ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  acne vulgarus bad backache,mood swings,sore joints,nosebleeds,crying spells,chest pains,itchy skin,dry skin,hair falling out,tiredness!! i went on holiday during my course and was fine with sun!no sensitivity..although i have 2 jobs and attend college full time studying hairdressing.im standing constantly think thats adding to the back/joint pains..really tired at times..i would advise anyone who bleaches their hair (on scalp) to be really careful!!! too much to handle!!had few odd breakouts.although my confidence has got much better glad to be back to my old self, partying again id recommend this treatment to anyone!!!!!!!only 2 months in to my course x F 18 4 months
5/31/2008
 4  moderate persistant cystic acne dry skin, lips, and eyes, fragile skin, irritability, joint pain, dehydration, reduced night vision, fatigue, photosensitivity, diminished sex drive, breathlessness with physical exertion. The side effects may seem bad, but they were not unbearable. I loved being able to go almost an entire week without washing my hair. Sebum is virtually non-existant even two weeks after being off the medicine. Side effects have almost completely diminished. I should have done this sooner and encourage others to at least try the drug if needed. You can stop at any time. The only thing I did not like is the iPledge system. It's a PITA! F 31 4 months
8/29/2008
 4  cystic acne all over body dry, painfully cracked lips (at times to the point of bleeding); dry, flaky, itchy skin and scalp; constant dehydration; severe acne flare-ups I have been on accutane twice. Each time, I took 40mg twice per day for 5-6 months. The first time, my acne flare-ups and side effects were awful and lasted pretty much the entire course of taking the medication. About a year later, I took my second course and the side effects were not nearly as severe (however I did have scarring). My acne is SO MUCH BETTER, but I am considering a 3rd course because I still do suffer from cystic acne. *Use Aquaphor (can be found at any drug store) to help with dry lips/skin *Use a homemade mask of alvacado and mayo once a week to help with flaky scalp *Drink plenty of water! F 24 2 times
9/6/2008
 4  Mild but persistent acne The most annoying side effect was the build up of bloody boogies in my nose. They would stick to the sides of my nose and when blown out, would tear the skin and cause bleeding. Then that bleeding would cause a scab and it turned into a bad cycle. I had NO mood swings from Accutane, this might be because I started a Vitamin B-Complex, which is supposed to help with mood swings. It was annoying that I couldn't get my eyebrows waxed during my Accutane cycle. I tried once, and it ripped off my skin. Of course, I couldn't go anywhere without chapstick the whole time I was on Accutane, but I could still wear make-up on my face without flaking skin. The MIRACLE lotion is Cetaphil -- get the one for the body and use it on your face, trust me. It didn't irritate my skin and provided enough moisture. I would recommend Accutane to everyone suffering from acne. My acne was not severe, but persistent. I would get a few big zits every month, and I had BACNE, which was gross. The Accutane cleared everything, but not until the 4th month I was on it. So be patient. I was obsessed with Accutane the first month I was on it, but then I just got used to taking it every day and barely thought about it. F 26 5 months
8/27/2008
 4  acne on face back and chest Dry everything!!!!! Nose ran continually while on it. Sleep issues! NO ONE MENTIONS THEIR BLOOD WORK HERE!!!!! My Triglycerides when from 165 to 277 Total Cholesterol from 174 to 206! Dermatologist insisted I take this on my very first visit. Did not ever try a topical medicine or antibiotic. I did NOT have cystic acne, but due to very sensitive skin I was having a lot of scaring on my face and back. It did improve my acne but I still get a few breakouts on chin and chest. I have read that the cholesterol and triglycerides should go down but they did not have me back for a blood test to confirm this. So I will have to do it on my own. F 20 9 months
4/18/2009
 4  Acne From week one until I finished the treatment: Dry chapped lips. From about 2 months on accutane and until I finished the treatment: Feeling og being tired and exhausted most of the time. Every now and then: Dry or watery or red eyes, stiffness: ancles, hips. Chest pain It cleared my acne after I had tried everything else. My skin hasn't been as soft as it is now since I was 12. But the side effects are horrible. I just finished my treatment. If the acne is gone forever or at least for 1 year or more it was worth it. F 24 132 days
60 1X day
11/11/2014
 4  Mild Acne on Face Back pain while lying down, mild. Fatigue constantly ... Showing signs of slight depression. Sleep alot. Dry lips and skin. Burning sensation in scalp, hair isn't oily at all anymore. Dry nose. Very dry eyes, got pink eye twice and have red eyes daily. Poop normal .. Lol so far I'm fine and see improvements, these side effects are easy to live with, you just gotta have faith. F 19 2 months
40 mg
10/20/2014
 4  Pretty bad acne on face Back is a bit sore, sometimes headaches, lots of poo (maybe it's just me that's been going on before I took this) peeling skin on my face, chapped lips (the corners of my lips are the worst at the moment) constantly sleepy (but I'm always sleepy being a teen) If you want the results you want, then you should deal with the pain. Many good things come with a cost. It may not be for everyone. Hell, I don't even know if I will get the FULL results with me being on 3 more medications. It's been only a few weeks so far, and it's actually doing well, therefore I would recommend this. F 14 1 months
forgot .-. 1X day
10/27/2014
 4  Moderate but persistent acne Dry skin, peeling lips, pain in rib cage, night sweats, eye dryness and irritation, joint pain, fatigue, muscle soreness. Results have been good for my skin. Looks good. I'm worried it is aging me but I am still on it and so I'm not sure what it will be when I'm finished. My skin cleared up in the first month and I'm on month 5 now. My doc believes I need 6 months for results to be more permanent. F 39 6 months
40 mg 2x
4/15/2014
 4  acne Bloody nose, back aches, dry skin, eyes burning, lips cracking I just use a cotton swab and dip it in vaseline or vaporub for bloody noses and also my lips it works great! Everyone tells me they see results in my face had acne since 11 and barely turning 17 and still have it and I also got dermabrasion and that also helped my skin scrapped off all the skin I didn't need!I do have alot of redness under makeup also but that should go away after my treatment. F 16 2 months
40 mg
3/27/2014
 4  Acne from severe to moderate Dry lips, dry skin, lethargy and headaches. This drug seems to be working very well - I have put off taking it for about 18 years or so. I have pimples every day but nowhere as bad as they used to be. My skin is almost clear except for a single pimple and ever present blackheads. When I started taking it, I already had a history of depression and Irritable Bowel Syndrome but it seems as if the aforementioned conditions have not be aggravated by this. I find that taking a B Complex with Vitamin C & 1000iu Vitamin E help with the side effects. Always take the pill with a meal and a full glass of liquid. I have also been using Bio Oil for dryness and scars. I am on a low dose 20mg so maybe that could explain the lack of severe side effects. I have been able to exercise and wear my contact lenses throughout the month or so that I have been taking it. I will see what the future effects are & I have been so afraid to take this drug because of the side effects but nobody that I know who has taken this drug has any of these long term side effects so maybe it depends on the luck of the draw. Good luck to all those taking it but I really think that this should be a last resort... F 28 1.5 months
10/9/2009
 4  Oily skin/mild acne Dry eyes, scalp, and arms. Mild tummy aches and constipation. More breakouts experienced within first couple of weeks of treatment. I have been on the 60 mg dose for about 2 weeks now and have been handling it quite well. My dermatologist had warned me that dry skin would occur and muscle soreness may also occur. So far, I have not experienced any muscle or joint soreness but I have noticed my eyes and scalp to be very dry and itchy. I haven't had any hair loss, but I can tell you, I have wanted to rip my hair out with how itchy my scalp has been. Lips have been a bit chapped but I have been using Burt's Bees which pretty much has knocked that out. My tummy has gotten a bit sore more than often and I have experienced a little constipation, I will try to drink more water. Everyone has different side effects when taking this medicine; I wouldn't assume that everything you read will happen to you. I haven't seen too much of a difference, in fact, my acne has gotten worse within the first week and a half, but it's starting to clear. F 23 2 weeks
10/23/2009
 4  Mild Acne- Hated The Blackheads I have only been on this treatment for 2 weeks and i am feeling rough. My twin sister was on this for 6 months last year and only experienced the basics side affects that everyone seems to get no matter what...extremely dry lips & face and the occasional mood swing. However she was started on a lower dose then me even though her acne was alot worse. I thought id be fine but im really not. I have upper back pain most of the time and the occasional chest pain. I get blurred vision and my eyes are killing me! Headaches on and off and im tired alot of the time,which doesnt change much actually as i do shift work but it is making it hard. Im definately not coming off the medication as i know it works but i know its gonna be difficult. Im just hoping that these are all i get. I can handle mood swings and the dry lips & face, just not the constant pain and the headaches. I would still recommend it as not everyone gets the same problems....my twin is the prime example.....she sailed through!!! She looks radiant and i hate her for it! :-P My sister is just generelly better now, psycially and mentally then she has ever been. F 20
10/22/2009
 4  acne dry skin ovarian cyst? this worked great for my acne, had only crazy dryness. My skin is very soft. About a month after I finished my 6 months, I had an ovarian cyst...not sure if it was caused by the medicine or not..but I ended up loosing my right ovary and fallopian tube! Sucks cuz I am only 15 and now I am scared I won't be able to have kids, because I have a couple of cysts on my other ovary too. Anyone else have this problem? F 15 6 months
10/27/2009
Email
 4  cystic acne Dry skin, chopped lips, constipation,increase of appetite, Mood swings, dry eyes, fatigue, back pain and recently left hip pain going all the way down to my heel. I m on the first week on my 4 month of accutane, my back cleared up completly with just one zit or two left but everything else is gone. My face is 90% clear now. however i am scaredthat i have developped a hip pain on my left side...-i don`t want it to be sth permanent! F 28 4 months
12/12/2009
Email
 4  Server cystic acne Out of the blue my nose would just start bleeding, going into the sun would make my skin red, skin on lips would peel off an entire layer at once, scalp was very dry as was face. It cleared up my acne but it came back did one more round and it came back again. F 32 1 months
30 2X day
12/22/2013
Email
 4  Adult acne Extremely dry skin on my face, dry scalp, chapped lips, joint/muscle pain. Neosporin Lip Health is the best thing I have found for my lips. I took Accutane about 10 years ago with only the dry skin and chapped lips to contend with. I am into my 2nd week and my lips are very dry and this time I have horrible back pain and stiffness in my hips and ankles. The stiffness does go away after I have gotten up and walked around. I have found a fantastic OTC chapstick that helps better than Vaseline. The Neosporin Lip Health is fantastic!!! I have also been using the Walgreens Shea Butter Vaseline on my face/inside my nose at night. It has been helping. Since I knew what to expect I was prepared for the side effects. It does get better!!! I am thankful that my sister is a massage therapist and that is helping with the sore muscles. F 28 14 days
12/27/2009
Email
 4  cystic acne dryness of lips and face. looking back probably depression I took Accutane in 1981-82. I had to have 2 rounds of the medicine but I do not remember the dosage. The first round cleared up my back and shoulders but it took another round to clear the cystic acne on my face. The only thing I do remember was the dryness and sensitivity to the sun. But since then I have dealt with depression through out my adult life. I don't remember the joint/muscle pain but getting older or what I have had creeky knees and such for a long time. My daughter,who took it at the age of 16-17 still has break outs and I am concerned about her taking it again. I would like to hear feedback on how the medicine has affected females and their hormones. I think that rather than losing hair it has messed mine and my daughter's hormones up and has caused an increase in thicker/darker body hair especially arms and chin. I went into early menopause at the age of 36 and have a thyroid condition. I don't know if these things are related to taking Accutane but I would like to find out if others have experienced anything similar. F 45 4 months
1/21/2010
 4  Cystic acne Very dry lips, dry skin. No negative mood changes, if anything it improved my mood. This drug made me feel amazing when I was on it. I called it my "beauty pill" gave me such confidence. No more oily skin or scalp. Only downsides were the dry lips and the routine blood tests. I recommend this to anyone suffering from acne! It's a wonder thing! F 27 2 years
30 mg
5/24/2015
 4  Acne, acne scars Dry everything.. Skin, nose, hair... Sore joint..... Little bit of mood swings ( I found I didn't want to leave the house much which is totally cool.. Lots of Netflix!) Dry lips and face are the worst thing. The skin around my nose became extremely sensitive and would burn even with cream. For face I used cetaphil moisturizer, and for lips I use aquaphor.. Overall- im happy- acne is terrible and although this is a very rough program I think it is worth it. You can't reLly conplain about how bad it is , when you take this medication you sign saying you acknowledge all of the side effects.. F 17 4 months
60mg
3/17/2017

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