ACCUTANE Reviews (ISOTRETINOIN)

Average Rating: 3.3 (746 Ratings)

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 DERMATOLOGICS

 Type: Brand name discontinued; available as generic

  

ACCUTANE  (ISOTRETINOIN):  This medication is used to treat severe cystic acne (also known as nodular acne) that has not responded to other treatment (e.g., benzoyl peroxide or clindamycin applied to the skin or tetracycline or minocycline taken by mouth). It belongs to a class of drugs known as retinoids. It works by decreasing facial oil (sebum) production. High amounts of sebum can lead to severe acne. If left untreated, severe acne may cause permanent scarring.   FDA Approval Date: 1982-05-07 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ACCUTANE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ACCUTANECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  ACNE Dryish lips, musle and bone soreness, crying for no reason which I never do or did before. I was on a half does & it did not seem that bad while I was on it. But I have to warn you that this drug can cause PERMANENT DAMAGE! You know something is bad if major health insurance like Blue Cross will not insure you for sometime after you take this drug. This should absolutely be a last resort. I have permanent eye damage definately caused by this drug! It also caused liver damage and I got Jaundice even though I got blood tested every month, I sweat a lot more than I did before I took it and my skin is now drier but not in a good way and my mood stability/focus never went back to normal. I was 20-21 at the time and I drank a ton of water, ate super healthy, worked out 30-40 min. 5 days a week. I had no previous history of any health problems, nor did my parents and I was not taking any other drugs. Please try everything else 1st,this has to be a last resort!It is soo toxic! I mean-eat healthier, multivitamin,Zinc,Omega-3's, lower stress level with meditation or something,good facials, DERMALOGICA Anti-Bac wash ,Skin Ceuticals C+E serum, oil control serum and oil free sunscreen in morining,Dermacia or Mineral makeup only!BP wash at night,Salicylic acid 2%+, glycolic acid toner, calming masks etc. Always look at the ingredient, funky F 23 6 months
12/7/2006
 4  chronic acne dry lips, joint pain, rash on the backs of hands and arms i'm in my 4th month (of 6) on the medication and it's doing wonders for the problem acne i had on my face. unfortunately, it comes at a cost: i hardly had any side effects in my first 3 months when i was on 10-20 mgs a day. but my skin freaked out when my derm increased the dosage to 40 mg/day - that's when this rash, which is pretty unsightly, started appearing on my hands and arms. also, i'm a runner and so the joint pain in my knees is starting to effect that a little. my face is doing great though - a stray pimple maybe that disappears almost as quick as it came. i'm told the rash is temporary and my derm recommended cerave lotion and cleanser to help. oh and very dry lips - i think i've been through 5 sticks of chapstick already! but the side effects are only temporary, and the results will hopefully be permenant. F 25 4 months
5/4/2006
 4  moderate acne I have chapped lips. I also have minor joint pain in my fingers when I play guitar. I have lived with acne since my teen years and now I'm 30. I told my doctor I can't see having acne and wrinkles! I had these little bumps all over my face and it made me feel dirty. I would also get a huge pimple, then it would go away, then I would get another, and it would go away.... So I would always have at least one huge leision on my face. I still have one large pimple on my neck, but the little bumps are disappearing and my skin is so much smoother. So far, so good! F 30 10 days
7/7/2006
 4  acne Dry Lips, Vaginal dryness, decrease in sexual arousement, dry eyes My acne cleared up excellent, was it worth it, yes. I have to say my acne did come back after using accutane for 1 year. i will be starting it again soon. I have tried everthing in the book and nothing helped except accutane. F 25 1 months
7/27/2006
 4  Acne Dry, peeling skin and very chapped lips. Decreased night vision. Back and chest pain. Accutane does have some serious side effects, and is not for everyone, but if you can stand the dry skin, then it is a great drug! Completely cleared my acne! F 25 4 months
6/7/2006
 4  cystic acne I have recently ended my near 1 year run with accutane. It really geared me towards a healthier lifestyle, which was great. There have been some negative side effects, however. The dryness is most notable. Every morning (more so now than when I was on the med), dry throat, nose, EYES, skin. Also, there have been some new pimples showing up, which I'm getting totally scared about. My digestion is kind of funny as well, sometimes I'll feel extremely sick if I don't get water. All in all, I fully recommend accutane as a LAST RESORT because my skin did clear up remarkably (after months of dedication to the drug) Try other meds first, stick with them, be consistent, and DONT GIVE UP. Accutane is no miracle...it takes a confident person who's willing to make a lifestyle change. F 24 11 days
1/21/2007
 4  cystic acne I have recently ended my near 1 year run with accutane. It really geared me towards a healthier lifestyle, which was great. There have been some negative side effects, however. The dryness is most notable. Every morning (more so now than when I was on the med), dry throat, nose, EYES, skin. Also, there have been some new pimples showing up, which I'm getting totally scared about. My digestion is kind of funny as well, sometimes I'll feel extremely sick if I don't get water. All in all, I fully recommend accutane as a LAST RESORT because my skin did clear up remarkably (after months of dedication to the drug) Try other meds first, stick with them, be consistent, and DONT GIVE UP. Accutane is no miracle...it takes a confident person who's willing to make a lifestyle change. F 24 11 days
1/21/2007
 4  moderate acne Dry, peeling lips. Dry skin on face & ears. Lower back pain, dry red rash on arms & hands Accutane is supposedly a wonder drug but I am still waiting for the miracle. My face overall has improved but I still have large areas of acne on the cheeks. I am 7 weeks into treatment and was told that 'it should start melting off'. Im waiting. The side effects are not unbearable but they are uncomfortable. Lips are not as tender and peeling as before, but still very dry. The lower back pain is not getting better, have had it for about a month now. Skin on my ears peels off which is odd. It doesn't hurt, just looks weird. I dont know if I will continue through the entire course of treatment (21 weeks). Im only a third of the way through and if the side effects dont start going away I may give up. I do think the medicine is working, but not as quickly as I have heard with others. F 18 7 weeks
2/12/2006
 4  acne very dry lips, dry scalp, dry eyes, headaches, moodiness Please be patient this medicine works wonderfully. If you are like me and are not some of the fortunate who clear up after two weeks of taking this medicine, just keep taking it and be patient. My acne got so bad for the first couple of months of taking this medicine that I didnt even want to leave my house. but now after four months my skin is completely clear. I have however experience a slight mood change. And I honestly can not wait until I am free from having to take this medicine and just have beautiful clear skin. Its worth it and I thank God that this medicine exists, it has saved me from a lot of self doubt. F 24 4 months
11/22/2006
 4  moderate cystic acne on face very dry lips and nose, developed skin rash on backs of hands and arms, body aches especially in my knees your skin looks phenomenal when you're on the medication - dryness and other side effects aside. but don't expect your skin to stay that way once you're done with treatment, i've been off the medication for about 3 months, and almost right away, my skin returned to the same oiliness it had been before i started the treatment. that was really disappointing, and now, i'm starting to get small pin-head sized pimples on my face again. don't get me wrong, the medication made my acne a lot less severe than it used to be, but it doesn't work miracles. i'm actually worried that my acne will continue to get worse again as time passes, and my derm told me that she wouldn't put me on accutane again if i "relapsed". bear that in mind when you're deciding whether or not to start taking accutane - it may not be worth it. F 26 5 months
11/8/2006
 4  acne dry throat made me cough frequently, dry nose, dry and cracked lips F 45 4 months
8/23/2005
 4  Lifelong acne blepharitis (inflammation of eyelids), hair loss, dry eye, dry lips. (I'm the 58 yr. old woman who did the earlier posting, when I was only several weeks into therapy. Here's the rest of the story.) I took Accutane for 4.5 months. I had to reduce the dose after about 2 months, when the eyelid inflammation flared up. I went from 40 mg. down to 20 mg. day. I've been off for about 1 month and I still have the eyelid inflammation (although it seems a little better, but not much) and the hair loss continues. My skin is still clear and I am very happy about that. The acne is completely gone -- no breakouts at all on my face, back, neck, chest. Some mild oiliness has returned to my face -- but it is definitely within the normal range. Overall, I am satisfied -- but I had, and continue to have, definite side effects. So you need to be aware there are risks connected to this drug and some side effects may continue after you stop the drug. I'm certainly hoping that the eyelid inflammation and the hair loss cease with the passage of time. Who knows? F 58 4.5 months
10/30/2005
 4  Acne that created scars 1- Severe Chapped lips, The only brand that helped what Chapstick. 2- Nose dryness, and occassional bleeding, I applied liquid glycerin once in every two days. 3- Face dryness, treated by moisturizer 4- face sensitiviy to sun (sunblock). 5- dry patches, and small rash spots on my arms. 6- loss of tastes. 7- Minimal back pain. 8- Eye Dryness ( used artificial tears). I wish I had experienced some weight loss as some people have ;) 8- Dry hair. Supposidly this is my last month (th 5th), but till now I am not 100% satisfied with the texture of my skin. I have lost all acne expect for one huge under the skin bump, that is not going away. My skin doesn't look as smooth as I thought it would. Still not comfortable taking close-up pictures. F 23 5 months
8/29/2006
 4  Severe acne Extremely dry lips, Crusty nose but no bleeds, severe back pain, long-lasting headaches, reduced night vision, loss of hearing, lots of fatigue, joint pain, overall dry skin, mood swings, crying spells, weird earwax The dry lips started after about 5 days, the back pain was really bad when i got into bed at nite but faded after 15 minutes... So far, I havent gotten any new blemishes. slowly its clearing up.... I really cant handle the side effects tho... sumtimes so bad i had to stay in bed.. F 17 4 weeks
9/26/2006
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 4  acne I have been off of Accutane for almost 6 years now...During and after taking Accutane, I experienced a serious loss of vision which has turned out to be permanent and is getting worse. My acne became seriously worse for a long time before it got better. I developed and still have digestive problems and urinary problems, but the urinary problems may have been from before. The texture of my hair changed; my hair went from thick and straight to very thin and curly. It didn't change back until after I stopped taking Accutane. I did get slightly depressed, but I do not contribute it to the Accutane. I think I was upset that the medicine wasn't working as I had hoped. BUT...today, my skin is clear as a baby's butt, and I couldn't be happier....except for the side effects I am STILL experiencing. F 22 2 years
8/11/2006
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 4  Severe Adult Acne Extremely dry skin. Dry lips, dry cracked lining of nose (but no bleeding) EXTREME PAIN!!!! After I had my second child, I developed severe acne. Huge cysts all over my face. I actually had someone ask me if I had the chickenpox. I never looked anyone in the face I was so embarrassed. I was on Minocyn (Antibiotics) for about four years and then they just stopped working. Accutane was my last option. Being a brittle diabetic, this wasn't the best option for me but I didn't know what else to do. My acne got much, much worse when I first started, but I knew to expect that as my doctor went over all of the side effect with me. My acne cleared up comepletely. I haven't had a pimple since I stopped taking it. The pain however, is unbearable. I can't move my neck to either side, I can't rotate my left hip outward and my left arm is completely useless. I can't even dress myself anymore. I can't put my hair up anymore(and it's extremely long). When I say I have pain, I don't mean it kinda hurts, I mean it's excrutiating. It limits me in every thing I do. I can't go to F 30 5 months
8/15/2006
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 4  cystic acne dry skin and lips, little but no severe egzama, slow healing, a little depression at first. i heard about Accutane from my dermatologist and heard that it works. My dermatologist himself had taken Accutane when he was 17 and he said it works amazing,and hes now in his 30s and his skin looks great. So i decided to try it out. Im now 4 months and 3 weeks into the treatment and my skin has improved dramaticly and im so excited. There is a possibility that i might have to go a 6th month but if i have to.. thats what im willing to do cause id rather get it all out then just get most of it. Accutane isnt for everyone.. but if youve heard enough good things about it and it has convinced you, thats a commitment you make with yourself. F 18 4.7 months
10/12/2008
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 4  cystic acne Dryness of lips, eyes, mouth, etc. HAIR LOSS. Triglyceride and cholesterol increases while on the drug. I took accutane when I was 15, and now I am 22. Seven years later, my skin is great. I love it, and I use Retin-A topically to keep recurring acne down, because I do not want to be on accutane again. Warning: MY HAIR IS VERY THIN NOW, and my Dr. told me it would grow back. IT DID NOT! I used to have a very thick head of hair, now it is about half its original thickness. NOTHING WILL GROW IT BACK. However, that is a sacrifice I am somewhat willing to make because of how bad my skin was before. I am still mad about it though because I have to volumize now, which was never a problem before. My doctor gave me the long list of side effects, but I don't recall being told about the hair loss. It came as a surprise to me. F 22 5 months
10/3/2006
 4  fore acne my skin is very dry and i have sever hairloss and hyrsutism my hairloss has been continued within 3 years ago and i think i will loss whole of my hairs . F 31 6 months
5/7/2003
 4  ACNE DRY LIPS, HAIR HAS NO OIL IN IT, WHICH WAS NICE. EYES GOT A BIT DRY, BROKE OUT THE FIRST 6 WEEKS I WAS TAKING IT. F 22 4 months
12/29/2004

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