ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Acne When I was on treatment before I can't really remember if I had side affects but I do remember having some days were it felt like everything just wasn't going right and I would cry but sure we have them days anyway! Oh yes dry skin which is the first side affect to notice and your acne may get worst b4 better but that just shows the treatment is working :) It's my first day of treatment and I can't wait for the end result as I was on these before they REALLY! Do work why has my acne come back I don't know but hopefully this will be the last time on treatment so ill keep posted on my journey to clear skin :) F 27 1 days
30mg
3/31/2015
Email
 5  moderate-severe acne chapped lips, dry skin I took 60mg of accutane for 10 months, 8 years ago. It was the only thing that worked with my skin after years of other medications. I was highly involved in sports at the time and noticed no aches or pains except those natural to the workouts and conditioning I was doing. Even my chapped lips and skin were't that bad. (I remember my doctor starting me at the lowest dose and upping it each visit until the 60mg dosage finally worked. And trust me, it was really obvious which dosage 'worked'. She said that a number of other doctors begin with high dosages and adjust from there, but the building up from a lower doseage was supposed to help combat some of the dryness and ensure I was using the lowest dosage possible for my skin). Anyway, I've been acne-free ever since. I still have dry skin (nothing a good moisturizer doesn't help), but have not had acne since (I can literally count on one hand the pimples I've had in the last 8 years). Accutane for me was a life-saver. My flawless skin (that I receive a number of compliments on being that I'm SNOW white, so any blemish would show) is the only indication of my time on this drug. I would recommend to anyone dealing with severe acne that he/she take with a (large) grain of salt many of the scares that are out there regarding this drug. F 23 10 months
1/12/2010
 5  cystic acne dry lips, dry cracking skin on arms and hands, nose bleeds inside of nose, mood swings, irritability, low libido, vaginal dryness. My skin got a little bit worse the first and second month, but cleared up after that. It has been amazing most of the time. I have been moody about things that would not normally bother me. I also do not want to do many things I once did. I cannot wash with body wash because my skin gets too dry, my lips are only bearable because of medicated chapstick and prescription medicine. I would recommend accutane but be ready for the side effects. I am counting down the days until I am done. I'm only on it because absolutely nothing else worked. I want my normal life back. F 22 4 months
1/6/2010
 5  Acne Dry lips, joint pain I took Accutane when I was 23, when it was first approved. It cleared up 13 years worth of acne in a few weeks, with few side effects. No lasting side effects.I took it again at age 40 but noticed severe joint pain, and discontinued after two months. I am taking it again at age 52 for the occasionall hormonal flair up and again have severe joint pain. I am slim, very active, work out, eat pretty well, don't smoke. The joint pain will go away once I stop the dug. For the other reviewers, please know they may not be revealing anything else about their lives: do they smoke? Drink? Take other drugs? Symptoms are different with each person and it's hard to say Accutane caused this or that. It might be, but other things may also be affecting ther symptoms. I know it is giving me joint pain, but every time I stopped it, I went back to working out, running, being in good shape. So you need to take care of yourself very well and not just blame Accutane right away. Every patient should dsicuss their treatment and side effects with their physician, as every patinet is unique and may experience things differently. F 52 3 months
12/20/2009
 5  severe acne Very dry lips and nose over all very dry Skin.full body itching dry couch ,mouth ulcers .mood swings.sore back. My 3rd time taking the medication this time side affects seem worse,but worth every minute of discomfort. As it truly is an amazing drug for acne,acne wasted so many years of mg life hidding a way or covering it up as good as i could with expensive makeup.knocked my confidence.however still not perfect but so much better and happier.so plzzzzz stick with it . F 28 5 days
40 mg 1X day
3/26/2013
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 5  pimples severe anxitey,mood swings,horrible stomache cramps,headaches if i didnt take it with food,dry skin, chapped lips,nosebleeds,hip pain, lower back pain, direahha works good but the side effects blow. and you have to know how to control them. F 19 5 months
11/2/2009
 5  Severe Acne Horrible mood swings, SEVERE dryness of the hands, arms, lips and face This cleared up acne that i had for over ten years! Its been 3 years since I stopped using ACCUTANE and i have received so many compliments on how beautiful my skin is, i never thought my nasty pizza face would ever look so good. HOWEVER--SERIOUS SIDE EFFECTS: you have to be lotioning yourself religiously, otherwise you will have nasty dry patches that begin to bleed from the severe dryness, my lips suffered the most, i looked like a crack addict. However, always carry around AQUAPHOR, it worked the best on my horrible dry spots. Also you will have angry fits of rage,..be careful! However after the treatment You will be glad you went through hell! F 22 6 months
11/4/2009
 5  Severe lifelong acne, cystic Aching joints, like arthritis, extremely stiff getting up or down, sitting or standing, but once motoring okay. Dry and chapped skin and dry hair, very tired, feel poisoned every time the dose goes up, increased cholesterol levels, skin heebie jeebies, sleeping problems - tired but could not sleep with crawling skin - lead to exhaustion. This is extreme medication, my doctor did not mess about and told me this. But I had extreme acne under control for most of my life but had exhausted every other cure and as a woman was really suffering from self esteem issues as it got worse, went down my back and chest and shoulders, my face could be used to frighten small children, and it always got worse under stress. The Accutane was like poison in my system, I feel sore and tired as if I am dragging myself around the whole time, eyes, skin hair nose ears dried out, vaseline my best friend....but the bottom line is it is a miracle cure for my skin and I can face the world again and smile at it, I am in my sixth month of taking accutane and my skin is wonderful, it was like getting a skin transplant. If it stays like this and the side effects go away it will have been well, well worth the six months of hard work. Will come back in six months time and update. F 42 5 months
9/2/2009
 5  severe acne dry skin, lips, nose; small rash on the back of my hands Wow! This drug has helped me a lot. I have been taking accutane for about a month and within the 2nd week I noticed an improvement in my skin. I am still taking this drug and everyday my face has cleared up more. Yes it does make your whole body dry you will need lots of chapstick. I reccomend aquaphor. Recently I have noticed a small rash with little red bumps on the back of my hand. This is a common side effect and these bumps go away with mosturizing lotion. I reccommend using this drug if your acne is affecting you life. I have a lot more confidence because my skin is clearer and it will continue to improve. Thank you accutane!!! F 16 1 months
10/7/2009
 5  Severe Acne Dry cracked lips, very dry face Accutane is a God send. It cured my severe acne in 4 months after trying EVERYTHING for 3 years. F 4 months
40MG 1X day
4/6/2014
 5  Yes This is my 2nd round. I took it over 15 years ago. horrible cystic acne from the deprovera (sp) shot. It cleared my skin. Dry lips and joint pain. However I had a baby and my acne came back but not as bad. This time- bloody nose and very dry lips..my lips are grey. Beauty know no pain. If you have tried everything and nothing has worked..give it a try. F 37 10 days
20 1X day
5/20/2014
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 5  Severe Cystic Acne Dry lips, bloody nose, extreme pain in my rib cage, severe night sweats (although that wasn't until month 4), rectal bleeding, hemroids, sweaty palms, eczema on the tops of my hands and my forearms, and slightly dry skin. It was all worth it though. I'd had acne for ten years, (since age 12) with nothing ever succeeding in clearing it up. With Accutane, my acne cleared up completely in month 2. Side effects were scary when I didn't know exactly what was happening, and they were inconvenient, but Accutane was my only hope and it changed my life for the better. F 22 4 months
30MG
6/19/2014
Email
 5  Acne on face, back and chest Thumb nail split right down the centre from top to bottom. Skin on my arms and legs got thin. I am 33, took the drug when I was 18. Although it completely cured my acne and made me a much happier person, I am now still suffering from side effects. The nail on my thumb still sometimes splits lengthways, although very rarely and it isn't really an issue, just looks horrid. But my main problem now is my skin on my arms and particularly my legs is so thin that I just scratch an itch and I draw blood. My legs look absolutely awful, so I tend to keep them covered. Which I suppose is better than having to cover my face and not being able to wear strappy tops etc. F 33 4 months
1X day
7/11/2014
Email
 5  severe acne dry skin everywhere, thinning of hair, extremely chapped lips, facial flushing. I absolutely loved taking accutane. It made me feel so much better about myself just 2 months into treatment. i recently got pregnant and my skin broke out terrible and it looks just like it does before accutane. I plan on going on a second course of accutane after i have my baby. this is truly a miracle drug. The side effects are worth it when you have clear skin in the end. The only pain about being on this drug is how expensive it is, and the fact that you need monthly drug tests. i can't wait to go on this drug again and clear my skin back up. F 20 5 months
40mg daily 1X day
9/3/2014
 5  Mild acne A bit of redness, dryness, chapped lips, bachake, and peely skin. This isn't for everyone, so do your research, ESPECIALLY if you're a woman. If you take any other meds, just go look up if it reacts with the other in a negative way. It's cleared me up great, only took about a month. F 19 5 months
40 1X day
10/29/2014
 5  Severe Cystic Acne I am now 10 days into my 2nd Accurane theory session. The first ended 9 years ago. I must say that in the last 9 yrs I didn't break out much until real recently which is why I'm on Accutane again. It cleared my face up like magic. I didn't the initial flare up I have been reading about back then. However this session I am badly. Nodules on my neck and under my chin. I am actually going tomorrow to get injections of Cortisone in an attempt to cure these nodules that only recently appeared. Other than dry lips I've had never side effects, just carry chap stick. I recently read about people saying they have sexual issues on the medication then manta yrs after stopping it; I myself have never experience such a thing. My sex life is very healthy and consistent. I plan to do it a 3rd time if need be. It is the acne magic pill! F 31 10 days
60 mg
1/26/2015
Email
 5  moderate - persistent acne. Dry lips, dry skin, dry hair (bonus), loss of hearing in left ear, lower back pain. After struggling with acne for 6 years I was referred to derm. I am only one month into my treatment and the results have been AMAZING. The first two weeks were bad: my skin flared up really bad and was scarlet red and felt like my skin was burning. I currently only have two cysts- one on each cheek. My skin is soo soft. All my blackheads have vanished already. I have my derm appointment tomorrow and I cannot wait! Definitely worth the side effects in my opinion. I feel much more confident and happy within myself already. F 25 1 months
30
2/14/2015
Email
 5  severe nodular acne SE:Mostly dry lips, skin and eyes but able to cont. wearing contacts.. I was in my early 20's in the 1980's. This was miracle drug for me. No more cysts! and skin looked great. I took 2 rounds of accutane over a year in the 80's. Prior to this creams, lotions, antibiotics and it just became worse for years. As far as depression, hormonal changes in life can cause depression as well as acne--they seem to occur together. A teenage with acne can be depressed. My father had severe acne and has deep scars. I believe that I avoided this because of Accutane. Accutane has gotten a bad wrap. I have had 3 healthy children several years after being on Accutane. If they develop acne I would put them on Accutane. At age 46, with menapause coming, I am now starting to have increase breakouts, rare cyst. If it becomes bad, I would go back on Accutane. My skin for 20yrs has remained healthy until just recently. Even with breakouts now, I do not have oiliness. My pores recently seem to be enlarging and my skin has become thinner ...probably age and hormone changes. F 46 12 months
5/2/2009
 5  mild persistent acne Very dry, peeling lips. Dry skin that sunburns quickly. Dry eyes. Mild joint pain in knees. Itchy flaky scalp for the first few weeks. Dry nose with occasional nosebleeds The severity of my acne was mild to moderate, but after trying several different topical medications of increasing strengths, and even adding oral antibiotics, I did not see any significant improvement so my dr. prescribed accutane. If you are female, getting the drug is a real PITA due to the repeated pregnancy tests and the iPledge program. The side effects are also very annoying and I needed to keep lots of moisturizers, eye drops, and lip balm on hand. But, it worked wonders to clear my skin where nothing else had helped, and despite all the hassle I'm really glad I took Accutane because even now 6 months after treatment my skin is still clear. F 30 5 months
4/11/2009
 5  acne Very very dry lips (keep chapsticks all over the place!), sensitivity to sun but not terrible, very minor joint pain. My daughter, age 14, just finished 5 months of Accutane/Sotret is the generic, (after four miserable years of every antibiotic and topical treatment, laser therapy and naturopathic remedies) - FINALLY her skin is CLEAR and she is thrilled with the results. Beforehand I had read askapatient.com comments plus other info and I was scared about hairloss, depression, jointpain, etc.so I was very reluctant for her, especially at her age, to go on Accutane. But after everything she had tried, she was so discouraged and selfconscious; her dermatologist said that she has treated patients with Accutane for 20+ years with very very minor problems,(it turns out the same ones that our daughter had), almost everyone was pleased with the results so we decided to go for it. Relative to everything else our daughter tried, this has been an easy treatment, (the real hassle is the FDA requirements of monthly blood tests and online questions which seem ridiculous). Her clear skin has made a huge differ F 14 5 months
8/28/2008

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