get break outs. im not sure if i would recommend this drug to anybody i know. F 17 5 months
30mg 2X day
7/15/2010
 3  hard knots on face (acne) dry lips /muscle aches Fifteen years after taking accutane I now experience severe abdominal and lower back pain. I have horrible headaches, depression, hair thinning, muscle pain,bleeding hemmorhoids, high blood pressure, diahrrea, constipation, diverticulitis, etc. YOU NAME IT!! I am looking into the suit against them. I have always been super healthy but am beginning to attribute my problems to accutane use. F 49 180 days
1X day
7/30/2010
 3  Severe Acne dry skin, dry lips, muscle/joint pain I have taken 3 rounds of Accutane since I was 18 years old. I am one of the few patients who took this drug who experienced very mild side effects. Although my skin was great when I was on the medicine after each round my acne came back. I do not recommend taking multiple rounds of Accutane just because the long-term side effects are virtually unknown and the results are not guaranteed. F 24 6 months
30 2X day
7/30/2010
 3  cystic acne Dry skin and lips. Bloody nose once or twice. I have been taking generic acctune (claravis) for 3months now, I have 3 more months to go. I could see a change in the first month taking it. In the first month of taking it I did not have any cysts until the last week when I got my period one popped up. In the second month all black heads have disappeared, and I did not have any cysts, Although I have had some pimples here and there. I am almost done with my 3rd month of treatment and still no cysts. I do have scaring from years ago messing with my acne. My dr told me it would help with scaring so we will see within the next 3months. Other than that I havent had any other side effects. No depression, anxiety, or suicidal thoughts. Only a lil bit of back pain and muscle spasms in my neck. F 23 90 days
40mg 2X day
9/21/2010

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